University of Louisville

Summary

Organization: University of Louisville
Country: USA

Top Publications

  1. doi Virtual journal club connects evidence to practice: an analysis of participant responses
    Carlee Lehna
    School of Nursing, University of Louisville, Louisville, Kentucky 40202, USA
    J Nurs Adm 40:522-8. 2010
  2. doi Patient expectations in facial transplantation
    John H Barker
    Department of Surgery, University of Louisville, Louisville, KY 40202, USA
    Ann Plast Surg 61:68-72. 2008
  3. doi Cystic hypersecretory carcinoma of the breast with paget disease of the nipple: a diagnostic challenge
    Sunati Sahoo
    Department of Pathology, University of Louisville Hospital, Louisville, KY 40202, USA
    Int J Surg Pathol 16:208-12. 2008
  4. ncbi An adaptive ERG technique to measure normal and altered dark adaptation in the mouse
    Paul J DeMarco
    Louisville VA Medical Center, Department of Psychological and Brain Sciences, University of Louisville, 317 Life Sciences Bldg, Louisville, KY, USA
    Doc Ophthalmol 115:155-63. 2007
  5. pmc Systemic inflammation in non-obese children with obstructive sleep apnea
    David Gozal
    Division of Pediatric Sleep Medicine and Kosair Children s Hospital Research Institute, Department of Pediatrics, University of Louisville, 570 South Preston Street, Suite 204, Louisville, KY 40202, USA
    Sleep Med 9:254-9. 2008
  6. ncbi Declining mortality from smoking in the United States
    Brad Rodu
    Department of Medicine, School of Medicine, University of Louisville, Louisville, KY 40202, USA
    Nicotine Tob Res 9:781-4. 2007
  7. pmc The late phase of preconditioning and its natural clinical application--gene therapy
    Roberto Bolli
    Division of Cardiology, University of Louisville, 550 S Jackson Street, ACB, Louisville, KY 40292, USA
    Heart Fail Rev 12:189-99. 2007
  8. pmc Lung ischemia-reperfusion injury: implications of oxidative stress and platelet-arteriolar wall interactions
    Alexander V Ovechkin
    Department of Physiology, School of Medicine University of Louisville, Louisville, Kentucky 40202, USA
    Arch Physiol Biochem 113:1-12. 2007
  9. pmc Mechanisms of immune system activation in glaucoma: oxidative stress-stimulated antigen presentation by the retina and optic nerve head glia
    GULGUN TEZEL
    Department of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Kentucky Lions Eye Center, 301 E Muhammad Ali Boulevard, Louisville, KY 40202, USA
    Invest Ophthalmol Vis Sci 48:705-14. 2007
  10. ncbi Chronic kidney disease
    Eleanor Lederer
    University of Louisville, Kidney Disease Program, Baxter Bldg, Pod 102 South, 570 S Preston St, Louisville, KY 40202, USA
    Am J Kidney Dis 49:162-71. 2007

Research Grants

Detail Information

Publications62

  1. doi Virtual journal club connects evidence to practice: an analysis of participant responses
    Carlee Lehna
    School of Nursing, University of Louisville, Louisville, Kentucky 40202, USA
    J Nurs Adm 40:522-8. 2010
    ..The authors discuss the VJC and the outcomes of an evaluation project...
  2. doi Patient expectations in facial transplantation
    John H Barker
    Department of Surgery, University of Louisville, Louisville, KY 40202, USA
    Ann Plast Surg 61:68-72. 2008
    ..When consulting potential face transplantation patients, surgeons should maintain open communication to assure that their expectations are closely aligned with the realities of the procedure...
  3. doi Cystic hypersecretory carcinoma of the breast with paget disease of the nipple: a diagnostic challenge
    Sunati Sahoo
    Department of Pathology, University of Louisville Hospital, Louisville, KY 40202, USA
    Int J Surg Pathol 16:208-12. 2008
    ..A left simple mastectomy showed a large multicystic lesion occupying most of the lower quadrants by a cystic hypersecretory carcinoma and Paget disease of the nipple...
