Sriram Yennu

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. pmc Effects of Dexamethasone and Placebo on Symptom Clusters in Advanced Cancer Patients: A Preliminary Report
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Oncologist 21:384-90. 2016
  2. doi High-Dose Asian Ginseng (Panax Ginseng) for Cancer-Related Fatigue: A Preliminary Report
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Integr Cancer Ther 14:419-27. 2015
  3. doi Reduction of cancer-related fatigue with dexamethasone: a double-blind, randomized, placebo-controlled trial in patients with advanced cancer
    Sriram Yennurajalingam
    The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    J Clin Oncol 31:3076-82. 2013
  4. pmc Factors associated with the severity and improvement of fatigue in patients with advanced cancer presenting to an outpatient palliative care clinic
    Sriram Yennu
    Department of Palliative Care and Rehabilitation Medicine, Unit 1414, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, USA
    BMC Palliat Care 11:16. 2012
  5. pmc The role of thalidomide and placebo for the treatment of cancer-related anorexia-cachexia symptoms: results of a double-blind placebo-controlled randomized study
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Palliat Med 15:1059-64. 2012
  6. doi The impact of an outpatient palliative care consultation on symptom burden in advanced prostate cancer patients
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Palliat Med 15:20-4. 2012
  7. doi Association between fatigue and other cancer-related symptoms in patients with advanced cancer
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Unit 008, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Support Care Cancer 16:1125-30. 2008
  8. doi Characteristics of family conferences in a palliative care unit at a comprehensive cancer center
    Sriram Yennurajalingam
    Palliative Care and Rehabilitation Medicine, MD Anderson Cancer Center, Houston, Texas 77030, USA
    J Palliat Med 11:1208-11. 2008
  9. doi Challenges associated with spinal opioid therapy for pain in patients with advanced cancer: a report of three cases
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 39:930-5. 2010
  10. pmc Factors associated with response to methylphenidate in advanced cancer patients
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, Unit 008, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Oncologist 16:246-53. 2011

Collaborators

Detail Information

Publications45

  1. pmc Effects of Dexamethasone and Placebo on Symptom Clusters in Advanced Cancer Patients: A Preliminary Report
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Oncologist 21:384-90. 2016
    ..Our objective was to examine the effects of dexamethasone on symptom clusters in patients with advanced cancer...
  2. doi High-Dose Asian Ginseng (Panax Ginseng) for Cancer-Related Fatigue: A Preliminary Report
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Integr Cancer Ther 14:419-27. 2015
    ..The number and efficacy of available treatments for CRF are limited. The objective of this preliminary study was to assess the safety of high-dose Panax ginseng (PG) for CRF...
  3. doi Reduction of cancer-related fatigue with dexamethasone: a double-blind, randomized, placebo-controlled trial in patients with advanced cancer
    Sriram Yennurajalingam
    The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    J Clin Oncol 31:3076-82. 2013
    ..The primary objective of this prospective, randomized, double-blind, placebo-controlled study was to compare the effect of dexamethasone and placebo on CRF...
  4. pmc Factors associated with the severity and improvement of fatigue in patients with advanced cancer presenting to an outpatient palliative care clinic
    Sriram Yennu
    Department of Palliative Care and Rehabilitation Medicine, Unit 1414, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, USA
    BMC Palliat Care 11:16. 2012
    ....
  5. pmc The role of thalidomide and placebo for the treatment of cancer-related anorexia-cachexia symptoms: results of a double-blind placebo-controlled randomized study
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Palliat Med 15:1059-64. 2012
    ..To determine the effects of thalidomide and placebo on anorexia-cachexia and its related symptoms, body composition, resting metabolic rate, and serum cytokines and their receptors in patients with advanced cancer...
  6. doi The impact of an outpatient palliative care consultation on symptom burden in advanced prostate cancer patients
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Palliat Med 15:20-4. 2012
    ..The aim of this retrospective study was to describe the impact of an outpatient palliative care (PC) consultation on symptoms in patients with advanced prostate cancer...
  7. doi Association between fatigue and other cancer-related symptoms in patients with advanced cancer
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Unit 008, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Support Care Cancer 16:1125-30. 2008
    ....
