Tufts-New England Medical Center

Summary

Organization: Tufts-New England Medical Center
Country: USA

Top Publications

  1. doi Sensorineural hearing loss in patients with inflammatory bowel disease
    Collin S Karmody
    Department of Otolaryngology, Head and Neck Surgery, Tufts Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Am J Otolaryngol 30:166-70. 2009
  2. ncbi Can multivariable risk-benefit profiling be used to select treatment-favorable patients for thrombolysis in stroke in the 3- to 6-hour time window?
    David M Kent
    Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Stroke 37:2963-9. 2006
  3. ncbi A Delphi approach to reach consensus on primary care guidelines regarding youth violence prevention
    Edward De Vos
    Pediatric and Adolescent Health Research Center, Floating Hospital for Children at Tufts New England Medical Center, Boston, MA, USA
    Pediatrics 118:e1109-15. 2006
  4. ncbi Optimizing staging for hepatocellular carcinoma before liver transplantation: A retrospective analysis of the UNOS/OPTN database
    Richard B Freeman
    Division of Transplantation, Department of Surgery, Tufts New England Medical Center, Boston, MA 02111, USA
    Liver Transpl 12:1504-11. 2006
  5. ncbi Job performance deficits due to depression
    David A Adler
    The Health Institute, Tufts New England Medical Center, 750 Washington St, No 345, Boston, MA 02111, USA
    Am J Psychiatry 163:1569-76. 2006
  6. ncbi Therapeutic targets in melanoma: map kinase pathway
    Frank G Haluska
    Cancer Center and Division of Hematology Oncology, Tufts New England Medical Center, Boston, MA 02111, USA
    Curr Oncol Rep 8:400-5. 2006
  7. ncbi The case for cytomegalovirus prophylaxis in solid organ transplantation
    David R Snydman
    Division of Geographic Medicine and Infectious Diseases, Department of Medicine, Tufts New England Medical Center and Tufts University School of Medicine, Boston, MA, USA
    Rev Med Virol 16:289-95. 2006
  8. ncbi Assessing kidney function--measured and estimated glomerular filtration rate
    Lesley A Stevens
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    N Engl J Med 354:2473-83. 2006
  9. pmc Aging and HIV infection
    Rakhi Kohli
    Division of Geographic Medicine and Infectious Disease, Department of Medicine, Tufts New England Medical Center, 750 Washington Street 41, Boston, MA 02111, USA
    J Urban Health 83:31-42. 2006
  10. ncbi Acute hepatitis C virus infection in incarcerated injection drug users
    Barbara H McGovern
    Lemuel Shattuck Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Clin Infect Dis 42:1663-70. 2006

Research Grants

  1. Liver Transplantation for Hepatocellular Carcinoma
    Richard Freeman; Fiscal Year: 2005
  2. Assisted Patient-Selection for Thrombolytics in Stroke
    David Kent; Fiscal Year: 2007
  3. Extending Safe and Effective Thrombolysis for Stroke
    David Kent; Fiscal Year: 2005
  4. Kidney Disease, Stroke and Cognitive Impairment
    Daniel Weiner; Fiscal Year: 2007
  5. Glycemic Index and Metabolic Syndrome
    ANASTASSIOS PITTAS; Fiscal Year: 2005
  6. Vitamin D Status and Incident Type 2 Diabetes
    ANASTASSIOS PITTAS; Fiscal Year: 2007
  7. The Role of Bone in Osteoarthritis Progression
    Timothy McAlindon; Fiscal Year: 2007
  8. RESEARCH TRAINING IN RHEUMATOLOGY AT NEW ENGLAND MEDICAL
    Timothy McAlindon; Fiscal Year: 2005
  9. Clinical Research Training in Infectious Diseases
    David Snydman; Fiscal Year: 2007
  10. Physician & Scientist Training in Developmental Genetics
    DIANA BIANCHI; Fiscal Year: 2007

Detail Information

Publications62

  1. doi Sensorineural hearing loss in patients with inflammatory bowel disease
    Collin S Karmody
    Department of Otolaryngology, Head and Neck Surgery, Tufts Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Am J Otolaryngol 30:166-70. 2009
    ..The study aimed to discuss the association between sensorineural hearing loss (SNHL) and inflammatory bowel disease (IBD)...
  2. ncbi Can multivariable risk-benefit profiling be used to select treatment-favorable patients for thrombolysis in stroke in the 3- to 6-hour time window?
