Thomas Jefferson University

Summary

Organization: Thomas Jefferson University
Country: USA

Top Publications

  1. doi The spectrum of MR imaging in athletic pubalgia
    Adam C Zoga
    Thomas Jefferson University, 132 South 10th Street, Philadelphia, PA 19107, USA
    Radiol Clin North Am 48:1179-97. 2010
  2. pmc Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer
    Scott A Waldman
    Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, 132 S 10th St, Philadelphia, PA 19107, USA
    JAMA 301:745-52. 2009
  3. doi Lingual abscess from a grill cleaning brush bristle
    Maurits Boon
    Jefferson Medical College, Thomas Jefferson University, Department of Otolaryngology, Philadelphia, Pennsylvania 19107, USA
    Laryngoscope 119:79-81. 2009
  4. doi Effectiveness of a clinical decision support system to identify heparin induced thrombocytopenia
    Jeffrey M Riggio
    Department of Medicine, Jefferson Internal Medicine Associates, Thomas Jefferson University, Philadelphia, PA 19107, USA
    J Thromb Thrombolysis 28:124-31. 2009
  5. doi Noninvasive measurement and screening techniques for spinal deformities
    James S Harrop
    Department of Neurological, Jefferson Medical College, Philadelphia, Pennsylvania, USA
    Neurosurgery 63:46-53. 2008
  6. doi Pregnancy after transplantation
    Vincent T Armenti
    Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Transplant Rev (Orlando) 22:223-40. 2008
  7. doi Analysis and lessons learned instituting an instant messaging reference service at an academic health sciences library: the first year
    Daniel G Kipnis
    Thomas Jefferson University, 1020 Walnut Street, Mezzanine, Philadelphia, PA 19107, USA
    Med Ref Serv Q 27:33-51. 2008
  8. pmc Iron regulatory proteins increase neuronal vulnerability to hydrogen peroxide
    Raymond F Regan
    Department of Emergency Medicine, Thomas Jefferson University, 1020 Sansom Street, Thompson 239, Philadelphia, PA 19107, USA
    Biochem Biophys Res Commun 375:6-10. 2008
  9. doi Invited article: inhibition of B cell functions: implications for neurology
    Marinos C Dalakas
    Neuromuscular Diseases Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Neurology 70:2252-60. 2008
  10. ncbi Proposed strategies for successful clinical management with aripiprazole
    Rajnish Mago
    Thomas Jefferson University, Mood Disorders Program, 833 S Chestnut Street East, Suite 210E, Philadelphia, PA 19107, USA
    Expert Opin Pharmacother 9:1279-90. 2008

Detail Information

Publications62

  1. doi The spectrum of MR imaging in athletic pubalgia
    Adam C Zoga
    Thomas Jefferson University, 132 South 10th Street, Philadelphia, PA 19107, USA
    Radiol Clin North Am 48:1179-97. 2010
    ..This review outlines standard of care, cutting-edge MR imaging techniques for athletic pubalgia, and reviews the spectrum of imaging findings that are encountered in this patient group...
  2. pmc Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer
    Scott A Waldman
    Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, 132 S 10th St, Philadelphia, PA 19107, USA
    JAMA 301:745-52. 2009
    ..Guanylyl cyclase 2C (GUCY2C) is a marker expressed by colorectal tumors that could reveal occult metastases in lymph nodes and better estimate recurrence risk...
  3. doi Lingual abscess from a grill cleaning brush bristle
    Maurits Boon
    Jefferson Medical College, Thomas Jefferson University, Department of Otolaryngology, Philadelphia, Pennsylvania 19107, USA
    Laryngoscope 119:79-81. 2009
    ..1) Describe the clinical presentation of a lingual abscess secondary to a foreign body. 2) Discuss the workup of glossopharyngeal neuralgia (GN). 3) Review existing literature...
  4. doi Effectiveness of a clinical decision support system to identify heparin induced thrombocytopenia
    Jeffrey M Riggio
    Department of Medicine, Jefferson Internal Medicine Associates, Thomas Jefferson University, Philadelphia, PA 19107, USA
    J Thromb Thrombolysis 28:124-31. 2009
    ..Subtle decreases in platelet count may impede timely recognition of heparin-induced thrombocytopenia (HIT), placing the patient at increased risk of thrombotic events...