  8. doi Characteristics of family conferences in a palliative care unit at a comprehensive cancer center
    Sriram Yennurajalingam
    Palliative Care and Rehabilitation Medicine, MD Anderson Cancer Center, Houston, Texas 77030, USA
    J Palliat Med 11:1208-11. 2008
    ..The purpose of our study was to obtain preliminary information on the characteristics of family conferences that take place in an inpatient palliative care unit (PCU)...
  9. doi Challenges associated with spinal opioid therapy for pain in patients with advanced cancer: a report of three cases
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 39:930-5. 2010
    ....
  10. pmc Factors associated with response to methylphenidate in advanced cancer patients
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, Unit 008, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Oncologist 16:246-53. 2011
    ..Our objective of this study was to identify the specific patient characteristics associated with response to methylphenidate and to compare day 1 response with day 8 response...
  11. ncbi The impact of the palliative care mobile team on symptom assessment and medication profiles in patients admitted to a comprehensive cancer center
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Support Care Cancer 15:471-5. 2007
    ..However, the availability of such information is limited. The purpose of our study was therefore to describe the experience of a palliative care team at our comprehensive cancer center...
  12. pmc Methylphenidate and/or a nursing telephone intervention for fatigue in patients with advanced cancer: a randomized, placebo-controlled, phase II trial
    Eduardo Bruera
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 31:2421-7. 2013
    ..The effect of a combined intervention including MP plus a nursing telephone intervention (NTI) was also assessed...
  13. pmc Timing of palliative care referral and symptom burden in phase 1 cancer patients: a retrospective cohort study
    David Hui
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 116:4402-9. 2010
    ..In the current study, the timing of referral and symptom burden between patients referred to palliative care by phase 1 oncologists and those referred by non-phase 1 oncologists were compared...
  14. doi Clinical response to an outpatient palliative care consultation in patients with advanced cancer and cancer pain
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 44:340-50. 2012
    ..There is limited published data regarding the outcomes of palliative care consult on cancer pain treatment at the first follow-up visit...
  15. pmc Early referral to supportive care specialists for symptom burden in lung cancer patients: a comparison of non-Hispanic whites, Hispanics, and non-Hispanic blacks
    Cielito C Reyes-Gibby
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Cancer 118:856-63. 2012
    ..This study assessed whether the timing of referral to the Supportive Care Center (SCC) and symptom burden outcome varied by race or ethnicity in lung cancer patients who had been seen at a tertiary cancer center...
  16. pmc Role of inflammation gene polymorphisms on pain severity in lung cancer patients
    Cielito C Reyes-Gibby
    Department of Epidemiology, Division of Cancer Prevention, The University of Texas M D Anderson Cancer Center, Unit 1340, 1155 Pressler Street, Houston, TX 77030 4009, USA
    Cancer Epidemiol Biomarkers Prev 18:2636-42. 2009
    ..This study suggests the importance of inflammation gene polymorphisms in modulating pain severity. Additional studies are needed to validate our findings...
  17. pmc Use of Palliative Care Services in a Tertiary Cancer Center
    Shalini Dalal
    Department of Palliative Care and Rehabilitation Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Oncologist 21:110-8. 2016
    ..This study was conducted to determine the use of PC/SC service over the past 8 years...
  18. pmc Clinical characteristics of cancer patients referred early to supportive and palliative care
    Jung Hye Kwon
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    J Palliat Med 16:148-55. 2013
    ..We compared clinical characteristics between patients referred late in the course of their disease (late referrals, LRs) with patients referred earlier (early referrals, ERs)...
  19. doi Association between serum cortisol and testosterone levels, opioid therapy, and symptom distress in patients with advanced cancer
    Rony Dev
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 41:788-95. 2011
    ..Patients with advanced cancer often experience symptoms such as pain, anorexia, and fatigue. Opioid therapy for the management of cancer pain may result in neurohormonal dysfunction that may contribute to a patient's symptom burden...
  20. ncbi Errors in symptom intensity self-assessment by patients receiving outpatient palliative care
    Anil Garyali
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas, M D Anderson Cancer Center, Houston, 77030, USA
    J Palliat Med 9:1059-65. 2006
    ..The Edmonton Symptom Assessment Scale (ESAS) is a reliable and valid assessment tool routinely used for symptom intensity assessment in our cancer center...
  21. doi Delirium with severe symptom expression related to hypercalcemia in a patient with advanced cancer: an interdisciplinary approach to treatment
    Marvin Omar Delgado-Guay
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 36:442-9. 2008
    ....
