Brian A Baldo

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. doi request reprint Prefrontal Cortical Opioids and Dysregulated Motivation: A Network Hypothesis
    Brian A Baldo
    Department of Psychiatry, University of Wisconsin Madison School of Medicine and Public Health, 6001 Research Park Blvd, Madison, WI 53719, USA Electronic address
    Trends Neurosci 39:366-77. 2016
  2. pmc Principles of motivation revealed by the diverse functions of neuropharmacological and neuroanatomical substrates underlying feeding behavior
    Brian A Baldo
    Department of Psychiatry, University of Wisconsin Madison School of Medicine and Public Health, 6001 Research Park Blvd, Madison, WI 53719, USA Neuroscience Training Program, University of Wisconsin Madison School of Medicine and Public Health, 6001 Research Park Blvd, Madison, WI 53719, USA Electronic address
    Neurosci Biobehav Rev 37:1985-98. 2013
  3. ncbi request reprint Discrete neurochemical coding of distinguishable motivational processes: insights from nucleus accumbens control of feeding
    Brian A Baldo
    Department of Psychiatry, University of Wisconsin Madison School of Medicine and Public Health, 6001 Research Park Blvd, Madison, WI, 53719, USA
    Psychopharmacology (Berl) 191:439-59. 2007
  4. ncbi request reprint Hyperphagia induced by GABAA receptor-mediated inhibition of the nucleus accumbens shell: dependence on intact neural output from the central amygdaloid region
    Brian A Baldo
    Department of Psychiatry, School of Medicine, University of Wisconsin Madison, 6001 Research Park Boulevard, WI 53719, USA
    Behav Neurosci 119:1195-206. 2005
  5. ncbi request reprint Activation of a subpopulation of orexin/hypocretin-containing hypothalamic neurons by GABAA receptor-mediated inhibition of the nucleus accumbens shell, but not by exposure to a novel environment
    Brian A Baldo
    Department of Psychiatry, University of Madison Wisconsin, School of Medicine, 6001 Research Park Blvd, Madison, Wisconsin 53719, USA
    Eur J Neurosci 19:376-86. 2004
  6. ncbi request reprint Corticostriatal-hypothalamic circuitry and food motivation: integration of energy, action and reward
    Ann E Kelley
    Department of Psychiatry, University of Wisconsin Madison Medical School, 6001 Research Park Blvd, Madison, WI 53719, USA
    Physiol Behav 86:773-95. 2005
  7. pmc Mu-opioid stimulation in rat prefrontal cortex engages hypothalamic orexin/hypocretin-containing neurons, and reveals dissociable roles of nucleus accumbens and hypothalamus in cortically driven feeding
    Jesus D Mena
    Neuroscience Training Program and Department of Psychiatry, University of Wisconsin Madison, Madison, Wisconsin 53719
    J Neurosci 33:18540-52. 2013
  8. pmc Upregulation of gene expression in reward-modulatory striatal opioid systems by sleep loss
    Brian A Baldo
    1 Department of Psychiatry, University of Wisconsin Madison, School of Medicine and Public Health, Madison, WI, USA 2 Neuroscience Training Program, University of Wisconsin Madison, School of Medicine and Public Health, Madison, WI, USA
    Neuropsychopharmacology 38:2578-87. 2013
  9. ncbi request reprint Increases in food intake or food-seeking behavior induced by GABAergic, opioid, or dopaminergic stimulation of the nucleus accumbens: is it hunger?
    Erin C Hanlon
    Neuroscience Training Program, University of Wisconsin Madison, 6001 Research Park Boulevard, Madison, WI 53719, USA
    Psychopharmacology (Berl) 172:241-7. 2004
  10. pmc REM sleep deprivation produces a motivational deficit for food reward that is reversed by intra-accumbens amphetamine in rats
    Erin C Hanlon
    University of Wisconsin Madison, 53719, USA
    Brain Res Bull 83:245-54. 2010