  5. doi Noninvasive measurement and screening techniques for spinal deformities
    James S Harrop
    Department of Neurological, Jefferson Medical College, Philadelphia, Pennsylvania, USA
    Neurosurgery 63:46-53. 2008
    ..The progression of the scoliotic curve can vary depending on the individual patient, as well as the curve etiology. Noninvasive measurement techniques have been developed to obtain a baseline in addition to record curve progression...
  6. doi Pregnancy after transplantation
    Vincent T Armenti
    Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Transplant Rev (Orlando) 22:223-40. 2008
    ..As the first reported pregnancy after transplantation occurred in a kidney recipient 50 years ago, in March 1958, this review also highlights the first reported pregnancies in other solid organ recipients...
  7. doi Analysis and lessons learned instituting an instant messaging reference service at an academic health sciences library: the first year
    Daniel G Kipnis
    Thomas Jefferson University, 1020 Walnut Street, Mezzanine, Philadelphia, PA 19107, USA
    Med Ref Serv Q 27:33-51. 2008
    In February 2006, Thomas Jefferson University went live with a new instant messaging (IM) service. This paper reviews the first 102 transcripts to examine question types and usage patterns...
  8. pmc Iron regulatory proteins increase neuronal vulnerability to hydrogen peroxide
    Raymond F Regan
    Department of Emergency Medicine, Thomas Jefferson University, 1020 Sansom Street, Thompson 239, Philadelphia, PA 19107, USA
    Biochem Biophys Res Commun 375:6-10. 2008
    ..These results suggest that iron regulatory proteins, particularly IRP2, increase neuronal vulnerability to oxidative injury. Therapies targeting IRP2 binding to ferritin mRNA may attenuate neuronal loss due to oxidative stress...
  9. doi Invited article: inhibition of B cell functions: implications for neurology
    Marinos C Dalakas
    Neuromuscular Diseases Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Neurology 70:2252-60. 2008
    ..In uncontrolled series, benefit has been reported in several disorders. B cell depletion is a well-tolerated therapeutic option currently explored in the treatment of several autoimmune neurologic disorders...
  10. ncbi Proposed strategies for successful clinical management with aripiprazole
    Rajnish Mago
    Thomas Jefferson University, Mood Disorders Program, 833 S Chestnut Street East, Suite 210E, Philadelphia, PA 19107, USA
    Expert Opin Pharmacother 9:1279-90. 2008
    ..Despite its potential clinical benefits, the management of aripiprazole-treated patients can be challenging due to the lack of a simple dosing strategy and guidelines for preventing and managing potential adverse effects...
  11. pmc Overexpression of neprilysin reduces alzheimer amyloid-beta42 (Abeta42)-induced neuron loss and intraneuronal Abeta42 deposits but causes a reduction in cAMP-responsive element-binding protein-mediated transcription, age-dependent axon pathology, and prem
    Kanae Iijima-Ando
    Laboratory of Neurogenetics and Pathobiology, Farber Institute for Neurosciences, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Biol Chem 283:19066-76. 2008
    ..Down-regulation of NEP activity in aging brains may be an evolutionarily conserved phenomenon, which could predispose humans to developing late-onset AD...
  12. doi Medical school programs to increase the rural physician supply: a systematic review and projected impact of widespread replication
    Howard K Rabinowitz
    Department of Family and Community Medicine, Jefferson Medical College, Thomas Jefferson University, Suite 401, 1015 Walnut Street, Philadelphia, PA 19107, USA
    Acad Med 83:235-43. 2008
    ..To systematically review the outcomes of comprehensive medical school programs designed to increase the rural physician supply, and to develop a model to estimate the impact of their widespread replication...
  13. doi Patient-controlled drug delivery for acute postoperative pain management: a review of current and emerging technologies
    Eugene R Viscusi
    Department of Anesthesiology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Reg Anesth Pain Med 33:146-58. 2008
    ..This review will discuss the benefits and drawbacks of both existing and emerging PCA modalities in the context of the ideal PCA system, and provide a critical evaluation of their use in postoperative settings...
