Jinying Zhao

Summary

Affiliation: Tulane University
Country: USA

Publications

  1. doi request reprint A genome-wide profiling of brain DNA hydroxymethylation in Alzheimer's disease
    Jinying Zhao
    Department of Epidemiology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA Electronic address
    Alzheimers Dement . 2017
  2. pmc Promoter methylation of glucocorticoid receptor gene is associated with subclinical atherosclerosis: A monozygotic twin study
    Jinying Zhao
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA Electronic address
    Atherosclerosis 242:71-6. 2015
  3. pmc Novel metabolic markers for the risk of diabetes development in American Indians
    Jinying Zhao
    Department of Epidemiology, Tulane University School of Public Health, New Orleans, LA
    Diabetes Care 38:220-7. 2015
  4. pmc Leukotriene haplotype × diet interaction on carotid artery hypertrophy and atherosclerosis in American Indians: the Strong Heart Family Study
    Jinying Zhao
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA Electronic address
    Atherosclerosis 233:165-71. 2014
  5. pmc Association between promoter methylation of serotonin transporter gene and depressive symptoms: a monozygotic twin study
    Jinying Zhao
    School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA
    Psychosom Med 75:523-9. 2013
  6. pmc Monoamine oxidase A genotype, childhood trauma, and subclinical atherosclerosis: a twin study
    Jinying Zhao
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA
    Psychosom Med 75:471-7. 2013
  7. pmc Leukotriene A4 hydrolase haplotype, diet and atherosclerosis: a twin study
    Jinying Zhao
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, 1440 Canal Street, Suite 2010 SL18, New Orleans, LA 70112, United States
    Atherosclerosis 226:238-44. 2013
  8. pmc MAOA promoter methylation and susceptibility to carotid atherosclerosis: role of familial factors in a monozygotic twin sample
    Jinying Zhao
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA
    BMC Med Genet 13:100. 2012
  9. pmc Joint associations of 61 genetic variants in the nicotinic acetylcholine receptor genes with subclinical atherosclerosis in American Indians: a gene-family analysis
    Jingyun Yang
    Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
    Circ Cardiovasc Genet 6:89-96. 2013
  10. pmc Short leukocyte telomere length predicts risk of diabetes in american indians: the strong heart family study
    Jinying Zhao
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA
    Diabetes 63:354-62. 2014