  4. ncbi An adaptive ERG technique to measure normal and altered dark adaptation in the mouse
    Paul J DeMarco
    Louisville VA Medical Center, Department of Psychological and Brain Sciences, University of Louisville, 317 Life Sciences Bldg, Louisville, KY, USA
    Doc Ophthalmol 115:155-63. 2007
    ..These data demonstrate that this adaptive tracking procedure measures retinal sensitivity and the contributions of the rod and/or cone pathways during dark adaptation in both WT control and mutant mice...
  5. pmc Systemic inflammation in non-obese children with obstructive sleep apnea
    David Gozal
    Division of Pediatric Sleep Medicine and Kosair Children s Hospital Research Institute, Department of Pediatrics, University of Louisville, 570 South Preston Street, Suite 204, Louisville, KY 40202, USA
    Sleep Med 9:254-9. 2008
    ..The changes in levels of pro-inflammatory cytokine IL-6 , and the anti-inflammatory cytokine IL-10, both of which play a major role in atherogenesis, a major consequence of OSA, have not specifically been assessed in pediatric patients...
  6. ncbi Declining mortality from smoking in the United States
    Brad Rodu
    Department of Medicine, School of Medicine, University of Louisville, Louisville, KY 40202, USA
    Nicotine Tob Res 9:781-4. 2007
    ..The impact of smoking on American society will diminish even further in the foreseeable future as smoking prevalence continues its decline among men and women...
  7. pmc The late phase of preconditioning and its natural clinical application--gene therapy
    Roberto Bolli
    Division of Cardiology, University of Louisville, 550 S Jackson Street, ACB, Louisville, KY 40292, USA
    Heart Fail Rev 12:189-99. 2007
    ....
  8. pmc Lung ischemia-reperfusion injury: implications of oxidative stress and platelet-arteriolar wall interactions
    Alexander V Ovechkin
    Department of Physiology, School of Medicine University of Louisville, Louisville, Kentucky 40202, USA
    Arch Physiol Biochem 113:1-12. 2007
    ..This review discusses the relationship between ROS, RNS, P-selectin, and platelet-arteriolar wall interactions and proposes a hypothesis for their role in microvascular responses during pulmonary IR...
  9. pmc Mechanisms of immune system activation in glaucoma: oxidative stress-stimulated antigen presentation by the retina and optic nerve head glia
    GULGUN TEZEL
    Department of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Kentucky Lions Eye Center, 301 E Muhammad Ali Boulevard, Louisville, KY 40202, USA
    Invest Ophthalmol Vis Sci 48:705-14. 2007
    ..This study aimed to determine the in vitro effects of reactive oxygen species (ROS) on the phenotype and antigen-presenting function of the retina and optic nerve head glia...
  10. ncbi Chronic kidney disease
    Eleanor Lederer
    University of Louisville, Kidney Disease Program, Baxter Bldg, Pod 102 South, 570 S Preston St, Louisville, KY 40202, USA
    Am J Kidney Dis 49:162-71. 2007
  11. ncbi Current advances in the surgical approach to abdominal trauma
    Glen A Franklin
    Department of Surgery, University of Louisville School o f Medicine, Louisville, KY 40292, United States
    Injury 37:1143-56. 2006
    ..The authors present their preferred treatment for these three common types of abdominal solid organ injury and present an illustrative case example...
  12. ncbi Controlling multiple-drug-resistant organisms at the hospital level
    Julio A Ramirez
    Division of Infectious Diseases, University of Louisville, 512 South Hancock Street, Carmichael Building, Room 208 D, Louisville, KY 40202, USA
    Expert Opin Pharmacother 7:1449-55. 2006
    ..Without achieving these three goals, hospitals will not be able to control the spread of MDR organisms...
  13. pmc Informational masking of speech in children: auditory-visual integration
    FREDERIC WIGHTMAN
    Heuser Hearing Institute, Department of Psychological and Brain Sciences, University of Louisville, Louisville, Kentucky 40292, USA
    J Acoust Soc Am 119:3940-9. 2006
    ..Audiovisual presentation produced no informational masking release for the youngest children. Across all ages, the benefit of a synchronized video was strongly associated with speechreading ability...
