Affiliation: Tufts University
- Influences of amino acid sequences in FR1 region on binding activity of the scFv and Fab of an antibody to human gastric cancer cellsJ Li
The School of Oncology, Beijing Medical University, Beijing, PR China
Immunol Lett 71:157-65. 2000..Correction of either VL or VH N-terminal sequences can partially restore the antigen binding activity (61% for VL and 73% for VH)...
- Humanization of a mouse monoclonal antibody neutralizing TNF-alpha by guided selectionZ Wang
Central Laboratory, Navy General Hospital, Haidian District, 100037, Beijing, PR China
J Immunol Methods 241:171-84. 2000..These results suggest that guided selection is a promising strategy in murine mAb humanization...
- A novel 3p22.3 gene CMTM7 represses oncogenic EGFR signaling and inhibits cancer cell growthH Li
1 Department of Immunology, Center for Human Disease Genomics, Key Laboratory of Medical Immunology, Ministry of Health, School of Basic Medical Sciences, Peking University, Beijing, China 2 Department of Clinical Laboratory, Peking University People s Hospital, Beijing, China
Oncogene 33:3109-18. 2014..Thus, our findings suggest that CMTM7 is a novel 3p22 tumor suppressor regulating G1/S transition and EGFR/AKT signaling during tumor pathogenesis. ..
- Time-dependent diffusion tensor changes of optic nerve in patients with indirect traumatic optic neuropathyJ Li
Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, PR China
Acta Radiol 55:855-63. 2014..Diffusion tensor imaging (DTI) has been widely used as a sensitive non-invasive imaging technique to obtain information on axonal integrity...
- Prevalence of BRCA1 mutations and responses to neoadjuvant chemotherapy among BRCA1 carriers and non-carriers with triple-negative breast cancerC Wang
Breast Center, Key Laboratory of Carcinogenesis and Translational Research Ministry of Education, Peking University Cancer Hospital and Institute, Beijing, PR China
Ann Oncol 26:523-8. 2015....
- Total blood volume of Asian patients undergoing cardiac surgery is far from that predicted by conventional methodsZ S Jia
Department of Extracorporeal Circulation, Beijing An Zhen Hospital, Capital Medical University, An Ding Men Wai An Zhen Li, Chao Yang District, Beijing, PR China
J Cardiovasc Surg (Torino) 54:423-30. 2013..We aimed to evaluate differences between calculation of TBV by Nadler's formula, a classic reference book method, and an established formula calculated by the authors...
- Association study of functional polymorphisms in serotonin transporter gene with temporal lobe epilepsy in Han Chinese populationJ Li
National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China
Eur J Neurol 19:351-3. 2012..We investigated the association between three common polymorphisms of 5-HTT gene, which may influence gene expression or function, and risk for TLE...