Collaborators

Detail Information

Publications24

  1. doi request reprint Prefrontal Cortical Opioids and Dysregulated Motivation: A Network Hypothesis
    Brian A Baldo
    Department of Psychiatry, University of Wisconsin Madison School of Medicine and Public Health, 6001 Research Park Blvd, Madison, WI 53719, USA Electronic address
    Trends Neurosci 39:366-77. 2016
    ..Evidence supporting this hypothesis from human imaging and animal studies will be discussed, and combinatorial drug treatments targeting μ-ORs and specific PFC subcortical targets will be explored. ..
  2. pmc Principles of motivation revealed by the diverse functions of neuropharmacological and neuroanatomical substrates underlying feeding behavior
    Brian A Baldo
    Department of Psychiatry, University of Wisconsin Madison School of Medicine and Public Health, 6001 Research Park Blvd, Madison, WI 53719, USA Neuroscience Training Program, University of Wisconsin Madison School of Medicine and Public Health, 6001 Research Park Blvd, Madison, WI 53719, USA Electronic address
    Neurosci Biobehav Rev 37:1985-98. 2013
    ..We will conclude by discussing implications for understanding disorders of "non-homeostatic" feeding. ..
  3. ncbi request reprint Discrete neurochemical coding of distinguishable motivational processes: insights from nucleus accumbens control of feeding
    Brian A Baldo
    Department of Psychiatry, University of Wisconsin Madison School of Medicine and Public Health, 6001 Research Park Blvd, Madison, WI, 53719, USA
    Psychopharmacology (Berl) 191:439-59. 2007
    ....
  4. ncbi request reprint Hyperphagia induced by GABAA receptor-mediated inhibition of the nucleus accumbens shell: dependence on intact neural output from the central amygdaloid region
    Brian A Baldo
    Department of Psychiatry, School of Medicine, University of Wisconsin Madison, 6001 Research Park Boulevard, WI 53719, USA
    Behav Neurosci 119:1195-206. 2005
    ..Intra-CeA tetrodotoxin infusions also blocked intra-Acb shell muscimol-induced hyperphagia. Hence, feeding elicited by intra-Acb shell GABA(A) receptor stimulation requires intact neural output from the CeA but not the BLA...
  5. ncbi request reprint Activation of a subpopulation of orexin/hypocretin-containing hypothalamic neurons by GABAA receptor-mediated inhibition of the nucleus accumbens shell, but not by exposure to a novel environment
    Brian A Baldo
    Department of Psychiatry, University of Madison Wisconsin, School of Medicine, 6001 Research Park Blvd, Madison, Wisconsin 53719, USA
    Eur J Neurosci 19:376-86. 2004
    ....
  6. ncbi request reprint Corticostriatal-hypothalamic circuitry and food motivation: integration of energy, action and reward
    Ann E Kelley
    Department of Psychiatry, University of Wisconsin Madison Medical School, 6001 Research Park Blvd, Madison, WI 53719, USA
    Physiol Behav 86:773-95. 2005
    ....
  7. pmc Mu-opioid stimulation in rat prefrontal cortex engages hypothalamic orexin/hypocretin-containing neurons, and reveals dissociable roles of nucleus accumbens and hypothalamus in cortically driven feeding
    Jesus D Mena
    Neuroscience Training Program and Department of Psychiatry, University of Wisconsin Madison, Madison, Wisconsin 53719
    J Neurosci 33:18540-52. 2013
    ..g., binge eating and opiate or alcohol abuse, disorders in which μORs and aberrant cortical activation have been implicated. ..
  8. pmc Upregulation of gene expression in reward-modulatory striatal opioid systems by sleep loss
    Brian A Baldo
    1 Department of Psychiatry, University of Wisconsin Madison, School of Medicine and Public Health, Madison, WI, USA 2 Neuroscience Training Program, University of Wisconsin Madison, School of Medicine and Public Health, Madison, WI, USA
    Neuropsychopharmacology 38:2578-87. 2013
    ..The recruitment of telencephalic food-reward systems may provide a feeding drive highly resistant to feedback control, which could engender obesity through the enhancement of palatable feeding. ..
  9. ncbi request reprint Increases in food intake or food-seeking behavior induced by GABAergic, opioid, or dopaminergic stimulation of the nucleus accumbens: is it hunger?
    Erin C Hanlon
    Neuroscience Training Program, University of Wisconsin Madison, 6001 Research Park Boulevard, Madison, WI 53719, USA
    Psychopharmacology (Berl) 172:241-7. 2004
    ..However, it is not known whether such stimulation mimics a motivational state of food deprivation that commonly enables animals to learn a new operant response to obtain food...
  10. pmc REM sleep deprivation produces a motivational deficit for food reward that is reversed by intra-accumbens amphetamine in rats
    Erin C Hanlon
    University of Wisconsin Madison, 53719, USA
    Brain Res Bull 83:245-54. 2010
    ..These data suggest that decreased motivation for food reward caused by REMSD may result from a suppression of dopamine function in the Acb...
  11. pmc Intra-accumbens infusion of a muscarinic antagonist reduces food intake without altering the incentive properties of food-associated cues
    Michelle L Perry
    Molecular and Cellular Pharmacology and Department of Psychiatry, University of Wisconsin, Madison, WI, USA
    Behav Neurosci 124:44-54. 2010
    ..This study contributes to the growing evidence that goal-seeking behaviors are mediated by a set of neural processes distinct from those governing food reward...
