Timothy E McAlindon

Summary

Affiliation: Tufts-New England Medical Center
Country: USA

Publications

  1. ncbi request reprint Nutraceuticals: do they work and when should we use them?
    Timothy E McAlindon
    Tufts New England Medical Center, Boston, MA 02111, USA
    Best Pract Res Clin Rheumatol 20:99-115. 2006
  2. ncbi request reprint Changes in barometric pressure and ambient temperature influence osteoarthritis pain
    Tim McAlindon
    Division of Rheumatology, Tufts New England Medical Center, Boston, Mass 02111, USA
    Am J Med 120:429-34. 2007
  3. pmc Feasibility and validity were demonstrated of an online case-control study using the prototype of recent-onset systemic lupus erythematosus
    Timothy McAlindon
    Division of Rheumatology, Tufts New England Medical Center, 750 Washington Street, Box 406, Boston, MA 02111, USA
    J Clin Epidemiol 61:671-8. 2008
  4. pmc Conducting clinical trials over the internet: feasibility study
    Tim McAlindon
    Division of Rheumatology, Tufts New England Medical Center, Box 406, 715 Washington Street, Boston, MA 02111, USA
    BMJ 327:484-7. 2003
  5. ncbi request reprint Assessment of strategies for identifying diagnosed cases of systemic lupus erythematosus through self-report
    T E McAlindon
    Division of Rheumatology, Tufts New England Medical Center, Boston, MA 02111, USA
    Lupus 12:754-9. 2003
  6. ncbi request reprint Why are clinical trials of glucosamine no longer uniformly positive?
    Tim McAlindon
    Division of Rheumatology, Tufts New England Medical Center, Box 406, 750 Washington Street, Boston, MA 02111, USA
    Rheum Dis Clin North Am 29:789-801. 2003
  7. ncbi request reprint Effectiveness of glucosamine for symptoms of knee osteoarthritis: results from an internet-based randomized double-blind controlled trial
    Timothy McAlindon
    Division of Rheumatology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Am J Med 117:643-9. 2004
  8. ncbi request reprint Nutritional factors and osteoarthritis: recent developments
    Timothy E McAlindon
    Tufts New England Medical Center, Boston, MA 02111, USA
    Curr Opin Rheumatol 17:647-52. 2005
  9. pmc Coronal tibial slope is associated with accelerated knee osteoarthritis: data from the Osteoarthritis Initiative
    Jeffrey B Driban
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box 406, Boston, MA, 02111, USA
    BMC Musculoskelet Disord 17:299. 2016
  10. pmc Development of a rapid knee cartilage damage quantification method using magnetic resonance images
    Ming Zhang
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box 406, Boston, MA 02111, USA
    BMC Musculoskelet Disord 15:264. 2014

