University of Kansas Medical Center

Summary

Organization: University of Kansas Medical Center
Country: USA

Top Publications

  1. doi Rapid quetiapine loading in youths with bipolar disorder
    Russell E Scheffer
    Department of Psychiatry, University of Kansas School of Medicine Wichita, Wichita, Kansas 67214, USA
    J Child Adolesc Psychopharmacol 20:441-5. 2010
  2. ncbi HIT plants SEEDS in healthcare education
    Helen Connors
    University of Kansas School of Nursing, KU Center for Healthcare Informatics, Kansas City, Kansas 66160, USA
    Nurs Adm Q 31:129-33. 2007
  3. ncbi Complete genomes for hepatitis C virus subtypes 6f, 6i, 6j and 6m: viral genetic diversity among Thai blood donors and infected spouses
    Ling Lu
    Division of Gastroenterology Hepatology, Department of Medicine, University of Kansas Medical Center, 4035 Delp, MS 1023, Kansas City, KS 66160, USA
    J Gen Virol 88:1505-18. 2007
  4. ncbi Altered transit and bacterial overgrowth in the cystic fibrosis mouse small intestine
    Robert C De Lisle
    Department of Anatomy and Cell Biology, University of Kansas School of Medicine, Kansas City, KS 66160, USA
    Am J Physiol Gastrointest Liver Physiol 293:G104-11. 2007
  5. pmc Gastroparesis secondary to a demyelinating disease: a case series
    Savio C Reddymasu
    Department of Medicine, Kansas University Medical Center, Kansas City, KS, USA
    BMC Gastroenterol 7:3. 2007
  6. ncbi Mammographic density: use in risk assessment and as a biomarker in prevention trials
    Carol J Fabian
    Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA
    J Nutr 136:2705S-8S. 2006
  7. ncbi N-cadherin signaling in synapse formation and neuronal physiology
    JUAN L BRUSES
    Department of Anatomy and Cell Biology, Kansas University Medical Center, Kansas City, KS, USA
    Mol Neurobiol 33:237-52. 2006
  8. ncbi Immunoprophylaxis against AIDS in macaques with a lentiviral DNA vaccine
    Zhenqian Liu
    Marion Merrell Dow Laboratory of Viral Pathogenesis, Department of Microbiology, Molecular Genetics and Immunology, The University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA
    Virology 351:444-54. 2006
  9. pmc Case-based exercises fail to improve medical students' information management skills: a controlled trial
    Heidi S Chumley
    Department of Family Medicine, University of Kansas School of Medicine, Kansas City, USA
    BMC Med Educ 6:14. 2006
  10. ncbi Bayesian sample size calculations in phase II clinical trials using a mixture of informative priors
    Byron J Gajewski
    Schools of Allied Health and Nursing, Center for Biostatistics and Advanced Informatics, The University of Kansas Medical Center, Kansas City, 66160, USA
    Stat Med 25:2554-66. 2006

Detail Information

Publications62

  1. doi Rapid quetiapine loading in youths with bipolar disorder
    Russell E Scheffer
    Department of Psychiatry, University of Kansas School of Medicine Wichita, Wichita, Kansas 67214, USA
    J Child Adolesc Psychopharmacol 20:441-5. 2010
    ..The aim of this study was to evaluate the tolerability and efficacy of rapid quetiapine loading in youth diagnosed with pediatric bipolar disorder (PBD)...
  2. ncbi HIT plants SEEDS in healthcare education
    Helen Connors
    University of Kansas School of Nursing, KU Center for Healthcare Informatics, Kansas City, Kansas 66160, USA
    Nurs Adm Q 31:129-33. 2007
    ..It results in IT savvy healthcare providers who will cross the quality chasm...
  3. ncbi Complete genomes for hepatitis C virus subtypes 6f, 6i, 6j and 6m: viral genetic diversity among Thai blood donors and infected spouses
    Ling Lu
    Division of Gastroenterology Hepatology, Department of Medicine, University of Kansas Medical Center, 4035 Delp, MS 1023, Kansas City, KS 66160, USA
    J Gen Virol 88:1505-18. 2007
    ..3 to 100%. The similarities of the complete genome sequences from the two couples in the current study are consistent with HCV transmission between spouses...