Collaborators

Detail Information

Publications26

  1. doi request reprint A genome-wide profiling of brain DNA hydroxymethylation in Alzheimer's disease
    Jinying Zhao
    Department of Epidemiology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA Electronic address
    Alzheimers Dement . 2017
    ..The newly discovered 5-hydroxymethylcytosine mediates DNA demethylation, is highly abundant in the brain, and is dynamically regulated by life experiences. However, little is known about its genome-wide patterns and potential role in AD...
  2. pmc Promoter methylation of glucocorticoid receptor gene is associated with subclinical atherosclerosis: A monozygotic twin study
    Jinying Zhao
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA Electronic address
    Atherosclerosis 242:71-6. 2015
    ..Genetic variants in NR3C1 have been associated with atherosclerosis and related risk factors. This study investigated the association of NR3C1 promoter methylation with FMD, independent of genetic and family-level environmental factors...
  3. pmc Novel metabolic markers for the risk of diabetes development in American Indians
    Jinying Zhao
    Department of Epidemiology, Tulane University School of Public Health, New Orleans, LA
    Diabetes Care 38:220-7. 2015
    ..To identify novel metabolic markers for diabetes development in American Indians...
  4. pmc Leukotriene haplotype × diet interaction on carotid artery hypertrophy and atherosclerosis in American Indians: the Strong Heart Family Study
    Jinying Zhao
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA Electronic address
    Atherosclerosis 233:165-71. 2014
    ..This study tests nutrigenetic interaction of a previously defined leukotriene haplotype on carotid artery hypertrophy and atherosclerosis in American Indians...
  5. pmc Association between promoter methylation of serotonin transporter gene and depressive symptoms: a monozygotic twin study
    Jinying Zhao
    School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA
    Psychosom Med 75:523-9. 2013
    ..The serotonin transporter gene (SLC6A4) is a key candidate gene for depression. We examined the association between SLC6A4 promoter methylation variation and depressive symptoms using 84 monozygotic twin pairs...
  6. pmc Monoamine oxidase A genotype, childhood trauma, and subclinical atherosclerosis: a twin study
    Jinying Zhao
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA
    Psychosom Med 75:471-7. 2013
    ..The objective of this investigation was to examine whether childhood trauma moderates the association between MAOA genotype and subclinical atherosclerosis...
  7. pmc Leukotriene A4 hydrolase haplotype, diet and atherosclerosis: a twin study
    Jinying Zhao
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, 1440 Canal Street, Suite 2010 SL18, New Orleans, LA 70112, United States
    Atherosclerosis 226:238-44. 2013
    ....
  8. pmc MAOA promoter methylation and susceptibility to carotid atherosclerosis: role of familial factors in a monozygotic twin sample
    Jinying Zhao
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA
    BMC Med Genet 13:100. 2012
    ..This study investigates whether MAOA promoter methylation is associated with atherosclerosis, and whether this association is confounded by familial factors in a monozygotic (MZ) twin sample...
  9. pmc Joint associations of 61 genetic variants in the nicotinic acetylcholine receptor genes with subclinical atherosclerosis in American Indians: a gene-family analysis
    Jingyun Yang
    Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
    Circ Cardiovasc Genet 6:89-96. 2013
    ..Although a single-nucleotide polymorphism (SNP) may explain only a small portion of variability in disease, the joint effect of multiple variants in a pathway on disease susceptibility could be large...
  10. pmc Short leukocyte telomere length predicts risk of diabetes in american indians: the strong heart family study
    Jinying Zhao
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA
    Diabetes 63:354-62. 2014
    ....
  11. pmc Metabolic profiles of biological aging in American Indians: the Strong Heart Family Study
    Jinying Zhao
    Department of Epidemiology, Tulane University School of Public Health, New Orleans, LA 70112 USA
    Aging (Albany NY) 6:176-86. 2014
    ..This is the first study to interrogate the human metabolome of telomeric aging. Our results provide initial evidence for a metabolic control of LTL and may reveal previously undescribed new roles of various lipids in the aging process. ..
  12. pmc Short leukocyte telomere length predicts incidence and progression of carotid atherosclerosis in American Indians: the Strong Heart Family Study
    Shufeng Chen
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USA
    Aging (Albany NY) 6:414-27. 2014
    ..49; 95% CI, 1.09-2.03) and plaque progression (HR, 1.61; 95% CI, 1.26-2.07). Our results provide initial evidence for a potential prognostic utility of LTL in risk prediction for atherosclerosis. ..
  13. pmc Impact of biological aging on arterial aging in American Indians: findings from the Strong Heart Family Study
    Hao Peng
    Department of Epidemiology, Tulane University School of Public Health, New Orleans, LA 70112, USA
    Aging (Albany NY) 8:1583-92. 2016
    ..In summary, shorter LTL was significantly associated with an increased arterial stiffness, independent of known risk factors. This finding may shed light on the potential role of biological aging in arterial aging in American Indians. ..
  14. pmc Metabolic Profiles of Obesity in American Indians: The Strong Heart Family Study
    Qi Zhao
    Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, United States of America
    PLoS ONE 11:e0159548. 2016
    ..Future studies are warranted to replicate these findings in larger populations or other ethnic groups. ..
  15. ncbi request reprint Leukocyte telomere length and ideal cardiovascular health in American Indians: the Strong Heart Family Study
    Hao Peng