Research Grants

Collaborators

Detail Information

Publications34

  1. ncbi request reprint Nutraceuticals: do they work and when should we use them?
    Timothy E McAlindon
    Tufts New England Medical Center, Boston, MA 02111, USA
    Best Pract Res Clin Rheumatol 20:99-115. 2006
    ....
  2. ncbi request reprint Changes in barometric pressure and ambient temperature influence osteoarthritis pain
    Tim McAlindon
    Division of Rheumatology, Tufts New England Medical Center, Boston, Mass 02111, USA
    Am J Med 120:429-34. 2007
    ..Individuals with osteoarthritis often assert that change in the weather influences their pain, but the evidence is inconclusive. Our objective was to determine if short-term weather parameters influence knee osteoarthritis pain...
  3. pmc Feasibility and validity were demonstrated of an online case-control study using the prototype of recent-onset systemic lupus erythematosus
    Timothy McAlindon
    Division of Rheumatology, Tufts New England Medical Center, 750 Washington Street, Box 406, Boston, MA 02111, USA
    J Clin Epidemiol 61:671-8. 2008
    ..To test the feasibility and validity of the online case-control study design through the empirical deployment of a prototype study of recent-onset systemic lupus erythematosus (SLE)...
  4. pmc Conducting clinical trials over the internet: feasibility study
    Tim McAlindon
    Division of Rheumatology, Tufts New England Medical Center, Box 406, 715 Washington Street, Boston, MA 02111, USA
    BMJ 327:484-7. 2003
  5. ncbi request reprint Assessment of strategies for identifying diagnosed cases of systemic lupus erythematosus through self-report
    T E McAlindon
    Division of Rheumatology, Tufts New England Medical Center, Boston, MA 02111, USA
    Lupus 12:754-9. 2003
    ..SLE case confirmation strategies can be complemented by the use of criteria checklists sent directly to participants' physicians...
  6. ncbi request reprint Why are clinical trials of glucosamine no longer uniformly positive?
    Tim McAlindon
    Division of Rheumatology, Tufts New England Medical Center, Box 406, 750 Washington Street, Boston, MA 02111, USA
    Rheum Dis Clin North Am 29:789-801. 2003
    ..These issues include design issues and important differences in sample characteristics. Ultimately, it is clear that more work needs to be done to clarify issues surrounding the efficacy and utility of the various glucosamine compounds...
  7. ncbi request reprint Effectiveness of glucosamine for symptoms of knee osteoarthritis: results from an internet-based randomized double-blind controlled trial
    Timothy McAlindon
    Division of Rheumatology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Am J Med 117:643-9. 2004
    ..To present the safety and effectiveness results of a prototypical 12-week, double-blind, randomized placebo-controlled trial of glucosamine among subjects with knee osteoarthritis who were recruited and followed entirely over the Internet...
  8. ncbi request reprint Nutritional factors and osteoarthritis: recent developments
    Timothy E McAlindon
    Tufts New England Medical Center, Boston, MA 02111, USA
    Curr Opin Rheumatol 17:647-52. 2005
    ..This review focuses on how the evidence for a role of nutritional factors or nutritional supplements in the management of knee osteoarthritis has been changed by recent research...
  9. pmc Coronal tibial slope is associated with accelerated knee osteoarthritis: data from the Osteoarthritis Initiative
    Jeffrey B Driban
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box 406, Boston, MA, 02111, USA
    BMC Musculoskelet Disord 17:299. 2016
    ..We aimed to determine if baseline coronal tibial slope is associated with incident accelerated knee osteoarthritis or common knee osteoarthritis...
  10. pmc Development of a rapid knee cartilage damage quantification method using magnetic resonance images
    Ming Zhang
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box 406, Boston, MA 02111, USA
    BMC Musculoskelet Disord 15:264. 2014
    ..In this study we tested the feasibility, reliability, and construct validity of a novel osteoarthritis cartilage damage quantification method (Cartilage Damage Index [CDI]) that utilizes informative locations on knee MRIs...
  11. pmc Best performing definition of accelerated knee osteoarthritis: data from the Osteoarthritis Initiative
    Jeffrey B Driban
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box 406, Boston, MA 02111, USA
    Ther Adv Musculoskelet Dis 8:165-171. 2016
    ..We evaluated agreement among several definitions of accelerated knee osteoarthritis (AKOA) and construct validity by comparing their individual associations with injury, age, obesity, and knee pain...
  12. pmc Meniscal extrusion or subchondral damage characterize incident accelerated osteoarthritis: Data from the Osteoarthritis Initiative
    Jeffrey B Driban
    Division of Rheumatology, Tufts Medical Center, Boston, Massachusetts
    Clin Anat 28:792-9. 2015
    ..Recognizing meniscal extrusion and/or change in shape, lateral meniscal tear, or acute subchondral damage may be vital for identifying individuals at risk for accelerated KOA...
  13. pmc Overweight older adults, particularly after an injury, are at high risk for accelerated knee osteoarthritis: data from the Osteoarthritis Initiative
