W E Bolch

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. doi request reprint ICRP dose coefficients: computational development and current status
    W E Bolch
    University of Florida, Gainesville, FL 32611 6131 USA
    Ann ICRP 45:156-77. 2016
  2. doi request reprint Dosimetric models of the eye and lens of the eye and their use in assessing dose coefficients for ocular exposures
    W E Bolch
    University of Florida, Gainesville, FL, USA
    Ann ICRP 44:91-111. 2015
  3. pmc Guidance on the use of handheld survey meters for radiological triage: time-dependent detector count rates corresponding to 50, 250, and 500 mSV effective dose for adult males and adult females
    Wesley E Bolch
    J Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA
    Health Phys 102:305-25. 2012
  4. ncbi request reprint Influences of parameter uncertainties within the ICRP 66 respiratory tract model: particle deposition
    W E Bolch
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville 32611 8300, USA
    Health Phys 81:378-94. 2001
  5. ncbi request reprint Considerations of marrow cellularity in 3-dimensional dosimetric models of the trabecular skeleton
    Wesley E Bolch
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    J Nucl Med 43:97-108. 2002
  6. pmc Hybrid computational phantoms for medical dose reconstruction
    Wesley Bolch
    Advanced Laboratory for Radiation Dosimetry Studies, Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Radiat Environ Biophys 49:155-68. 2010
  7. doi request reprint MIRD pamphlet No. 21: a generalized schema for radiopharmaceutical dosimetry--standardization of nomenclature
    Wesley E Bolch
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    J Nucl Med 50:477-84. 2009
  8. doi request reprint Further explorations of cellular uptake of radioactivity
    Wesley E Bolch
    University of Florida, Gainesville, Florida, USA
    J Nucl Med 49:869-70. 2008
  9. ncbi request reprint Considerations of anthropometric, tissue volume, and tissue mass scaling for improved patient specificity of skeletal S values
    W E Bolch
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville 32611 8300, USA
    Med Phys 29:1054-70. 2002
  10. ncbi request reprint Skeletal absorbed fractions for electrons in the adult male: considerations of a revised 50-microm definition of the bone endosteum
    W E Bolch
    Advanced Laboratory for Radiation Dosimetry Studies ALRADS, Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Radiat Prot Dosimetry 127:169-73. 2007

Research Grants

Collaborators

Detail Information

Publications78

  1. doi request reprint ICRP dose coefficients: computational development and current status
    W E Bolch
    University of Florida, Gainesville, FL 32611 6131 USA
    Ann ICRP 45:156-77. 2016
    ..Progress towards the development of dose coefficients to members of the general public (adolescents, children, infants and fetuses) are also reviewed. ..
  2. doi request reprint Dosimetric models of the eye and lens of the eye and their use in assessing dose coefficients for ocular exposures
    W E Bolch
    University of Florida, Gainesville, FL, USA
    Ann ICRP 44:91-111. 2015
    ..This article will review the data and models of Annex F with particular emphasis on how these models treat tissue regions thought to be associated with stem cells at risk. ..
  3. pmc Guidance on the use of handheld survey meters for radiological triage: time-dependent detector count rates corresponding to 50, 250, and 500 mSV effective dose for adult males and adult females
    Wesley E Bolch
    J Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA
    Health Phys 102:305-25. 2012
    ..Net count rate data are provided in both tabular and graphical format within a series of eight handbooks available at the CDC website (http://www.bt.cdc.gov/radiation/clinicians/evaluation)...
  4. ncbi request reprint Influences of parameter uncertainties within the ICRP 66 respiratory tract model: particle deposition
    W E Bolch
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville 32611 8300, USA
    Health Phys 81:378-94. 2001
    ..Deposition fractions for particles above 1 microm become very uncertain within the deeper regions of the lungs (bronchiolar and alveolar-interstitial)...
  5. ncbi request reprint Considerations of marrow cellularity in 3-dimensional dosimetric models of the trabecular skeleton
    Wesley E Bolch
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    J Nucl Med 43:97-108. 2002
    ..This study attempts to address this issue by using nuclear magnetic resonance microscopy images of trabecular bone to define 3-dimensional (3D) dosimetric models in which explicit spatial distributions of adipose tissue are introduced...
