Saundra S Buys
Affiliation: University of Utah
- The Breast Cancer Family Registry: an infrastructure for cooperative multinational, interdisciplinary and translational studies of the genetic epidemiology of breast cancerEsther M John
Clinical and Genetic Epidemiology Research Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland, USA
Breast Cancer Res 6:R375-89. 2004....
- Ovarian cancer screening in the Prostate, Lung, Colorectal and Ovarian (PLCO) cancer screening trial: findings from the initial screen of a randomized trialSaundra S Buys
Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112 5550, USA
Am J Obstet Gynecol 193:1630-9. 2005..Ovarian cancer screening with transvaginal ultrasound (TVU) and CA-125 was evaluated in the Prostate, Lung, Colorectal and Ovarian (PLCO) Trial...
- Professional opportunities and responsibilities in the provision of genetic information to children relinquished for adoptionVickie L Venne
Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA
Am J Med Genet A 119:41-6. 2003..This article briefly describes the experience and discusses the unique issues that arise in counseling a parent who has relinquished a child who is subsequently at risk to inherit a mutation for an adult onset genetic condition...
- Medical management of skeletal metastasisMargaret K Yu
Division of Medical Oncology, Department of Internal Medicine, University of Utah School of Medicine, 2000 Circle of Hope, Room 3344, Salt Lake City, UT 84112, USA
Neurosurg Clin N Am 15:529-36, xi. 2004....
- Effect of screening on ovarian cancer mortality: the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Randomized Controlled TrialSaundra S Buys
Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, USA
JAMA 305:2295-303. 2011..Screening for ovarian cancer with cancer antigen 125 (CA-125) and transvaginal ultrasound has an unknown effect on mortality...
- Effects of BRCA1 and BRCA2 mutations on female fertilityKen R Smith
Department of Family and Consumer Studies, University of Utah, 225 South 1400 East Alfred Emery Building 228, Salt Lake City, UT 84112, USA
Proc Biol Sci 279:1389-95. 2012..Our findings suggest the need to re-examine the wider role played by BRCA1/2 mutations. Elevated fertility of female mutation carriers indicates that they are more fecund despite their elevated post-reproductive mortality risks...
- Clinical experience with the NCCN distress thermometer in breast cancer patientsMichele Dabrowski
University Hospital Behavioral Health Department, Huntsman Cancer Hospital Patient, Family Support Services, 2000 Circle of Hope, Salt Lake City, UT 84112, USA
J Natl Compr Canc Netw 5:104-11. 2007..In our experience, the tool promoted communication between the patient and the health care team, which enhanced treating psychosocial and physical symptoms. Methods to optimize the use of this screen are proposed...
- The epidemiology of CA-125 in women without evidence of ovarian cancer in the Prostate, Lung, Colorectal and Ovarian Cancer (PLCO) Screening TrialChristine C Johnson
Josephine Ford Cancer Center, Henry Ford Hospital, Detroit, MI, USA
Gynecol Oncol 110:383-9. 2008..To determine the epidemiology of CA-125 in women without ovarian cancer...
- Ovarian cancer screening in women with a family history of breast or ovarian cancerJames V Lacey
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
Obstet Gynecol 108:1176-84. 2006..To evaluate positive predictive values of CA 125 or transvaginal ultrasonography screening for ovarian cancer according to family history of breast or ovarian cancer...
- A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancerDavid J Hunter
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Nat Genet 39:870-4. 2007..Our summary results from the GWAS are available online in a form that should speed the identification of additional risk loci...
- Reduced mammographic density with use of a gonadotropin-releasing hormone agonist-based chemoprevention regimen in BRCA1 carriersJeffrey N Weitzel
Department of Clinical Cancer Genetics, City of Hope Cancer Center, 1500 East Duarte Road, Duarte, CA 91010, USA
Clin Cancer Res 13:654-8. 2007..We evaluated the efficacy, safety, and tolerability of hormonal chemoprevention with a gonadotropin-releasing hormone agonist (GnRHA) with low-dose add-back steroids in BRCA1(mut) carriers...
- BRCA2 mutation-associated breast cancers exhibit a distinguishing phenotype based on morphology and molecular profiles from tissue microarraysAnita L Bane
Department of Pathology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, 600 University Avenue, Toronto, Ontario, Canada
Am J Surg Pathol 31:121-8. 2007....
- BRCA1 and BRCA2 mutation carriers, oral contraceptive use, and breast cancer before age 50Robert W Haile
Department of Preventive Medicine, University of Southern California Keck School of Medicine, 1441 Eastlake Avenue, MS 9175, Los Angeles, CA 90089 9175, USA
Cancer Epidemiol Biomarkers Prev 15:1863-70. 2006..Understanding the effect of oral contraceptives on risk of breast cancer in BRCA1 or BRCA2 mutation carriers is important because oral contraceptive use is a common, modifiable practice...
- Ovarian volume: determinants and associations with cancer among postmenopausal womenMark E Sherman
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 15:1550-4. 2006..Confirmation of these findings in future studies, including analyses of serum hormone levels and tissues, may provide insights into hormonal carcinogenesis among older women...
- Classification and risk stratification of invasive breast carcinomas using a real-time quantitative RT-PCR assayLaurent Perreard
The ARUP Institute for Clinical and Experimental Pathology, SLC, Utah, USA
Breast Cancer Res 8:R23. 2006..In the current article, we use microarray analysis and a real-time quantitative reverse-transcription (qRT)-PCR assay to risk-stratify breast cancers based on biological 'intrinsic' subtypes and proliferation...
- Folate intake, alcohol use, and postmenopausal breast cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening TrialRachael Z Stolzenberg-Solomon
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Suite 320, Rockville, MD 20852, USA
Am J Clin Nutr 83:895-904. 2006..Several epidemiologic studies suggest that higher folate intakes are associated with lower breast cancer risk, particularly in women with moderate alcohol consumption...
- Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage ConsortiumDeborah Thompson
CRC Genetic Epidemiology Unit, Strangeways Research Laboratories, University of Cambridge, Cambridge CB1 4RN, United Kingdom
Proc Natl Acad Sci U S A 99:827-31. 2002..65 was -11.0]. We conclude that, if a susceptibility gene does exist at this locus, it can only account for a small proportion of non-BRCA1/2 families with multiple cases of early-onset breast cancer...