Kenneth J Chang

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint In vivo visualization of epidermal growth factor receptor and survivin expression in porcine pancreas using endoscopic ultrasound guided fine needle imaging with confocal laser-induced endomicroscopy
    Y Nakai
    Division of Gastroenterology and Hepatology, H H Chao Comprehensive Digestive Disease Center, University of California, Irvine School of Medicine, CA, USA
    J Physiol Pharmacol 63:577-80. 2012
  2. doi request reprint Endo-hepatology: a new paradigm
    Kenneth J Chang
    Division of Gastroenterology and Hepatology, H H Chao Comprehensive Digestive Disease Center, University of California, Irvine, 101 The City Drive, Orange, CA 92868, USA
    Gastrointest Endosc Clin N Am 22:379-85, xi. 2012
  3. ncbi request reprint Molecular imaging of epidermal growth factor-receptor and survivin in vivo in porcine esophageal and gastric mucosae using probe-based confocal laser-induced endomicroscopy: proof of concept
    Y Nakai
    Division of Gastroenterology and Hepatology, H H Chao Comprehensive Digestive Disease Center, University of California, Irvine, School of Medicine, CA, USA
    J Physiol Pharmacol 63:303-7. 2012
  4. ncbi request reprint Risk of pancreatic adenocarcinoma: disparity between African Americans and other race/ethnic groups
    Kenneth J Chang
    Division of Gastroenterology, Department of Medicine, University of California, Irvine Medical Center, Orange, California 92868 3298, USA
    Cancer 103:349-57. 2005
  5. ncbi request reprint Impact of endoscopic ultrasound combined with fine-needle aspiration biopsy in the management of esophageal cancer
    K J Chang
    Dept of Medicine, Division of Gastroenterology, Gastrointestinal Oncology Section, University of California, Irvine Medical Center, Orange, California 92868, USA
    Endoscopy 35:962-6. 2003
  6. doi request reprint Endoscopic ultrasound delivery of an antitumor agent to treat a case of pancreatic cancer
    Kenneth J Chang
    Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, Room 106, First Floor, Building 22C, 101 The City Drive, Orange, CA 92868 3298, USA
    Nat Clin Pract Gastroenterol Hepatol 5:107-11. 2008
  7. ncbi request reprint EUS-guided fine needle injection (FNI) and anti-tumor therapy
    K J Chang
    University of California, Irvine, USA
    Endoscopy 38:S88-93. 2006
  8. ncbi request reprint State of the art lecture: endoscopic ultrasound (EUS) and FNA in pancreatico-biliary tumors
    K J Chang
    University of California, Irvine, USA
    Endoscopy 38:S56-60. 2006
  9. ncbi request reprint Staging accuracy of endoscopic ultrasound based on pathologic analysis after minimally invasive esophagectomy
    Brian R Smith
    Department of Surgery, University of California, Irvine Medical Center, Orange, California 92868, USA
    Am Surg 76:1228-31. 2010
  10. ncbi request reprint Endoscopic ultrasound-guided fine-needle injection
    Jason B Klapman
    Division of Gastroenterology, University of California Irvine Medical Center, 101 The City Drive, Building 22C, Route 99, Orange, California 92868, USA
    Gastrointest Endosc Clin N Am 15:169-77, x. 2005

Collaborators

Detail Information

Publications43

  1. ncbi request reprint In vivo visualization of epidermal growth factor receptor and survivin expression in porcine pancreas using endoscopic ultrasound guided fine needle imaging with confocal laser-induced endomicroscopy
    Y Nakai
    Division of Gastroenterology and Hepatology, H H Chao Comprehensive Digestive Disease Center, University of California, Irvine School of Medicine, CA, USA
    J Physiol Pharmacol 63:577-80. 2012
    ..Then pigs were euthanized and specimens of pancreas from areas injected with antibodies were obtained for histologic examination under epifluorescence microscope...
  2. doi request reprint Endo-hepatology: a new paradigm
    Kenneth J Chang
    Division of Gastroenterology and Hepatology, H H Chao Comprehensive Digestive Disease Center, University of California, Irvine, 101 The City Drive, Orange, CA 92868, USA
    Gastrointest Endosc Clin N Am 22:379-85, xi. 2012
    ..The authors like to consider this area of integration or overlap of endoscopic procedures within the practice of hepatology as endo-hepatology...