  4. ncbi Altered transit and bacterial overgrowth in the cystic fibrosis mouse small intestine
    Robert C De Lisle
    Department of Anatomy and Cell Biology, University of Kansas School of Medicine, Kansas City, KS 66160, USA
    Am J Physiol Gastrointest Liver Physiol 293:G104-11. 2007
    ..In conclusion, small intestinal transit was significantly slower in CF mice, and this is likely a major factor in SIBO in CF...
  5. pmc Gastroparesis secondary to a demyelinating disease: a case series
    Savio C Reddymasu
    Department of Medicine, Kansas University Medical Center, Kansas City, KS, USA
    BMC Gastroenterol 7:3. 2007
    ..Gastroparesis secondary to a demyelinating disease of the brain is unusual...
  6. ncbi Mammographic density: use in risk assessment and as a biomarker in prevention trials
    Carol J Fabian
    Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA
    J Nutr 136:2705S-8S. 2006
  7. ncbi N-cadherin signaling in synapse formation and neuronal physiology
    JUAN L BRUSES
    Department of Anatomy and Cell Biology, Kansas University Medical Center, Kansas City, KS, USA
    Mol Neurobiol 33:237-52. 2006
    ..This article focuses on the roles that N-cadherin might play at the level of the synapse through its effect on adhesion and signaling in the proximity of the synaptic junction...
  8. ncbi Immunoprophylaxis against AIDS in macaques with a lentiviral DNA vaccine
    Zhenqian Liu
    Marion Merrell Dow Laboratory of Viral Pathogenesis, Department of Microbiology, Molecular Genetics and Immunology, The University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA
    Virology 351:444-54. 2006
    ..The DNA vaccine induced broad-based protection without using viral proteins to boost the immunity...
  9. pmc Case-based exercises fail to improve medical students' information management skills: a controlled trial
    Heidi S Chumley
    Department of Family Medicine, University of Kansas School of Medicine, Kansas City, USA
    BMC Med Educ 6:14. 2006
    ..Tomorrow's physicians must learn to access, retrieve, integrate and apply current information into ambulatory patient encounters, yet few medical schools teach 'real time' information management...
  10. ncbi Bayesian sample size calculations in phase II clinical trials using a mixture of informative priors
    Byron J Gajewski
    Schools of Allied Health and Nursing, Center for Biostatistics and Advanced Informatics, The University of Kansas Medical Center, Kansas City, 66160, USA
    Stat Med 25:2554-66. 2006
    ..We discuss the theoretical framework for these types of Bayesian designs and show that the Bayesian designs in this paper approximate this theoretical framework...
  11. ncbi Psychometric properties of the Grandparent Perceptions of Family Scale (GPFS)
    Veronica F Rempusheski
    The University of Kansas School of Nursing, Kansas City, KS 66160, USA
    Nurs Res 54:363-71. 2005
    ..For the majority of grandparents, rarely are their perceptions of family assessed, acknowledged, or viewed in the context of potential effect on individual and family health...
  12. ncbi Recurrent pleomorphic adenoma of the parotid gland
    John P Leonetti
    Loyola Center for Cranial Base Surgery, Maywood, IL 60153, USA
    Otolaryngol Head Neck Surg 133:319-22. 2005
    ..To assess the long-term results in the management of 42 patients with recurrent pleomorphic adenoma of the parotid gland...
  13. ncbi Defecation disorders after surgery for Hirschsprung's disease
    Paul E Hyman
    University of Kansas Medical Center, Kansas City, USA
    J Pediatr Gastroenterol Nutr 41:S62-3. 2005
  14. ncbi Heart failure drug utilization patterns for Medicaid patients before and after a heart failure-related hospitalization
    Patricia A Howard
    Department of Pharmacy Practice, University of Kansas School of Pharmacy, University Medical Center, 3901 Rainbow Boulevard, Lawrence, KS 66160 7231, USA
    Congest Heart Fail 11:124-8. 2005
    ..ACE inhibitors and vasodilator use remained constant. ACE-inhibitor doses were below target ranges before and after hospitalization. In this Medicaid cohort, HF-related hospitalizations did not lead to improved HF therapy...