    David M Kent
    Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Stroke 37:2963-9. 2006
    ..We sought to examine whether such a multivariate predictive instrument might be useful in selecting patients with a favorable risk-benefit treatment profile for therapy after 3 hours...
  3. ncbi A Delphi approach to reach consensus on primary care guidelines regarding youth violence prevention
    Edward De Vos
    Pediatric and Adolescent Health Research Center, Floating Hospital for Children at Tufts New England Medical Center, Boston, MA, USA
    Pediatrics 118:e1109-15. 2006
    ..The purpose of this study was to systematically identify and prioritize specific counseling topics in violence prevention that could be integrated into anticipatory guidance best practice...
  4. ncbi Optimizing staging for hepatocellular carcinoma before liver transplantation: A retrospective analysis of the UNOS/OPTN database
    Richard B Freeman
    Division of Transplantation, Department of Surgery, Tufts New England Medical Center, Boston, MA 02111, USA
    Liver Transpl 12:1504-11. 2006
    ..In conclusion, current imaging requirements for RS prior to liver transplantation are unacceptably inaccurate. Future policy should require more accurate modalities or combinations of techniques...
  5. ncbi Job performance deficits due to depression
    David A Adler
    The Health Institute, Tufts New England Medical Center, 750 Washington St, No 345, Boston, MA 02111, USA
    Am J Psychiatry 163:1569-76. 2006
    ..This study assessed the relationship between depression severity and job performance among employed primary care patients...
  6. ncbi Therapeutic targets in melanoma: map kinase pathway
    Frank G Haluska
    Cancer Center and Division of Hematology Oncology, Tufts New England Medical Center, Boston, MA 02111, USA
    Curr Oncol Rep 8:400-5. 2006
    ..Agents that specifically target BRAF, such as sorafenib, as well as new molecules that function both upstream and downstream of BRAF, are being actively investigated...
  7. ncbi The case for cytomegalovirus prophylaxis in solid organ transplantation
    David R Snydman
    Division of Geographic Medicine and Infectious Diseases, Department of Medicine, Tufts New England Medical Center and Tufts University School of Medicine, Boston, MA, USA
    Rev Med Virol 16:289-95. 2006
    ..Future trials with longer periods of prophylaxis are being undertaken...
  8. ncbi Assessing kidney function--measured and estimated glomerular filtration rate
    Lesley A Stevens
    Division of Nephrology, Tufts New England Medical Center, Boston, MA 02111, USA
    N Engl J Med 354:2473-83. 2006
  9. pmc Aging and HIV infection
    Rakhi Kohli
    Division of Geographic Medicine and Infectious Disease, Department of Medicine, Tufts New England Medical Center, 750 Washington Street 41, Boston, MA 02111, USA
    J Urban Health 83:31-42. 2006
    ..In this paper, we discuss the health issues confronting HIV-infected older adults and areas for future research...
  10. ncbi Acute hepatitis C virus infection in incarcerated injection drug users
    Barbara H McGovern
    Lemuel Shattuck Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Clin Infect Dis 42:1663-70. 2006
    ....
  11. ncbi Insulin therapy and in-hospital mortality in critically ill patients: systematic review and meta-analysis of randomized controlled trials
    Anastassios G Pittas
    Division of Endocrinology, Diabetes and Metabolism and Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, 750 Washington Street 268, Boston, MA 02111, USA
    JPEN J Parenter Enteral Nutr 30:164-72. 2006
    ..Hyperglycemia is common in critically ill hospitalized patients and has been associated with adverse outcomes, including increased mortality. In this review, we examine the effect of insulin therapy on mortality in critically ill patients...
  12. ncbi High-density lipoprotein cholesterol-raising strategies
    Jeffrey T Kuvin
    Division of Cardiology, Department of Medicine, Tufts New England Medical Center, Tufts University School of Medicine Boston, Massachusettes 0211, USA
    J Cardiovasc Pharmacol 47:196-204. 2006
    ..Recent findings regarding the role of HDL-C in cholesterol metabolism offer new strategies designed to target atherosclerosis. This review highlights the utility of existing HDL-C-raising strategies and examines new potential therapies...