    Jeffrey B Driban
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box 406, Boston, MA, 02111, USA
    Clin Rheumatol 35:1071-6. 2016
    ..While older age and greater BMI are independently associated with AKOA, we found that older individuals who had a higher BMI, particularly if they have an injury, were more likely to develop AKOA than common KOA. ..
  14. pmc Individuals with incident accelerated knee osteoarthritis have greater pain than those with common knee osteoarthritis progression: data from the Osteoarthritis Initiative
    Jeffrey B Driban
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box 406, Boston, MA, 02111, USA
    Clin Rheumatol 35:1565-71. 2016
    ..In conclusion, AKOA may be a painful and disabling phenotype that warrants more attention by clinicians and researchers. ..
  15. pmc Development of a Rapid Cartilage Damage Quantification Method for the Lateral Tibiofemoral Compartment Using Magnetic Resonance Images: Data from the Osteoarthritis Initiative
    Ming Zhang
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, P O Box 406, Boston, MA 02111, USA
    Biomed Res Int 2015:634275. 2015
    ..It may be an efficient method to measure lateral tibiofemoral articular cartilage in large clinical and epidemiologic studies. ..
  16. pmc Quantification of bone marrow lesion volume and volume change using semi-automated segmentation: data from the osteoarthritis initiative
    Jincheng Pang
    Department of Electrical and Computer Engineering, Tufts University, 216 Halligan Hall, Medford, MA 02155, USA
    BMC Musculoskelet Disord 14:3. 2013
    ..To determine the validity of a semi-automated segmentation of bone marrow lesions (BMLs) in the knee...
  17. pmc Dietary Fat and Progression of Knee Osteoarthritis Dietary Fat Intake and Radiographic Progression of Knee Osteoarthritis: Data from the Osteoarthritis Initiative
    Bing Lu
    Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, United States
    Arthritis Care Res (Hoboken) . 2016
    ..Few studies have investigated the role of dietary factors on knee osteoarthritis (OA) progression. We examined the prospective association of dietary fat intake with radiographic progression of knee OA...
  18. pmc Defining and evaluating a novel outcome measure representing end-stage knee osteoarthritis: data from the Osteoarthritis Initiative
    Jeffrey B Driban
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box 406, Boston, MA, 02111, USA
    Clin Rheumatol 35:2523-30. 2016
    ..Older age and quadriceps weakness predicted esKOA. esKOA is also characterized by poor health-related outcomes. This definition of esKOA could be a new clinically relevant outcome measure for osteoarthritis research. ..
  19. pmc Magnetic Resonance Image Sequence Influences the Relationship between Bone Marrow Lesions Volume and Pain: Data from the Osteoarthritis Initiative
    Ming Zhang
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box No 406, Boston, MA 02111, USA
    Biomed Res Int 2015:731903. 2015
    ..The change in WOMAC pain is correlated with BML volume change on IW FS (r s = 0.37) but not DESS. Overall, BML quantification on IW FS offers better validity and statistical power than BML quantification on a 3D DESS sequence. ..
  20. pmc Knee Pain and a Prior Injury Are Associated with Increased Risk of a New Knee Injury: Data from the Osteoarthritis Initiative
    Jeffrey B Driban
    From the Division of Rheumatology, and The Institute for Clinical Research and Health Policy Studies, Tufts Medical Center Tufts Clinical and Translational Science Institute, Tufts University Brigham and Women s Hospital Harvard Medical School, Boston, Massachusetts Medical Care Line and Research Care Line, Houston Health Services Research and Development HSR and D Center of Excellence, Michael E DeBakey Veterans Affairs Medical Center Section of Immunology, Allergy, and Rheumatology, Baylor College of Medicine, Houston, Texas Center for Primary Care and Prevention, Alpert Medical School of Brown University, Providence, Rhode Island, USA J B Driban, PhD, ATC, CSCS, Assistant Professor, Division of Rheumatology, Tufts Medical Center G H Lo, MD, MSc, Assistant Professor, Medical Care Line and Research Care Line, HSR and D Center of Excellence, Michael E DeBakey VA Medical Center, and Section of Immunology, Allergy, and Rheumatology, Baylor College of Medicine C B Eaton, MD, MS, Director of Primary Care and Prevention, Center for Primary Care and Prevention, Alpert Medical School of Brown University L L Price, MAS
    J Rheumatol 42:1463-9. 2015
    ..We explored whether knee pain or a history of knee injury were associated with a knee injury in the following 12 months...
  21. pmc Relationship of bone mineral density to progression of knee osteoarthritis
    Ji Y Lee
    Tufts Medical Center, Boston, MA 02111, USA
    Arthritis Rheum 65:1541-6. 2013
    ..To evaluate the longitudinal relationship between bone mineral density (BMD) and BMD changes and the progression of knee osteoarthritis (OA), as measured by cartilage outcomes...
  22. ncbi request reprint Glucosamine for pain in osteoarthritis: why do trial results differ?
    Steven C Vlad
    Boston University Medical Center, Boston, Massachusetts 02118, USA
    Arthritis Rheum 56:2267-77. 2007