  15. ncbi Intramedullary leiomyolipoma of the thoracic spine. Case report
    Paul M Arnold
    Department of Neurosurgery, University of Kansas School of Medicine, Kansas City, Kansas 66160, USA
    J Neurosurg Spine 6:438-40. 2007
    ..The histological characteristics and location of the neoplasm are unique, and the presentation, surgical management, and pathological characteristics of the lesion are discussed...
  16. ncbi No simple sore throat
    William J Salyers
    Department of Internal Medicine, University of Kansas School of Medicine Wichita, KS 67214, USA
    Am J Med 120:860-2. 2007
  17. ncbi Weight maintenance, behaviors and barriers among previous participants of a university-based weight control program
    C A Befort
    Department of Preventive Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA
    Int J Obes (Lond) 32:519-26. 2008
    ..To examine weight loss maintenance among previous participants of a university-based behavioral weight management program and to compare behavioral strategies and perceived barriers between successful and unsuccessful maintainers...
  18. doi Near-infrared spectroscopy measurement of sacral tissue oxygen saturation in healthy volunteers immobilized on rigid spine boards
    GINA BERG
    The Department of Preventive Medicine and Public Health, University of Kansas School of Medicine Wichita, Wichita, KS 67214, USA
    Prehosp Emerg Care 14:419-24. 2010
    ..The purpose of this research was to study the effects of prolonged spinal immobilization on an RSB on sacral tissue oxygenation of healthy volunteers...
  19. pmc Hypoxia stimulates hepatocyte epithelial to mesenchymal transition by hypoxia-inducible factor and transforming growth factor-beta-dependent mechanisms
    Bryan L Copple
    Department of Pharmacology, Toxicology, and Experimental Therapeutics, University of Kansas Medical Center, Kansas City, KS, USA
    Liver Int 30:669-82. 2010
    ..Our recent studies demonstrated that HIF-1alpha is important for the development of liver fibrosis. Accordingly, the hypothesis was tested that hypoxia stimulates hepatocyte EMT by a HIF-dependent mechanism...
  20. doi Developmental disabilities: effects on well siblings
    Phoebe Dauz Williams
    University of Kansas School of Nursing, Kansas City, Kansas 66160, USA
    Issues Compr Pediatr Nurs 33:39-55. 2010
    ..Forty studies performed between 1970 and 1995 indicated that 60% of parents with children with developmental disabilities reported manifestations of increased risk or negative effects on the well siblings...
  21. doi Time to re-think: ovarian tissue transplantation versus whole ovary transplantation
    S Samuel Kim
    Division of Reproductive Endocrinology and Infertility, Department of Ob Gyn, School of Medicine, University of Kansas, Kansas City, KS, USA
    Reprod Biomed Online 20:171-4. 2010
    ..The safety and efficacy of the new procedure should be proven before any further clinical applications take place. Nevertheless, research on whole ovary cryopreservation should not be discouraged...
  22. pmc An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ
    Fariba Behbod
    Department of Pathology and Laboratory Medicine, The University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA
    Breast Cancer Res 11:R66. 2009
    ..The resulting models, which mimicked some of the diversity of human noninvasive breast cancers in vivo, were used to show whether subtypes of human DCIS might contain distinct subpopulations of tumor-initiating cells...
  23. doi Pediatric emergency preparedness training: are we on a path toward national dissemination?
    Elizabeth Ablah
    Department of Preventive Medicine and Public Health, University of Kansas School of Medicine Wichita, Wichita, KS 67214 3199, USA
    J Trauma 67:S152-8. 2009
    ..Before a standardized, nationally disseminated pediatric curriculum can be developed or endorsed, evidence-based evaluations of short- and long-term outcomes need to be conducted...
  24. doi Perspectives on research among Kansas County health department administrators
    Christie A Befort
    University of Kansas Medical Center, Department of Preventive Medicine and Public Health, Kansas City, KS 66160, USA
    J Public Health Manag Pract 15:E9-15. 2009
    ..Findings have implications for strategies to engage LHDs in academic collaborations such as targeting research projects to fill an existing need identified by LHD staff...