  12. ncbi request reprint Overlapping distributions of orexin/hypocretin- and dopamine-beta-hydroxylase immunoreactive fibers in rat brain regions mediating arousal, motivation, and stress
    Brian A Baldo
    Department of Psychiatry, University of Wisconsin Madison Medical School, 6001 Research Park Blvd, Madison, Wisconsin 53719, USA
    J Comp Neurol 464:220-37. 2003
    ....
  13. ncbi request reprint A proposed hypothalamic-thalamic-striatal axis for the integration of energy balance, arousal, and food reward
    Ann E Kelley
    Department of Psychiatry, University of Wisconsin Madison Medical School, Madison, Wisconsin 53719, USA
    J Comp Neurol 493:72-85. 2005
    ....
  14. pmc Sweetened-fat intake sensitizes gamma-aminobutyric acid-mediated feeding responses elicited from the nucleus accumbens shell
    Sarah Newman
    Department of Psychiatry, University of Wisconsin Madison School of Medicine and Public Health, Madison, Wisconsin, USA
    Biol Psychiatry 73:843-50. 2013
    ..Nevertheless, it is unknown whether feeding-induced neuroadaptations occur in this system...
  15. pmc Muscarinic receptor antagonism causes a functional alteration in nucleus accumbens mu-opiate-mediated feeding behavior
    Michelle L Perry
    Molecular and Cellular Pharmacology, University of Wisconsin Madison, 6001 Research Park Boulevard, Madison, WI 53719, USA
    Behav Brain Res 197:225-9. 2009
    ..Hence, Acb muscarinic manipulations exhibit some specificity for feeding, perhaps via interactions with the striatal opioid system...
  16. pmc Antipsychotic-like actions of the satiety peptide, amylin, in ventral striatal regions marked by overlapping calcitonin receptor and RAMP-1 gene expression
    Sarah K Baisley
    Neuroscience Training Program, University of Wisconsin Madison, Medical Sciences Center, Madison, Wisconsin 53706, and Department of Psychiatry, University of Wisconsin Madison, Wisconsin 53719
    J Neurosci 34:4318-25. 2014
    ..Moreover, AMY1-Rs may represent a novel way to modulate activity preferentially in ventral versus dorsal striatum. ..
  17. pmc Induction of hyperphagia and carbohydrate intake by μ-opioid receptor stimulation in circumscribed regions of frontal cortex
    Jesus D Mena
    Neuroscience Training Program, University of Wisconsin Madison, Madison, Wisconsin 53719, USA
    J Neurosci 31:3249-60. 2011
    ..These findings may have implications for understanding affect-driven feeding and loss of restraint in eating disorders...
  18. ncbi request reprint Effects of selective dopamine D1 or D2 receptor blockade within nucleus accumbens subregions on ingestive behavior and associated motor activity
    Brian A Baldo
    Department of Psychiatry, University of Wisconsin Madison Medical School, 6001 Research Park Blvd, Madison, WI 53719, USA
    Behav Brain Res 137:165-77. 2002
    ..These results are discussed with regard to current theories of dopaminergic control of feeding behavior, and with reference to the functional heterogeneity of Acb subregions...
  19. pmc Endogenous Opioid Signaling in the Medial Prefrontal Cortex is Required for the Expression of Hunger-Induced Impulsive Action
    Ryan A Selleck
    Neuroscience Training Program, University of Wisconsin Madison, School of Medicine and Public Health, Madison, WI, USA
    Neuropsychopharmacology 40:2464-74. 2015
    ..Opioid antagonists may represent effective treatments for a range of psychiatric disorders with impulsivity features...
  20. pmc GABA-Mediated Inactivation of Medial Prefrontal and Agranular Insular Cortex in the Rat: Contrasting Effects on Hunger- and Palatability-Driven Feeding
    Brian A Baldo
    Department of Psychiatry, School of Medicine and Public Health, University of Wisconsin Madison, Madison, WI, USA
    Neuropsychopharmacology 41:960-70. 2016
    ....
  21. pmc Overlapping striatal sites mediate scopolamine-induced feeding suppression and mu-opioid-mediated hyperphagia in the rat
    Michelle L Perry
    Molecular and Cellular Pharmacology, University of Wisconsin Madison, 6001 Research Park Blvd, Madison, WI, 53719, USA
    Psychopharmacology (Berl) 231:919-28. 2014
    ..One might therefore expect the effects of scopolamine to conform to similar boundaries, but a systematic mapping of scopolamine-induced feeding suppression has not yet been undertaken...
  22. pmc Predator Stress-Induced CRF Release Causes Enduring Sensitization of Basolateral Amygdala Norepinephrine Systems that Promote PTSD-Like Startle Abnormalities
    Abha K Rajbhandari
    Neuroscience Training Program, University of Wisconsin Madison, Madison, Wisconsin 53719
    J Neurosci 35:14270-85. 2015
    ..Hence, we reveal a discrete neural pathway mediating the enhancement of NE system function seen in PTSD, and we offer a model for characterizing potential new treatments that may work by modulating this BLA circuitry...
  23. pmc Amylin receptor signaling in the nucleus accumbens negatively modulates μ-opioid-driven feeding
    Sarah K Baisley
    Neuroscience Training Program, University of Wisconsin Madison, Medical Sciences Center, University Ave Madison, WI, USA
    Neuropsychopharmacology 39:3009-17. 2014
    ....
  24. ncbi request reprint Immunoglobulin E binding determinants on beta-lactam drugs
    Brian A Baldo
    Research Laboratory, NSL Health Limited, Melbourne, Victoria, Australia
    Curr Opin Allergy Clin Immunol 2:297-300. 2002
    ..The present review summarizes the most recent advances in studies of structural aspects of beta-lactams as allergens...