Henry K Wong

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi request reprint Novel biomarkers, dysregulated epigenetics, and therapy in cutaneous T-cell lymphoma
    Henry K Wong
    Division of Dermatology, Department of Internal Medicine, The Ohio State University, Gahanna, OH 43230, USA
    Discov Med 16:71-8. 2013
  2. pmc Evolving insights in the pathogenesis and therapy of cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome)
    Henry K Wong
    Division of Dermatology, The Ohio State University, Columbus, OH 43221, USA
    Br J Haematol 155:150-66. 2011
  3. pmc Primary Cutaneous B-Cell Lymphoma: Management and Patterns of Recurrence at the Multimodality Cutaneous Lymphoma Clinic of The Ohio State University
    Brad Haverkos
    Comprehensive Cancer Center, Department of Pathology, Division of Hematology, Department of Medicine, Division of Dermatology, Department of Medicine, Center for Biostatistics, and Department of Radiation Oncology, The Ohio State University, Columbus, Ohio, USA Department of Dermatology, University of Arkansas for Medical Sciences, College of Medicine, Little Rock, Arkansas, USA
    Oncologist 20:1161-6. 2015
  4. doi request reprint Promoter-Specific Hypomethylation Is Associated with Overexpression of PLS3, GATA6, and TWIST1 in the Sezary Syndrome
    Henry K Wong
    1 Division of Dermatology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA 2 The Comprehensive Cancer Center and The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio, USA
    J Invest Dermatol 135:2084-92. 2015
  5. pmc Impaired proteasome function activates GATA3 in T cells and upregulates CTLA-4: relevance for Sézary syndrome
    Heather M Gibson
    Division of Dermatology, The Ohio State University, Columbus, OH, USA
    J Invest Dermatol 133:249-57. 2013
  6. pmc Promoter methylation regulates SAMHD1 gene expression in human CD4+ T cells
    Suresh de Silva
    Center for Retrovirus Research, Department of Veterinary Biosciences, The OhioState University, Columbus, OH 43210, USA
    J Biol Chem 288:9284-92. 2013
  7. doi request reprint Remission of psoriasis after allogeneic, but not autologous, hematopoietic stem-cell transplantation
    Benjamin H Kaffenberger
    Dermatology, Ohio State University College of Medicine, Columbus, Ohio 43216, USA
    J Am Acad Dermatol 68:489-92. 2013
  8. pmc Extranodal Marginal Zone Lymphoma-like Presentations of Angioimmunoblastic T-Cell Lymphoma: A T-Cell Lymphoma Masquerading as a B-Cell Lymphoproliferative Disorder
    Benjamin Kaffenberger
    Division of Dermatology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH Division of Hematology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH and Division of Dermatopathology, Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH
    Am J Dermatopathol 37:604-13. 2015

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Novel biomarkers, dysregulated epigenetics, and therapy in cutaneous T-cell lymphoma
    Henry K Wong
    Division of Dermatology, Department of Internal Medicine, The Ohio State University, Gahanna, OH 43230, USA
    Discov Med 16:71-8. 2013
    ..This is supported by the efficacy of evolving therapeutic strategies that modulate gene regulation, such as HDAC inhibitors and methylation inhibitors in the treatment of this group of cancers. ..
  2. pmc Evolving insights in the pathogenesis and therapy of cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome)
    Henry K Wong
    Division of Dermatology, The Ohio State University, Columbus, OH 43221, USA
    Br J Haematol 155:150-66. 2011
    ..This review summarizes the clinical epidemiology, staging and natural history of MF and SS; discusses the immunopathogenesis of MF and the functional role of the malignant T-cells; and reviews the latest advances in MF and SS treatment...
  3. pmc Primary Cutaneous B-Cell Lymphoma: Management and Patterns of Recurrence at the Multimodality Cutaneous Lymphoma Clinic of The Ohio State University
    Brad Haverkos
    Comprehensive Cancer Center, Department of Pathology, Division of Hematology, Department of Medicine, Division of Dermatology, Department of Medicine, Center for Biostatistics, and Department of Radiation Oncology, The Ohio State University, Columbus, Ohio, USA Department of Dermatology, University of Arkansas for Medical Sciences, College of Medicine, Little Rock, Arkansas, USA
    Oncologist 20:1161-6. 2015
    ..Despite advances in the clinical and pathologic characterization of PCBCL, the significance of the current staging approach as a risk profiling tool and the effect of various treatments on outcome remain unclear...
  4. doi request reprint Promoter-Specific Hypomethylation Is Associated with Overexpression of PLS3, GATA6, and TWIST1 in the Sezary Syndrome
    Henry K Wong
    1 Division of Dermatology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA 2 The Comprehensive Cancer Center and The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, Ohio, USA
    J Invest Dermatol 135:2084-92. 2015
    ..The mechanisms of DNA hypomethylation in vivo and the functional role of PLS3, TWIST1, and GATA6 in SS are being investigated. ..
  5. pmc Impaired proteasome function activates GATA3 in T cells and upregulates CTLA-4: relevance for Sézary syndrome
    Heather M Gibson
    Division of Dermatology, The Ohio State University, Columbus, OH, USA
    J Invest Dermatol 133:249-57. 2013
    ..We also demonstrate the requirement of the GATA3/CTLA-4 regulatory pathway in fresh neoplastic CD4+ T cells. Targeting of this pathway may be beneficial in SS and other CTLA-4-overexpressing T-cell neoplasms...
  6. pmc Promoter methylation regulates SAMHD1 gene expression in human CD4+ T cells
    Suresh de Silva
    Center for Retrovirus Research, Department of Veterinary Biosciences, The OhioState University, Columbus, OH 43210, USA
    J Biol Chem 288:9284-92. 2013
    ..SAMHD1 expression was induced in CD4(+) T cell lines by blocking DNA methyltransferase activity, suggesting that promoter methylation is one of the key epigenetic mechanisms by which SAMHD1 expression is regulated...
  7. doi request reprint Remission of psoriasis after allogeneic, but not autologous, hematopoietic stem-cell transplantation
    Benjamin H Kaffenberger
    Dermatology, Ohio State University College of Medicine, Columbus, Ohio 43216, USA
    J Am Acad Dermatol 68:489-92. 2013
    ..Of these, 5 of 6 developed a recurrence of their psoriasis within 2 years. Based on a limited number of patients, psoriasis is likely to remit after allogeneic HSCT, but it is likely to recur after autologous HSCT...
  8. pmc Extranodal Marginal Zone Lymphoma-like Presentations of Angioimmunoblastic T-Cell Lymphoma: A T-Cell Lymphoma Masquerading as a B-Cell Lymphoproliferative Disorder
    Benjamin Kaffenberger
    Division of Dermatology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH Division of Hematology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH and Division of Dermatopathology, Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH
    Am J Dermatopathol 37:604-13. 2015
    ..Caution is urged to exclude the possibility of a systemic T-cell lymphoma such as AITL in cutaneous and lymph node B-cell proliferations. ..