  25. doi Distribution of male infertility specialists in relation to the male population and assisted reproductive technology centers in the United States
    Ajay K Nangia
    Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
    Fertil Steril 94:599-609. 2010
    ..To describe the spatial distribution of assisted reproductive technology (ART) centers and male infertility specialists by location, driving distance from ART center, and potential male population in need of these resources...
  26. pmc Combined effects of scaffold stiffening and mechanical preconditioning cycles on construct biomechanics, gene expression, and tendon repair biomechanics
    Victor Sanjit Nirmalanandhan
    Office of Therapeutics, Discovery and Development, University of Kansas Medical Center, Kansas City, Kansas, USA
    Tissue Eng Part A 15:2103-2111. 2009
    ..Our findings emphasize the importance of properly preconditioning a scaffold to better control/modulate MSC differentiation in vitro and to further enhance repair outcome in vivo...
  27. ncbi Assisted living and the aging trajectory
    Kristine N Williams
    University of Kansas School of Nursing, 3901 Rainbow Blvd, Kansas City, KS 66160 7502, USA
    J Women Aging 20:309-27. 2008
    ..Given the expanded lifespan and growing popularity of AL, it is becoming a new stage in the trajectory of women's aging...
  28. ncbi Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family
    B Hagenbuch
    The University of Kansas Medical Center, Pharmacology, Toxicology and Therapeutics, Kansas City, KS 66160, USA
    Xenobiotica 38:778-801. 2008
    ..4. Finally, some open questions are raised that need to be addressed to advance OATP research in the near future...
  29. pmc Pediatric obesity attitudes, services, and information among rural parents: a qualitative study
    Ann McGrath Davis
    University of Kansas Medical Center, Kansas City, Kansas, USA
    Obesity (Silver Spring) 16:2133-40. 2008
    ..Rural families of overweight children encounter many barriers to healthier living, some of which are unique to their rural status...
  30. ncbi Reciprocal professionalism?
    Anne Walling
    Department of Family and Community Medicine, University of Kansas Wichita, Wichita, KS 67214, USA
    Fam Med 40:352-3. 2008
  31. pmc Deranged aortic intima-media thickness, plasma triglycerides and granulopoiesis in Sl/Sl(d) mice
    Kottarappat N Dileepan
    Division of Allergy, Clinical Immunology and Rheumatology, Department of Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA
    Mediators Inflamm 13:335-41. 2004
    ..Interestingly, the high-fat diet regimen elevated leukocyte counts and the number of monocytes and granulocytes in Sl/Sl(d) mice...
  32. ncbi Eplerenone: a selective aldosterone receptor antagonist for patients with heart failure
    Brian J Barnes
    Department of Pharmacy Practice, University of Kansas Medical Center, Kansas City, KS 6610 7231, USA
    Ann Pharmacother 39:68-76. 2005
    ..To evaluate the pharmacology, pharmacokinetics, safety, and clinical use of eplerenone in heart failure (HF)...
  33. ncbi Soman-induced seizures: limbic activity, oxidative stress and neuroprotective proteins
    T L Pazdernik
    Ralph L Smith Research Center, University of Kansas Medical Center, Kansas City, KS 66160, USA
    J Appl Toxicol 21:S87-94. 2001
    ..These findings suggest that delocalization of iron may catalyze Fenton-like reactions, causing progressive cellular damage via free radical products...
  34. ncbi C-reactive protein and other markers of inflammation among patients undergoing HELP LDL apheresis
    P M Moriarty
    Lipid, Atherosclerosis, and Metabolic Clinic, 3901 Rainbow Boulevard, 1336 KU Hospital, Kansas City, KS 66160 7374, USA
    Atherosclerosis 158:495-8. 2001
    ..After 6 months of therapy, pre-treatment hsCRP showed an overall mean level decrease of 49%. Preliminary results indicate that LDL apheresis results in a rapid and long-term decrease of serum hsCRP levels...
  35. ncbi Fertilization of sea urchin eggs and sperm motility are negatively impacted under low hypergravitational forces significant to space flight
    J S Tash
    Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Biol Reprod 65:1224-31. 2001
    ..Thus, more detailed studies on the impact of space flight on development should include studies of sperm function and fertilization...
