M P Brown

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi request reprint Exercise and injury increase chondroitin sulfate chain length and decrease hyaluronan chain length in synovial fluid
    M P Brown
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610 1432, USA
    Osteoarthritis Cartilage 15:1318-25. 2007
  2. ncbi request reprint Joint dependent concentrations of bone alkaline phosphatase in serum and synovial fluids of horses with osteochondral injury: an analytical and clinical validation
    T N Trumble
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610 1432, USA
    Osteoarthritis Cartilage 16:779-86. 2008
  3. ncbi request reprint A simplified method of determining synovial fluid chondroitin sulfate chain length
    M P Brown
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610 1432, USA
    Osteoarthritis Cartilage 15:1443-5. 2007
  4. pmc Pharmacokinetics of orbifloxacin and its concentration in body fluids and in endometrial tissues of mares
    G R Haines
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610-0136, USA
    Can J Vet Res 65:181-7. 2001
  5. ncbi request reprint Pharmacokinetics of azithromycin and concentration in body fluids and bronchoalveolar cells in foals
    S Jacks
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610-0136, USA
    Am J Vet Res 62:1870-5. 2001
  6. doi request reprint Osteochondral injury increases type II collagen degradation products (C2C) in synovial fluid of Thoroughbred racehorses
    T N Trumble
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610 0136, USA
    Osteoarthritis Cartilage 17:371-4. 2009
  7. ncbi request reprint Probenecid infusion in mares: effect on para-aminohippuric acid clearance
    R Gronwall
    Department of Medical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610
    Am J Vet Res 49:250-3. 1988
  8. ncbi request reprint Pharmacokinetics of sodium cephapirin in lactating dairy cows
    M Prades
    Department of Surgical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610 0116
    Am J Vet Res 49:1888-90. 1988
  9. ncbi request reprint Continuous measurement of caffeine and two metabolites in blood and skeletal muscle of unrestrained adult horses by semi-automated in vivo microdialysis
    C C Chou
    Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610-0144, USA
    J Vet Pharmacol Ther 24:405-14. 2001
  10. ncbi request reprint Pharmacokinetics and synovial fluid concentrations of cephapirin in calves with suppurative arthritis
    M P Brown
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610 0136
    Am J Vet Res 52:1438-40. 1991

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Exercise and injury increase chondroitin sulfate chain length and decrease hyaluronan chain length in synovial fluid
    M P Brown
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610 1432, USA
    Osteoarthritis Cartilage 15:1318-25. 2007
    ....
  2. ncbi request reprint Joint dependent concentrations of bone alkaline phosphatase in serum and synovial fluids of horses with osteochondral injury: an analytical and clinical validation
    T N Trumble
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610 1432, USA
    Osteoarthritis Cartilage 16:779-86. 2008
    ....
  3. ncbi request reprint A simplified method of determining synovial fluid chondroitin sulfate chain length
    M P Brown
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610 1432, USA
    Osteoarthritis Cartilage 15:1443-5. 2007
    ....
  4. pmc Pharmacokinetics of orbifloxacin and its concentration in body fluids and in endometrial tissues of mares
    G R Haines
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610-0136, USA
    Can J Vet Res 65:181-7. 2001
    ..At a dosage of 7.5 mg/kg once a day, many gram-negative pathogens, such as Actinobacillus equuli, Escherichia coli, Pasteurella spp., and Salmonella spp. would be expected to be susceptible to orbifloxacin...
  5. ncbi request reprint Pharmacokinetics of azithromycin and concentration in body fluids and bronchoalveolar cells in foals
    S Jacks
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610-0136, USA
    Am J Vet Res 62:1870-5. 2001
    ..Persistence of high azithromycin concentrations in PELF and bronchoalveolar cells 48 hours after discontinuation of administration suggests that after 5 daily doses, oral administration at 48-hour intervals may be adequate...
  6. doi request reprint Osteochondral injury increases type II collagen degradation products (C2C) in synovial fluid of Thoroughbred racehorses
    T N Trumble
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610 0136, USA
    Osteoarthritis Cartilage 17:371-4. 2009
    ....