  6. pmc Hybrid computational phantoms for medical dose reconstruction
    Wesley Bolch
    Advanced Laboratory for Radiation Dosimetry Studies, Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Radiat Environ Biophys 49:155-68. 2010
    ..We close with two brief examples of the use of hybrid phantoms in medical dose reconstruction--diagnostic nuclear medicine for pediatric subjects and interventional fluoroscopy for adult patients...
  7. doi request reprint MIRD pamphlet No. 21: a generalized schema for radiopharmaceutical dosimetry--standardization of nomenclature
    Wesley E Bolch
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    J Nucl Med 50:477-84. 2009
    ....
  8. doi request reprint Further explorations of cellular uptake of radioactivity
    Wesley E Bolch
    University of Florida, Gainesville, Florida, USA
    J Nucl Med 49:869-70. 2008
  9. ncbi request reprint Considerations of anthropometric, tissue volume, and tissue mass scaling for improved patient specificity of skeletal S values
    W E Bolch
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville 32611 8300, USA
    Med Phys 29:1054-70. 2002
    ..However, the study indicates that measurements of the spongiosa volume alone may be sufficient for reasonable patient-specific scaling of S values for the majority of radionuclides of interest in internal-emitter therapy...
  10. ncbi request reprint Skeletal absorbed fractions for electrons in the adult male: considerations of a revised 50-microm definition of the bone endosteum
    W E Bolch
    Advanced Laboratory for Radiation Dosimetry Studies ALRADS, Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Radiat Prot Dosimetry 127:169-73. 2007
    ..A representative data set is given for electron dosimetry in the craniofacial bones of the adult male...
  11. ncbi request reprint A video analysis technique for organ dose assessment in pediatric fluoroscopy: applications to voiding cystourethrograms (VCUG)
    Wesley E Bolch
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    Med Phys 30:667-80. 2003
    ..2 and 1.6, respectively. For the male patient, the mean percent dose contribution from fluoroscopy for all irradiated organs was 71 +/- 12%, while that value for the female patient was 88 +/- 4%...
  12. ncbi request reprint Influences of parameter uncertainties within the ICRP-66 respiratory tract model: particle clearance
    Wesley E Bolch
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Health Phys 84:421-35. 2003
    ..As the particle size approaches 10 microm in size, uncertainties in U(s) within these three thoracic tissue regions approach a factor of 1,000 and are dominated by corresponding uncertainties in particle deposition...
  13. ncbi request reprint Beta-particle dosimetry of the trabecular skeleton using Monte Carlo transport within 3D digital images
    D W Jokisch
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville 32611-8300, USA
    Med Phys 28:1505-18. 2001
    ..The techniques developed in this work may be applied to a variety of skeletal sites, thus allowing for the development of skeletal dosimetry models at all skeletal sites for both males and females and as a function of subject age...
  14. ncbi request reprint Voxel effects within digital images of trabecular bone and their consequences on chord-length distribution measurements
    D A Rajon
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville 32611 8300, USA
    Phys Med Biol 47:1741-59. 2002
    ..The study further suggests that bone and marrow chord-length distributions currently utilized in skeletal dosimetry models are most likely affected by voxel effects that yield values of mean chord length lower than their true values...
  15. ncbi request reprint A hyperboliod representation of the bone-marrow interface within 3D NMR images of trabecular bone: applications to skeletal dosimetry
    D A Rajon
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611, USA
    Phys Med Biol 48:1721-40. 2003
    ..The technique was also applied to a real NMR image of human trabecular bone with a similar demonstration of reductions in dosimetry errors...
  16. ncbi request reprint Chord distributions across 3D digital images of a human thoracic vertebra
    D W Jokisch
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville 32611-8300, USA
    Med Phys 28:1493-504. 2001
    ....
  17. ncbi request reprint Influences of parameter uncertainties within the ICRP-66 respiratory tract model: regional tissue doses for 239PuO2 and 238UO2/238U3O8
    Eduardo B Farfan
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Health Phys 84:436-50. 2003
    ....