  36. ncbi The effect of hamstring muscle compensation for anterior laxity in the ACL-deficient knee during gait
    W Liu
    Department of Physical Therapy Education University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, USA
    J Biomech 33:871-9. 2000
    ..The consequences of increased hamstring muscle force included increased quadriceps muscle force and joint contact force...
  37. ncbi Correlation of the bovine cervical mucus penetration test with human sperm characterisitics in 1,406 ejaculates
    B A Keel
    Women s Research Institute, Department of Obstetrics Gynecology, University of Kansas School of Medicine Wichita 67214, USA
    Arch Androl 44:109-15. 2000
    ..The BCMPT successfully identifies a significant subpopulation of patients as having an inadequate penetration of mucus with otherwise normal semen characteristics...
  38. ncbi Guidelines for stroke prevention in patients with atrial fibrillation
    P A Howard
    Department of Pharmacy Practice, School of Pharmacy, University of Kansas Medical Center, Kansas City 66160 7231, USA
    Drugs 58:997-1009. 1999
    ..In particular, warfarin is underutilised in high risk elderly patients. Additional studies are needed to identify barriers that prevent implementation of the clinical trial findings into clinical practice...
  39. ncbi SP/AP area ratio in the diagnosis of Ménière's disease
    J A Ferraro
    University of Kansas Medical Center, Kansas City, USA
    Am J Audiol 8:21-8. 1999
    ..These findings indicate that measurement of the SP/AP area ratio holds promise for improving the sensitivity of ECochG in the diagnosis of MD...
  40. ncbi Predictors of brain morphology for the men of the NHLBI twin study
    C DeCarli
    Department of Neurology, University of Kansas, Kansas City, USA
    Stroke 30:529-36. 1999
    ..We extend these findings by examining the relationship between midlife cerebrovascular risk factors and later-life differences in brain atrophy, amount of abnormal white matter, and stroke on MRI...
  41. ncbi Effect of cryopreservation on cytochrome P-450 enzyme induction in cultured rat hepatocytes
    A Madan
    XenoTech, Limited Liability Company, Kansas City, Kansas 66103, USA
    Drug Metab Dispos 27:327-35. 1999
    ..In conclusion, under the conditions examined, cryopreserved rat hepatocytes appear to be a suitable in vitro system for evaluating xenobiotics as inducers of P-450 enzymes...
  42. ncbi Comparison of bactericidal activity after multidose administration of clarithromycin, azithromycin, and ceruroxime axetil against Streptococcus pneumoniae
    M K Lacy
    Department of Pharmacy Practice, School of Pharmacy, The University of Kansas Medical Center, Kansas City 66160, USA
    Int J Antimicrob Agents 10:279-83. 1998
    ..Cefuroxime axetil was active only against the PCN-susceptible isolate for 50% of the dosing interval, indicating that it should only be used for PCN-susceptible S. pneumoniae...
  43. ncbi Chronic electrical stimulation of the left ventrointermediate (Vim) thalamic nucleus for the treatment of pharmacotherapy-resistant Parkinson's disease: a differential impact on access to semantic and episodic memory?
    A I Troster
    Department of Neurology, University of Kansas Medical Center, Kansas City 66160 7314, USA
    Brain Cogn 38:125-49. 1998
    ..Parallels to findings from acute, intraoperative thalamic stimulation studies are explored. The hypothesis is offered that left Vim stimulation might facilitate access to semantic memory, but interfere with episodic memory processes...
  44. ncbi Comparison of a cathode-ray-tube and film for display of computed radiographic images
    L T Cook
    Department of Radiology, Kansas University Medical Center, Kansas City 66160 7234, USA
    Med Phys 25:1132-8. 1998
    ..These observations suggest that standard window settings should be reviewed from time to time to ensure that the display is used optimally. No special look-up table setup such as perceptual linearization was used...
  45. ncbi Tobacco and lung cancer
    B E Johnson
    Department of Medicine, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Prim Care 25:279-91. 1998
    ..Efforts should focus on the teenage population, with a combination of social, economic, and legislative interventions...
