Andrew P Steenhoff

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. ncbi request reprint Two cases of hypocalcemia secondary to vitamin D deficiency in an urban HIV-positive pediatric population
    David Chao
    AIDS 17:2401-3. 2003
  2. pmc An epidemiologic review of enteropathogens in Gaborone, Botswana: shifting patterns of resistance in an HIV endemic region
    Jack S Rowe
    Botswana UPenn Partnership, Gaborone, Botswana
    PLoS ONE 5:e10924. 2010
  3. pmc Neurocognitive impairment among HIV-positive individuals in Botswana: a pilot study
    Kathy Lawler
    Center for AIDS Research, University of Pennsylvania, Philadelphia, USA
    J Int AIDS Soc 13:15. 2010
  4. pmc Multiple oncogenic viruses identified in Ocular surface squamous neoplasia in HIV-1 patients
    Kenneth O Simbiri
    Department of Microbiology, and Abramson Comprehensive Cancer Center, Tumor Virology Program, University of Pennsylvania, 202A Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104 6076, USA
    Infect Agent Cancer 5:6. 2010
  5. ncbi request reprint Neuroborreliosis with progression from pseudotumor cerebri to aseptic meningitis
    Andrew P Steenhoff
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Pediatr Infect Dis J 25:91-2. 2006
  6. ncbi request reprint Emergence of vaccine-related pneumococcal serotypes as a cause of bacteremia
    Andrew P Steenhoff
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Clin Infect Dis 42:907-14. 2006
  7. ncbi request reprint Cutaneous Mycobacterium avium complex infection as a manifestation of the immune reconstitution syndrome in a human immunodeficiency virus-infected child
    Andrew P Steenhoff
    Division of Special Immunology, The Children s Hospital of Philadelphia, PA 19104, USA
    Pediatr Infect Dis J 26:755-7. 2007
  8. doi request reprint Invasive pneumococcal disease among human immunodeficiency virus-infected children, 1989-2006
    Andrew P Steenhoff
    Division of Special Immunology, Department of Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Pediatr Infect Dis J 27:886-91. 2008
  9. pmc Matrix Metalloproteinases in Tuberculosis-Immune Reconstitution Inflammatory Syndrome and Impaired Lung Function Among Advanced HIV/TB Co-infected Patients Initiating Antiretroviral Therapy
    Shruthi Ravimohan
    Department of Medicine, Division of Infectious Diseases, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Botswana UPenn Partnership, Gaborone, Botswana
    EBioMedicine 3:100-7. 2016
  10. doi request reprint Tenofovir-associated nephrotoxicity in two HIV-infected adolescent males
    Sarah M Wood
    Division of Special Immunology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    AIDS Patient Care STDS 23:1-4. 2009

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Two cases of hypocalcemia secondary to vitamin D deficiency in an urban HIV-positive pediatric population
    David Chao
    AIDS 17:2401-3. 2003
  2. pmc An epidemiologic review of enteropathogens in Gaborone, Botswana: shifting patterns of resistance in an HIV endemic region
    Jack S Rowe
    Botswana UPenn Partnership, Gaborone, Botswana
    PLoS ONE 5:e10924. 2010
    ..Secondary objectives included determining corresponding antimicrobial resistance patterns and the value of stool white and red blood cells for predicting bacterial and parasitic enteropathogens...
  3. pmc Neurocognitive impairment among HIV-positive individuals in Botswana: a pilot study
    Kathy Lawler
    Center for AIDS Research, University of Pennsylvania, Philadelphia, USA
    J Int AIDS Soc 13:15. 2010
    ....
  4. pmc Multiple oncogenic viruses identified in Ocular surface squamous neoplasia in HIV-1 patients
    Kenneth O Simbiri
    Department of Microbiology, and Abramson Comprehensive Cancer Center, Tumor Virology Program, University of Pennsylvania, 202A Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104 6076, USA
    Infect Agent Cancer 5:6. 2010
    ..Ocular surface squamous neoplasia (OSSN) is a rare cancer that has increased in incidence with the HIV pandemic in Africa. The underlying cause of this cancer in HIV-infected patients from Botswana is not well defined...
  5. ncbi request reprint Neuroborreliosis with progression from pseudotumor cerebri to aseptic meningitis
    Andrew P Steenhoff
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Pediatr Infect Dis J 25:91-2. 2006
    ..The case illustrates the importance of considering neuroborreliosis in the differential diagnosis of pseudotumor cerebri and describes the evolution of cerebrospinal fluid findings in this condition...