  18. ncbi request reprint Marching cube algorithm: review and trilinear interpolation adaptation for image-based dosimetric models
    D A Rajon
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Comput Med Imaging Graph 27:411-35. 2003
    ....
  19. ncbi request reprint Surface area overestimation within three-dimensional digital images and its consequence for skeletal dosimetry
    D A Rajon
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville 32611 8300, USA
    Med Phys 29:682-93. 2002
    ..Alternatively, other methods of defining the bone-marrow interface, such as with a polygonal isosurface, would provide improvements in dosimetry without the need for drastic reductions in image voxel size...
  20. ncbi request reprint Skeletal dosimetry via NMR microscopy: investigations of sample reproducibility and signal source
    P W Patton
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville 32611 8300, USA
    Health Phys 82:316-26. 2002
    ..These studies thus provide encouragement that skeletal dosimetry models of improved patient specificity can be achieved via NMR microscopy in vivo...
  21. ncbi request reprint Image segmentation of trabecular spongiosa by visual inspection of the gradient magnitude
    D A Rajon
    Department of Neurosurgery, University of Florida, Gainesville, FL 32611, USA
    Phys Med Biol 51:4447-67. 2006
    ..Both tests demonstrate the ability of the gradient magnitude technique to retrieve sample volumes or media volume fractions with 1% accuracy at 30 microm voxel size...
  22. ncbi request reprint Tomographic physical phantom of the newborn child with real-time dosimetry I. Methods and techniques for construction
    A K Jones
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    Med Phys 33:3274-82. 2006
    ..Included in this paper are images detailing the construction process, and images of the completed phantom...
  23. ncbi request reprint Tissue-equivalent materials for construction of tomographic dosimetry phantoms in pediatric radiology
    A K Jones
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    Med Phys 30:2072-81. 2003
    ..6% for STES-NB, 3.2% for BTES-NB, and 1.2% for LTES of the doses assigned to reference newborn soft, bone, and lung tissue, respectively...
  24. ncbi request reprint Creation of two tomographic voxel models of paediatric patients in the first year of life
    J C Nipper
    Biomedical Engineering Program, University of Florida, Gainesville 32611 8300, USA
    Phys Med Biol 47:3143-64. 2002
    ..7 to 5.2 for the clavicles and spleen, respectively, to lows of 0.2 to 0.3 for the adrenals and scapulae, respectively...
  25. ncbi request reprint A comparison of newborn stylized and tomographic models for dose assessment in paediatric radiology
    R J Staton
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Phys Med Biol 48:805-20. 2003
    ..This observation is opposite of that seen in comparisons of stylized and tomographic models of the adult...
  26. ncbi request reprint Site-specific variability in trabecular bone dosimetry: considerations of energy loss to cortical bone
    P W Patton
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville 32611 8300, USA
    Med Phys 29:6-14. 2002
    ..For the higher-energy beta spectrum of 90Y, these same corrections can reach 8%, 10%, and 11%, respectively...
  27. ncbi request reprint Influences of parameter uncertainties within the ICRP-66 respiratory tract model: a parameter sensitivity analysis
    Thomas E Huston
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Health Phys 85:553-66. 2003
    ..As a result, future research can focus on improving density functions for those input variables that contribute the most to variability in final dose values...
  28. ncbi request reprint A paired-image radiation transport model for skeletal dosimetry
    Amish P Shah
    Department of Biomedical Engineering, University of Florida, Gainesville, Florida 3261 8300, USA
    J Nucl Med 46:344-53. 2005
    ....
  29. ncbi request reprint Dosimetric effect of source centering and residual plaque for beta-emitting catheter based intravascular brachytherapy sources
    V Sehgal
    Department of Radiation Oncology, University of Florida, Gainesville 32610, USA
    Med Phys 28:2162-71. 2001
    ..The results indicate that dose variations range between -28% to +91% when it is assumed that cardiac motion causes catheter movement during coronary lesion irradiation...