  46. ncbi Merits and shortcomings of the American Medical Association Guides to the Evaluation of Permanent Impairment, 5th edition. A physiatric perspective
    Robert D Rondinelli
    Department of Rehabilitation Medicine, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA
    Phys Med Rehabil Clin N Am 13:355-70, x. 2002
    ..Those sections of the AMA Guides most often consulted by physiatrists are examined in critical detail, including sections dealing with the spine, upper and lower extremities, neurologic impairments, and impairments due to pain...
  47. ncbi Falls in community-dwelling stroke survivors: an accumulated impairments model
    Joni Stoker Yates
    Center on Aging, University of Kansas Medical Center, Kansas City 66160, USA
    J Rehabil Res Dev 39:385-94. 2002
    ..Falling has been identified as a major complication in persons who have had a stroke. The purpose of this study was to investigate the effect of accumulated impairments on the risk of falling in community-dwelling stroke survivors...
  48. ncbi Brainstem and cortical Lewy bodies in patients presenting clinically with Alzheimer's disease
    K S SantaCruz
    Department of Pathology, University of Kansas Medical Center, Kansas City, KS 66160 7410, USA
    J Alzheimers Dis 4:11-7. 2002
    ..Thus, although the two conditions were clinically similar in this series, LBD could be distinguished from AD pathologically not only by the presence of nigral LBs but also by the relative paucity of isocortical NFTs...
  49. ncbi Preventing long-term welfare receipt: the theoretical relationship between health and poverty over the early life course
    Marcia J Nielsen
    Department of Health Policy and Management, University of Kansas Medical Center, Mail Stop 3044, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA
    Soc Sci Med 59:2285-301. 2004
    ..These findings point to the vulnerability of those who are both poor and in ill health, and should direct our policies regarding how to best prevent long term welfare receipt in future generations...
  50. ncbi Adverse effects of systemic glucocorticosteroid therapy in infants with hemangiomas
    Manju E George
    Section of Dermatology, Children s Mercy Hospital, Kansas City, MO, USA
    Arch Dermatol 140:963-9. 2004
    ..To evaluate the short- and long-term adverse effects of systemic glucocorticosteroid (GS) therapy in infants with hemangiomas...
  51. ncbi University of Kansas School of Medicine
    Daniel Swagerty
    Acad Med 79:S72-80. 2004
  52. ncbi Gender, smoking expectancies, and readiness to quit among urban African American smokers
    Kim M Pulvers
    Department of Preventive Medicine and Public Health Mailstop 1008, School of Medicine, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City 66160 7370, USA
    Addict Behav 29:1259-63. 2004
    ..Although men and women did not differ on readiness to quit, women reported higher scores on the negative affect reduction subscale than did men...
  53. ncbi Transgenic Cre expression mice for generation of erythroid-specific gene alterations
    Kenneth R Peterson
    Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas 66160 7421, USA
    Genesis 39:1-9. 2004
    ..We demonstrate that beta(S) expression was not detected in the blood of bigenics, but the gene was present in nonerythroid cells. Thus, excision of the loxP-flanked beta(S) gene was restricted to erythroid cell lineages...
  54. ncbi Compulsive behavior and eye blink in Prader-Willi syndrome: neurochemical implications
    Laura Holsen
    Department of Psychiatry and Behavioral Sciences, University of Kansas Medical Center, Kansas City 66160, USA
    Am J Ment Retard 109:197-207. 2004
    ..Our findings may provide evidence for a gene-brain-behavior link between dopamine levels and GABAergic mechanisms in individuals with Prader-Willi syndrome...
  55. ncbi Steroidal regulation of uterine edema and tissue inhibitors of metalloproteinase (TIMP)-3 messenger RNA expression is altered in TIMP-1-deficient mice
    Warren B Nothnick
    Departments of Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Biol Reprod 70:500-8. 2004
    ..These observations suggest that steroids induce uterine TIMP-1 expression and, in turn, that TIMP-1 influences TIMP-3 mRNA expression and uterine edema...
  56. ncbi Elastography imaging of small animal oncology models: a feasibility study
    Mehmet Bilgen
    Department of Radiology, University of Texas at Houston Medical School, Houston, TX, USA
    Ultrasound Med Biol 29:1291-6. 2003
    ..The results were analyzed both qualitatively and quantitatively to assess the merits of the elastographic imaging and its limitations for in vivo serial studies of tumors in small animal oncology models...