    Department of Epidemiology, College of Public Health and Health Professions, College of Medicine, University of Florida, 2004 Mowry Road, PO Box 100231, Gainesville, FL, 32610, USA
    Eur J Epidemiol . 2016
    ..Achieving four or more ideal CVH metrics was significantly associated with longer LTL. This finding suggests that achieving an ideal CVH may prevent or delay CVD, probably through promoting healthy aging...
  16. pmc Depressive symptoms are associated with leukocyte telomere length in American Indians: findings from the Strong Heart Family Study
    Qi Zhao
    Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
    Aging (Albany NY) 8:2961-2970. 2016
    ..0346). Our results suggest that depressive symptoms may accelerate biological aging through pathways beyond traditional risk factors in American Indians...
  17. pmc Short leukocyte telomere length is associated with obesity in American Indians: the Strong Heart Family study
    Shufeng Chen
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USA
    Aging (Albany NY) 6:380-9. 2014
    ..Our results may shed light on the potential role of biological aging in pathogenesis of obesity and its comorbidities...
  18. pmc Genetic variants in nicotinic acetylcholine receptor genes jointly contribute to kidney function in American Indians: the Strong Heart Family Study
    Yun Zhu
    aTulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana bRush Alzheimer s Disease Center and Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois cTexas Biomedical Research Institute, San Antonio, Texas dMedStar Health Research Institute, Hyattsville, Maryland eUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina fCenter for American Indian Health Research, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma, USA
    J Hypertens 32:1042-8; discussion 1049. 2014
    ..Whereas each single variant may only exert a small effect, the joint contribution of multiple variants to the risk of disease could be substantial...
  19. pmc Smoking-attributable mortality in American Indians: findings from the Strong Heart Study
    Mingzhi Zhang
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, 1440 Canal St Suite 2000 SL 18, New Orleans, LA, 70112, USA
    Eur J Epidemiol 30:553-61. 2015
    ..Culturally specific smoking cessation programs are urgently needed to reduce smoking-related premature deaths...
  20. pmc QTL mapping of leukocyte telomere length in American Indians: the Strong Heart Family Study
    Yun Zhu
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USA
    Aging (Albany NY) 5:704-16. 2013
    ..This is the first study to identify susceptibility loci influencing leukocyte telomere variation in American Indians, a minority group suffering from a disproportionately high rate of type 2 diabetes and other age-related disorders...
  21. pmc Genome-wide gene-gene interaction analysis for next-generation sequencing
    Jinying Zhao
    Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
    Eur J Hum Genet 24:421-8. 2016
    ..We discovered that 6 of 27 pairs of significantly interacted genes in the FHS were replicated in the independent WTCCC study and 24 pairs of significantly interacted genes after applying Bonferroni correction in the EOMI study. ..
  22. pmc Urinary triclosan concentrations are inversely associated with body mass index and waist circumference in the US general population: Experience in NHANES 2003-2010
    Shengxu Li
    Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, United States Electronic address
    Int J Hyg Environ Health 218:401-6. 2015
    ..Humans are extensively exposed to triclosan, an antibacterial and antifungal agent. Triclosan's effects on human health, however, have not been carefully investigated...
  23. pmc Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study
    Changwei Li
    From the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA C L, J H, J Z, T N K Department of Medicine, Tulane University School of Medicine, New Orleans, LA J H, J C State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China D G, J C, J H, S C Department of Epidemiology, Human Genetics and Environmental Sciences, University of Texas School of Public Health, Houston J E H Division of Biostatistics, Washington University School of Medicine, St Louis, MO D C R, C C G and Division of Prevention and Population Sciences, National Heart, Lung, Blood Institute, Bethesda, MD C E J
    Hypertension 68:348-55. 2016
    ..75×10(-10)) that were associated with at least 1 BP phenotype. In summary, we identified 8 novel and 1 previously reported BP loci through the examination of single-nucleotide polymorphism and gene-based interactions with sodium. ..
  24. pmc Gut Microbiome Associates With Lifetime Cardiovascular Disease Risk Profile Among Bogalusa Heart Study Participants
    Tanika N Kelly
    From the Department of Epidemiology, School of Public Health and Tropical Medicine T N K, L A B, H H, J Z, J H and Department of Medicine, School of Medicine L A B, J H, Tulane University, New Orleans, LA The Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX N J A, J F P and Department of Pediatrics and Medicine, University of Mississippi Medical Center, Jackson, MS A C
    Circ Res 119:956-64. 2016
    ..Few studies have systematically assessed the influence of gut microbiota on cardiovascular disease (CVD) risk...
  25. pmc Integrating mean and variance heterogeneities to identify differentially expressed genes
    Weiwei Ouyang
    Department of Global Biostatistics and Data Science, Tulane University School of Public Health and Tropical Medicine, 1440 Canal Street, Suite 2001, New Orleans, LA, 70112, USA
    BMC Bioinformatics 17:497. 2016
    ..Change in condition may alter both mean and some higher-order characteristics of the distributions of expression levels of susceptible genes...
  26. pmc Pathway analysis with next-generation sequencing data
    Jinying Zhao
    Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
    Eur J Hum Genet 23:507-15. 2015
    ..In addition, our preliminary results show that the SFPCA-based statistic has much smaller P-values to identify pathway association than other existing methods. ..