  30. ncbi request reprint Application of imaging-derived parameters to dosimetry of intravascular brachytherapy sources: perturbation effects of residual plaque burden
    Varun Sehgal
    Department of Radiation Oncology, University of Florida, Gainesville 32610 0385, USA
    Med Phys 29:1580-9. 2002
    ..90-1.01, 0.84-1.01, and 0.62-1.01. The results indicate the need for accurate assessment of post-PCI clinical measurements such as minimal lumen diameter and residual plaque burden and incorporation of these values into dose calculations...
  31. ncbi request reprint MOSFET dosimeter depth-dose measurements in heterogeneous tissue-equivalent phantoms at diagnostic x-ray energies
    A K Jones
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    Med Phys 32:3209-13. 2005
    ..It is therefore recommended that the MOSFET dosimeters be oriented with their flat sides facing the beam when they are used at shallow depths or on the surface of either phantoms or patients...
  32. ncbi request reprint Accounting for beta-particle energy loss to cortical bone via paired-image radiation transport (PIRT)
    Amish P Shah
    Department of Biomedical Engineering and Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611, USA
    Med Phys 32:1354-66. 2005
    ....
  33. ncbi request reprint An assessment of bone marrow and bone endosteum dosimetry methods for photon sources
    Choonik Lee
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Phys Med Biol 51:5391-407. 2006
    ....
  34. ncbi request reprint Organ and effective doses in newborns and infants undergoing voiding cystourethrograms (VCUG): a comparison of stylized and tomographic phantoms
    Frank D Pazik
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    Med Phys 34:294-306. 2007
    ..These differences are due in part to a reduced ovary dose in the tomographic phantom for right posterior oblique (RPO) views when compared to those seen in the stylized phantom...
  35. ncbi request reprint Effective dose scaling factors for use with cascade impactor sampling data in tenorm inhalation exposures
    Kwang Pyo Kim
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, 32611 8300, USA
    Health Phys 89:359-74. 2005
    ....
  36. ncbi request reprint A review of US anthropometric reference data (1971-2000) with comparisons to both stylized and tomographic anatomic models
    C Huh
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611, USA
    Phys Med Biol 48:3411-29. 2003
    ....
  37. ncbi request reprint Interactions with 3D isotropic and homogeneous radiation fields: a Monte Carlo simulation algorithm
    D A Rajon
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Comput Methods Programs Biomed 70:167-77. 2003
    ..Both algorithms can be easily adapted to any situation that involves the Monte Carlo simulation of radiation interactions of a fixed object immersed within an isotropic and homogeneous radiation field...
  38. ncbi request reprint Chord-based versus voxel-based methods of electron transport in the skeletal tissues
    Amish P Shah
    Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    Med Phys 32:3151-9. 2005
    ....
  39. ncbi request reprint Absorbed fractions for alpha-particles in tissues of trabecular bone: considerations of marrow cellularity within the ICRP reference male
    Christopher J Watchman
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    J Nucl Med 46:1171-85. 2005
    ..Furthermore, variations in alpha-particle absorbed fraction with marrow cellularity have yet to be fully considered...
  40. ncbi request reprint Influence of particle size distribution on inhalation doses to workers in the Florida phosphate industry
    Kwang Pyo Kim
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Health Phys 91:58-67. 2006
    ..The study thus demonstrates the importance of facility- and area-specific particle solubility data in dose assessments for regulatory compliance and for making decisions regarding worker respiratory protection...
  41. ncbi request reprint Comparisons of point and average organ dose within an anthropomorphic physical phantom and a computational model of the newborn patient
    J B Sessions
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville 32611 8300, USA
    Med Phys 29:1080-9. 2002
    ..19 for the stomach (AP chest exam), and SF(POD) of 1.15 for the urinary bladder (AP abdomen exam)...
  42. ncbi request reprint A comparison of skeletal chord-length distributions in the adult male
    Amish P Shah
    Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Health Phys 89:199-215. 2005
    ....
  43. ncbi request reprint Organ and effective doses in infants undergoing upper gastrointestinal (UGI) fluoroscopic examination
    Robert J Staton
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    Med Phys 34:703-10. 2007
    ..The mean effective dose for newborn UGI examinations was not found to be statistically different from that seen in newborn VCUG examinations...