  22. pmc Discharge outcomes and survival of patients with advanced cancer admitted to an acute palliative care unit at a comprehensive cancer center
    David Hui
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    J Palliat Med 13:49-57. 2010
    ..Acute palliative care units (APCUs) are new programs aimed at integrating palliative and oncology care. Few outcome studies from APCUs are available...
  23. pmc Attrition rates, reasons, and predictive factors in supportive care and palliative oncology clinical trials
    David Hui
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Cancer 119:1098-105. 2013
    ..In the current study, the authors' objective was to determine the rate, reasons, and factors associated with attrition both before reaching the primary endpoint and at the end of the study...
  24. doi Neuroleptic dose in the management of delirium in patients with advanced cancer
    David Hui
    Department of Palliative Care and Rehabilitation Medicine, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 39:186-96. 2010
    ..Future studies should examine the efficacy of neuroleptic dose according to individual delirium symptoms...
  25. pmc The Frequency, Characteristics, and Outcomes Among Cancer Patients With Delirium Admitted to an Acute Palliative Care Unit
    Maxine De la Cruz
    Department of Palliative Care and Rehabilitation Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Oncologist 20:1425-31. 2015
    ..In this study, we examined the frequency, characteristics, and outcomes of delirium in patients with advanced cancer admitted to an APCU...
  26. doi Association between self-reported sleep disturbance and other symptoms in patients with advanced cancer
    Marvin Delgado-Guay
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 41:819-27. 2011
    ..Sleep disturbance (SD) is a significant source of distress for patients with cancer. Studies of patients with advanced cancer receiving palliative care to identify symptoms associated with the severity of SD are limited...
  27. doi Perception of Helpfulness of a Question Prompt Sheet Among Cancer Patients Attending Outpatient Palliative Care
    Joseph Arthur
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer, Houston, Texas, USA Electronic address
    J Pain Symptom Manage 53:124-130.e1. 2017
    ..Our team previously developed a single-page QPS using a Delphi process. The main objective of this study was to determine the perception of helpfulness of a QPS in patient-physician communication among advanced cancer outpatients...
  28. pmc Minimal clinically important differences in the Edmonton Symptom Assessment Scale in cancer patients: A prospective, multicenter study
    David Hui
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas
    Cancer 121:3027-35. 2015
    ..A sensitivity-specificity approach was used to identify the minimal clinically important difference (MCID) for improvement and deterioration for each of the 10 ESAS symptoms...
  29. pmc Predictors of response to palliative care intervention for chronic nausea in advanced cancer outpatients
    Wadih Rhondali
    Department of Palliative Care and Rehabilitation Medicine, Unit 141, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Support Care Cancer 21:2427-35. 2013
    ..Nausea is a frequent and distressing symptom in advanced cancer patients. The objective of this retrospective study was to determine predictors of response to palliative care consultation for chronic nausea in advanced cancer outpatients...
  30. pmc Characteristics of advanced cancer patients with cancer-related fatigue enrolled in clinical trials and patients referred to outpatient palliative care clinics
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Pain Symptom Manage 45:534-41. 2013
    ..Limited published data exist on whether characteristics of patients with advanced cancer enrolled in cancer-related fatigue clinical trials (CCTs) differ from patients in outpatient palliative care clinics (OPCs)...
  31. pmc Palliative care in advanced cancer patients: how and when?
    Eduardo Bruera
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
    Oncologist 17:267-73. 2012
    ....
  32. ncbi Pain and terminal delirium research in the elderly
    Sriram Yennurajalingam
    Department of Symptom Control and Palliative Care, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 8, Houston, TX 77030 4095, USA
    Clin Geriatr Med 21:93-119, viii. 2005
    ..This article highlights new developments in assessment and management of pain and delirium...
  33. ncbi Intractable pain: intoxication or undermedication?
    Badi El Osta
    Department of Palliative Care and Rehabilitation Medicine, Division of Cancer Medicine, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Palliat Med 10:811-4. 2007
  34. doi Could Objective Tests Be Used to Measure Fatigue in Patients with Advanced Cancer?
    Gustavo Schvartsman
    Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    J Pain Symptom Manage . 2017
    ..Assessment of cancer-related fatigue is currently based on patient-reported outcomes. We asked whether objective assessments such as muscle strength and nutritional markers can be used as surrogate measures of cancer-related fatigue...