  14. ncbi Prognosis after late relapse following epilepsy surgery
    Michael R Sperling
    Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, United States
    Epilepsy Res 78:77-81. 2008
    ..To assess prognosis after late relapse in patients who are seizure free for the first 5 years after epilepsy surgery...
  15. ncbi The physician's response to climate change
    Mona Sarfaty
    Department of Health Policy, Thomas Jefferson University
    Fam Med 41:358-63. 2009
    ....
  16. doi Assessment of "gene-environment" interaction in cases of familial and sporadic pancreatic cancer
    Theresa P Yeo
    Thomas Jefferson University School of Nursing, Edison Building, 130 S 9th Street, Suite 1252, Philadelphia, PA 19107, USA
    J Gastrointest Surg 13:1487-94. 2009
    ..This study characterizes one of the largest national registries of familial PC (FPC) and sporadic PC (SPC), focusing on demographics, clinical factors, self-reported environmental and occupational lifetime exposures, and survival status...
  17. ncbi Stromal caveolin-1 levels predict early DCIS progression to invasive breast cancer
    Agnieszka K Witkiewicz
    Stem Cell Biology and Regenerative Medicine Center, Department of Pathology, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Cancer Biol Ther 8:1071-9. 2009
    ..Thus, determination of stromal Cav-1 levels may be a useful new biomarker for guiding the treatment of ER(+) DCIS patients...
  18. pmc αA-Crystallin associates with α6 integrin receptor complexes and regulates cellular signaling
    A Sue Menko
    Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson School of Medicine, Philadelphia, PA 19107 6799, USA
    Exp Eye Res 91:640-51. 2010
    ..The observed changes in lens cell signaling likely reflect long-term functional adaptations to the absence of the αA-crystallin chaperone/small heat-shock protein...
  19. pmc Troglitazone stimulates beta-arrestin-dependent cardiomyocyte contractility via the angiotensin II type 1A receptor
    Douglas G Tilley
    Department of Pharmaceutical Sciences, Jefferson School of Pharmacy, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Biochem Biophys Res Commun 396:921-6. 2010
    ....
  20. doi High blood pressure in children: clinical and health policy implications
    Bonita Falkner
    Department of Medicine and Pediatrics, Thomas Jefferson University, Philadelphia, PA, USA
    J Clin Hypertens (Greenwich) 12:261-76. 2010
    ..This report aims to increase awareness of the problem of hypertension in childhood. Recent reports on prevalence and target organ injury are discussed and health policy initiatives to improve blood pressure control are proposed...
  21. doi Overview of electrocardiographic findings and clinical presentation of common cardiac arrhythmias
    Cynthia A Sanoski
    Department of Pharmacy Practice, Jefferson School of Pharmacy, Thomas Jefferson University, Philadelphia, PA 19107 5233, USA
    Am J Health Syst Pharm 67:S5-10. 2010
    ..To review the components and interpretation of the 12-lead electrocardiogram (ECG) and compare and contrast the ECG waveforms and clinical presentation associated with major cardiac arrhythmias...
  22. doi Obesity management interventions: a review of the evidence
    Joseph Yaskin
    Jefferson School of Population Health, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Popul Health Manag 12:305-16. 2009
    ..Generally, our results showed that combination approaches-surgical or pharmacologic, combined with a behavioral intervention-were most likely to be effective...
  23. pmc Characterization of cannabinoid-1 receptors in the locus coeruleus: relationship with mu-opioid receptors
    JILLIAN L SCAVONE
    Department of Neurosurgery, Farber Institute for Neurosciences, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Brain Res 1312:18-31. 2010
    ..These data suggest important potential interactions between cannabinoid and opioid systems in LC neuronal profiles that may impact noradrenergic tone...
  24. ncbi Exposure to hydroxyurea and pregnancy outcomes in patients with sickle cell anemia
    Samir K Ballas
    Sickle Cell Center, Cardeza Foundation for Hematologic Research, Jefferson Medical College, 1015 Walnut St, Philadelphia, PA 19107, USA
    J Natl Med Assoc 101:1046-51. 2009
    ..The same argument seems to apply for exposure to opioids. However, it will take a much longer follow-up of many more hydroxyurea-exposed sickle cell disease subjects to establish the results conclusively...