  44. ncbi request reprint Linear regression model for predicting patient-specific total skeletal spongiosa volume for use in molecular radiotherapy dosimetry
    James M Brindle
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida, USA
    J Nucl Med 47:1875-83. 2006
    ..Consequently, a predictive model of the total skeletal spongiosa volume (TSSV) would be a clinically useful tool for improving patient specificity in skeletal dosimetry...
  45. ncbi request reprint MIRD Pamphlet No 19: absorbed fractions and radionuclide S values for six age-dependent multiregion models of the kidney
    Lionel G Bouchet
    Department of Neurological Surgery, University of Florida, Gainesville, Florida 32611 8300, USA
    J Nucl Med 44:1113-47. 2003
    ..The average absorbed dose to the kidneys predicted by such models can misrepresent local regional doses to specific substructures...
  46. ncbi request reprint A tomographic physical phantom of the newborn child with real-time dosimetry. II. Scaling factors for calculation of mean organ dose in pediatric radiography
    Robert J Staton
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    Med Phys 33:3283-9. 2006
    ..An comprehensive set of SF(POD) values is presented in this article for application in pediatric radiography of newborn patients...
  47. ncbi request reprint Effective dose scaling factors for use with uranium series cascade impactor data: a reassessment using the IMBA code
    Kwang Pyo Kim
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Health Phys 91:331-7. 2006
    ..For linearly increasing distributions, greater than 10% corrections in the effective dose are found irregularly across impactor stage, radionuclide, and solubility class, especially for rather steep (1:5) impactor stage activity ratios...
  48. ncbi request reprint Product yields from irradiated glycylglycine in oxygen-free solutions: Monte Carlo simulations and comparison with experiments
    W E Bolch
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville 32611 8300, USA
    Radiat Environ Biophys 37:157-66. 1998
    ..05 M; these contributions drop to 0.07% and 11%, respectively, at 1.2 M...
  49. ncbi request reprint TENORM aerosols in the Florida phosphate industry--assessment of lung fluid solubility and annual effective dose to workers
    Kwang Pyo Kim
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Radiat Prot Dosimetry 123:41-55. 2007
    ..23 +/- 0.02 mSv at shipping areas. These findings are considerably lower than originally postulated in previous studies where no site-specific information on particle size and lung fluid solubility had been available...
  50. ncbi request reprint Age-dependent organ and effective dose coefficients for external photons: a comparison of stylized and voxel-based paediatric phantoms
    Choonik Lee
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611, USA
    Phys Med Biol 51:4663-88. 2006
    ....
  51. ncbi request reprint Whole-body voxel phantoms of paediatric patients--UF Series B
    Choonik Lee
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611, USA
    Phys Med Biol 51:4649-61. 2006
    ..86 mm x 0.86 mm x 3.0 mm, 0.90 mm x 0.90 mm x 5.0 mm, 1.16 mm x 1.16 mm x 6.0 mm, 0.94 mm x 0.94 mm x 6.00 mm and 1.18 mm x 1.18 mm x 6.72 mm, respectively...
  52. ncbi request reprint CT volumetry of the skeletal tissues
    James M Brindle
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611, USA
    Med Phys 33:3796-803. 2006
    ..This work also provides a foundation for future studies where spongiosa volumes are estimated by various raters in more comprehensive CT data..
  53. ncbi request reprint A revised stylized model of the adult extrathoracic and thoracic airways for use with the ICRP-66 human respiratory tract model
    Eduardo B Farfan
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Health Phys 86:337-52. 2004
    ..At energies <50 keV, values of SAF(thyroid<--ET2) are shown to be orders of magnitude higher than the ICRP 66 default given by SAF(thyroid<--brain)...
  54. pmc Hybrid computational phantoms of the 15-year male and female adolescent: applications to CT organ dosimetry for patients of variable morphometry
    Choonsik Lee
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611, USA
    Med Phys 35:2366-82. 2008
    ..These errors are expected to only further increase as one considers CT organ doses in overweight and obese individuals of the adult patient population, thus emphasizing the advantages of patient-sculptable phantom technology...