    ..Investigators in trials of glucosamine report a range of estimates for efficacy, making conclusions difficult. We undertook this study to identify factors that explain heterogeneity in trials of glucosamine...
  23. ncbi request reprint Association of periodontal disease and tooth loss with rheumatoid arthritis in the US population
    Paola de Pablo
    Division of Rheumatology, Department of Medicine, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    J Rheumatol 35:70-6. 2008
    ..To test for an association of periodontitis and tooth loss with rheumatoid arthritis (RA)...
  24. pmc Is lipstick associated with the development of systemic lupus erythematosus (SLE)?
    Jun Wang
    Division of Rheumatology, Tufts Medical Center, Boston, MA 02111, USA
    Clin Rheumatol 27:1183-7. 2008
    ..Epidemiologic studies of SLE should include this exposure in exploring its environmental triggers...
  25. doi request reprint Therapeutic trajectory of hyaluronic acid versus corticosteroids in the treatment of knee osteoarthritis: a systematic review and meta-analysis
    Raveendhara R Bannuru
    Tufts University School of Medicine, Boston, MA, USA
    Arthritis Rheum 61:1704-11. 2009
    ..To compare the efficacy of intraarticular hyaluronic acid with corticosteroids for knee osteoarthritis (OA)...
  26. pmc Safety of Repeated Injections of Sodium Hyaluronate (SUPARTZ) for Knee Osteoarthritis: A Systematic Review and Meta-Analysis
    Raveendhara R Bannuru
    Center for Treatment Comparison and Integrative Analysis, Division of Rheumatology, Tufts Medical Center, Boston, MA, USA
    Cartilage 7:322-32. 2016
    ..However, the safety of repeated injection series is reported to vary between commercial products. This report describes a systematic review of safety data on repeated treatment courses of SUPARTZ...
  27. pmc Validation of quantitative magnetic resonance imaging-based apparent bone volume fraction in peri-articular tibial bone of cadaveric knees
    Jeffrey B Driban
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box 406, Boston, MA 02111, USA
    BMC Musculoskelet Disord 15:143. 2014
    ..g., micro-computed tomography [microCT]). In this cadaveric validation study we explored the association between MR-based apparent BV/TV and microCT-based BV/TV in the proximal peri-articular medial tibia...
  28. pmc Quantitative bone marrow lesion size in osteoarthritic knees correlates with cartilage damage and predicts longitudinal cartilage loss
    Jeffrey B Driban
    Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box 406, Boston, MA 02111, USA
    BMC Musculoskelet Disord 12:217. 2011
    ....
  29. pmc Validity of self-reported rheumatoid arthritis in a large cohort: results from the Black Women's Health Study
    Margaret K Formica
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215, USA
    Arthritis Care Res (Hoboken) 62:235-41. 2010
    ....
  30. doi request reprint Relative efficacy of hyaluronic acid in comparison with NSAIDs for knee osteoarthritis: a systematic review and meta-analysis
    Raveendhara R Bannuru
    Center for Treatment Comparison and Integrative Analysis CTCIA, Tufts Medical Center, 800 Washington St 63, Boston, MA 02111 Division of Rheumatology, Tufts Medical Center, Boston, MA Electronic address
    Semin Arthritis Rheum 43:593-9. 2014
    ..To assess the relative efficacy of intra-articular hyaluronic acid (IAHA) in comparison with non-steroidal anti-inflammatory drugs (NSAIDs) for knee osteoarthritis (OA)...
  31. ncbi request reprint Considerations in the treatment of early osteoarthritis
    Senada Arabelovic
    Tufts New England Medical Center, Division of Rheumatology, 750 Washington Street, NEMC Box 406, Boston, MA 02111, USA
    Curr Rheumatol Rep 7:29-35. 2005
    ....
  32. pmc Changes in serum levels of glucosamine and sulphate after ingestion of glucosamine sulphate with and without simultaneous ingestion of glucose
    Beth A Biggee
    Ann Rheum Dis 66:1403-4. 2007
  33. ncbi request reprint Effect of glutathione S-transferase polymorphisms and proximity to hazardous waste sites on time to systemic lupus erythematosus diagnosis: results from the Roxbury lupus project
    Elizabeth W Karlson
    Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Arthritis Rheum 56:244-54. 2007
    ..Our goal was to assess association of residential proximity to hazardous waste sites and genetic variation in 3 glutathione Stransferase (GST) genes (GSTM1, GSTT1, and GSTP1) with age at diagnosis of SLE...
  34. ncbi request reprint Smoking, alcohol consumption, and risk of systemic lupus erythematosus in the Black Women's Health Study
    Margaret K Formica
    Clinical Epidemiology Research and Training Unit and the Slone Epidemiology Center, Boston University School of Medicine, Massachusetts 02118, USA
    J Rheumatol 30:1222-6. 2003
    ..We prospectively investigated the associations of smoking and alcohol consumption with incident SLE in the Black Women's Health Study (BWHS)...

Research Grants1

  1. RESEARCH TRAINING IN RHEUMATOLOGY AT NEW ENGLAND MEDICAL
    Timothy McAlindon; Fiscal Year: 2005
    ..The participation of faculty members and trainees from Adult and Pediatric Rheumatology and Basic Science Departments offers a training opportunity in infection and immunity related to rheumatic diseases. ..