  35. doi The impact of a simplified documentation method for the Edmonton classification system for cancer pain (ECS-CP) on clinician utilization
    Kimberson Tanco
    Department of Palliative Care, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd Unit 1414, Houston, TX, 77030, USA
    Support Care Cancer 25:575-580. 2017
    ..The objectives of this study were to determine the rate of clinician documentation and completion of the ECS-CP features after revision and simplification of the response for each feature...
  36. pmc Genetic variations in interleukin-8 and interleukin-10 are associated with pain, depressed mood, and fatigue in lung cancer patients
    Cielito C Reyes-Gibby
    Department of Emergency Medicine, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Pain Symptom Manage 46:161-72. 2013
    ..A report by the National Cancer Institute identified that an important gap in symptom research is the investigation of multiple symptoms of cancer that might identify common biological mechanisms among cancer-related symptoms...
  37. pmc A multicenter survey of Hispanic caregiver preferences for patient decision control in the United States and Latin America
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Palliat Med 27:692-8. 2013
    ..The family caregiver has an important role in a patient's decisional role preferences. There are limited studies on family caregivers' preferences of the patient's decision control at the end of life among Hispanics...
  38. pmc Frequency, outcome, and predictors of success within 6 weeks of an opioid rotation among outpatients with cancer receiving strong opioids
    Akhila Reddy
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer, Houston, TX 77030, USA
    Oncologist 18:212-20. 2013
    ..Opioid rotation is used to treat uncontrolled pain and/or opioid-related adverse effects. Our aim was to determine the frequency, indications, outcomes, and predictors of successful opioid rotation in outpatients with cancer...
  39. pmc Genetic and nongenetic covariates of pain severity in patients with adenocarcinoma of the pancreas: assessing the influence of cytokine genes
    Cielito C Reyes-Gibby
    Department of Epidemiology, Division of Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    J Pain Symptom Manage 38:894-902. 2009
    ..23, 95% CI=1.4, 4.7) for severe pain relative to the AA genotypes. We provide preliminary evidence of the role of IL-8 in the severity of pain in pancreatic cancer patients. Additional studies are needed in larger cohorts of patients...
  40. ncbi Palliative management of fatigue at the close of life: "it feels like my body is just worn out"
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    JAMA 297:295-304. 2007
    ....
  41. pmc Clinical signs of impending death in cancer patients
    David Hui
    Departments of Palliative Care and Rehabilitation Medicine and Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA Department of Palliative Care, Barretos Cancer Hospital, Barretos, Brazil Division of Biostatistics, University of Texas Health Science Center at Houston, Houston, Texas, USA Programa Medicina Paliativa, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Oncologist 19:681-7. 2014
    ..A better understanding of these signs may improve the ability of clinicians to diagnose impending death. We examined the frequency and onset of 10 bedside physical signs and their diagnostic performance for impending death...
  42. pmc The accuracy of probabilistic versus temporal clinician prediction of survival for patients with advanced cancer: a preliminary report
    David Hui
    Department of Palliative Care and Rehabilitation Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Oncologist 16:1642-8. 2011
    ..The probabilistic approach was associated with high accuracy and has practical implications...
  43. pmc "Whatever my mother wants": barriers to adequate pain management
    Akhila Reddy
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    J Palliat Med 16:709-12. 2013
    ..This case highlights the importance of understanding and addressing fears regarding opioid use and implementing an integrated approach including oncologists and palliative care physicians, along with early referrals to palliative care...
  44. pmc Post-Discharge Survival Outcomes of Patients with Advanced Cancer from the University of Texas MD Anderson Cancer Center Investigational Cancer Therapeutics (Phase I Trials) Inpatient Unit
    Holly Kinahan
    Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Oncology 92:14-20. 2017
    ..Due to their aggressive disease and complex comorbid conditions, these patients often need inpatient admission. This study assessed the outcomes of such patients after they were discharged to hospice care...
  45. doi The frequency of missed delirium in patients referred to palliative care in a comprehensive cancer center
    Maxine De la Cruz
    MD Anderson Cancer Center, University of Texas, Houston, TX, USA
    Support Care Cancer 23:2427-33. 2015
    ..The aim of our study is to determine at the frequency of missed delirium (MD) and identify factors associated with MD...