  3. ncbi request reprint Molecular imaging of epidermal growth factor-receptor and survivin in vivo in porcine esophageal and gastric mucosae using probe-based confocal laser-induced endomicroscopy: proof of concept
    Y Nakai
    Division of Gastroenterology and Hepatology, H H Chao Comprehensive Digestive Disease Center, University of California, Irvine, School of Medicine, CA, USA
    J Physiol Pharmacol 63:303-7. 2012
    ..Then the pigs were euthanized and esophageal and gastric walls from the areas sprayed or injected with antibodies were collected for histologic examination under epifluorescence microscopy...
  4. ncbi request reprint Risk of pancreatic adenocarcinoma: disparity between African Americans and other race/ethnic groups
    Kenneth J Chang
    Division of Gastroenterology, Department of Medicine, University of California, Irvine Medical Center, Orange, California 92868 3298, USA
    Cancer 103:349-57. 2005
    ..African Americans have a higher incidence of pancreatic adenocarcinoma compared with non-Hispanic whites. Whether other clinical differences exist between these two groups is not well known...
  5. ncbi request reprint Impact of endoscopic ultrasound combined with fine-needle aspiration biopsy in the management of esophageal cancer
    K J Chang
    Dept of Medicine, Division of Gastroenterology, Gastrointestinal Oncology Section, University of California, Irvine Medical Center, Orange, California 92868, USA
    Endoscopy 35:962-6. 2003
    ..Its impact on medical decision-making and the cost of care is unknown. This prospective case series was undertaken in order to determine the impact of EUS in combination with FNA on patients' choice of therapy and on the cost of care...
  6. doi request reprint Endoscopic ultrasound delivery of an antitumor agent to treat a case of pancreatic cancer
    Kenneth J Chang
    Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, Room 106, First Floor, Building 22C, 101 The City Drive, Orange, CA 92868 3298, USA
    Nat Clin Pract Gastroenterol Hepatol 5:107-11. 2008
    ..A CT scan suggested that the patient had a mass in his pancreas and he was referred for further diagnostic work-up, staging and treatment...
  7. ncbi request reprint EUS-guided fine needle injection (FNI) and anti-tumor therapy
    K J Chang
    University of California, Irvine, USA
    Endoscopy 38:S88-93. 2006
  8. ncbi request reprint State of the art lecture: endoscopic ultrasound (EUS) and FNA in pancreatico-biliary tumors
    K J Chang
    University of California, Irvine, USA
    Endoscopy 38:S56-60. 2006
  9. ncbi request reprint Staging accuracy of endoscopic ultrasound based on pathologic analysis after minimally invasive esophagectomy
    Brian R Smith
    Department of Surgery, University of California, Irvine Medical Center, Orange, California 92868, USA
    Am Surg 76:1228-31. 2010
    ..The accuracy for T and N staging is less reliable after neoadjuvant therapy...
  10. ncbi request reprint Endoscopic ultrasound-guided fine-needle injection
    Jason B Klapman
    Division of Gastroenterology, University of California Irvine Medical Center, 101 The City Drive, Building 22C, Route 99, Orange, California 92868, USA
    Gastrointest Endosc Clin N Am 15:169-77, x. 2005
    ..The involvement of EUS-guided FNI in tumor therapy adds a host of potential new applications that continue to swing the pendulum of EUS from a diagnostic to a therapeutic modality...
  11. doi request reprint Interventional EUS for the treatment of pancreatic cancer
    Reiko Ashida
    Irvine Medical Center, H H Chao Comprehensive Digestive Disease Center, University of California, 101 The City Drive, Orange, CA 92868, USA
    J Hepatobiliary Pancreat Surg 16:592-7. 2009
    ..This review will focus on interventional EUS in the treatment of pancreatic cancer...
  12. doi request reprint High single-pass diagnostic yield of a new 25-gauge core biopsy needle for EUS-guided FNA biopsy in solid pancreatic lesions
    Takuji Iwashita
    H H Chao Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, Orange, California 92868, USA
    Gastrointest Endosc 77:909-15. 2013
    ..Current limitations of EUS-guided FNA include the need for multiple passes and on-site cytology assessment and lack of core specimen. Recently, a new 25-gauge core biopsy needle (PC25) was developed to overcome these limitations...