  25. pmc The locus coeruleus: A key nucleus where stress and opioids intersect to mediate vulnerability to opiate abuse
    E J van Bockstaele
    Department of Neurosurgery, Thomas Jefferson University, Farber Institute for Neurosciences, 900 Walnut Street, Suite 400, Philadelphia, PA 19107, USA
    Brain Res 1314:162-74. 2010
    ..Finally, new evidence for novel presynaptic actions of kappa-opioids on LC afferents is provided that adds another dimension to our model of how this central NE system is co-regulated by opioids and stress-related peptides...
  26. pmc Antiviral responses following L-leucyl-L-leucine methyl esther (LLME)-treated lymphocyte infusions: graft-versus-infection without graft-versus-host disease
    Joanne Filicko-O'Hara
    Department of Medical Oncology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Biol Blood Marrow Transplant 15:1609-19. 2009
    ....
  27. doi The elucidation of metabolic pathways and their improvements using stable optimization of large-scale kinetic models of cellular systems
    Evgeni V Nikolaev
    Department of Pathology, Anatomy and Cell Biology, Daniel Baugh Institute for Functional Genomics and Computational Biology, 1020 Locust Street, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Metab Eng 12:26-38. 2010
    ..The source for instability through saddle-node and Hopf bifurcations is identified, and all results are contrasted with predictions from metabolic control analysis...
  28. doi The Jefferson Scale of Physician Empathy: preliminary psychometrics and group comparisons in Italian physicians
    Mariangela Di Lillo
    Center for Research in Medical Education and Health Care, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Acad Med 84:1198-202. 2009
    ..To examine the psychometrics of the Jefferson Scale of Physician Empathy (JSPE) among a sample of Italian physicians...
  29. doi Should enzyme-inducing antiepileptic drugs be considered first-line agents?
    Scott Mintzer
    Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Epilepsia 50:42-50. 2009
    ..Pending this, however, the extant data are sufficiently concerning to suggest that it may be prudent to start with noninducing AEDs unless there is a clear indication for one of the inducing drugs...
  30. doi Measurement and correlates of physicians' lifelong learning
    Mohammadreza Hojat
    Department of Psychiatry and Human Behavior, Center for Research in Medical Education and Health Care, Jefferson Medical College, Philadelphia, Pennsylvania 19107 5083, USA
    Acad Med 84:1066-74. 2009
    ..To examine the psychometric properties and correlates of an instrument to measure physicians' orientation toward lifelong learning with attention to differences between full-time and academic clinicians...
  31. ncbi Malignant pleural effusions: management options with consideration of coding, billing, and a decision approach
    Andrew R Haas
    Interventional Pulmonary Program, Jefferson Medical College of Thomas Jefferson University, Pulmonary and Critical Care Medicine, 834 Walnut St, Sixth Floor, Philadelphia, PA 19107, USA
    Chest 132:1036-41. 2007
    ..This article will provide a general review of MPE management strategies including information concerning coding, billing, documentation, and a decision approach among these various methods...
  32. ncbi Are depression and cognitive performance related in temporal lobe epilepsy?
    Joseph I Tracy
    Department of Neurology, Comprehensive Epilepsy Center, Thomas Jefferson University Hospital Jefferson Medical College, Philadelphia, Pennsylvania 19107, USA
    Epilepsia 48:2327-35. 2007
    ..Temporal lobe epilepsy (TLE) patients are known to possess cognitive dysfunction. Thus, TLE patients who are depressed may suffer a double burden of cognitive deficits...
  33. ncbi Interaction of the nucleotide binding domains and regulation of the ATPase activity of the human retina specific ABC transporter, ABCR
    Esther E Biswas-Fiss
    Department of Bioscience Technologies, Program in Biotechnology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Biochemistry 45:3813-23. 2006
    ..Furthermore, the data support a mechanistic model in which, upon binding of NBD2, NBD1 binds ATP but does not hydrolyze it or does so with a significantly reduced rate...
  34. ncbi Community engagement of men
    Lara Carson Weinstein
    Department of Family and Community Medicine, Jefferson Medical College, Thomas Jefferson University, 833 Chestnut Street Philadelphia, PA 19107, USA
    Prim Care 33:247-59, xi. 2006
  35. ncbi Morbidity and mortality of patients diagnosed with systemic sclerosis after the age of 75: a nested case-control study
    Chris T Derk
    Department of Medicine, Division of Rheumatology, Thomas Jefferson University, Philadelphia, PA, 19017, USA
    Clin Rheumatol 25:831-4. 2006
    ..A higher clinical suspicion will lead to an earlier diagnosis and a potential decrease in morbidity and mortality...