  7. ncbi request reprint Probenecid infusion in mares: effect on para-aminohippuric acid clearance
    R Gronwall
    Department of Medical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610
    Am J Vet Res 49:250-3. 1988
    ..Bioavailability of probenecid was 117 and 102% for 2 mares after a single intragastric dose, compared with a single IV dose...
  8. ncbi request reprint Pharmacokinetics of sodium cephapirin in lactating dairy cows
    M Prades
    Department of Surgical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610 0116
    Am J Vet Res 49:1888-90. 1988
    ..18 microgram/ml at PIH 4. Cephapirin was not detected in the endometrium. The highest concentration of cephapirin in urine was 452 micrograms/ml, 2 hours after the 4th dose (PIH 26)...
  9. ncbi request reprint Continuous measurement of caffeine and two metabolites in blood and skeletal muscle of unrestrained adult horses by semi-automated in vivo microdialysis
    C C Chou
    Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610-0144, USA
    J Vet Pharmacol Ther 24:405-14. 2001
    ..This study demonstrates that our novel semi-automated microdialysis procedure for continuous monitoring of drug and metabolite levels may be useful for related studies in other domesticated large animal species...
  10. ncbi request reprint Pharmacokinetics and synovial fluid concentrations of cephapirin in calves with suppurative arthritis
    M P Brown
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610 0136
    Am J Vet Res 52:1438-40. 1991
    ..04 +/- 0.612 micrograms/ml) was not significantly different from that in suppurative synovial fluid (0.88 +/- 0.495 micrograms/ml; P greater than 0.05). Elimination half-life was 0.60 hours and clearance was 1,593 ml/h/kg...
  11. doi request reprint Vascular perfusion of the dorsal and palmar condyles of the equine third metacarpal bone
    M T Alber
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, USA
    Equine Vet J 46:370-4. 2014
    ..Palmar osteochondral disease (POD) is an overload arthrosis that commonly affects fetlock joints of racing Thoroughbreds (TB) but the aetiopathogenesis of the disease has not been well defined...
  12. ncbi request reprint Capillary zone electrophoresis for the determination of atovaquone in serum
    C C Chou
    Department of Large Animal and Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610, USA
    J Chromatogr B Biomed Sci Appl 742:441-5. 2000
    ..Replacement of acetonitrile with 75 mM surfactant 3-(dimethyldodecylammonio)propanesulfonate gave similar sensitivity and provided an additional option to facilitate the separation of atovaquone on multiple-drug samples...
  13. doi request reprint Removal of O-linked and N-linked oligosaccharides is required for optimum detection of NITEGE neoepitope on ADAMTS4-digested fetal aggrecans: implications for specific N-linked glycan-dependent aggrecanolysis at Glu373-Ala374
    J E Frank
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610 0136, USA
    Osteoarthritis Cartilage 17:777-81. 2009
    ..Our objective was to determine whether enzymatic removal of O- and/or N-linked oligosaccharides from the fetal products would enable detection of the NITEGE neoepitope with anti-NITEGE antibody...
  14. ncbi request reprint Disposition of oral clarithromycin in foals
    S Jacks
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    J Vet Pharmacol Ther 25:359-62. 2002
    ..Based on the pharmacokinetic parameters, the MIC90 of R. equi isolates, and predicted steady state concentrations, an oral dose of 7.5 mg/kg given every 12 hours would appear appropriate for the treatment of R. equi infections in foals...
  15. ncbi request reprint Influence of starch intake on growth and skeletal development of weanling horses
    E A Ott
    Department of Animal Sciences, University of Florida, Gainesville, 32611 0910, USA
    J Anim Sci 83:1033-43. 2005
    ..Bone osteochondrotic lesions were not related to the diet and were found to decrease during the course of the experiment for both the high-starch and the medium-starch diets (P = 0.006 and 0.016, respectively)...
  16. ncbi request reprint Examination of synovial fluid and serum following intravenous injections of hyaluronan for the treatment of osteoarthritis in dogs
    S O Canapp
    Department of Orthopedic Surgery and Sports Medicine, VCA Veterinary Referral Associates, Gaithersburg, Maryland 20878, USA
    Vet Comp Orthop Traumatol 18:169-74. 2005
    ..Stifles with cranial cruciate ligament insufficiency had significant alterations in SF viscosity and HA concentrations...