  57. ncbi Light smokers: issues and recommendations
    Kolawole S Okuyemi
    Department of Family Medicine, Kansas Cancer Institute, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Nicotine Tob Res 4:S103-12. 2002
    ....
  58. ncbi Review article: Helicobacter pylori and reflux disease
    P Sharma
    Division of Gastroenterology, University of Kansas School of Medicine, Veterans Affairs Medical Center, Kansas City, MO 64128 2295, USA
    Aliment Pharmacol Ther 17:297-305. 2003
    ..pylori eradication. It is also unclear whether H. pylori augments the antisecretory effects of proton pump inhibitors or accelerates the development of atrophic gastritis...
  59. ncbi Pathologic quiz case: clear cell tumor of the pancreas associated with hypercalcemia
    Asraa L Namiq
    Department of Pathology, University of Kansas School of Medicine, Kansas City, USA
    Arch Pathol Lab Med 127:241-2. 2003
  60. ncbi Photoactivated coumaryl-diazopyruvate fluorescent label for amine functional groups of tissues containing type-I collagen
    George T Timberlake
    Department of Ophthalmology, University of Kansas Medical Center, Kansas City, KS 66160 7379, USA
    Photochem Photobiol 76:473-9. 2002
    ..These experiments support the postulate that 1(o) or 2(o) (or both) amines in native collagenous tissues are available to serve as targets for photoactivated collagen crosslinkers for wound closure...
  61. ncbi A phase II breast cancer chemoprevention trial of oral alpha-difluoromethylornithine: breast tissue, imaging, and serum and urine biomarkers
    Carol J Fabian
    University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Clin Cancer Res 8:3105-17. 2002
    ..Subjects were randomized to 6 months of oral DFMO (0.5 g/m(2)/day) or placebo, followed by repeat fine-needle aspiration and biomarker assessment. The main study end point was an improvement in cytologic pattern...
  62. ncbi Characterization of 5-HT1A receptor-mediated [35S]GTPgammaS binding in rat hippocampal membranes
    R H Alper
    Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City 66160 7417, USA
    Eur J Pharmacol 343:303-12. 1998
    ..The reduction was not affected by WAY 100,635. We have characterized a method to assess functional activity at 5-HT1A receptors in rat hippocampal membranes by measuring agonist-induced [35S]GTPgammaS binding...

Research Grants62

  1. Brain LC-PUFAs and Maternal Mental Health
    Beth Levant; Fiscal Year: 2006
    ..These findings will also suggest novel treatments for such illnesses when they occur. ..
  2. Brain DHA, Dopamine, and Behavior: Roles in ADHD
    Beth Levant; Fiscal Year: 2006
    ..Such insights may identify a means by which certain risk factors for ADHD may be reduced or eliminated or the severity of the disease may be reduced through appropriate pre- and postnatal nutrition. ..
  3. FlaxSeed Lignan for Breast Cancer Chemoprevention
    CAROL FABIAN; Fiscal Year: 2007
    ..If positive, the results of this study will be critical to the design and implementation of a placebo-controlled Phase II prevention trial with Brevail and/or commercial flaxseed. ..
  4. CHEMOPREVENTION FOR WOMEN AT HIGH RISK OF BREAST CANCER
    CAROL FABIAN; Fiscal Year: 2003
    ..This is a collaborative effort between the University of Kansas Medical Center (KUMC), Creighton University, Ilex (current manufacturer of DFMO), University of Florida at ..
  5. Breast Cancer Prevention by Letrozole in High Risk Women
    CAROL FABIAN; Fiscal Year: 2007
    ....
  6. Breast Cancer Prevention by Letrozole in High Risk Women
    Carol J Fabian; Fiscal Year: 2010
    ....
  7. Breast Cancer Prevention by Letrozole in High Risk Women
    CAROL FABIAN; Fiscal Year: 2009
    ....
  8. Breast Cancer Risk Biomarkers and Energy Balance
    CAROL FABIAN; Fiscal Year: 2007
    ..The results of this study will potentially lead to a larger controlled trial to document the beneficial effects of exercise/diet/behavioral modification on risk factors for breast cancer development and all cause mortality. ..