  36. ncbi Elevated mu-opioid receptor expression in the nucleus of the solitary tract accompanies attenuated withdrawal signs after chronic low dose naltrexone in opiate-dependent rats
    E J van Bockstaele
    Department of Neurosurgery, Farber Institute for Neurosciences, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Neurosci Res 83:508-14. 2006
    ....
  37. ncbi Clinical relevance of esophageal and gastric pH measurements in patients with gastro-esophageal reflux disease (GERD)
    Anthony J DiMarino
    Department of Medicine, Division of Gastroenterology and Hepatology, Jefferson Medical College, Philadelphia, PA 19107, USA
    Curr Med Res Opin 21:27-36. 2005
    ..Gastric pH monitoring, on the other hand, is an accurate measure of gastric acid pH, but its relevance to patients with GERD is questionable, since recordings correlate poorly with esophageal acid exposure...
  38. ncbi Plant based HIV-1 vaccine candidate: Tat protein produced in spinach
    Alexander V Karasev
    Biotechnology Foundation Laboratories at Thomas Jefferson University, Department of Microbiology and Immunology, 700 E Butler Avenue, Doylestown, PA 18901, USA
    Vaccine 23:1875-80. 2005
    ..ELISA data suggested that oral Tat primed for the development of Tat antibodies when mice were subsequently vaccinated with plasmid DNA designed for Tat expression...
  39. ncbi Diagnosing Crohn's disease: an economic analysis comparing wireless capsule endoscopy with traditional diagnostic procedures
    Neil I Goldfarb
    Department of Health Policy, Jefferson Medical College, Philadelphia, Pennsylvania 19107, USA
    Dis Manag 7:292-304. 2004
    ..Although not addressed in this model, earlier diagnosis with WCE (due to higher diagnostic yield) also could lead to earlier management, improved quality of life and workplace productivity for people with Crohn's disease...
  40. ncbi Superior labrum, anterior-posterior lesions and biceps injuries: diagnostic and treatment considerations
    Marc I Harwood
    Department of Family Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Prim Care 31:831-55. 2004
    ..The keys to successful treatment are an accurate diagnosis, identification of associated pathologic conditions, and assessment of functional limitations of the injury...
  41. ncbi The effects of niacin on lipoprotein subclass distribution
    John M Morgan
    Thomas Jefferson University, Jefferson Heart Institute, Sidney Kimmel Laboratory for Preventive Medicine, 925 Chestnut Street, 1st Floor, Philadelphia, PA 19107, USA
    Prev Cardiol 7:182-7; quiz 188. 2004
    ..In addition, it also tends to decrease concentrations of the larger very-low-density lipoprotein subclasses. Niacin confers diverse benefits with respect to both the quantity and quality of lipid and lipoprotein particles...
  42. ncbi Differences in peripheral noradrenergic function among actively drinking and abstinent alcohol-dependent individuals
    Ashwin A Patkar
    Department of Psychiatry and Human Behavior, Thomas Jefferson University, Philadelphia, PA, USA
    Am J Addict 13:225-35. 2004
    ..However, the changes in NA activity appears to normalize after a longer period of abstinence. Alterations in NA activity do not seem to be specific for Type I or Type II subtypes of alcoholism...
  43. ncbi Summary of the Fourth Report on the Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents
    Bonita Falkner
    Department of Medicine, Thomas Jefferson University, Philadelphia, PA, USA
    Hypertension 44:387-8. 2004
  44. ncbi Phosphoinositide deficiency due to inositol depletion is not a mechanism of lithium action in brain
    Gerard T Berry
    Children s Research Institute, Children s National Medical Center, Department of Pediatrics, George Washington University School of Medicine and Health Sciences, Washington, DC, USA
    Mol Genet Metab 82:87-92. 2004
    ..We conclude that PtdIns deficiency due to "inositol depletion" is not a mechanism of lithium action in brain, and that Ins plays another unidentified role in the mammalian brain...
