Ofelia Alvarez

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. pmc Effect of hydroxyurea treatment on renal function parameters: results from the multi-center placebo-controlled BABY HUG clinical trial for infants with sickle cell anemia
    Ofelia Alvarez
    Division of Pediatric Hematology, University of Miami, Miami, Florida 33136, USA
    Pediatr Blood Cancer 59:668-74. 2012
  2. ncbi request reprint Thoracic lymphangiomatosis in a child
    Ofelia A Alvarez
    Department of Pediatrics, University of Miami, Miami, Florida 33101, USA
    J Pediatr Hematol Oncol 26:136-41. 2004
  3. ncbi request reprint Serum cystatin C levels in children with sickle cell disease
    Ofelia Alvarez
    Division of Pediatric Hematology, University of Miami, 1611 NW 12th Avenue, ACC West, Rm 514, Miami, FL 33136, USA
    Pediatr Nephrol 21:533-7. 2006
  4. doi request reprint Short-term follow-up of patients with sickle cell disease and albuminuria
    Ofelia Alvarez
    Division of Pediatric Hematology, University of Miami Miller School of Medicine, Miami, Florida, USA
    Pediatr Blood Cancer 50:1236-9. 2008
  5. pmc Pain and other non-neurological adverse events in children with sickle cell anemia and previous stroke who received hydroxyurea and phlebotomy or chronic transfusions and chelation: results from the SWiTCH clinical trial
    Ofelia Alvarez
    Department of Pediatrics, Division of Pediatric Hematology, University of Miami, Miami, Florida
    Am J Hematol 88:932-8. 2013
  6. pmc Impact of hydroxyurea on clinical events in the BABY HUG trial
    Courtney D Thornburg
    Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    Blood 120:4304-10; quiz 4448. 2012
  7. ncbi request reprint Primary renal botryoid rhabdomyosarcoma: diagnosis and outcome
    Juan E Sola
    Pediatric Surgery, University of Miami, Jackson Memorial Medical Center, Miami, FL 33136, USA
    J Pediatr Surg 42:e17-20. 2007
  8. doi request reprint Wilms' tumor, pancreatic islet cell carcinoma, and pheochromocytoma in a child
    Juan E Sola
    Pediatric Surgery, University of Miami, Jackson Memorial Medical Center, Miami, FL 33136, USA
    J Pediatr Surg 43:E25-9. 2008
  9. doi request reprint Abnormalities in renal tubular phosphate handling in children with sickle cell disease
    Vimal Master Sankar Raj
    Division of Pediatric Nephrology, University of Miami, Miami, Florida
    Pediatr Blood Cancer 61:2267-70. 2014
  10. pmc Biomarkers of splenic function in infants with sickle cell anemia: baseline data from the BABY HUG Trial
    Zora R Rogers
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390 9063, USA
    Blood 117:2614-7. 2011