  9. PATHOGENEISIS OF CYSTIC FIBROSIS IN THE GI SYSTEM
    ROBERT DE LISLE; Fiscal Year: 2003
    ..Pathology and Muclin expression will be compared in CF mice, and CF mice crossed with gastrin deficient mice (lack gastric acid secretion) to normalize intestinal Ph. ..
  10. TRANSGENIC MOUSE MODELS OF PANCREATIC EXOCRINE FUNCTION
    ROBERT DE LISLE; Fiscal Year: 2003
    ..That over expresses Muclin in the pancreatic acinar cell using the rat elastase promoter to direct cell specific expression. ..
  11. The Role of TIMP-1 in Uterine Physiology
    Warren Nothnick; Fiscal Year: 2005
    ..These studies will broaden our understanding on the role of TIMP-1 in uterine physiology and may help to develop new strategies to treat uterine disorders such as infertility, endometriosis and uterine cancer. ..
  12. Detection of Live Fibers in Injured Spinal Cord
    Mehmet Bilgen; Fiscal Year: 2007
    ..This should form a basis for future experimental investigations aimed at testing new therapies for promoting fiber connectivity, understanding SC plasticity and improving functional recovery from SCI. ..
  13. Estrogen regulation of uterine microRNAs: Novel factors in MMP-9 regulation
    Warren Nothnick; Fiscal Year: 2007
    ..Enhancing our understanding on the regulation of MMP-9 expression may lead to the establishment of novel approaches to counteract mis-expression of this protease and the diseases associated with it. ..
  14. Vascular plasticity in Injured Spinal Cord - Investigations using MRI
    Mehmet Bilgen; Fiscal Year: 2007
    ....
  15. Phase resetting using DC stimulation for seizure blockage
    Ivan Osorio; Fiscal Year: 2007
    ..3B. The significant advances made in the control of fatal arrhythmias are in part attributable to the use by cardiologists of phase resetting as an investigative and therapeutic tool. ..
  16. Telemedicine for Smoking Cessation in Rural Primary Care
    Kimber Richter; Fiscal Year: 2009
    ..QL and ITM counseling will be delivered by professional smoking cessation counselors from the University of Kansas Medical Center Campus. The counseling protocol involves an autonomy-supportive approach...
  17. Telemedicine for Smoking Cessation in Rural Primary Care
    Kimber Richter; Fiscal Year: 2009
    ..QL and ITM counseling will be delivered by professional smoking cessation counselors from the University of Kansas Medical Center Campus. The counseling protocol involves an autonomy-supportive approach...
  18. Telemedicine for Smoking Cessation in Rural Primary Care
    Kimber P Richter; Fiscal Year: 2010
    ..QL and ITM counseling will be delivered by professional smoking cessation counselors from the University of Kansas Medical Center Campus. The counseling protocol involves an autonomy-supportive approach...
  19. Describing and Measuring Tobacco Treatment in Drug Treatment
    Kimber Richter; Fiscal Year: 2007
    ..Project findings will support future policy and research to strengthen tobacco treatment services in substance abuse treatment. ..
  20. REGULATION OF BILIARY EXCRETION OF XENOBIOTICS BY MRP2
    Curtis Klaassen; Fiscal Year: 2004
    ....
  21. HEPATOBILIARY DISPOSITION IN TOXICOLOGY
    Curtis Klaassen; Fiscal Year: 2003
    ..abstract_text> ..
  22. Kansas Biomedical Research Infrastructure Network (K-BR*
    JOAN HUNT; Fiscal Year: 2003
    ..abstract_text> ..
  23. DECIDUAL CELL/PLACENTAL INTERACTIONS
    JOAN HUNT; Fiscal Year: 2002
    ..abstract_text> ..
  24. DECIDUAL CELL/PLACENTAL INTERACTIONS
    JOAN HUNT; Fiscal Year: 2007
    ..abstract_text> ..
  25. INBRE: KUMC: ADMINISTRATIVE CORE
    JOAN HUNT; Fiscal Year: 2006
    ..abstract_text> ..