Genomes and Genes
Melinda C Aldrich
Affiliation: University of California
- Comparison of statistical methods for estimating genetic admixture in a lung cancer study of African Americans and LatinosMelinda C Aldrich
University of California, San Francisco, Box 2911 Rock Hall, Mission Bay 582, 1550 4th Street, San Francisco, CA 94143 2911, USA
Am J Epidemiol 168:1035-46. 2008..Genetic admixture proportions provide a quantitative measure of ancestry differences among Latinos that can be used in analyses of genetic risk factors...
- CYP1A1/2 haplotypes and lung cancer and assessment of confounding by population stratificationMelinda C Aldrich
Department of Medicine and Division of Neuroepidemiology, University of California, San Francisco, California, USA
Cancer Res 69:2340-8. 2009..These results suggest that a variant occurring within the CYP1A2 region may be conferring an increased risk of lung cancer in Latinos...
- Socioeconomic status and lung cancer: unraveling the contribution of genetic admixtureMelinda C Aldrich
at the time of the study, Melinda C Aldrich was with the Division of Epidemiology, School of Public Health, University of California, Berkeley Steve Selvin is with the Division of Biostatistics, School of Public Health, University of California, Berkeley Margaret R Wrensch, Helen M Hansen, and John K Wiencke are with the Department of Neurologic Surgery, University of California, San Francisco Jennette D Sison was with the Department of Neurologic Surgery, University of California, San Francisco Charles P Quesenberry Jr, is with the Division of Research, Kaiser Permanente, Oakland, CA Michael F Seldin is with the Departments of Biological Chemistry and Medicine, University of California, Davis Lisa F Barcellos and Patricia A Buffler are with the Division of Epidemiology, School of Public Health, University of California, Berkeley
Am J Public Health 103:e73-80. 2013..We examined the relationship between genetic ancestry, socioeconomic status (SES), and lung cancer among African Americans and Latinos...
- Nucleotide excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African AmericansJeffrey S Chang
Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA
Int J Cancer 123:2095-104. 2008..61; 95% CI: 0.42-0.88). Our study suggests different elements of the NER pathway may be important in the different ethnic groups resulting either from different linkage relationship, genetic backgrounds and/or exposure histories...
- Genetic variants in the folate pathway and risk of childhood acute lymphoblastic leukemiaCatherine Metayer
School of Public Health, University of California, Berkeley, 1995 University Avenue, Suite 460, Berkeley, CA 94704 7392, USA
Cancer Causes Control 22:1243-58. 2011..We examined whether child's germline genetic variation in the folate pathway is associated with childhood acute lymphoblastic leukemia (ALL), and whether periconception maternal folate and alcohol intake modify the risk...
- Base excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African-AmericansJeffrey S Chang
Department of Epidemiology and Biostatistics, Division of Neuroepidemiology, University of California San Francisco, San Francisco, CA 94143 1215, USA
Carcinogenesis 30:78-87. 2009..This study suggests that there are genetic differences in the association between BER pathway and lung cancer between Latinos and African-Americans...
- Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemiaJeffrey S Chang
Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA
Cancer Epidemiol Biomarkers Prev 19:2152-63. 2010..The lack of immune priming in early childhood may result in abnormal immune responses to infections later in life and increase ALL risk...
- Tobacco smoke exposure and the risk of childhood acute lymphoblastic and myeloid leukemias by cytogenetic subtypeCatherine Metayer
School of Public Health, University of California, 1995 University Avenue, Suite 460, Berkeley, CA94704 7392, USA
Cancer Epidemiol Biomarkers Prev 22:1600-11. 2013....
- Reliability of maternal-reports regarding the use of household pesticides: experience from a case-control study of childhood leukemiaDanna A Slusky
School of Public Health, University of California, Berkeley, CA 94704, USA
Cancer Epidemiol 36:375-80. 2012..The aim of this study is to assess the reliability of self-reported household use of pesticides and potential differences in reliability by case-control status, and by socio-demographic characteristics...
- A meta-analysis identifies new loci associated with body mass index in individuals of African ancestryKeri L Monda
The Center for Observational Research, Amgen, Inc Thousand Oaks, California, USA
Nat Genet 45:690-6. 2013..7 × 10(-7)), five of which reached genome-wide significance. These findings provide strong support for shared BMI loci across populations, as well as for the utility of studying ancestrally diverse populations...
- Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populationsJoshua M Galanter
Department of Medicine, University of California, San Francisco, CA 94143 2911, USA
J Allergy Clin Immunol 128:37-43.e12. 2011..We sought to examine the possibility that population-specific genetic risks contribute to this disparity...
- Cytogenetics of Hispanic and White children with acute lymphoblastic leukemia in CaliforniaMelinda C Aldrich
University of California Berkeley, 2150 Shattuck Avenue, Suite 500, Berkeley, CA 94720 7380, USA
Cancer Epidemiol Biomarkers Prev 15:578-81. 2006..The mechanistic basis for this 2-fold variation in frequency of TEL-AML1 may be due to ethnic-specific risk factors or genetics and should be explored further...