Detail Information

Publications17

  1. pmc Effect of hydroxyurea treatment on renal function parameters: results from the multi-center placebo-controlled BABY HUG clinical trial for infants with sickle cell anemia
    Ofelia Alvarez
    Division of Pediatric Hematology, University of Miami, Miami, Florida 33136, USA
    Pediatr Blood Cancer 59:668-74. 2012
    ..The Phase III randomized double-blinded Clinical Trial of Hydroxyurea in Infants with SCA (BABY HUG) tested the hypothesis that hydroxyurea can prevent kidney dysfunction by reducing hyperfiltration...
  2. ncbi request reprint Thoracic lymphangiomatosis in a child
    Ofelia A Alvarez
    Department of Pediatrics, University of Miami, Miami, Florida 33101, USA
    J Pediatr Hematol Oncol 26:136-41. 2004
    ..0% mortality). All patients who died had either parenchymal lung involvement or pleural effusion. Thoracic lymphangiomatosis should be included in the differential diagnosis of a mediastinal mass with pulmonary findings...
  3. ncbi request reprint Serum cystatin C levels in children with sickle cell disease
    Ofelia Alvarez
    Division of Pediatric Hematology, University of Miami, 1611 NW 12th Avenue, ACC West, Rm 514, Miami, FL 33136, USA
    Pediatr Nephrol 21:533-7. 2006
    ..We conclude that serum cystatin C correlates with the level of albuminuria and may be a reliable method to measure renal function in SCD...
  4. doi request reprint Short-term follow-up of patients with sickle cell disease and albuminuria
    Ofelia Alvarez
    Division of Pediatric Hematology, University of Miami Miller School of Medicine, Miami, Florida, USA
    Pediatr Blood Cancer 50:1236-9. 2008
    ..The purpose of this study was to investigate the rate of progression of children and young adults with SCD and albuminuria over time...
  5. pmc Pain and other non-neurological adverse events in children with sickle cell anemia and previous stroke who received hydroxyurea and phlebotomy or chronic transfusions and chelation: results from the SWiTCH clinical trial
    Ofelia Alvarez
    Department of Pediatrics, Division of Pediatric Hematology, University of Miami, Miami, Florida
    Am J Hematol 88:932-8. 2013
    ..In children with SCA and prior stroke, monthly transfusions and daily iron chelation provided superior protection against acute vaso-occlusive pain SAEs when compared to hydroxyurea and monthly phlebotomy...
  6. pmc Impact of hydroxyurea on clinical events in the BABY HUG trial
    Courtney D Thornburg
    Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    Blood 120:4304-10; quiz 4448. 2012
    ..This clinical trial is registered with the National Institutes of Health (NCT00006400, www.clinicaltrials.gov)...
  7. ncbi request reprint Primary renal botryoid rhabdomyosarcoma: diagnosis and outcome
    Juan E Sola
    Pediatric Surgery, University of Miami, Jackson Memorial Medical Center, Miami, FL 33136, USA
    J Pediatr Surg 42:e17-20. 2007
    ..We report on a pediatric patient who, despite having multiple metastases to the lung on presentation, is free of disease 28 months after radical nephrectomy combined with chemotherapy and radiation therapy...
  8. doi request reprint Wilms' tumor, pancreatic islet cell carcinoma, and pheochromocytoma in a child
    Juan E Sola
    Pediatric Surgery, University of Miami, Jackson Memorial Medical Center, Miami, FL 33136, USA
    J Pediatr Surg 43:E25-9. 2008
    ..This case underscores the importance of repeat biopsies in patients with multiple neoplasms to confirm the diagnosis and guide management...
  9. doi request reprint Abnormalities in renal tubular phosphate handling in children with sickle cell disease
    Vimal Master Sankar Raj
    Division of Pediatric Nephrology, University of Miami, Miami, Florida
    Pediatr Blood Cancer 61:2267-70. 2014
    ..Hence, we evaluated parameters of renal tubular phosphorus handling and their relation to prevailing FGF23 levels in a cohort of young SCD patients...
  10. pmc Biomarkers of splenic function in infants with sickle cell anemia: baseline data from the BABY HUG Trial
    Zora R Rogers
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390 9063, USA
    Blood 117:2614-7. 2011
    ..5% or HJB ≥665/10(6). HJB is methodologically advantageous compared with PIT, but both are valid biomarkers of splenic function. This trial was registered at www.clinicaltrials.gov as #NCT00006400...
  11. doi request reprint Adherence to deferasirox in children and adolescents with sickle cell disease during 1-year of therapy
    Ofelia Alvarez
    Department of Pediatrics, Division of Pediatric Hematology Oncology, University of Miami Miller School ofMedicine, Miami, FL 33136, USA
    J Pediatr Hematol Oncol 31:739-44. 2009
    ..Adherence to long-term treatment is challenging. Deferasirox (DFX) is a daily oral iron chelator approved in the United States for transfusional iron overload...
  12. doi request reprint Albuminuria correlates with hemolysis and NAG and KIM-1 in patients with sickle cell anemia
    Dima Hamideh
    Division of Pediatric Hematology D 820, University of Miami, PO Box 016960, Miami, FL, 33101, USA
    Pediatr Nephrol 29:1997-2003. 2014
    ..Although hyperfiltration and albuminuria are common pathological conditions, kidney injury (KI) biomarkers have been seldom studied in individuals with sickle cell anemia (SCA)...
  13. ncbi request reprint Early blood transfusions protect against microalbuminuria in children with sickle cell disease
    Ofelia Alvarez
    Division of Pediatric Hematology, University of Miami, Holtz Children s Hospital, Miami, Florida 33136, USA
    Pediatr Blood Cancer 47:71-6. 2006
    ..Microalbuminuria (MA) is an early indicator for glomerulopathy in sickle cell disease (SCD)...
  14. doi request reprint Quantification of sickle cells in the peripheral smear as a marker of disease severity
    Ofelia Alvarez
    Department of Pediatrics, Mailman Center Child Development, University of Miami, Miami, Florida, USA
    Fetal Pediatr Pathol 34:149-54. 2015
    ..Percent of SC increased with age and correlated with disease severity, especially hemolytic complications, providing readily available information with minimal or no extra cost...
  15. doi request reprint Sickle cell disease related mortality in the United States (1999-2009)
    Dima Hamideh
    Division of Pediatric Hematology, University of Miami Miller School of Medicine, Miami, Florida, USA
    Pediatr Blood Cancer 60:1482-6. 2013
    ..Little is known about the national outcome of children and adults with sickle cell disease (SCD) given contemporary care...
  16. doi request reprint Durable immune response to inactivated H1N1 vaccine is less likely in children with sickle cell anemia receiving chronic transfusions
    Saroj Purohit
    Division of Pediatric Hematology, University of Miami Miller School of Medicine, Miami, FL 33101, USA
    Pediatr Blood Cancer 59:1280-3. 2012
    ..The objective of this study was to assess seroprotective post-vaccine H1N1 antibody response in children with SCD...
  17. pmc Health-related quality of life in children with sickle cell disease: a report from the Comprehensive Sickle Cell Centers Clinical Trial Consortium
    Carlton Dampier
    Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Pediatr Blood Cancer 55:485-94. 2010
    ..0 generic core and fatigue scales...