K O Bushara
Affiliation: University of Minnesota
- Neural correlates of cross-modal bindingKhalafalla O Bushara
Neurology Service, Room 4B135, Minneapolis Veterans Affairs Medical Center, One Veterans Drive, Minneapolis, Minnesota 55417, USA
Nat Neurosci 6:190-5. 2003..This activation pattern suggests that a reciprocal and 'competitive' interaction between multimodal and unimodal areas underlies the perceptual interpretation of simultaneous signals from multiple sensory modalities...
- Clinical characteristics of patients with spinocerebellar ataxias 1, 2, 3 and 6 in the US; a prospective observational studyTetsuo Ashizawa
Department of Neurology and McKnight Brain Institute, University of Florida, 1149 S, Newell Dr, L3 100, Gainesville, FL 32611, USA
Orphanet J Rare Dis 8:177. 2013..SCA1, 2, 3 and 6 are the four most common SCAs, all caused by expanded polyglutamine-coding CAG repeats. Their pathomechanisms are becoming increasingly clear and well-designed clinical trials will be needed...
- Neurologic presentation of celiac diseaseKhalafalla O Bushara
Neurology Department, Minneapolis VA Medical Center, University of Minnesota, Minneapolis, Minnesota, USA
Gastroenterology 128:S92-7. 2005..Further studies clearly are needed to assess the efficacy of gluten-free diet and to address the underlying mechanisms of nervous system pathology in gluten sensitivity...
- The effect of levetiracetam on essential tremorKhalafalla O Bushara
Neurology Service 127, Minneapolis Veterans Affairs Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA
Neurology 64:1078-80. 2005..There was a significant reduction of hand tremor for at least 2 hours as measured by accelerometry and functional tests...
- Antigliadin antibodies in Huntington's diseaseKhalafalla O Bushara
Department of Neurology, University of Minnesota, Minneapolis, USA
Neurology 62:132-3. 2004....
- Pilot trial of 1-octanol in essential tremorK O Bushara
Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA
Neurology 62:122-4. 2004..1-Octanol significantly decreased tremor amplitude for up to 90 minutes. The results suggest 1-octanol as a well-tolerated and safe potential treatment for ET. Further trials are warranted...
- Neural correlates of auditory-visual stimulus onset asynchrony detectionK O Bushara
National Institute of Neurological Disorders and Stroke, Human Motor Control Section, and Cognitive Neuroscience Section, National Institutes of Health, Bethesda, Maryland 20892-1428, USA
J Neurosci 21:300-4. 2001....
- Open-label dose-escalation study of oral 1-octanol in patients with essential tremorH A Shill
Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892 1428, USA
Neurology 62:2320-2. 2004..No overt intoxication was seen. There was evidence for efficacy, with a significant reduction in tremor amplitude as measured by accelerometry and handwriting that was maximal at 2 hours. Higher doses may produce more sustained benefit...
- Gluten sensitivity in sporadic and hereditary cerebellar ataxiaK O Bushara
Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892-1428, USA
Ann Neurol 49:540-3. 2001..Patients with hereditary ataxia (including asymptomatic patients with known ataxia genotype) should be considered for screening for gluten sensitivity and gluten-free diet trials...
- Multiple tactile maps in the human cerebellumK O Bushara
Department of Neurology, University of Wisconsin, Minneapolis Veterans Affairs Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA
Neuroreport 12:2483-6. 2001..in agreement with previous functional imaging studies, our results show a large-scale, between-limb somatotopy comparable to that shown in early animal studies...
- Anti-ganglioside antibodies in idiopathic and hereditary cerebellar degenerationHolly A Shill
Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1428, USA
Neurology 60:1672-3. 2003..The authors investigated the presence of antiganglioside antibodies in 22 patients with hereditary and nonhereditary ataxia and found 64% reactive in a novel agglutination test...
- Role of the olivo-cerebellar system in timingDuo Xu
Neurology Service, Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
J Neurosci 26:5990-5. 2006..Our results suggest that the primary role of the inferior olive and the climbing fiber system in timing is the encoding of temporal information independent of motor behavior...
- Constraint-induced therapy in stroke: magnetic-stimulation motor maps and cerebral activationGeorge F Wittenberg
Human Cortical Physiology Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA
Neurorehabil Neural Repair 17:48-57. 2003..Both changes may reflect improved ability of upper motor neurons to produce movement...
- Immune cross-reactivity in celiac disease: anti-gliadin antibodies bind to neuronal synapsin IArmin Alaedini
Department of Neurology and Neuroscience, Cornell University, and St Vincent s Hospital Manhattan, New York, NY 10021, USA
J Immunol 178:6590-5. 2007..Anti-gliadin Abs from patients with celiac disease also bound to the protein. Such cross-reactivity may provide clues into the pathogenic mechanism of the neurologic deficits that are associated with gluten sensitivity...