  14. ncbi A thermodynamic signature for drug-DNA binding mode
    Jonathan B Chaires
    James Graham Brown Cancer Center, University of Louisville, 529 S Jackson Street, Louisville, KY 40202, USA
    Arch Biochem Biophys 453:26-31. 2006
    ..The molecular basis of the contrasting thermodynamic signatures for the two binding modes is by no means clear, but the pattern should be of use in categorizing new DNA binding agents...
  15. pmc Gustatory hedonic value: potential function for forebrain control of brainstem taste processing
    Robert F Lundy
    University of Louisville School of Medicine, Department of Anatomical Sciences and Neurobiology, 500 South Preston Street, Louisville, KY 40292, United States
    Neurosci Biobehav Rev 32:1601-6. 2008
    ..This review discusses the current understanding of centrifugal control of taste processing in subcortical gustatory nuclei and the potential role of such modulation in hedonic responding...
  16. doi Pilomatrixoma in an infant: diagnostic challenges of fine-needle aspiration
    Kanyalakshmi Ayyanar
    Department of Pediatric Hematology Oncology, University of Louisville, Kosair Children s Hospital, Louisville, KY 40202, USA
    J Pediatr Hematol Oncol 30:625-7. 2008
    ....
  17. pmc Hormonal regulation of hepatic drug-metabolizing enzyme activity during adolescence
    Mj Kennedy
    Kosair Charities Pediatric Clinical Research Unit, Department of Pediatrics, School of Medicine, University of Louisville, Louisville, Kentucky, USA
    Clin Pharmacol Ther 84:662-73. 2008
    ....
  18. doi Innate immunity as orchestrator of stem cell mobilization
    M Z Ratajczak
    Stem Cell Biology Program at the James Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA
    Leukemia 24:1667-75. 2010
    ..In this review we will present mounting evidence that innate immunity orchestrates this evolutionarily conserved mechanism of HSPC mobilization...
  19. doi The effect of 2.1 T static magnetic field on astrocyte viability and morphology
    Iman Khodarahmi
    Speed School of Engineering, University of Louisville, University of Louisville, Louisville, KY 40292, USA
    Magn Reson Imaging 28:903-9. 2010
    ..No membrane protrusion was observed by fractal analysis. In conclusion, strong static magnetic field at 2.1 T does not significantly affect the viability and morphological properties of rat astrocytes...
  20. pmc MMP-9 gene ablation and TIMP-4 mitigate PAR-1-mediated cardiomyocyte dysfunction: a plausible role of dicer and miRNA
    Paras Kumar Mishra
    Department of Physiology and Biophysics, School of Medicine, University of Louisville, HSC A 1215, 500S Preston Street, Louisville, KY 40202, USA
    Cell Biochem Biophys 57:67-76. 2010
    ..There is selective inhibition of miR-376b and over-expression of miR-1, miR-26a, miR-30d, and miR-181c in MMP-9KO that are implicated in regulation of G-PCR and calcium handling...
  21. doi Amenorrhea and "man hands"
    HENRY BOHLER
    Department of Obstetrics, Gynecology and Women s Health, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Fertil Steril 94:1519-20. 2010
    ..Serum growth hormone and insulin-like growth factor-1 (IGF-1) levels were elevated and a pituitary macroadenoma was found on computerized tomography (CT)...
  22. ncbi History of dose response
    William J Waddell
    Department of Pharmacology and Toxicology, School of Medicine, University of Louisville, KY, USA
    J Toxicol Sci 35:1-8. 2010
    ..Plotting dose on a linear scale distorts the curve for low doses so that any attempt to detect the relationship of dose of carcinogen to carcinogenesis is impossible...
  23. doi Characterization of humoral responses of ovarian cancer patients: antibody subclasses and antigenic components
    Douglas D Taylor
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Women s Health, University of Louisville School of Medicine, Louisville, KY 40292, USA
    Gynecol Oncol 116:213-21. 2010
    ..In contrast, tumor antigen immunorecognition is observed following initial transformation events. Our objective was to characterize humoral antitumor responses in terms of IgG subclasses generated and tumor antigens recognized...
