Michelle A Booden

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformation
    Michelle A Booden
    Department of Pharmacology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Mol Cell Biol 22:2487-97. 2002
  2. pmc Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA
    Michelle A Booden
    Department of Pharmacology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, 27599, USA
    Mol Cell Biol 22:4053-61. 2002
  3. ncbi Critical role of the pleckstrin homology domain in Dbs signaling and growth regulation
    Ernesto J Fuentes
    Department of Biochemistry and Biophysics, University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina 27599, USA
    J Biol Chem 278:21188-96. 2003
  4. pmc Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasion
    Michelle A Booden
    Department of Pharmacology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7295, USA
    Mol Cell Biol 24:1990-9. 2004
  5. pmc The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis
    Patrick Kelly
    Department Pharmacology, Duke University Medical Center, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 103:8173-8. 2006

Collaborators

Detail Information

Publications5

  1. pmc Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformation
    Michelle A Booden
    Department of Pharmacology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Mol Cell Biol 22:2487-97. 2002
    ..In conclusion, the PH domain and CRD are mechanistically distinct, positive modulators of Vav2 DH domain function in vivo...
  2. pmc Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA
    Michelle A Booden
    Department of Pharmacology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, 27599, USA
    Mol Cell Biol 22:4053-61. 2002
    ..Our findings suggest that the RhoA exchange factor LARG, unlike the related p115 RhoGEF and PDZ-RhoGEF proteins, can serve as an effector for Gq-coupled receptors, mediating their functional linkage to RhoA-dependent signaling pathways...
  3. ncbi Critical role of the pleckstrin homology domain in Dbs signaling and growth regulation
    Ernesto J Fuentes
    Department of Biochemistry and Biophysics, University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina 27599, USA
    J Biol Chem 278:21188-96. 2003
    ....
  4. pmc Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasion
    Michelle A Booden
    Department of Pharmacology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7295, USA
    Mol Cell Biol 24:1990-9. 2004
    ..Thus, our results reveal that a novel alteration in trafficking of activated PAR1 causes persistent signaling and, in addition to other processes and proteins, contributes to breast carcinoma cell invasion...
  5. pmc The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis
    Patrick Kelly
    Department Pharmacology, Duke University Medical Center, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 103:8173-8. 2006
    ....