  13. ncbi Vitreopapillary traction confirmed by optical coherence tomography
    Thomas R Hedges
    New England Eye Center, Boston, MA 02116, USA
    Arch Ophthalmol 124:279-81. 2006
  14. ncbi Evaluation of in vitro interaction of daptomycin with gentamicin or beta-lactam antibiotics against Staphylococcus aureus and Enterococci by FIC index and timed-kill curves
    D R Snydman
    Tufts New England Medical Center, 750 Washington St, Boston, MA 02111, USA
    J Chemother 17:614-21. 2005
    ..A bactericidal effect was exerted in 5/7 synergistic combinations. The in vitro data suggest that daptomycin combined with other antibiotics may be microbiologically beneficial and not antagonistic...
  15. ncbi Hoxb-5 down regulation alters Tenascin-C, FGF10 and Hoxb gene expression patterns in pseudoglandular period fetal mouse lung
    MaryAnn V Volpe
    Department of Pediatrics, Division of Newborn Medicine, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Front Biosci 12:860-73. 2007
    ..ECM changes induced by Hoxb-5 may affect mesenchymal-epithelial cell signaling to alter spatial and cellular restriction of FGF10. Hoxb-5 may also affect lung airway branching indirectly by cross regulation of other Hoxb genes...
  16. ncbi Hypercalcemia in a newly arrived international adoptee
    Wilma Chan
    International Adoption Clinic, Tufts New England Medical Center, Boston, MA 02111, USA
    J Pediatr Endocrinol Metab 19:1249-50. 2006
  17. ncbi The integration of signaling by multiprotein complexes containing Raf kinases
    John M Kyriakis
    The Molecular Cardiology Research Institute, Tufts New England Medical Center and the Department of Medicine, Tufts University School of Medicine, 750 Washington Street, Boston, MA 02111, USA
    Biochim Biophys Acta 1773:1238-47. 2007
    ..This review will focus on two signal integrating multiprotein complexes that involve Raf family kinases: the MLK3-B-Raf-Raf-1 complex and the Raf-1-Mst-2 complex...
  18. doi Parathyroid surgery: what the radiologists need to know
    Richard O Wein
    Department of Otolaryngology Head and Neck Surgery, Tufts Medical Center, Boston, MA 02111, USA
    Neuroimaging Clin N Am 18:551-8, ix. 2008
    ..This article discusses the pertinent issues that surround the current surgical management of parathyroid disease with a focus on epidemiology, surgical anatomy, and operative strategies...
  19. pmc Clinical efficacy and safety of statins in managing cardiovascular risk
    Navin K Kapur
    Division of Cardiology, Tufts University, New England Medical Center, Boston, MA 02111, USA
    Vasc Health Risk Manag 4:341-53. 2008
    ..This review provides a detailed understanding of the clinical efficacy and safety of statins with a particular emphasis on the third generation drug, rosuvastatin...
  20. doi Emotional disclosure through patient narrative may improve pain and well-being: results of a randomized controlled trial in patients with cancer pain
    M Soledad Cepeda
    Department of Anesthesia, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    J Pain Symptom Manage 35:623-31. 2008
    ..Further study is needed to demonstrate whether the implementation of narrative medicine is associated with health benefits in this and other contexts...
  21. pmc Estimating GFR using serum cystatin C alone and in combination with serum creatinine: a pooled analysis of 3,418 individuals with CKD
    Lesley A Stevens
    Division of Nephrology, Tufts New England Medical Center, 750 Washington St, Box 391, Boston, MA 02111, USA
    Am J Kidney Dis 51:395-406. 2008
    ..We report the development and evaluation of GFR-estimating equations using serum cystatin C alone and serum cystatin C, serum creatinine, or both with demographic variables...
  22. ncbi Genetic and hormonal regulation of tryptophan kynurenine metabolism: implications for vascular cognitive impairment, major depressive disorder, and aging
    Gregory F Oxenkrug
    Department of Psychiatry, Tufts University School of Medicine, Boston, MA 02111, USA
    Ann N Y Acad Sci 1122:35-49. 2007
    ....
  23. pmc Neuregulin-1: a potential endogenous protector in perinatal brain white matter damage
    Olaf Dammann
    Division of Newborn Medicine, Department of Pediatrics, Tufts New England Medical Center, Boston, Mass, USA
    Neonatology 93:182-7. 2008
    ..We outline how NRG-1 might be involved in perinatal brain damage pathomechanisms and suggest that NRG-1 might be one target for intervention...