  55. ncbi request reprint NURBS-based 3-D anthropomorphic computational phantoms for radiation dosimetry applications
    Choonsik Lee
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Radiat Prot Dosimetry 127:227-32. 2007
    ....
  56. ncbi request reprint Method for estimating skeletal spongiosa volume and active marrow mass in the adult male and adult female
    Jose C Pichardo
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    J Nucl Med 48:1880-8. 2007
    ..This model, based on data from only 20 cadavers, did not account for sex differences in TSSV. This study thus extends this work toward sex-specific models...
  57. ncbi request reprint Adipocyte spatial distributions in bone marrow: implications for skeletal dosimetry models
    Amish P Shah
    Department of Biomedical Engineering, University of Florida, Gainesville 32611 8300, USA
    J Nucl Med 44:774-83. 2003
    ....
  58. ncbi request reprint Site-specific OH attack to the sugar moiety of DNA: a comparison of experimental data and computational simulation
    Bulent Aydogan
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611, USA
    Radiat Res 157:38-44. 2002
    ..in which OH radicals exhibit preferential initial attack at sugar hydrogen atoms in the order 1H(5')+2H(5') > H(4') > H(3') > 1H(2')+2H(2') > H(1')...
  59. ncbi request reprint Kilovoltage stereotactic radiosurgery for age-related macular degeneration: assessment of optic nerve dose and patient effective dose
    Justin Hanlon
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611, USA
    Med Phys 36:3671-81. 2009
    ..The estimated effective dose was 0.28 mSv which is comparable to diagnostic procedures such as a head radiograph and a factor of 10 lower than a head CT scan...
  60. doi request reprint The influence of patient size on dose conversion coefficients: a hybrid phantom study for adult cardiac catheterization
    Perry Johnson
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611, USA
    Phys Med Biol 54:3613-29. 2009
    ....
  61. ncbi request reprint Uncertainties in electron-absorbed fractions and lung doses from inhaled beta-emitters
    Eduardo B Farfan
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611, USA
    Health Phys 88:37-47. 2005
    ..0 code, Reference Man doses for inhaled beta-emitters were shown to provide slightly conservative estimates of lung dose compared to those in this study where uncertainties in lung airway histology are considered...
  62. doi request reprint Canine anatomic phantom for preclinical dosimetry in internal emitter therapy
    LAURA PADILLA
    Department of Nuclear and Radiological Engineering, College of Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    J Nucl Med 49:446-52. 2008
    ..The main objective of this study was to construct a 3-dimensional computational phantom of a large dog on the basis of whole-body multislice CT data...
  63. ncbi request reprint Organ and effective doses in newborn patients during helical multislice computed tomography examination
    Robert J Staton
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611, USA
    Phys Med Biol 51:5151-66. 2006
    ..For all scans, the effective dose was found to range approximately 1-13 mSv across the scan parameters and scan regions. The largest effective dose occurred for CAP scans at 120 kVp...
  64. ncbi request reprint Individual variations in mucosa and total wall thickness in the stomach and rectum assessed via endoscopic ultrasound
    C H Huh
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611, USA
    Physiol Meas 24:N15-22. 2003
    ..These values can thus be utilized to investigate uncertainties in alimentary tract dosimetry that are based upon fixed reference individual definitions of organ wall structure...
  65. doi request reprint Anthropometric approaches and their uncertainties to assigning computational phantoms to individual patients in pediatric dosimetry studies
    Scott Whalen
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611, USA
    Phys Med Biol 53:453-71. 2008
    ..An expanded series of non-uniform rational B-spine (NURBS) pediatric phantoms are being created at the University of Florida to allow the full application of this new approach in pediatric medical imaging studies...
  66. ncbi request reprint Hybrid computational phantoms of the male and female newborn patient: NURBS-based whole-body models
    Choonsik Lee
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611, USA
    Phys Med Biol 52:3309-33. 2007
    ....
  67. ncbi request reprint Organ and effective doses in pediatric patients undergoing helical multislice computed tomography examination
    Choonik Lee
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    Med Phys 34:1858-73. 2007
    ....
