Affiliation: University of Connecticut Health Center
- Genomewide characterization of non-polyadenylated RNAsLi Yang
Department of Genetics and Developmental Biology, University of Connecticut Stem Cell Institute, University of Connecticut Health Center, 263 Farmington Ave, Farmington, CT 06030 6403, USA
Genome Biol 12:R16. 2011..Current deep sequencing approaches largely depend on the enrichment of transcripts with a poly(A) tail, and therefore offer little insight into the nature and expression of transcripts that lack poly(A) tails...
- SINEs point to abundant editing in the human genomeJoshua DeCerbo
Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, CT 06030 3301, USA
Genome Biol 6:216. 2005..Most of this editing is in Alu element transcripts, which are unique to primates. This editing might have no function or might be involved in functions such as the regulation of splicing, chromatin or nuclear localization of transcripts...
- Decoding the function of nuclear long non-coding RNAsLing Ling Chen
Department of Genetics and Developmental Biology, University of Connecticut Stem Cell Institute, Farmington, CT 06030 3301, USA
Curr Opin Cell Biol 22:357-64. 2010..In this review, we highlight some recent progress in how lncRNAs regulate these important nuclear processes at the molecular level...
- Molecular basis for an attenuated cytoplasmic dsRNA response in human embryonic stem cellsLing Ling Chen
Department of Genetics and Developmental Biology, University of Connecticut Stem Cell Institute, Farmington, CT, USA
Cell Cycle 9:3552-64. 2010....
- The Fate of dsRNA in the NucleusGordon Carmichael; Fiscal Year: 2006..Such studies might shed light on vital and conserved functions for these proteins. For each organism, we will study the I-RNA binding protein and its molecular partners. ..