  13. pmc Phase I evaluation of TNFerade biologic plus chemoradiotherapy before esophagectomy for locally advanced resectable esophageal cancer
    Kenneth J Chang
    University of California, Irvine, H H Chao Comprehensive Digestive Disease Center, Orange, California, USA
    Gastrointest Endosc 75:1139-46.e2. 2012
    ..This multicenter phase I trial examined intratumoral injection of TNFerade biologic, an adenoviral vector that expresses the human tumor necrosis factor-α gene, with chemoradiotherapy in locally advanced esophageal cancer...
  14. ncbi request reprint EUS-guided brachytherapy
    John J Lah
    Division of Gastroenterology and Department of Radiation Oncology, University of California, Irvine Medical Center, Orange, California 92868, USA
    Gastrointest Endosc 62:805-8. 2005
  15. doi request reprint In vivo imaging of porcine gastric enteric nervous system using confocal laser endomicroscopy &molecular neuronal probe
    Jason B Samarasena
    Division of Gastroenterology and Hepatology, Department of Medicine, University of California Irvine, Orange
    J Gastroenterol Hepatol 31:802-7. 2016
    ..Our aim was to determine the feasibility of in vivo visualization of GENS in the porcine stomach using endoscopic ultrasound (EUS) guided nCLE and local injection of molecular neuronal probe NeuroTrace...
  16. doi request reprint Endoscopic ultrasound-guided antitumor agents
    Yousuke Nakai
    Division of Gastroenterology and Hepatology, H H Chao Comprehensive Digestive Disease Center, University of California, Irvine, 101 The City Drive, Orange, CA 92868, USA
    Gastrointest Endosc Clin N Am 22:315-24, x. 2012
    ..The evidence of the feasibility of EUS-FNI of antitumor agents has been expanding with promising results...
  17. doi request reprint Newly-developed, forward-viewing echoendoscope: a comparative pilot study to the standard echoendoscope in the imaging of abdominal organs and feasibility of endoscopic ultrasound-guided interventions
    Takuji Iwashita
    HH Chao Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, Orange, California 92868, USA
    J Gastroenterol Hepatol 27:362-7. 2012
    ..The aim of this study was to compare the FV-CLA echoendoscope to the OV-CLA echoendoscope for EUS imaging of abdominal organs, and to assess the feasibility of EUS-guided interventions using the FV-CLA echoendoscope...
  18. doi request reprint Role of serial EUS-guided FNA on pancreatic cystic neoplasms: a retrospective analysis of repeat carcinoembryonic antigen measurements
    Yousuke Nakai
    H H Chao Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, Orange, California, USA
    Gastrointest Endosc 84:780-784. 2016
    ..The aim of this analysis is to evaluate the potential clinical significance of serial carcinoembryonic antigen (CEA) measurements by EUS-guided FNA (EUS-FNA) in the surveillance for PCNs...
  19. doi request reprint Diagnosis of pancreatic cysts: EUS-guided, through-the-needle confocal laser-induced endomicroscopy and cystoscopy trial: DETECT study
    Yousuke Nakai
    H H Chao Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, Orange, California, USA
    Gastrointest Endosc 81:1204-14. 2015
    ..The combination of cystoscopy by using a through-the-needle fiberoptic probe in combination with nCLE under EUS guidance may improve the diagnosis of PCNs...
  20. doi request reprint EUS-guided portal pressure gradient measurement with a simple novel device: a human pilot study
    Jason Y Huang
    H H Chao Comprehensive Digestive Disease Center, Division of Gastroenterology and Hepatology, University of California, Irvine
    Gastrointest Endosc . 2016
    ..Our animal studies showed excellent correlation between EUS-PPGM and IR-PPGM. We now present the first human pilot study of EUS-PPGM in patients with liver disease...
  21. doi request reprint Endoscopic ultrasonography-guided fine-needle aspiration of pancreatic cystic lesions: a practical approach to diagnosis and management
    Jason B Samarasena
    Division of Gastroenterology and Hepatology, H H Chao Comprehensive Digestive Disease Center, University of California, Irvine, 101 The City Drive, Orange, CA 92868, USA
    Gastrointest Endosc Clin N Am 22:169-85, vii. 2012
    ..Future work with molecular analysis of cyst fluid, direct cystoscopy, and confocal laser endomicroscopy will likely further enhance the diagnostic accuracy of these lesions...