  24. ncbi Wireless on-demand and networking of Puritan Bennett 840 ventilators for direct data capture
    William R Howard
    Department of Respiratory Care, Tufts New England Medical Center, 750 Washington Street T NEMC 785, Boston, MA 02111, USA
    Respir Care 52:1530-41. 2007
    ..I was successful in both the intensive care unit and laboratory environment in transferring ventilator data, for up to several days, and with a data-capture interval as short as 60 seconds...
  25. pmc Perceived socioeconomic status: a new type of identity that influences adolescents' self-rated health
    Elizabeth Goodman
    Tufts New England Medical Center and the Floating Hospital for Children, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    J Adolesc Health 41:479-87. 2007
    ..In addition, the study determines whether SSS independently influences adolescents' self-rated health, an important predictor of morbidity and health service use...
  26. ncbi Extent of right hepatectomy determines postoperative donor albumin and bilirubin changes: new insights
    Roman Schumann
    Department of Anesthesia, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Liver Int 28:95-8. 2008
    ..We conducted a retrospective study to determine whether the size of the liver resection and the estimated blood loss (EBL) impact these laboratory values in the first week (early) and third week (late) postoperatively...
  27. ncbi A randomized placebo-controlled trial of metformin for the treatment of HIV lipodystrophy
    R Kohli
    Division of Geographic Medicine and Infectious Diseases, Tufts New England Medical Center, Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, MA 02111, USA
    HIV Med 8:420-6. 2007
    ....
  28. ncbi The CREB leucine zipper regulates CREB phosphorylation, cardiomyopathy, and lethality in a transgenic model of heart failure
    Gordon S Huggins
    Molecular Cardiology Research Institute, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Am J Physiol Heart Circ Physiol 293:H1877-82. 2007
    ....
  29. ncbi What's more dangerous, your aspirin or your car? Thinking rationally about drug risks (and benefits)
    Joshua T Cohen
    Tufts New England Medical Center, Boston, Massachusetts, USA
    Health Aff (Millwood) 26:636-46. 2007
    ..We discuss the need for the Food and Drug Administration to compare risks and benefits quantitatively, consistently, and explicitly...
  30. pmc The effects of primary care physician visit continuity on patients' experiences with care
    Hector P Rodriguez
    Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, 750 Washington Street, Box 345, Boston, MA 02111, USA
    J Gen Intern Med 22:787-93. 2007
    ..It remains unclear whether PCP visit discontinuity can be planned in a way that is least disruptive to patients' experiences with care...
  31. pmc Idiopathic juxtafoveal retinal telangiectasis: new findings by ultrahigh-resolution optical coherence tomography
    Lelia A Paunescu
    New England Eye Center, Tufts New England Medical Center, Tufts University, Boston, Massachusetts 02111, USA
    Ophthalmology 113:48-57. 2006
    ....
  32. ncbi Gender-based differences in brachial artery flow-mediated vasodilation as an indicator of significant coronary artery disease
    Ayan R Patel
    The Division of Cardiology, Department of Medicine, Tufts New England Medical Center, Boston, Massachusetts, USA
    Am J Cardiol 96:1223-6. 2005
    ..In studies using FMD to evaluate cardiovascular risk, different standards should be applied for women and men...
  33. ncbi The historical and conceptual evolution of radionuclide assessment of myocardial viability
    James E Udelson
    Division of Cardiology, Tufts New England Medical Center, Boston, MA 02111, USA
    J Nucl Cardiol 11:318-34. 2004
  34. ncbi New and dis-improved: on the evaluation and use of less effective, less expensive medical interventions
    David M Kent
    Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Med Decis Making 24:281-6. 2004
    ....
  35. ncbi Description of a clinical pharmacist intervention administered to primary care patients with depression
    Kathleen M Bungay
    The Health Institute, The Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts New England Medical Center, 750 Washington Street, Box 345, Boston, MA 02111, USA
    Gen Hosp Psychiatry 26:210-8. 2004
    ..Research that identifies relationships between the components (active ingredients) of an intervention and the outcomes of care will benefit future intervention strategies and contribute to improved and efficient care...
  36. ncbi In acute ischemic stroke, are asymptomatic intracranial hemorrhages clinically innocuous?
    David M Kent
    Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts New England Medical Center, 750 Washington St, Box 63, Boston, Mass 02111, USA
    Stroke 35:1141-6. 2004
    ..We examined whether the occurrence of an asymptomatic intracranial hemorrhage affects functional outcome in patients with acute ischemic stroke (AIS) treated or not treated with recombinant tissue plasminogen activator (rt-PA)...
