Lara S Hwa

Summary

Affiliation: Tufts University
Country: USA

Publications

  1. pmc Alcohol in excess: CRF₁ receptors in the rat and mouse VTA and DRN
    Lara S Hwa
    Department of Psychology, Tufts University, 530 Boston Avenue, Medford, MA 02155, USA
    Psychopharmacology (Berl) 225:313-27. 2013
  2. pmc Persistent escalation of alcohol drinking in C57BL/6J mice with intermittent access to 20% ethanol
    Lara S Hwa
    Psychology Department, Tufts University, Medford, Massachusetts 02155, USA
    Alcohol Clin Exp Res 35:1938-47. 2011
  3. pmc Dissociation of μ-opioid receptor and CRF-R1 antagonist effects on escalated ethanol consumption and mPFC serotonin in C57BL/6J mice
    Lara S Hwa
    Department of Psychology, Tufts University, Medford, MA, USA
    Addict Biol 21:111-24. 2016
  4. pmc α2-containing GABA(A) receptors: a requirement for midazolam-escalated aggression and social approach in mice
    Emily L Newman
    Department of Psychology, Tufts University, Medford, MA, 02144, USA
    Psychopharmacology (Berl) 232:4359-69. 2015
  5. pmc Aggression and increased glutamate in the mPFC during withdrawal from intermittent alcohol in outbred mice
    Lara S Hwa
    Department of Psychology, Tufts University, 530 Boston Avenue, Medford, MA, 02155, USA
    Psychopharmacology (Berl) 232:2889-902. 2015
  6. pmc Corticotropin Releasing Factor Binding Protein and CRF2 Receptors in the Ventral Tegmental Area: Modulation of Ethanol Binge Drinking in C57BL/6J Mice
    Lucas Albrechet-Souza
    Department of Psychology, Tufts University, Medford, Massachusetts
    Alcohol Clin Exp Res 39:1609-18. 2015
  7. pmc Social stress-escalated intermittent alcohol drinking: modulation by CRF-R1 in the ventral tegmental area and accumbal dopamine in mice
    Lara S Hwa
    Psychology Department, Tufts University, 530 Boston Avenue, Medford, MA, 02155, USA
    Psychopharmacology (Berl) 233:681-90. 2016
  8. pmc Social stress and escalated drug self-administration in mice I. Alcohol and corticosterone
    Kevin J Norman
    Department of Psychology, Tufts University, Medford, MA, USA
    Psychopharmacology (Berl) 232:991-1001. 2015
  9. pmc Prevention of alcohol-heightened aggression by CRF-R1 antagonists in mice: critical role for DRN-PFC serotonin pathway
    Isabel M Quadros
    Department of Psychology, Tufts University, Medford, MA, USA
    Neuropsychopharmacology 39:2874-83. 2014

Collaborators

  • Klaus A Miczek
  • Joseph F DeBold
  • Lucas Albrechet-Souza
  • Xiao Han
  • Kevin J Norman
  • Emily L Newman
  • Isabel M Quadros
  • Uwe Rudolph
  • Jacob A Klickstein
  • Jacob A Seiden
  • Aki Takahashi
  • Adam Chu
  • Yang Chen
  • Eric Y Zhang
  • Kiersten S Smith
  • Akiko Shimamoto
  • Julia Carlson

Detail Information

Publications9

  1. pmc Alcohol in excess: CRF₁ receptors in the rat and mouse VTA and DRN
    Lara S Hwa
    Department of Psychology, Tufts University, 530 Boston Avenue, Medford, MA 02155, USA
    Psychopharmacology (Berl) 225:313-27. 2013
    ..Escalated consumption is largely controlled by neurocircuitry that is important for reward and affect, such as the ventral tegmental area (VTA) and the dorsal raphé nucleus (DRN)...
  2. pmc Persistent escalation of alcohol drinking in C57BL/6J mice with intermittent access to 20% ethanol
    Lara S Hwa
    Psychology Department, Tufts University, Medford, Massachusetts 02155, USA
    Alcohol Clin Exp Res 35:1938-47. 2011
    ..Intermittent 24-hour cycles of ethanol access and deprivation can generate high levels of voluntary ethanol drinking in rats...
  3. pmc Dissociation of μ-opioid receptor and CRF-R1 antagonist effects on escalated ethanol consumption and mPFC serotonin in C57BL/6J mice
    Lara S Hwa
    Department of Psychology, Tufts University, Medford, MA, USA
    Addict Biol 21:111-24. 2016
    ..This suggests the mPFC may not be an essential location to intermittent drinking, as evidenced by different effects on serotonin signaling to the forebrain yet similar behavioral findings. ..
  4. pmc α2-containing GABA(A) receptors: a requirement for midazolam-escalated aggression and social approach in mice
    Emily L Newman
    Department of Psychology, Tufts University, Medford, MA, 02144, USA
    Psychopharmacology (Berl) 232:4359-69. 2015
    ..Under specific conditions, BZDs escalate aggression in some individuals. Specific effects of BZDs have been linked to the α-subunit subtype composition of GABAA receptors...
  5. pmc Aggression and increased glutamate in the mPFC during withdrawal from intermittent alcohol in outbred mice
    Lara S Hwa
    Department of Psychology, Tufts University, 530 Boston Avenue, Medford, MA, 02155, USA
    Psychopharmacology (Berl) 232:2889-902. 2015
    ..Heavy EtOH use and exaggerated responses during withdrawal may be treated using glutamatergic N-methyl-D-aspartate receptor (NMDAR) antagonists...
  6. pmc Corticotropin Releasing Factor Binding Protein and CRF2 Receptors in the Ventral Tegmental Area: Modulation of Ethanol Binge Drinking in C57BL/6J Mice
    Lucas Albrechet-Souza
    Department of Psychology, Tufts University, Medford, Massachusetts
    Alcohol Clin Exp Res 39:1609-18. 2015
    ..In humans, several nucleotide polymorphisms in the CRFBP gene have been associated with EtOH abuse...
  7. pmc Social stress-escalated intermittent alcohol drinking: modulation by CRF-R1 in the ventral tegmental area and accumbal dopamine in mice
    Lara S Hwa
    Psychology Department, Tufts University, 530 Boston Avenue, Medford, MA, 02155, USA
    Psychopharmacology (Berl) 233:681-90. 2016
    ..Excessive alcohol (EtOH) drinking is difficult to model in animals despite the extensive human literature demonstrating that stress increases EtOH consumption...
  8. pmc Social stress and escalated drug self-administration in mice I. Alcohol and corticosterone
    Kevin J Norman
    Department of Psychology, Tufts University, Medford, MA, USA
    Psychopharmacology (Berl) 232:991-1001. 2015
    ..Stress experiences have been shown to be a risk factor for alcohol abuse in humans; however, a reliable mouse model using episodic social stress has yet to be developed...
  9. pmc Prevention of alcohol-heightened aggression by CRF-R1 antagonists in mice: critical role for DRN-PFC serotonin pathway
    Isabel M Quadros
    Department of Psychology, Tufts University, Medford, MA, USA
    Neuropsychopharmacology 39:2874-83. 2014
    ..Neither alcohol nor CP-154,526 alone affected 5-HT release in the mPFC. The present results suggest the DRN as a critical site for CRF-R1 to modulate alcohol-heightened aggression via action on the serotonergic DRN-PFC pathway. ..