William A Blattner
Affiliation: University of Maryland
- Rapid clearance of virus after acute HIV-1 infection: correlates of risk of AIDSWilliam A Blattner
Institute of Human Virology, University of Maryland, Baltimore, Maryland, USA
J Infect Dis 189:1793-801. 2004..Our objective was to define early virologic and immunologic determinants of human immunodeficiency virus (HIV) type 1 disease progression among 22 case subjects with acute infection from the Trinidad Seroconvertor Cohort...
- HIV-1 epidemic in the Caribbean is dominated by subtype BYuka Nadai
Institute of Human Virology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America
PLoS ONE 4:e4814. 2009..To expand our knowledge of this, nearly full genome amplification, sequencing and analysis was conducted...
- Elevated hypermutation levels in HIV-1 natural viral suppressorsLindsay M Eyzaguirre
Institute of Human Virology, University of Maryland School of Medicine, Baltimore, United States 725 West Lombard Street Baltimore, MD 21201, USA
Virology 443:306-12. 2013..043). Our data suggests that inactivation of the virus through the APOBEC3G system may contribute to the NVS phenotype...
- Protocol for nearly full-length sequencing of HIV-1 RNA from plasmaYuka Nadai
Department of Epidemiology, Institute of Human Virology, University of Maryland, Baltimore, Maryland, USA
PLoS ONE 3:e1420. 2008..This protocol provides a useful tool for molecular analysis to understand the HIV epidemic and pathogenesis, as well as diagnosis, therapy and future vaccine strategies...
- Improved classification of recent HIV-1 infection by employing a two-stage sensitive/less-sensitive test strategyNiel T Constantine
Department of Pathology, University of Maryland, School of Medicine, Baltimore, Maryland 21201, USA
J Acquir Immune Defic Syndr 32:94-103. 2003....
- Clinical features and preliminary studies of virological correlates of neurocognitive impairment among HIV-infected individuals in NigeriaWalter Royal
Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA
J Neurovirol 18:191-9. 2012....
- Risk factors for in utero and intrapartum transmission of HIVLaurence S Magder
Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, MD, USA
J Acquir Immune Defic Syndr 38:87-95. 2005..To identify predictors of in utero and intrapartum HIV-1 transmission in infants born in the Women and Infants Transmission Study between 1990 and 2000...
- Associations between Cognition, Gender and Monocyte Activation among HIV Infected Individuals in NigeriaWalter Royal
Department of Neurology, University of Maryland, School of Medicine, Baltimore, Maryland, United States of America
PLoS ONE 11:e0147182. 2016..These studies suggest that the risk of developing NCI differ for HIV infected women and men in Nigeria and, for women, may be linked to effects from higher plasma levels of HIV driving activation of circulating monocytes. ..
- Correlates of Patient Retention in HIV Care and Treatment Programs in NigeriaChinenye Ugoji
Institute of Human Virology, University of Maryland School of Medicine, Baltimore, USA
Curr HIV Res 13:300-7. 2015..Understanding determinants of retention will inform retention strategies. We evaluated the correlates of retention in a large HIV program in Nigeria...
- Neurocognitive impairment associated with predominantly early stage HIV infection in Abuja, NigeriaChristopher Akolo
The Institute of Human Virology at the University of Maryland School of Medicine, Baltimore, MD, USA
J Neurovirol 20:380-7. 2014..Confirmation of these findings awaits analyses using data from a larger number of control subjects...
- A cohort study of health effects of human T-cell lymphotropic virus type I infection in Jamaican childrenElizabeth M Maloney
Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, Bethesda, Maryland, USA
Pediatrics 112:e136-42. 2003..Although HTLV-I is known to be associated with infective dermatitis in childhood, other HTLV-I-associated morbidity in children has not been well studied. We sought to determine the HTLV-I-associated health effects in Jamaican children...
- Prevalence of Anal High-Risk Human Papillomavirus Infections Among HIV-Positive and HIV-Negative Men Who Have Sex With Men in NigeriaRebecca G Nowak
From the Institute of Human Virology and Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD University of New Mexico Health Sciences Center, Albuquerque, NM University of Maryland School of Public Health, College Park, Md Johns Hopkins Bloomberg School of Public Health, Baltimore, MD and Institute of Human Virology Nigeria, Federal Capital Territory, Nigeria
Sex Transm Dis 43:243-8. 2016..This study evaluated anal HR-HPV in Nigeria among HIV-positive and HIV-negative men who have sex with men (MSM) for future immunization recommendations...
- Tenofovir-based regimens associated with less drug resistance in HIV-1-infected Nigerians failing first-line antiretroviral therapyMary Ann A Etiebet
Institute of Human Virology, University of Maryland School of Medicine, MD, USA
AIDS 27:553-61. 2013..We retrospectively conducted genotypic analysis on archived samples from Nigerian patients who received targeted viral load testing to confirm treatment failure and report their drug resistance mutation patterns...
- Development of vaccination strategies that elicit broadly neutralizing antibodies against human immunodeficiency virus type 1 in both the mucosal and systemic immune compartmentsDavid M Hone
Divisions of Basic Science and Vaccine Research, Institute of Human Virology, University of Maryland Biotechnology Institute, Baltimore, Maryland 21201, USA
J Hum Virol 5:17-23. 2002..This paper reviews recent advances made by the authors toward the development of an HIV-1 vaccine that elicits such antibodies in both the mucosal and systemic immune compartments...
- Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infectionBrandon F Keele
Departments of Medicine and Microbiology, University of Alabama at Birmingham, Birmingham, AL 35223, USA
Proc Natl Acad Sci U S A 105:7552-7. 2008....
- Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trialNina D Russell
Program in Infectious Diseases, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
J Acquir Immune Defic Syndr 44:203-12. 2007..We conducted a phase 2 trial to determine if a canarypox vaccine candidate (vCP1452) administered with rgp120 subunit protein would "qualify" for a trial to define a correlate of efficacy...
- Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteersPaul A Goepfert
University of Alabama at Birmingham, 908 20th Street South, CCB 328, Birmingham, AL 35294, USA
Vaccine 25:510-8. 2007..Use of the recombinant proteins NefTat and gp120(W61D) formulated with the AS02A adjuvant system was previously shown to protect against AIDS in a rhesus macaque SHIV animal model system...
- High-dose recombinant Canarypox vaccine expressing HIV-1 protein, in seronegative human subjectsPaul A Goepfert
Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 2050, USA
J Infect Dis 192:1249-59. 2005..0) TCID50 (60 participants) than when given at the regular dose, 10(7.26) TCID50 (40 participants); as a control, a placebo vaccine preparation also was administered (10 participants)...
- Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothersMiriam C Poirier
Carcinogen DNA Interactions Section, National Cancer Institute, National Institutes of Health, Building 37, Room 4032, 37 Convent Drive, Bethesda, MD 20892 4255, USA
J Acquir Immune Defic Syndr 33:175-83. 2003..The study shows that children of HIV+ mothers are at risk for mitochondrial damage that is further increased in infants of mothers receiving AZT during pregnancy...
- HIV-1 Incidence and Genetic Diversity in the CaribbeanWilliam Blattner; Fiscal Year: 2004....
- Impact of Alcohol Consumption on HIV/AIDS in WomenWilliam Blattner; Fiscal Year: 2005..to-child transmission of HIV. ..
- COALITION FOR HIV VACCINE DEVELOPMENTWilliam Blattner; Fiscal Year: 2006..abstract_text> ..