  37. ncbi Cranial neuralgias and headaches associated with cranial vascular disorders
    Jeffrey M Chavin
    Department of Neurology, Tufts University School of Medicine, New England Medical Center, 750 Washington Street, Box 314, Boston, MA 02111, USA
    Otolaryngol Clin North Am 36:1079-93, vi. 2003
    ..Also discussed are diagnostic methods, treatment options, and pain management...
  38. ncbi Comparing megestrol acetate therapy with oxandrolone therapy for HIV-related weight loss: similar results in 2 months
    D Mkaya Mwamburi
    Division of Geographic Medicine and Infectious Diseases, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Clin Infect Dis 38:895-902. 2004
    ..74). In conclusion, megestrol acetate therapy and oxandrolone therapy have similar effects on body weight and composition and are safe and well-tolerated during HAART...
  39. ncbi Physician leadership: enhancing the career development of academic physician administrators and leaders
    David G Fairchild
    Division of General Medicine at Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Acad Med 79:214-8. 2004
    ..This article describes how academic medical institutions could enhance the career development of academic physicians in administrative and leadership positions...
  40. ncbi Noninvasive ventilation for chronic obstructive pulmonary disease
    Nicholas S Hill
    Division of Pulmonary, Critical Care, and Sleep Division, Tufts New England Medical Center, 750 Washington Street, 257, Boston MA 02111, USA
    Respir Care 49:72-87; discussion 87-9. 2004
    ..Adherence to NPPV is problematic among patients with severe stable COPD...
  41. ncbi Insulin-like growth factor-1 (IGF-1) and IGF-1 receptor (IGF-1R) expression in human lung in RDS and BPD
    Anne Chetty
    Division of Pulmonology, Department of Pediatrics, Floating Hospital for Children, Tufts New England Medical Center, Boston, Massachusetts, USA
    Pediatr Pulmonol 37:128-36. 2004
    ..IGF-1 and IGF-R expression is low during fetal development, but is acutely upregulated in RDS, and persists with further upregulation in BPD...
  42. ncbi Impact of chronic kidney disease and anemia on hospitalization expense in patients with left ventricular dysfunction
    Douglas D Gregory
    Division of Clinical Decision Making, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Am J Cardiol 92:1300-5. 2003
    ....
  43. ncbi Regulation of glutathione by oxidative stress in bovine pulmonary artery endothelial cells
    Regina M Day
    Pulmonary, Critical Care and Sleep Division, Tufts New England Medical Center, Tupper Research Institute, Department of Medicine, Tufts University, Boston, MA 02111, USA
    Antioxid Redox Signal 5:699-704. 2003
    ..H(2)O(2)-mediated increase in glutathione and activation of ARE binding may play important roles in growth and death of pulmonary artery endothelial cells...
  44. ncbi Extracorporeal photopheresis in the treatment of graft-vs-host disease
    Francine M Foss
    Bone Marrow Transplantation and Experimental Therapeutics, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    J Cutan Med Surg 7:13-7. 2003
  45. ncbi Aspirin and heart failure: square evidence meets a round patient
    Marvin A Konstam
    Division of Cardiology, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Congest Heart Fail 9:203-5. 2003
  46. ncbi Application of the poly-N-acetyl glucosamine-derived rapid deployment hemostat trauma dressing in severe/lethal Swine hemorrhage trauma models
    Raymond J Connolly
    Department of Surgery, New England Medical Center, Boston, Massachusetts 02111, USA
    J Trauma 57:S26-8. 2004
    ..The Rapid Deployment Hemostat (RDH) Bandage was developed for the rapid control of bleeding caused by trauma...
  47. ncbi Cholestasis of pregnancy, pruritus and 5-hydroxytryptamine 3 receptor antagonists
    Roman Schumann
    Department of Anesthesia, Tufts University School of Medicine, Tufts New England Medical Center, Boston, MA 02111, USA
    Acta Obstet Gynecol Scand 83:861-2. 2004
    ....
  48. ncbi Anterior segment complications related to vitreous substitutes
    Rubin W Kim
    Department of Vitreoretinal Surgery, New England Eye Center, Tufts University School of Medicine, 750 Washington Street, Box 450, Boston, MA 02111, USA
    Ophthalmol Clin North Am 17:569-76, vi. 2004
    ..Each of these agents has unique properties, allowing completely different roles of the agents in vitreoretinal surgery. The physical properties, clinical indications, and potential complications of these agents are described...