  45. ncbi Double trisomy (48,XXY,+21) in monozygotic twins: case report and review of the literature
    Dimitrios Iliopoulos
    Laboratory of Cytogenetics, 2nd Department of Pediatrics, A H E P A Hospital, School of Medicine, Aristotelian University of Thessaloniki, Thessaloniki, Greece
    Ann Genet 47:95-8. 2004
    ..The purpose of this report is to present a rare case of possible coincidence of double aneuploidy in newborn twins. A review of the literature showed that double trisomy (48,XXY,+21) in a twin newborn infant has never occurred...
  46. ncbi Relationships between self-assessment skills, test performance, and demographic variables in psychiatry residents
    David J Lynn
    Department of Psychiatry, Thomas Jefferson University, 1020 Sansom Street Suite 1652, Philadelphia, Pennsylvania 19107 5004, USA
    Adv Health Sci Educ Theory Pract 11:51-60. 2006
    ..In addition, we found no resident characteristics that accounted for variation in self-assessment accuracy...
  47. ncbi Ca2+-dependent control of the permeability properties of the mitochondrial outer membrane and voltage-dependent anion-selective channel (VDAC)
    Gyorgy Bathori
    Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Biol Chem 281:17347-58. 2006
    ..Thus, the VDAC gating is dependent on the physiological concentrations of cations, allowing the OMM to control the passage of ions and some small molecules. The OMM barrier is likely to decrease during the calcium signal...
  48. ncbi Developing and sustaining a web-based library newsletter
    Anthony J Frisby
    Scott Memorial Library, Thomas Jefferson University, 1020 Walnut St, Philadelphia, PA 19107, USA
    Med Ref Serv Q 25:17-25. 2006
    ..By identifying the most successful strategies, and reflecting on the lessons learned along way, the authors hope to continue the evolution of the Forum and help to ensure the viability of the library newsletter...
  49. ncbi Menstrual migraine: a review of hormonal causes, prophylaxis and treatment
    Avi Ashkenazi
    Thomas Jefferson University, Department of Neurology, Philadelphia, PA 19107, USA
    Expert Opin Pharmacother 8:1605-13. 2007
    ..Women who suffer from frequent or debilitating MM attacks may benefit from perimenstrual prophylaxis that can be either hormonal or non-hormonal...
  50. ncbi Reproducibility of platelet function testing
    Megan E Hevelow
    Cardeza Foundation for Hematologic Research, Thomas Jefferson University, Philadelphia, PA, USA
    Lab Hematol 13:59-62. 2007
    ..The significance of an abnormal result in initial testing of a patient will depend on understanding this variation...
  51. ncbi A dying art?: The doctor's letter of condolence
    Gregory C Kane
    Jefferson Medical College, Division of Pulmonary and Critical Care Medicine, Jefferson University Hospital, 1025 Walnut St, No 805, Philadelphia, PA 19107 5083, USA
    Chest 131:1245-7. 2007
  52. ncbi Early invasive cervical cancer: tumor delineation by magnetic resonance imaging, computed tomography, and clinical examination, verified by pathologic results, in the ACRIN 6651/GOG 183 Intergroup Study
    Donald G Mitchell
    Department of Radiology, Thomas Jefferson University, Philadelphia, PA, USA
    J Clin Oncol 24:5687-94. 2006
    ..To compare magnetic resonance imaging (MRI), computed tomography (CT), and clinical examination for delineating early cervical cancer and for measuring tumor size...
  53. ncbi Long-term gene expression in dividing and nondividing cells using SV40-derived vectors
    David S Strayer
    Department of Pathology and Cell Biology, Jefferson Medical College, Philadelphia, PA, USA
    Mol Biotechnol 34:257-70. 2006
    ....
  54. ncbi Information literacy and library attitudes of occupational therapy students
    Daniel G Kipnis
    Scott Memorial Library, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Med Ref Serv Q 25:11-20. 2006
    ..the results of an information literacy survey presented to occupational therapy (OT) students at Thomas Jefferson University during a series of required class activities...
