Affiliation: University of California
- The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting stepChristopher Esk
Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA
J Cell Biol 188:131-44. 2010..Like CHC22, syntaxin 10 is not expressed in mice but is present in humans and other vertebrates, implicating two species-restricted endosomal traffic proteins in GLUT4 transport...
- Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOGAmy B Foraker
Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA 94143, USA
J Cell Biol 198:591-605. 2012..Therefore, we propose that clathrin promotes centrosome maturation by stabilizing the microtubule-binding protein ch-TOG, defining a novel role for the clathrin-ch-TOG-TACC3 complex...
- The CHC22 clathrin-GLUT4 transport pathway contributes to skeletal muscle regenerationSachiko Hoshino
The G W Hooper Foundation, Departments of Bioengineering and Therapeutic Sciences, Pharmaceutical Chemistry, and Microbiology and Immunology, University of California San Francisco, San Francisco, California, United States of America Department of Neurology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
PLoS ONE 8:e77787. 2013..Extrapolating these findings, CHC22 and GLUT4 can be considered markers of muscle regeneration in humans. ..
- Diversity of clathrin function: new tricks for an old proteinFrances M Brodsky
Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California 94143 0552, USA
Annu Rev Cell Dev Biol 28:309-36. 2012..By considering these diverse clathrin functions, along with intracellular sorting roles and influences on mitosis, further relevance of clathrin function to human health and disease is established...
- Evolutionary cell biology: Lessons from diversityFrances M Brodsky
University of California, San Francisco, California 94143, USA
Nat Cell Biol 14:651. 2012..Novel perspectives emerge from a recent conference on the origins of eukaryotic cells, which covered phylogenetics, population genetics and evolutionary consequences of energy requirements and host–pathogen interactions...
- Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cellsDun Yang
G W Hooper Foundation and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143 0552, USA
Proc Natl Acad Sci U S A 99:9942-7. 2002..esiRNA works by eliciting the destruction of its cognate mRNA. Because of its simplicity and potency, this approach is useful for analysis of mammalian gene functions...
- Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domainJeremy D Wilbur
Graduate Program in Biophysics, University of California, San Francisco, California 94143, USA
Acta Crystallogr D Biol Crystallogr 66:314-8. 2010..A hydrogen-bond network and changes in coiled-coil monomer interaction suggest that the HIP1 coiled-coil domain is uniquely suited to allow conformational flexibility...
- STRUCTURAL BASIS FOR CLATHRIN FUNCTIONFRANCES BRODSKY; Fiscal Year: 2002..abstract_text> ..