  24. ncbi The pneumonia severity index and the CRB-65 in cancer patients with community-acquired pneumonia
    S Aliberti
    Dipartimento Toraco polmonare e Cardio circolatorio, University of Milan, Milan, Italy
    Int J Tuberc Lung Dis 13:1550-6. 2009
    ..The ability of the pneumonia severity index (PSI) and the CRB-65 to identify patients with low vs. high risk for mortality among cancer patients with CAP has not been evaluated...
  25. doi The potential application of obsessions to reduce compulsions in individuals with obsessive-compulsive disorder
    Jonathan R Scarff
    Department of Psychiatry and Behavioral Sciences, University of Louisville, Suite 340, Louisville, KY 40202, USA
    Med Hypotheses 74:216-8. 2010
    ....
  26. doi A topographic study of minicolumnar core width by lamina comparison between autistic subjects and controls: possible minicolumnar disruption due to an anatomical element in-common to multiple laminae
    Manuel F Casanova
    Department of Psychiatry and Behavioral Sciences, University of Louisville, Louisville, KY, USA
    Brain Pathol 20:451-8. 2010
    ..In this article we discuss the possible role of double bouquet and pyramidal cells in the translaminar minicolumnar width narrowing observed in autistic subjects...
  27. doi Curriculum resource use and relationships with educational outcomes in an online curriculum
    Charles R Woods
    Division of Pediatric Infectious Diseases, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Acad Med 84:1250-8. 2009
    ..Web-based continuing education (CE) offerings have increased dramatically, yet educators know little about factors influencing resource use within online curricula or relationships between resource use and educational outcomes...
  28. pmc Hydrogen sulfide ameliorates hyperhomocysteinemia-associated chronic renal failure
    Utpal Sen
    Dept of Physiology and Biophysics, Univ of Louisville School of Medicine, 500 S Preston St, Louisville, KY 40202, USA
    Am J Physiol Renal Physiol 297:F410-9. 2009
    ..Additionally, here we demonstrate with evidence that H(2)S supplementation prevents HHcy-associated renal damage, in part, through its antioxidant properties...
  29. doi Undressing "health fashion": an examination of health-cause clothing and accessories
    Kandi L Walker
    Department of Communication, School of Public Health and Information Sciences, University of Louisville, Louisville, KY 40292, USA
    Health Promot Pract 11:665-74. 2010
    ..In this article, the authors explore recent interest in "health fashion," examining in particular its origins, effectiveness, and implications...
  30. ncbi The role of membrane complement regulatory proteins in cancer immunotherapy
    Jun Yan
    Tumor Immunobiology Program of the James Graham Brown Cancer Center, Department of Medicine, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Adv Exp Med Biol 632:159-74. 2008
    ..Strategies have been developed to address these issues and more in vivo studies are needed to further validate these combination approaches...
  31. ncbi Improving methods of assessing natural killer cell cytotoxicity
    Sandra E Sephton
    Department of Psychological and Brain Sciences and James Graham Brown Cancer Center, University of Louisville, Kentucky 40202, USA
    Int J Methods Psychiatr Res 15:12-21. 2006
    ..Examples of these interpretation methods are presented using NK cytotoxicity data from a group of metastatic breast cancer patients. This approach will be useful in applications of NK cell measurement in psychoneuroimmunology research...
  32. ncbi Oxidant stress and inflammation in the snoring child: confluent pathways to upper airway pathogenesis and end-organ morbidity
    David Gozal
    Division of Pediatric Sleep Medicine, Department of Pediatrics, Kosair Children s Hospital Research Institute, University of Louisville, 570 S Preston Street, Suite 321, Louisville, KY 40202, USA
    Sleep Med Rev 10:83-96. 2006
    ..This hypothetical working model incorporates both dose-dependent disease severity components, as well as environmental and genetic elements of susceptibility...
  33. ncbi Developmental field defects: coming together of associations and sequences during blastogenesis
    Joseph H Hersh
    Weisskopf Center for the Evaluation of Children, Department of Pediatrics, University of Louisville, Louisville, Kentucky 40202, USA
    Am J Med Genet 110:320-3. 2002
    ....