  22. ncbi request reprint EUS in combination with fine-needle injection celiac plexus neurolysis from within a Wallstent stent
    Roy M Soetikno
    Division of Gastrointestinal Oncology, University of California, Irvine, Orange, California, USA
    Gastrointest Endosc 56:136-9. 2002
  23. pmc Diabetes mellitus as a risk factor for gastrointestinal cancer among American veterans
    M Mazen Jamal
    Division of Gastroenterology, Veterans Affairs VA Medical Center, 5901 E 7th St Long Beach, CA 90822, United States
    World J Gastroenterol 15:5274-8. 2009
    ..To assess the risk of biliary and pancreatic cancers in a large cohort of patients with type 2 diabetes mellitus (DM)...
  24. doi request reprint EUS-guided portal pressure gradient measurement with a novel 25-gauge needle device versus standard transjugular approach: a comparison animal study
    Jason Y Huang
    H H Chao Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, Orange, California, USA
    Gastrointest Endosc 84:358-62. 2016
    ..The aim of this study was to develop a novel EUS-guided system using a 25G FNA needle and compact manometer to directly measure PPG and to evaluate its performance and clinical feasibility...
  25. doi request reprint EUS-guided in vivo imaging of the porcine esophageal enteric nervous system by using needle-based confocal laser endomicroscopy
    Jason B Samarasena
    Division of Gastroenterology and Hepatology, Department of Medicine, University of California Irvine, Orange, California, USA
    Gastrointest Endosc 82:1116-20. 2015
    ....
  26. doi request reprint In vivo identification of pancreatic cystic neoplasms with needle-based confocal laser endomicroscopy
    Takeshi Tsujino
    H H Chao Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, United States
    Best Pract Res Clin Gastroenterol 29:601-10. 2015
    ..Needle-based CLE during EUS has recently been examined to evaluate PLCs, and the specific criteria of nCLE for the diagnosis of PLCs have been proposed...
  27. ncbi request reprint An early comparison between endoscopic ultrasound-guided fine-needle aspiration and mediastinoscopy for diagnosis of mediastinal malignancy
    D L Serna
    Department of Surgery Cardiothoracic, University of California, Irvine Medical Center, Orange 92668, USA
    Am Surg 64:1014-8. 1998
    ..Mediastinoscopy and EUS/FNA target different areas of the mediastinum and may be complimentary in the evaluation of mediastinal malignancy and staging of bronchogenic carcinoma...
  28. doi request reprint The PEG-Pedi-PEG technique: a novel method for percutaneous endoscopic gastrojejunostomy tube placement (with video)
    Jason B Samarasena
    Division of Gastroenterology and Hepatology, University of California Irvine, Orange, California, USA
    Gastrointest Endosc 84:1030-1033. 2016
    ..The aim of this study was to evaluate the feasibility and safety of a novel technique that creates PEG-J tubes by combining an adult percutaneous gastrostomy (PEG) tube with a pediatric PEG tube, the PEG-Pedi-PEG procedure...
  29. pmc EUS compared with endoscopy plus transabdominal US in the initial diagnostic evaluation of patients with upper abdominal pain
    Kenneth J Chang
    Division of Gastroenterology, Department of Medicine, H H Chao Comprehensive Digestive Disease Center, University of California, Irvine, Orange, California, USA
    Gastrointest Endosc 72:967-74. 2010
    ..Primary upper endoscopy (EGD) and transabdominal US (TUS) are often performed in patients with upper abdominal pain...
  30. ncbi request reprint Endoscopic palliation of pancreatic adenocarcinoma
    Wichit Srikureja
    Division of Gastroenterology, University of California Irvine, Orange, California, USA
    Curr Opin Gastroenterol 21:601-5. 2005
    ..Novel and emerging endoscopic approaches are also briefly discussed...
  31. ncbi request reprint Optimal methods for staging rectal cancer
    V Raman Muthusamy
    H H Chao Comprehensive Digestive Disease Center, Chao Family Comprehensive Cancer Center, Department of Medicine, University of California, Irvine Medical Center, Orange, CA 92868, USA
    Clin Cancer Res 13:6877s-84s. 2007
    ..This article reviews the current literature about the staging accuracy of the various modalities and suggests a staging algorithm for rectal cancer...
  32. ncbi request reprint A resource utilization projection study of EUS
    Koy Srirojanakul Parada
    Division of Gastroenterology, Medical Center, University of California Irvine, Orange, CA 92868, USA
    Gastrointest Endosc 55:328-34. 2002
    ..Whether currently available resources are sufficient to meet the potential need for EUS is uncertain. This study examines the hypothetical demand for EUS in the United States...