  55. ncbi Effect of simultaneous inhibition of epidermal growth factor receptor and cyclooxygenase-2 in HER-2/neu-positive breast cancer
    Susan Lanza-Jacoby
    Department of Surgery, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Clin Cancer Res 12:6161-9. 2006
    ..This study investigated whether simultaneously blocking both EGFR and COX-2 pathways with ZD1839 and celecoxib, respectively, would be more effective in inhibiting cell growth and inducing apoptosis than either agent alone...
  56. pmc The development of a laparoscopic donor nephrectomy program in a de novo renal transplant program: Evolution of technique and results in over 200 cases
    Costas D Lallas
    Department of Urology, Mayo Clinic, Scottsdale, Arizona, USA
    JSLS 10:135-40. 2006
    ..From the onset, donor nephrectomies were performed laparoscopically and are currently the domain of Urology, which had no prior laparoscopic experience before this undertaking. We reviewed our experience...
  57. ncbi Secretory phospholipase A2 levels in patients with sickle cell disease and acute chest syndrome
    Samir K Ballas
    Thomas Jefferson University, Philadelphia, PA 19107, USA
    Hemoglobin 30:165-70. 2006
    ..00 AU at any point in time during follow-up. The data indicate that the reliability of sPLA(2( for predicting the development of ACS is not perfect (100%) as was previously reported but occurs in about 80% of the patients...
  58. ncbi EEG reading session
    Michael R Sperling
    Department of Neurology, Thomas Jefferson University, Jefferson Comprehensive Epilepsy Center, Philadelphia, Pennsylvania 19107, USA
    J Clin Neurophysiol 23:230-7. 2006
  59. ncbi Massive fetal ileal duplication requiring antenatal intervention
    Amen Ness
    Department of Obstetrics and Gynecology, Jefferson Medical College, Thomas Jefferson University, 834 Chestnut St, Suite 400, Philadelphia, PA 19107, USA
    J Ultrasound Med 25:785-90. 2006
  60. ncbi A randomized trial of a multicomponent home intervention to reduce functional difficulties in older adults
    Laura N Gitlin
    Center for Applied Research on Aging and Health, Thomas Jefferson University, 130 S 9th Street, Philadelphia, PA 19130, USA
    J Am Geriatr Soc 54:809-16. 2006
    ..To test the efficacy of a multicomponent intervention to reduce functional difficulties, fear of falling, and home hazards and enhance self-efficacy and adaptive coping in older adults with chronic conditions...
  61. ncbi The epidemiology and diagnosis of insomnia
    Karl Doghramji
    Sleep Disorders Center, Thomas Jefferson University, 1015 Walnut Street, Suite 319, Philadelphia, PA 19107, USA
    Am J Manag Care 12:S214-20. 2006
    ..This article will provide an overview of insomnia, its prevalence and epidemiology, and guidelines for clinical assessment...
  62. ncbi Gene transfer in experimental medicine
    Gaetano Romano
    Department of Neurosurgery, The Farber Institute for the Neurosciences, Jefferson Medical College, Thomas Jefferson University, Jefferson Hospital for the Neurosciences, 900 Walnut Street Suite 422, Philadelphia, PA 19107, USA
    Drug News Perspect 16:267-76. 2003
    ..This review summarizes the latest achievements and controversies in clinical trials and preclinical studies in the field of gene therapy...

Research Grants62

  1. ENHANCING FUNCTION OF FRAIL ELDERS BY MODIFYING THE HOME
    Laura Gitlin; Fiscal Year: 2003
    ..abstract_text> ..
  2. Multisite Intervention Trial for Diverse Caregivers
    Laura Gitlin; Fiscal Year: 2003
    ..A uniform battery of predictor and outcome measures will be collected at baseline, three and six months. Cost-effectiveness and clinical significance of the two conditions will also be evaluated. ..
  3. Treating Depression in African American Elders: A Community-Academic Partnership
    Laura N Gitlin; Fiscal Year: 2010
    ..Based on a strong collaborative partnership between an academic research center at Thomas Jefferson University, and a senior center, Center in the Park (CIP), we plan to test the effectiveness of an in-home ..
  4. RESEARCH PROGRAM TO PROMOTE OPTIMAL AGING IN PLACE
    Laura Gitlin; Fiscal Year: 2004
    ..to advance the research and training capacity in aging of the newly formed Senior Health Institute of Thomas Jefferson University (TJU) and the Jefferson Health System (JHS)...