  34. ncbi The Eden Alternative: findings after 1 year of implementation
    Mary Thoesen Coleman
    Department of Family and Community Medicine, University of Louisville School of Medicine, Kentucky 40202, USA
    J Gerontol A Biol Sci Med Sci 57:M422-7. 2002
    ..This study examines the effects of the Eden Alternative (EA), a systematic introduction of pets, plants, and children into a nursing home, on the quality of life of nursing home residents...
  35. pmc Eavesdropping on visual cues in green swordtail (Xiphophorus helleri) fights: a case for networking
    Ryan L Earley
    Department of Biology, Life Science, Room 139, University of Louisville, Louisville, KY 40292, USA
    Proc Biol Sci 269:943-52. 2002
    ..Our data lend clear support for the importance of eavesdropping in visually based aggressive signalling systems...
  36. ncbi Comparison of microtransducer and fiberoptic catheters for urodynamic studies
    P J Culligan
    Evanston Continence Center, Division of Urogynecology and Reconstructive Pelvic Surgery, Northwestern University Medical School, Evanston Northwestern Healthcare, Evanston, Illinois, USA
    Obstet Gynecol 98:253-7. 2001
    ..To assess the validity and reproducibility of a fiberoptic transducer urodynamic catheter for urethral closure pressure profiles and leak point pressure determination, using a microtransducer catheter as the standard...
  37. ncbi Dissecting the energy needs of the body
    S A McClave
    Department of Medicine, University of Louisville School of Medicine, 550 South Jackson Street, Louisville, Kentucky 40292, USA
    Curr Opin Clin Nutr Metab Care 4:143-7. 2001
    ..Recently reported studies have served mainly to reinforce concepts described previously, and clarify some areas of controversy...
  38. ncbi Right-sided aorta: a cadaver report and brief discussion of human aortic arch anomalies
    K P Bhatnagar
    Department of Anatomical Sciences and Neurobiology, Health Sciences Center, University of Louisville, School of Medicine, KY 40292, USA
    Ann Anat 182:559-62. 2000
    ..The large veins of the thorax and the other thoracic organs appeared normal...
  39. ncbi Transverse retubularized ileovesicostomy continent urinary diversion to the umbilicus
    J G Van Savage
    Department of Surgery, University of Louisville School of Medicine, Kentucky 40292, USA
    Tech Urol 6:29-33. 2000
    ..When the Mitrofanoff appendicovesicostomy continent urinary diversion is not an option, the transverse retubularized ileovesicostomy has several advantages as a second choice...
  40. ncbi Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms
    D W Hein
    Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Kentucky 40292, USA
    Cancer Epidemiol Biomarkers Prev 9:29-42. 2000
    ....
  41. ncbi Parametric cure models of relative and cause-specific survival for grouped survival times
    J W Gamel
    Veterans Administration Hospital and University of Louisville School of Medicine, KY 40292, USA
    Comput Methods Programs Biomed 61:99-110. 2000
    ..Current software does not provide the flexibility of this unified approach...
  42. ncbi Role of estrogen receptor ligand and estrogen response element sequence on interaction with chicken ovalbumin upstream promoter transcription factor (COUP-TF)
    C M Klinge
    Department of Biochemistry and Molecular Biology, University of Louisville School of Medicine, KY 40292, USA
    J Steroid Biochem Mol Biol 71:1-19. 1999
    ..We suggest that COUP-TFI plays a role in mitigating estrogen-responsive gene expression...
  43. ncbi The role of RXR-alpha in retinoic acid-induced cleft palate as assessed with the RXR-alpha knockout mouse
    P Nugent
    Department of Molecular, Cellular and Craniofacial Biology, University of Louisville School of Dentistry and University of Louisville Birth Defects Center, KY 40292, USA
    Int J Dev Biol 43:567-70. 1999
    ..Treatment of RXR-alpha knockout mice with a teratogenic dose of RA on gestation day 11 or 12 induces cleft palate at a lower frequency than that seen in wild-type animals...