  6. ncbi request reprint Emergence of vaccine-related pneumococcal serotypes as a cause of bacteremia
    Andrew P Steenhoff
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Clin Infect Dis 42:907-14. 2006
    ..In the postlicensure period, the impact of non-PCV7 serotypes against pediatric pneumococcal bacteremia is unknown...
  7. ncbi request reprint Cutaneous Mycobacterium avium complex infection as a manifestation of the immune reconstitution syndrome in a human immunodeficiency virus-infected child
    Andrew P Steenhoff
    Division of Special Immunology, The Children s Hospital of Philadelphia, PA 19104, USA
    Pediatr Infect Dis J 26:755-7. 2007
    ..The case illustrates that cutaneous Mycobacterium avium complex may present as a manifestation of the immune reconstitution syndrome in human immunodeficiency virus-infected children...
  8. doi request reprint Invasive pneumococcal disease among human immunodeficiency virus-infected children, 1989-2006
    Andrew P Steenhoff
    Division of Special Immunology, Department of Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Pediatr Infect Dis J 27:886-91. 2008
    ..The heptavalent pneumococcal conjugate vaccine (PCV7) has decreased the incidence of pediatric invasive pneumococcal disease (IPD) in the United States. Few data exist on the changing IPD incidence in HIV-infected children...
  9. pmc Matrix Metalloproteinases in Tuberculosis-Immune Reconstitution Inflammatory Syndrome and Impaired Lung Function Among Advanced HIV/TB Co-infected Patients Initiating Antiretroviral Therapy
    Shruthi Ravimohan
    Department of Medicine, Division of Infectious Diseases, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Botswana UPenn Partnership, Gaborone, Botswana
    EBioMedicine 3:100-7. 2016
    ..Thus, reconstitution of immune function on ART could drive incident lung damage in HIV/TB...
  10. doi request reprint Tenofovir-associated nephrotoxicity in two HIV-infected adolescent males
    Sarah M Wood
    Division of Special Immunology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    AIDS Patient Care STDS 23:1-4. 2009
    ..We believe these cases highlight important and potentially irreversible side effects of this agent and emphasize the need for further studies of the renal safety of TDF in pediatric patients...
  11. pmc Chest Radiographic Findings and Outcomes of Pneumonia Among Children in Botswana
    Matthew S Kelly
    From the Botswana UPenn Partnership, Gaborone, Botswana Division of Global Health, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania Division of Pediatric Infectious Diseases, Duke University Medical Center, Durham, North Carolina Department of Radiology and Medical Imaging, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio Department of Epidemiology, Department of Immunology and Infectious Diseases, Harvard T H Chan School of Public Health, Boston, Massachusetts Division of Infectious Diseases, The Children s Hospital of Philadelphia Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Department of Pediatrics and Adolescent Health, Faculty of Medicine, University of Botswana Ministry of Health, Gaborone, Botswana and Division of Hospital Medicine and Division of Infectious Diseases, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio
    Pediatr Infect Dis J 35:257-62. 2016
    ..Few studies examined whether chest radiographic findings predict outcomes of children with clinically suspected pneumonia in these settings...
  12. pmc Association between efavirenz-based compared with nevirapine-based antiretroviral regimens and virological failure in HIV-infected children
    Elizabeth D Lowenthal
    Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA
    JAMA 309:1803-9. 2013
    ..Data on the comparative effectiveness of these medications in children are limited...
  13. doi request reprint Etiology of meningitis among patients admitted to a tertiary referral hospital in Botswana
    Paul C Mullan
    Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
    Pediatr Infect Dis J 30:620-2. 2011
    ..There were also 1018 cryptococcal and 44 tuberculous meningitis cases. Antimicrobial susceptibilities are described. Public health interventions could decrease the burden of meningitis in Botswana...
  14. pmc Incidence of and risk factors for community acquired pneumonia in US HIV-infected children, 2000-2005
    Andrew P Steenhoff
    Department of Pediatrics, Children s Hospital Philadelphia, Pennsylvania, USA
    AIDS 25:717-20. 2011
    ..98; confidence interval 1.05-15.13) was associated with CAP. Herd immunity through pneumococcal immunization may have diluted the effect of individual immunization in this cohort...
  15. ncbi request reprint Staphylococcus aureus skin and soft tissue infections at a tertiary hospital in Botswana
    Hong Truong
    Jefferson Medical College, Philadelphia, PA, USA
    S Afr Med J 101:413-6. 2011
    ..aureus isolates over time...
  16. ncbi request reprint Antibiotic use in pediatric patients admitted to a referral hospital in Botswana
    Brian T Fisher
    Division of Infectious Diseases and Departments of Pediatrics and Anesthesia and Critical Care, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Am J Trop Med Hyg 81:129-31. 2009
    ..The results showed that the duration of prescribed therapy can be excessive. Recommendations for potential interventions to reduce antibiotic overuse in this setting are necessary...
