Jason H Barker
Affiliation: University of Iowa
- Fatal type 3 adenoviral pneumonia in immunocompetent adult identical twinsJason H Barker
Department of Internal Medicine, University of Iowa, Iowa City, IA, USA
Clin Infect Dis 37:e142-6. 2003..We describe adult twin sisters who developed severe adenoviral pneumonia with relative leukopenia, progressive focal infiltrates, shock, and hypoxia. Potential determinants of severe adenoviral disease are discussed...
- The role of complement opsonization in interactions between F. tularensis subsp. novicida and human neutrophilsJason H Barker
Inflammation Program and Department of Medicine, Veterans Affairs Medical Center and The University of Iowa, Coralville, IA 52241, USA
Microbes Infect 11:762-9. 2009..tularensis subsp. novicida. Taken together, our results reveal important differences between these two strains of F. tularensis and may, in part, explain the low virulence of F. tularensis subsp. novicida for humans...
- Natural IgM mediates complement-dependent uptake of Francisella tularensis by human neutrophils via complement receptors 1 and 3 in nonimmune serumJustin T Schwartz
Inflammation Program, University of Iowa and Veterans Administration Medical Center, Iowa City, IA 52242, USA
J Immunol 189:3064-77. 2012..tularensis and initiates the classical complement cascade via C1q to promote C3 opsonization of the bacterium and phagocytosis via CR3 and either CR1 or CR4 in a phagocyte-specific manner...
- Francisella tularensis inhibits the intrinsic and extrinsic pathways to delay constitutive apoptosis and prolong human neutrophil lifespanJustin T Schwartz
Inflammation Program, University of Iowa and the Veterans Administration Medical Center, Iowa City, IA 52242, USA
J Immunol 188:3351-63. 2012....
- Evidence Suggesting That Francisella tularensis O-Antigen Capsule Contains a Lipid A-Like Molecule That Is Structurally Distinct from the More Abundant Free Lipid AJason H Barker
Inflammation Program and Department of Internal Medicine, University of Iowa, Iowa City, IA, United States of America, and Veterans Affairs Medical Center, Iowa City, IA, United States of America
PLoS ONE 11:e0157842. 2016....
- Basis for the failure of Francisella tularensis lipopolysaccharide to prime human polymorphonuclear leukocytesJason H Barker
Inflammation Program and Department of Medicine, University of Iowa, D160 MTF, 2501 Crosspark Road, Coralville, IA, 52241, USA
Infect Immun 74:3277-84. 2006..tularensis LPS and the resistance of F. tularensis to oxygen-independent PMN killing may result from the inability of F. tularensis LPS to be recognized by these important LPS-sensing molecules of the innate immune system...
- Metabolic labeling to characterize the overall composition of Francisella lipid A and LPS grown in broth and in human phagocytesJason H Barker
1Inflammation Program and Department of Medicine, University of Iowa and Veterans Affairs Medical Center, IA, USA
Innate Immun 20:88-103. 2014....