  49. ncbi Metabolic evaluation of the sick neonate
    Cheryl L Garganta
    Division of Genetics, Department of Pediatrics, Tufts New England Medical Center, Boston, MA 02111, USA
    Semin Perinatol 29:164-72. 2005
    ..Consultation with a metabolic specialist is essential for timely diagnosis and treatment to ensure the best possible outcome...
  50. ncbi Comparison of losartan and captopril on heart failure-related outcomes and symptoms from the losartan heart failure survival study (ELITE II)
    Marvin A Konstam
    Division of Cardiology, Tufts New England Medical Center, Boston, MA 02111, USA
    Am Heart J 150:123-31. 2005
    ..We compared effects of losartan to captopril on mortality, morbidity, and functional status for patients in the ELITE II study...
  51. pmc Cost-related skipping of medications and other treatments among Medicare beneficiaries between 1998 and 2000. Results of a national study
    Ira B Wilson
    The Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, Boston, MA 02111, USA
    J Gen Intern Med 20:715-20. 2005
    ..To report rates of cost-related skipping of medications and other treatments, assess correlates of skipping, examine changes in skipping between 1998 and 2000, and identify factors associated with changes in skipping...
  52. ncbi Images in cardiovascular medicine. Primary lymphoma of the heart
    Jeffrey Kuvin
    Department of Medicine, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA, USA
    Circulation 112:e5-6. 2005
  53. ncbi Prescription drug coverage and seniors: findings from a 2003 national survey
    Dana Gelb Safran
    Health Institute at Tufts New England Medical Center, Boston, USA
    Health Aff (Millwood) . 2005
    ..We discuss MMA's potential to improve quality and the need to monitor performance...
  54. ncbi Behavioral and psychological factors in the assessment and treatment of obesity surgery patients
    Isaac Greenberg
    Obesity Consult Center, Tufts New England Medical Center, 750 Washington Street, Tufts NEMC 900, Boston, MA 02111, USA
    Obes Res 13:244-9. 2005
    ..To provide evidence-based guidelines on the psychological and behavioral screening of weight loss surgery (WLS) candidates and the impact of psychosocial factors on behavior change after gastric bypass surgery...
  55. ncbi Neoaortic aneurysm after stage I Norwood reconstruction
    Afshin Ehsan
    Division of Cardiothoracic Surgery, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Ann Thorac Surg 79:e23-5. 2005
    ..Histologic examination showed a striking accumulation of myxoid material as well as abnormal vasculature in both the native and engrafted portions of the neoaorta...
  56. ncbi Does predialysis nephrology care influence patient survival after initiation of dialysis?
    Samina S Khan
    Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Kidney Int 67:1038-46. 2005
    ....
  57. ncbi Genomic medicine, gene polymorphisms, and human biological diversity
    Vaidyanathapuram S Balakrishnan
    Division of Nephrology, Department of Medicine, Tufts New England Medical Center, Boston, MA 02111, USA
    Semin Dial 18:37-40. 2005
    ..This review provides a broad overview of recent developments in this field, basic information and terminology in common use, and explores the impact of genetic variations or polymorphisms on human biological diversity...
  58. ncbi Comparison of the Atkins, Ornish, Weight Watchers, and Zone diets for weight loss and heart disease risk reduction: a randomized trial
    Michael L Dansinger
    Division of Endocrinology, Diabetes, and Metabolism, Atherosclerosis Research Laboratory, Tufts New England Medical Center, Boston, Mass 02111, USA
    JAMA 293:43-53. 2005
    ....
  59. ncbi Comparison of flow-mediated dilatation of the brachial artery in coronary patients with low-density lipoprotein cholesterol levels <80 mg/dl versus patients with levels 80 to 100 mg/dl
    Jeffrey T Kuvin
    Division of Cardiology, Department of Medicine, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Am J Cardiol 95:93-5. 2005
    ..These data support recent reports that decreasing levels of LDL cholesterol below those currently recommended provides additional benefits and suggest that this benefit may be due in part to increased endothelial function...
  60. ncbi Risk factors for cytomegalovirus viremia and disease developing after prophylaxis in high-risk solid-organ transplant recipients
    Richard B Freeman
    New England Medical Center of Transplant Surgery, Boston, MA 2 Mayo Clinic, Rochester, MN 02111, USA
    Transplantation 78:1765-73. 2004
    ..Cytomegalovirus (CMV) D+/R- solid-organ transplant (SOT) recipients carry increased risk of developing CMV disease; however, other risk factors in these patients have not been delineated...