  68. ncbi request reprint Dosimetry characterization of a multibeam radiotherapy treatment for age-related macular degeneration
    Choonsik Lee
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611, USA
    Med Phys 35:5151-60. 2008
    ..The results of this study dem onstrate the therapeutic promise of this device and provide important information for further design and clinical implementation for radiotherapy treatments for ARMD...
  69. ncbi request reprint The UF series of tomographic computational phantoms of pediatric patients
    Choonik Lee
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611, USA
    Med Phys 32:3537-48. 2005
    ....
  70. ncbi request reprint Revisions to the ORNL series of adult and pediatric computational phantoms for use with the MIRD schema
    Eun Young Han
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Health Phys 90:337-56. 2006
    ..Consequently, stylized pediatric phantoms will continue to fill this data need in medical dosimetry...
  71. ncbi request reprint Consideration of the ICRP 2006 revised tissue weighting factors on age-dependent values of the effective dose for external photons
    Choonsik Lee
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611, USA
    Phys Med Biol 52:41-58. 2007
    ....
  72. ncbi request reprint Correlations of total pelvic spongiosa volume with both anthropometric parameters and computed tomography-based skeletal size measurements
    James M Brindle
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL 32611 8300, USA
    Cancer Biother Radiopharm 21:352-63. 2006
    ..Skeletal height measurements appear to have a much higher correlation with TPSV than either their corresponding skeletal width measurements or parameters that are a function of an individual's TBM...
  73. ncbi request reprint Blood-based red marrow dosimetry: where's the beef?
    Jeffry A Siegel
    J Nucl Med 46:1404-6; author reply 1405-6. 2005
  74. ncbi request reprint Derivation of site-specific skeletal masses within the current ICRP age series
    Christopher J Watchman
    Department of Radiation Oncology, University of Arizona, Tucson, AZ 85724, USA
    Phys Med Biol 52:3133-50. 2007
    ..New data for a revised surrogate tissue region for the osteoprogenitor cells within bone marrow is presented with estimates of its total mass throughout the skeleton and for different subject ages...
  75. ncbi request reprint Bone marrow dosimetry using blood-based models for radiolabeled antibody therapy: a multiinstitutional comparison
    Barry W Wessels
    Department of Radiation Oncology, Case Western Reserve University, Cleveland, Ohio
    J Nucl Med 45:1725-33. 2004
    ..Differences in dose estimates associated with starting assumptions and the exact implementation of the AAPM/Sgouros calculation methodology used by the source institutions and the central facility were quantified and compared...
  76. pmc Assessment of organ-specific neutron equivalent doses in proton therapy using computational whole-body age-dependent voxel phantoms
    Christina Zacharatou Jarlskog
    Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Phys Med Biol 53:693-717. 2008
    ..The neutron dose from a course of proton therapy treatment (assuming 70 Gy in 30 fractions) could potentially (depending on patient's age, organ, treatment site and area of CT scan) be equivalent to up to approximately 30 CT scans...
  77. doi request reprint Monte carlo simulations of site-specific radical attack to DNA bases
    Bulent Aydogan
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois 60637, USA
    Radiat Res 169:223-31. 2008
    ....
  78. ncbi request reprint Spatial distribution of blood vessels and CD34+ hematopoietic stem and progenitor cells within the marrow cavities of human cancellous bone
    Christopher J Watchman
    Department of Radiation Oncology, University of Arizona, Tucson, Arizona, USA
    J Nucl Med 48:645-54. 2007
    ..The objective of the present study was to directly measure the spatial concentration of these cells, as well as marrow vasculature structures, within images of human disease-free bone marrow...

Research Grants3

  1. TOMOGRAPHIC DOSIMETRY PHANTOMS FOR PEDIATRIC RADIOLOGY
    Wesley Bolch; Fiscal Year: 2002
    ....
  2. Advances in Skeletal Dosimetry Through Microimaging
    Wesley Bolch; Fiscal Year: 2006
    ..abstract_text> ..
  3. TOMOGRAPHIC DOSIMETRY PHANTOMS FOR PEDIATRIC RADIOLOGY
    Wesley Bolch; Fiscal Year: 2001
    ....