  44. ncbi Photodynamic therapy for palliation of chest wall recurrence in patients with breast cancer
    S W Taber
    Department of Surgery, University of Louisville, Kentucky 40202, USA
    J Surg Oncol 68:209-14. 1998
    ..Photodynamic therapy (PDT) is a new modality that uses a photosensitizer and light to destroy tumor cells selectively. We report here our experience with PDT as a treatment for chest wall recurrence...
  45. ncbi Halo pin loosening: a biomechanical comparison of experimental and conventional designs
    M J Voor
    Orthopaedic Bioengineering Laboratory, University of Louisville Department of Orthopaedic Surgery, KY 40292, USA
    J Biomech 31:397-400. 1998
    ..These characteristics may translate into fewer complications in the clinical setting...
  46. ncbi Multi-modality neurophysiologic monitoring for cardiac surgery
    Harvey L Edmonds
    Department of Anesthesiology, University of Louisville, Louisville, KY 40202 3617, USA
    Heart Surg Forum 5:225-8. 2002
    ....
  47. ncbi The multidisciplinary approach to develop artificial organs
    Elias Klein
    Kidney Disease Program and Kentucky Proteomics Training Facility, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Blood Purif 21:305-17. 2003
    ..Lengthy delays occurred in artificial organ development when such interdisciplinary collaborations did not take place...
  48. ncbi Adaptive tracking for pneumatic muscle actuators in bicep and tricep configurations
    John H Lilly
    Department of Electrical and Computer Engineering, University of Louisville, Louisville, KY 40292, USA
    IEEE Trans Neural Syst Rehabil Eng 11:333-9. 2003
    ..Stability results are derived, and the results of simulation studies are presented, contrasting the nonlinear adaptive control to a nonadaptive PID control approach...
  49. ncbi Intrarenal supernumerary ovary excised with partial nephrectomy
    Katherine Hartigan
    Department of Surgery, University of Louisville School of Medicine, Louisville, Kentucky 40206, USA
    Urology 67:424.e11-424.e12. 2006
    ..This report documents the rare anomaly of ectopic ovarian tissue and highlights the extraordinary combination of intrarenal location, lesion complexity, and surgical management with partial nephrectomy that makes this case unique...
  50. ncbi Probing interactions between the coagulants thrombin, Factor XIII, and fibrin(ogen)
    Muriel C Maurer
    Department of Chemistry, University of Louisville, 2320 South Brook Street, Louisville, KY 40292, USA
    Arch Biochem Biophys 445:36-45. 2006
    ..This system of thrombin exosite interactions with differing affinities promotes efficient clot formation...
  51. ncbi Impact of cognitive impairment on the phenomenology of geriatric depression
    Benjamin T Mast
    Dept of Psychological and Brain Sciences, Univ of Louisville, 317 Life Sciences Bldg, Louisville, KY 40292, USA
    Am J Geriatr Psychiatry 13:694-700. 2005
    ....
  52. ncbi Ascending aorta outflow graft location and pulsatile ventricular assist provide optimal hemodynamic support in an adult mock circulation
    Kenneth N Litwak
    Jewish Hospital Heart and Lung Institute, University of Louisville, Department of Surgery, Louisville KY 40202, USA
    Artif Organs 29:629-35. 2005
    ..The long-term implications of these findings are being examined in ongoing studies...
  53. ncbi Married to the boss, or how checking the box changed my life
    Susan Galandiuk
    Department of Surgery, University of Louisville, Louisville, KY 40292, USA
    Am J Surg 190:300-4. 2005
  54. ncbi At issue: Sex and gender in schizophrenia
    Rich Lewine
    Department of Psychological and Brain Sciences, University of Louisville, Louisville, KY 40292, USA
    Schizophr Bull 30:755-62. 2004
    ....
  55. ncbi Self-control, deviant peers, and software piracy
    George E Higgins
    University of Louisville, Department of Justice Administration, Louisville, KY 40292, USA
    Psychol Rep 95:921-31. 2004
    ..Analysis indicated differential links for lack of moral attitude in relation to software piracy and favorable attitudes for software piracy for varying association with deviant peers...