  61. ncbi Fetomaternal cell traffic, pregnancy-associated progenitor cells, and autoimmune disease
    Diana W Bianchi
    Division of Genetics, Departments of Pediatrics, Obstetrics and Gynecology, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Best Pract Res Clin Obstet Gynaecol 18:959-75. 2004
    ..Recently developed animal models will help to ascertain whether these cells cause disease, respond to disease, or have therapeutic applications...
  62. ncbi Mechanically induced sudden death in chest wall impact (commotio cordis)
    Mark S Link
    Cardiac Arrhythmia Service, New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Prog Biophys Mol Biol 82:175-86. 2003
    ..Activation of the K(+)(ATP) channel is a likely cause of the ventricular fibrillation produced by chest wall blows. Successful resuscitation is attainable with early defibrillation...

Research Grants62

  1. Liver Transplantation for Hepatocellular Carcinoma
    Richard Freeman; Fiscal Year: 2005
    ..Furthermore, these analyses will serve to support future developments of prospective clinical trials. ..
  2. Assisted Patient-Selection for Thrombolytics in Stroke
    David Kent; Fiscal Year: 2007
    ....
  3. Extending Safe and Effective Thrombolysis for Stroke
    David Kent; Fiscal Year: 2005
    ..abstract_text> ..
  4. Kidney Disease, Stroke and Cognitive Impairment
    Daniel Weiner; Fiscal Year: 2007
    ..He has assembled a multidisciplinary team with excellent mentors in an exemplary clinical research environment in order to accomplish the aims of this proposal and develop as an independent clinical researcher. ..
  5. Glycemic Index and Metabolic Syndrome
    ANASTASSIOS PITTAS; Fiscal Year: 2005
    ..abstract_text> ..
  6. Vitamin D Status and Incident Type 2 Diabetes
    ANASTASSIOS PITTAS; Fiscal Year: 2007
    ..We will adjust for potential diabetes confounders (demographic, medical and nutritional) that have been measured and we will also examine whether the association is modified by BMI or calcium intake. ..
  7. The Role of Bone in Osteoarthritis Progression
    Timothy McAlindon; Fiscal Year: 2007
    ..All these data will join and enrich the OAI public data set at specified time points. ..
  8. RESEARCH TRAINING IN RHEUMATOLOGY AT NEW ENGLAND MEDICAL
    Timothy McAlindon; Fiscal Year: 2005
    ..The participation of faculty members and trainees from Adult and Pediatric Rheumatology and Basic Science Departments offers a training opportunity in infection and immunity related to rheumatic diseases. ..
  9. Clinical Research Training in Infectious Diseases
    David Snydman; Fiscal Year: 2007
    ..The goal of this training program will be to develop independent infectious diseases clinical research investigators highly skilled in clinical research methodologies and application. ..
  10. Physician & Scientist Training in Developmental Genetics
    DIANA BIANCHI; Fiscal Year: 2007
    The Developmental Genetics Training Program at Tufts New England Medical Center (T-NEMC) and Tufts University School of Medicine (TUSM) will provide physicians and predoctoral students with strong training in developmental genetics and ..
  11. Neurodevelopmental Outcome in Russian Orphanage
    Laurie Miller; Fiscal Year: 2004
    ..abstract_text> ..
  12. The Role of Tuberin in Smooth Muscle Cell Proliferation
    Geraldine Finlay; Fiscal Year: 2007
    ..abstract_text> ..
  13. Midcareer Investigator Award Patient-Oriented Research
    Ira Wilson; Fiscal Year: 2007
    ..Third, because of the Tufts University Sackler School MS/PhD Program in Clinical Research there is an existing, successful training infrastructure that provides both trainees and junior faculty the opportunity to learn research skills. ..
  14. Genetic Analysis of HIV Complications
    Alexandra Mangili; Fiscal Year: 2007
    ....
  15. Reducing Depression's Impact on Work Performance
    Debra Lerner; Fiscal Year: 2007
    ..This project will provide valuable insights into the feasibility, acceptability and impact of the WHI. Results will also indicate whether further effectiveness testing and translational research are warranted. ..