  33. doi request reprint Minimally invasive esophagectomy: lessons learned from 104 operations
    Ninh T Nguyen
    Department of Surgery, University of California, Irvine Medical Center, Orange, CA 92868, USA
    Ann Surg 248:1081-91. 2008
    ..To review the outcomes of 104 consecutive minimally invasive esophagectomy (MIE) procedures for the treatment of benign and malignant esophageal disease...
  34. ncbi request reprint Endoscopic ultrasound-guided fine-needle aspiration biopsy in esophageal cancer
    J Klapman
    Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, Orange, California 92868 3298, USA
    Endoscopy 37:381-5. 2005
  35. ncbi request reprint Maximizing the yield of EUS-guided fine-needle aspiration
    Kenneth J Chang
    Gastrointestinal Oncology and Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, Orange, California, USA
    Gastrointest Endosc 56:S28-34. 2002
  36. ncbi request reprint Reduced expression of epidermal growth factor receptor-related protein in hepatocellular carcinoma: implications for cancer growth
    Woo Sung Moon
    Department of Medicine, VA Medical Center, Long Beach and The University of California, Irvine, CA 90822 5201, USA
    Digestion 69:219-24. 2004
    ..The recently cloned EGFR-related protein (ERRP) has been proposed to be a negative regulator of EGFR. The expression of ERRP in non-malignant liver cells and in HCC, and its relation to cell proliferation, have not been examined...
  37. ncbi request reprint EUS in the detection of ascites and EUS-guided paracentesis
    P T Nguyen
    Division of Gastroenterology, University of California, Irvine Medical Center, Orange, USA
    Gastrointest Endosc 54:336-9. 2001
    ..EUS-guided paracentesis appears to be safe and effective and can identify malignant ascites...
  38. ncbi request reprint Negative predictive value of endoscopic ultrasound in a large series of patients with a clinical suspicion of pancreatic cancer
    Jason B Klapman
    Division of Gastrointestinal Tumors, Section of Endoscopic Oncology, H Lee Moffitt Center and Research Institute, Tampa, Florida 33612, USA
    Am J Gastroenterol 100:2658-61. 2005
    ..Our aim was to determine the negative predictive value (NPV) of EUS in patients with a suspicion of pancreatic cancer...
  39. doi request reprint Circumferential ablation of Barrett's esophagus that contains high-grade dysplasia: a U.S. Multicenter Registry
    Robert A Ganz
    Minnesota Gastroenterology, Plymouth, Minnesota 55446, USA
    Gastrointest Endosc 68:35-40. 2008
    ..The management strategies for Barrett's esophagus (BE) that contains high-grade dysplasia (HGD) include intensive endoscopic surveillance, photodynamic therapy, thermal ablation, EMR, and esophagectomy...
  40. ncbi request reprint EUS-guided FNA: the training is moving
    Kenneth J Chang
    Gastrointest Endosc 59:69-73. 2004
  41. ncbi request reprint Acute pancreatitis after EUS-guided FNA of solid pancreatic masses: a pooled analysis from EUS centers in the United States
    Mohamad A Eloubeidi
    Endoscopic Ultrasound Program, University of Alabama, 1530 3rd Avenue South, ZRB 636, Birmingham, AL 35294 0007, USA
    Gastrointest Endosc 60:385-9. 2004
    ..The aim of this study was to determine the frequency and the severity of pancreatitis after EUS-guided FNA of solid pancreatic masses. A survey of centers that offer training in EUS in the United States was conducted...
  42. ncbi request reprint Risk factors for pancreatic cancer and early diagnosis of pancreatic cancer
    Kenji Yamao
    Department of Gastroenterology, Aichi Cancer Center Hospital
    Nihon Shokakibyo Gakkai Zasshi 105:8-16. 2008
  43. ncbi request reprint Balloon-based, circumferential, endoscopic radiofrequency ablation of Barrett's esophagus: 1-year follow-up of 100 patients
    Virender K Sharma
    Division of Gastroenterology and Hepatology, Mayo Clinic Scottsdale Phoenix, Scottsdale, Arizona, USA
    Gastrointest Endosc 65:185-95. 2007
    ..To assess the dose-response, safety, and efficacy of circumferential endoscopic ablation of Barrett's esophagus (BE) by using an endoscopic balloon-based ablation device (HALO360 System)...