Elizabeth A Braunlin
Affiliation: University of Minnesota
- Unexpected coronary artery findings in mucopolysaccharidosis. Report of four cases and literature reviewElizabeth Braunlin
Department of Pediatrics, University of Minnesota Medical School Electronic address
Cardiovasc Pathol 23:145-51. 2014..Given the rarity of these conditions, autopsy specimens are uncommon...
- Usefulness of bone marrow transplantation in the Hurler syndromeElizabeth A Braunlin
University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
Am J Cardiol 92:882-6. 2003..Cardiac ultrasound findings of patients with this syndrome >10 years after successful bone marrow transplantation are described...
- Cardiac functional and histopathologic findings in humans and mice with mucopolysaccharidosis type I: implications for assessment of therapeutic interventions in hurler syndromeElizabeth Braunlin
Department of Pediatrics, University of Minnesota, Minneapolis 55455, USA
Pediatr Res 59:27-32. 2006....
- Cardiac findings after enzyme replacement therapy for mucopolysaccharidosis type IElizabeth A Braunlin
Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota, USA
Am J Cardiol 98:416-8. 2006..In conclusion, long-term enzyme replacement therapy has some clear benefits for the myocardium, but the cardiac valves appear unresponsive, and the ultimate effect on the coronary vasculature is unknown...
- Cardiac disease in patients with mucopolysaccharidosis: presentation, diagnosis and managementElizabeth A Braunlin
Pediatric Cardiology, University of Minnesota, Minneapolis, MN 55455, USA
J Inherit Metab Dis 34:1183-97. 2011..Cardiac valve disease is usually unresponsive or, at best, stabilized, although ERT within the first few months of life may prevent valve involvement, a fact that emphasizes the importance of early diagnosis and treatment in MPS...
- Clear cells in the atrioventricular valves of infants with severe human mucopolysaccharidosis (Hurler syndrome) are activated valvular interstitial cellsElizabeth Braunlin
Department of Pediatrics, University of Minnesota Hospital Fairview, Minneapolis, MN 55455, USA
Cardiovasc Pathol 20:315-21. 2011..We hypothesized that the "clear" or "Hurler" cells within the atrioventricular valves from individuals with untreated mucopolysaccharidosis type I are activated valvular interstitial cells...
- Gender-related dimorphism in aortic insufficiency in murine mucopolysaccharidosis type IJakub Tolar
Divisions of Hematology, Oncology, Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA
J Heart Valve Dis 18:524-9. 2009....
- The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemiaJakub Tolar
Cancer Center and Department of Pediatrics, Division of Hematology Oncology, Blood and Marrow Transplantation, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455, USA
Exp Hematol 35:682-90. 2007..Multipotent adult progenitor cells (MAPCs) are adult stem cells derived from bone marrow. We investigated the capacity of MAPCs to aid in tissue healing after myocardial ischemia in mice with different levels of immune competence...
- Angiotensin receptor blockade mediated amelioration of mucopolysaccharidosis type I cardiac and craniofacial pathologyMark J Osborn
Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota, 420 Delaware St SE, MMC 366, Minneapolis, MN, 55455, USA
J Inherit Metab Dis . 2016..These data show a key role for the RAS in MPS associated pathology and support the inclusion of losartan as an augmentation to current therapies...
- Troponin I levels in a hemolytic uremic syndrome patient with severe cardiac failureVarvara Askiti
Division of Nephrology, Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN 55455, USA
Pediatr Nephrol 19:345-8. 2004..1 microg/l), and peaked (140.6 microg/l) at 24 h. It then fell gradually and was normal at discharge. These results suggest that measurement of cTnI may be a useful predictor of cardiac involvement in severely affected children with HUS...