  56. ncbi Prolonged local neurotrophin-3 infusion reduces ipsilateral collateral sprouting of spared corticospinal axons in adult rats
    T Hagg
    Department of Neurological Surgery, Kentucky Spinal Cord Injury Research Center, 511 South Floyd Street, MDR Room 616, University of Louisville, Louisville, KY 40292, USA
    Neuroscience 130:875-87. 2005
    ..They identify an unexpected context-dependent outgrowth inhibitory effect of NT-3...
  57. ncbi Auditory cortical projections to the cochlear nucleus in guinea pigs
    Brett R Schofield
    Department of Anatomical Sciences and Neurobiology, University of Louisville, 500 S Preston Street, Louisville, KY 40202, USA
    Hear Res 199:89-102. 2005
    ..The results illustrate direct cortical projections to the cochlear nucleus that are likely to modulate the activity in a number of ascending auditory pathways...
  58. ncbi Mild sustained and intermittent hypoxia induce apoptosis in PC-12 cells via different mechanisms
    Evelyne Gozal
    Kosair Children s Hospital Research Institute, Department of Pediatrics, University of Louisville, 570 South Preston St, Suite 321, Louisville, KY 40202, USA
    Am J Physiol Cell Physiol 288:C535-42. 2005
    ....
  59. ncbi Cerebral oximetry for cardiac and vascular surgery
    Harvey L Edmonds
    Department of Anesthesiology and Perioperative Medicine, University of Louisville School of Medicine, Louisville, Kentucky 40202 3619, USA
    Semin Cardiothorac Vasc Anesth 8:147-66. 2004
    ..Our goals are to clarify common misconceptions about near-infrared spectroscopy and acquaint the reader with the substantial literature that now supports cerebral oximetric monitoring in cardiac and major vascular surgery...
  60. ncbi Analysis of thresholds for carcinogenicity
    William J Waddell
    Department of Pharmacology and Toxicology, School of Medicine, University of Louisville, 14300 Rose Wycombe Lane, Prospect, KY 40059, USA
    Toxicol Lett 149:415-9. 2004
    ..The animal studies should be viewed as providing evidence for the safety of these flavors and other compounds at current levels of human exposure...
  61. ncbi Sentinel lymph node biopsy for melanoma of the head and neck
    Eric J Lentsch
    Division of Otolaryngology, Head and Neck Surgery, University of Louisville, KY 40292, USA
    Expert Rev Anticancer Ther 3:673-83. 2003
    ..For these reasons, the authors believe that SLNB will become the standard-of-care for head and neck melanoma as well as for other body sites...
  62. ncbi Cooperation among unrelated individuals: reciprocal altruism, by-product mutualism and group selection in fishes
    L A Dugatkin
    Division of Biological Sciences, University of Missouri, Columbia 65211, USA
    Biosystems 37:19-30. 1996
    ....

Research Grants62

  1. Novel hematopoietic effects of C3 cleavage fragments
    Mariusz Z Ratajczak; Fiscal Year: 2010
    ..We will test the hypothesis that this defect is related to the lack of naturally occurring C cascade-activating IgM antibodies. ..
  2. Novel hematopoietic effects of C3 cleavage fragments
    Mariusz Ratajczak; Fiscal Year: 2007
    ..We will test the hypothesis that this defect is related to the lack of naturally occurring C cascade-activating IgM antibodies. ..
  3. The CXCR4-SDF-1 Axis in Metastatic Rhabdomyosarcoma
    Mariusz Ratajczak; Fiscal Year: 2009
    ..This work will be of relevance for designing strategies to block the SDF-1-CXCR4 axis to treat CXCR4-positive cancers. ..
  4. CELLULAR AND MOLECULAR BASIS OF HIV BASED THROMBOCYTOPEN
    Mariusz Ratajczak; Fiscal Year: 2002
    ..In toto, the studies proposed in this grant will increase the knowledge about pathogenesis of AIDS associated thrombocytopenia and may lead to development of new strategies for its treatment of prevention. (End of Abstract) ..