  16. Tuberin and hamartin in rapamycin-sensitive & rapamycin-insensitive smooth muscle
    Geraldine A Finlay; Fiscal Year: 2010
    ..The purpose of the proposed studies is to improve our understanding of the mechanisms that lead to uncontrolled growth in smooth muscle and to develop new targets for the treatment of pulmonary hypertension. ..
  17. TGF-beta1 and PAI-1 genotypes in Chronic Kidney Disease
    Madhumathi Rao; Fiscal Year: 2007
    ..The proposed training program and research project will prepare her for a career as an independent investigator. ..
  18. Tuberin and hamartin in rapamycin-sensitive & rapamycin-insensitive smooth muscle
    Geraldine Finlay; Fiscal Year: 2009
    ..The purpose of the proposed studies is to improve our understanding of the mechanisms that lead to uncontrolled growth in smooth muscle and to develop new targets for the treatment of pulmonary hypertension. ..
  19. TRH REGULATION/BIOSYNTHESIS AND PARAVENTRICULAR NUCLEUS
    RONALD LECHAN; Fiscal Year: 2007
    ..abstract_text> ..
  20. Genetic Markers of GIK Effect in Acute Coronary Syndrome in the IMMEDIATE Trial
    Inga Peter; Fiscal Year: 2007
    ..End of Abstract) ..
  21. Mitochondiral Injury and Anemia in Elderly Patients with Chornic Kidney Disease
    Madhumathi Rao; Fiscal Year: 2007
    ..There are several therapeutic measures that are known to improve mitochondrial function and biogenesis which may be potentially useful treatments for anemia of chronic disease among elderly patients with declining kidney function. ..
  22. PHEOCHROMOCYTOMAS FROM NEUROFIBROMATOSIS KNOCKOUT MICE
    Arthur Tischler; Fiscal Year: 2003
    ..4) To determine the status of neurofibromin in MPC cells and test the hypothesis that abnormal regulation of ras activity is responsible for neuronal differentiation in this model. ..
  23. CELLULAR INTERACTIONS IN PULMONARY OXYGEN TOXICITY
    ANBUKILI CHETTY; Fiscal Year: 2006
    ..This mentored work will provide extensive education and technical experience in Molecular Biology and the development of a model of hyperoxic lung injury. ..
  24. Myocardial Viability and Remodeling in the OAT
    James Udelson; Fiscal Year: 2007
    ..OAT-NUC is the only viability ancillary study of OAT, and thus serves a critical need in assessing potential mechanisms of the findings in OAT. ..
  25. Coding Audiotapes of Clinic Visits for Adherence Content
    Ira Wilson; Fiscal Year: 2006
    ..While this work focuses on adherence with ARVs for HIV disease, the GMIAS has been designed to be easily generalizable to other conditions and research problems in MD-PT communication. ..
  26. LV Function Assessment Core Lab for IMMEDIATE Trial
    James Udelson; Fiscal Year: 2006
    ..These data Will provide robust information with sufficient power to test the concepts in Hypothesis H9 of the parent trial and provide substantial insights into the mechanism of GIK effect. ..
  27. CHROMAFFIN CELL PROLIFERATION IN NEOPLASTIC PROGRESSION
    Arthur Tischler; Fiscal Year: 2006
    ..The proposed studies will help to elucidate mechanisms that may be involved in the development and progression of pheochromocytomas. ..
  28. TRH and Energy Homeostasis
    RONALD LECHAN; Fiscal Year: 2006
    ..abstract_text> ..
  29. Chronic Kidney Disease, Vascular Disease and Aging
    Mark Sarnak; Fiscal Year: 2007
    ..Three of his previous mentees are currently POR's and members of the Division of Nephrology at Tufts New England Medical Center. His mentees would be supported by a T32 National Research Service Award (NRSA DK007777), as well as ..
  30. CARDIOVASCULAR RISK FACTORS--CHRONIC RENAL INSUFFICIENCY
    Mark Sarnak; Fiscal Year: 2004
    ..The proposed L training program and research project will prepare him for a career as an independent investigator. ..
  31. Health Care Quality and Outcomes in Medicare
    Ira Wilson; Fiscal Year: 2007
    ..The study's findings will address critical questions facing beneficiaries and policymakers as the nation debates Medicare program reform. ..
  32. Homebox Genes in Lung Morphogenesis
    MaryAnn Volpe; Fiscal Year: 2007
    ..The proposed research studies testing these hypothesis will further the understanding of the molecular mechanisms involved in normal lung development and ultimately aid in the creation of new strategies to treat neonatal lung diseases...