Amir Aghajanian

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif
    Amir Aghajanian
    Department of Cell and Developmental Biology, University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States of America
    PLoS ONE 4:e8045. 2009
  2. pmc Redox regulation of Ras and Rho GTPases: mechanism and function
    Lauren Mitchell
    Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Antioxid Redox Signal 18:250-8. 2013

Collaborators

  • Lauren Mitchell
  • Sharon L Campbell
  • G Aaron Hobbs

Detail Information

Publications2

  1. pmc Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif
    Amir Aghajanian
    Department of Cell and Developmental Biology, University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States of America
    PLoS ONE 4:e8045. 2009
    ..We hypothesized that this redox-based mechanism occurs in cells and affects cytoskeletal dynamics, and in this report we conclude this is indeed a novel mechanism of regulating the GTPase RhoA...
  2. pmc Redox regulation of Ras and Rho GTPases: mechanism and function
    Lauren Mitchell
    Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Antioxid Redox Signal 18:250-8. 2013
    ..We also discuss the debate within the literature regarding whether 2e(-) oxidation mechanisms also regulate Ras GTPase activity...