  5. Normal Human and Schizophrenic Brain
    Manuel Casanova; Fiscal Year: 2004
    ..Another possible outcome is that the number of minicolumns in the temporal lobe may differ without a concomitant change in the structural reorganization. ..
  6. Building a Selective Inhibitory Control Tone in Autism: An rTMS Study
    Manuel F Casanova; Fiscal Year: 2010
    ..The proposal represents a new development in combining TMS with functional outcome measures (cognitive ERP, EEG), using TMS as a theory-guided psychiatric therapy in autism. ..
  7. Modular Abnormalities of Brain Organization in Autism
    Manuel Casanova; Fiscal Year: 2007
    ..Treatment modalities, especially neuropharmaceutical agents, will prove more specific as their targets are better understood. ..
  8. Gross morphological correlates to the minicolumnopathy of autism
    Manuel F Casanova; Fiscal Year: 2010
    ..The intent is to develop markers of the condition that can be detected while the patient is alive. Another innovative aspect of the proposal is an attempt to validate current diagnostic screening techniques against autopsy findings. ..
  9. Reduced Interneuronal Space in Schizophrenic Brains
    Manuel Casanova; Fiscal Year: 2005
    ..If our preliminary findings are corroborated, the smaller than normal minicolumns will demonstrate a reorganization of brain circuitry most probably defined during development. ..
  10. DNA SEQUENCES IMPACT ESTROGEN AND ANTIESTROGEN ACTIVITY
    Carolyn M Klinge; Fiscal Year: 2010
    ....
  11. DNA SEQUENCES IMPACT ESTROGEN AND ANTIESTROGEN ACTIVITY
    CAROLYN KLINGE; Fiscal Year: 2009
    ....
  12. Regulation of miRNA in breast cancer
    Carolyn M Klinge; Fiscal Year: 2010
    ....
  13. DNA SEQUENCES IMPACT ESTROGEN AND ANTIESTROGEN ACTIVITY
    Carolyn M Klinge; Fiscal Year: 2010
    ....
  14. TNF-alpha in cell death & neuroprotection in glaucoma
    GULGUN TEZEL; Fiscal Year: 2010
    ....
  15. Proteomic Analysis of Retinal Ganglion Cell Death in Glaucoma
    GULGUN TEZEL; Fiscal Year: 2010
    ..These studies are expected to provide comprehensive information about the nerve cell death process, thereby allowing new treatment possibilities for 3 million Americans suffering from glaucoma. ..
  16. DNA SEQUENCES IMPACT ESTROGEN AND ANTIESTROGEN ACTIVITY
    CAROLYN KLINGE; Fiscal Year: 2009
    ....
  17. TNF-alpha in cell death & neuroprotection in glaucoma
    GULGUN TEZEL; Fiscal Year: 2009
    ....
  18. DNA SEQUENCES IMPACT ESTROGEN AND ANTIESTROGEN ACTIVITY
    CAROLYN KLINGE; Fiscal Year: 2002
    ....
  19. TNF-alpha in cell death & neuroprotection in glaucoma
    GULGUN TEZEL; Fiscal Year: 2007
    ....
  20. Regulation of miRNA expression in breast cancer cells
    CAROLYN KLINGE; Fiscal Year: 2007
    ..It is our long term hope that miRNAs may provide novel biomarkers and new insights into the mechanisms by which breast tumors gain TAM/antiestrogen-resistance and become invasive and metastatic. ..
  21. Summer Endocrine Research Training Program
    CAROLYN KLINGE; Fiscal Year: 2007
    ..Over the past 6 years the University of Louisville has increased its commitment to health science research and infrastructure, graduate education, and ..
  22. TNF-alpha in cell death & neuroprotection in glaucoma
    GULGUN TEZEL; Fiscal Year: 2006
    ..abstract_text> ..
  23. DNA SEQUENCES IMPACT ESTROGEN AND ANTIESTROGEN ACTIVITY
    CAROLYN KLINGE; Fiscal Year: 2006
    ..Results will define the molecular mechanisms of ERalpha, ERbeta, and ERalpha/beta heterodimers as transcriptional regulators, with emphasis on the action of antiestrogens. ..