Affiliation: University of Mississippi
- A survey of synthetic and natural phytotoxic compounds and phytoalexins as potential antimalarial compoundsJoanna Bajsa
National Center for Natural Products Research, School of Pharmacy, University of Mississippi, MS 38677, U S A
Biol Pharm Bull 30:1740-4. 2007....
- Plasmodium falciparum serine/threonine phoshoprotein phosphatases (PPP): from housekeeper to the 'holy grail'Joanna Bajsa
United States Department of Agriculture Natural Products Utilization Research Unit, National Center for Natural Products Research, University, MS 38677, USA
Curr Drug Targets 9:997-1012. 2008..Identification of distinct molecular and functional characteristics of these enzymes shall be useful in designing selective inhibitors of plasmodial PPPs as potential new antimalarials...
- The antiplasmodial activity of norcantharidin analogsJoanna Bajsa
USDA, ARS, Natural Products Utilization Research Unit, University, MS 38677, USA
Bioorg Med Chem Lett 20:6688-95. 2010..Surprisingly, seven norcantharimides also displayed good antiplasmodial activity with the most potent, 5 returning D6=8.9±0.9 and W2 IC(50)=12.5±2.2 μM, representing a fivefold enhancement over norcantharidin...
- Serine/threonine protein phosphatases: multi-purpose enzymes in control of defense mechanismsJoanna Bajsa
Natural Products Utilization Research Unit, Agricultural Research Service, United States Department of Agriculture, Oxford, MS, USA
Plant Signal Behav 6:1921-5. 2011....
- Omics methods for probing the mode of action of natural and synthetic phytotoxinsStephen O Duke
NPURU, USDA, ARS, P O Box 8048, University, MS 38677, USA
J Chem Ecol 39:333-47. 2013..Such information can be useful in understanding the full impact of natural phytotoxins in both agricultural and natural ecosystems...
- Is (-)-catechin a novel weapon of spotted knapweed (Centaurea stoebe)?Stephen O Duke
NPURU, USDA, ARS, University, Oxford, MS 38677, USA
J Chem Ecol 35:141-53. 2009..Our findings suggest that catechin is not a novel weapon of spotted knapweed and that other allelochemical(s) or alternative mechanisms must be found to explain the success of this species as an invader in North America...
- Transcriptional responses to cantharidin, a protein phosphatase inhibitor, in Arabidopsis thaliana reveal the involvement of multiple signal transduction pathwaysJoanna Bajsa
Natural Products Utilization Research Unit, USDA, ARS, University of Mississippi, University, MS 38677, USA
Physiol Plant 143:188-205. 2011..They function as negative regulators modifying receptor functions, thus altering signaling that influences transcriptional responses...
- Cantharidin, a protein phosphatase inhibitor, strongly upregulates detoxification enzymes in the Arabidopsis proteomeJoanna Bajsa
USDA, ARS, Natural Products Utilization Research Unit, Cochran Research Center, University, MS 38677, USA
J Plant Physiol 173:33-40. 2015....
- The case against (-)-catechin involvement in allelopathy of Centaurea stoebe (spotted knapweed)Stephen O Duke
Natural Products Utilization Research Unit, Agricultural Research Service, United States Department of Agriculture, Oxford, MI, USA
Plant Signal Behav 4:422-4. 2009..Furthermore, the claim that (-)-catechin acts as a phytotoxin through causing oxidative damage is refuted by the fact that the molecule is a strong antioxidant and is quickly degraded by extracellular root enzymes...