  5. Supporting Mental Health of African American Elders
    Laura Gitlin; Fiscal Year: 2007
    ..partnership between a research center (Center for Applied Research on Aging and Health, CARAH) at Thomas Jefferson University, and a senior center in the Philadelphia Region, Center in the Park (CIP)...
  6. Treating Depression in African American Elders: A Community-Academic Partnership
    Laura Gitlin; Fiscal Year: 2007
    ..Based on a strong collaborative partnership between an academic research center at Thomas Jefferson University, and a senior center, Center in the Park (CIP), we plan to test the effectiveness of an in-home ..
  7. Tailored Activity to Improve Affect in Dementia at Home
    Laura Gitlin; Fiscal Year: 2006
    ..This pilot study will provide critical data by which to refine and standardize the intervention manual and protocols, and structure the design of a large-scale randomized clinical trial. ..
  8. Reducing Family Caregiver Upset with Disruptive Behavior
    Laura Gitlin; Fiscal Year: 2005
    ....
  9. Treating Depression in African American Elders: A Community-Academic Partnership
    Laura Gitlin; Fiscal Year: 2009
    ..Based on a strong collaborative partnership between an academic research center at Thomas Jefferson University, and a senior center, Center in the Park (CIP), we plan to test the effectiveness of an in-home ..
  10. Subharmonic Microbubble Signals for Pressure Estimation
    Flemming Forsberg; Fiscal Year: 2007
    ..This will allow potentially life-threatening diseases, such as increased pressure in the liver, to be diagnosed early. ..
  11. Quantitative Subharmonic Breast Imaging
    Flemming Forsberg; Fiscal Year: 2010
    ..This study will be conducted jointly at Thomas Jefferson University and at the University of California, San Diego...
  12. Contrast-Enhanced Ultrasound Detection of Angiogenesis
    Flemming Forsberg; Fiscal Year: 2004
    ..If successful, this project will permit non-invasive ultrasound evaluations of anti-angiogenic tumor therapies in animals as well as humans. ..
  13. Environment and Gene Effects on Brain and Behavior
    Jay Schneider; Fiscal Year: 2009
    ....
  14. Clinical Center: Parkinson's Disease Neuroprotection Trial
    Jay Schneider; Fiscal Year: 2007
    ..The lead site will be Thomas Jefferson University (Parkinson's Disease Research Unit), with satellite sites at Main Line Health Hospitals in Bryn Mawr, ..
  15. Nicotine and Cognition in Parkinsonism
    Jay Schneider; Fiscal Year: 2007
    ..Information obtained from these studies will hopefully lead to more efficient design of nicotinic therapeutics for patients with a variety of cognitive disorders. ..
  16. Attention and Executive Functioning in Aging and Parkisonism
    Jay Schneider; Fiscal Year: 2009
    ....
  17. GM1 Ganglioside Effects on Parkinson's Disease
    Jay Schneider; Fiscal Year: 2007
    ..Working hypothesis: Long-term GM1 use will stabilize symptoms or slow the progression of symptoms in PD patients and this may be accompanied by reduced loss of striatal DA terminals over time. ..
  18. Attention and Executive Functioning in Aging and Parkisonism
    Jay S Schneider; Fiscal Year: 2010
    ....
  19. Environment and Gene Effects on Brain and Behavior
    Jay S Schneider; Fiscal Year: 2010
    ....
  20. GM1 GANGLIOSIDE EFFECTS ON PARKINSONS DISEASE
    Jay Schneider; Fiscal Year: 2003
    ....
  21. Nicotine and Cognition in Parkinsonism
    Jay Schneider; Fiscal Year: 2005
    ..abstract_text> ..
  22. Model Systems for PXE
    Jouni Uitto; Fiscal Year: 2010
    ..The results are expected to provide novel approaches to ameliorate, and perhaps cure, PXE and other related, currently intractable, mineralization disorders. ..
  23. TGF-Beta, Glucose and Nephropathy in African Americans
    Bonita Falkner; Fiscal Year: 2007
    ..abstract_text> ..
  24. COLLAGEN BIOSYNTHESIS OF CULTURED FIBROBLASTS
    Jouni Uitto; Fiscal Year: 2006
    ....