  17. ncbi request reprint Primary varicella and herpes zoster among HIV-infected children from 1989 to 2006
    Sarah M Wood
    Special Immunology Service, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Pediatrics 121:e150-6. 2008
    ..We hypothesized that the incidence of herpes zoster has decreased in this population as a result of highly active antiretroviral therapy and routine varicella zoster virus immunization...
  18. pmc Epidemiology of methicillin-resistant Staphylococcus aureus bacteremia in Gaborone, Botswana
    Sarah M Wood
    Children s Hospital of Philadelphia, PA 19104, USA
    Infect Control Hosp Epidemiol 30:782-5. 2009
    ..aureus (MRSA) bacteremia. MRSA isolates had higher proportions of resistance to commonly used antimicrobials than did methicillin-susceptible isolates, emphasizing the need to revise empiric prescribing practices in Botswana...
  19. doi request reprint The impact of AIDS diagnoses on long-term neurocognitive and psychiatric outcomes of surviving adolescents with perinatally acquired HIV
    Sarah M Wood
    Special Immunology Service, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    AIDS 23:1859-65. 2009
    ..To explore the association between previous severe HIV disease, defined as past Centers for Disease Control and Prevention class C diagnosis, and neurocognitive and psychiatric outcomes in long-term survivors of perinatally acquired HIV...
  20. pmc Effects of sex and alcohol use on antiretroviral therapy outcomes in Botswana: a cohort study
    Robert Gross
    Department of Medicine ID, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
    Addiction 112:73-81. 2017
    ..To determine alcohol use effect on HIV treatment success and whether alcohol use mediates the relation between male sex and treatment failure...
  21. ncbi request reprint Mycoplasma pneumoniae, splenic infarct, and transient antiphospholipid antibodies: a new association?
    Char M Witmer
    Division of Hematology, Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Pediatrics 119:e292-5. 2007
    ..We report 2 children with Mycoplasma pneumoniae pulmonary infection with splenic infarcts and transient antiphospholipid antibodies. This association has not been reported previously...
  22. pmc Vitamin D Status in Botswana Children Under 2 Years Old With and Without Active Tuberculosis
    Jonathan Ludmir
    Botswana UPenn Partnership, Gaborone, Botswana University of Maryland Medical Center, Baltimore, Maryland Department of Paediatrics and Adolescent Health, University of Botswana, Gaborone, Botswana Department of Public Health Medicine Unit, Faculty of Medicine, University of Botswana, Gaborone, Botswana Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Botswana Harvard Partnership, Gaborone, Botswana MRC Wits Developmental Pathways for Health Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa Internal Medicine Pediatrics, University of Miami Jackson Memorial Hospital, Miami, Florida Children s Hospital of Philadelphia, Philadelphia, Pennsylvania Department of Medicine Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
    Am J Trop Med Hyg 94:971-4. 2016
    ..There was no significant difference in vitamin D status between children under 2 years old with and without active TB. Lower vitamin D status did not appear to be a risk factor for TB in this small Gaborone cohort. ..
  23. pmc Risk Factors for Measles in HIV-infected Children and Adolescents in Botswana
    Kathleen E Wirth
    From the Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts Department of Paediatrics and Adolescent Health, University of Botswana, Gaborone, Botswana Department of Pediatrics, University of Washington, Seattle, Washington Botswana UPenn Partnership, Gaborone, Botswana Department of Pediatrics, McMaster University, Hamilton, Canada University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania Botswana Baylor Children s Clinical Centre of Excellence, Gaborone, Botswana Baylor College of Medicine International Pediatric AIDS Initiative at Texas Children s Hospital, Houston, Texas and Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania
    Pediatr Infect Dis J 34:1093-5. 2015
    ..1 years) were 4-fold more likely to acquire measles than those in the youngest quartile (<7.1 years). HIV-infected older children and adolescents may benefit from additional measles vaccination. ..
  24. pmc Immunological profiling of tuberculosis-associated immune reconstitution inflammatory syndrome and non-immune reconstitution inflammatory syndrome death in HIV-infected adults with pulmonary tuberculosis starting antiretroviral therapy: a prospective obse
    Shruthi Ravimohan
    Department of Medicine, Division of Infectious Diseases, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Botswana UPenn Partnership, Gaborone, Botswana Electronic address
    Lancet Infect Dis 15:429-38. 2015
    ..We aimed to assess whether patients who have these outcomes have distinct immunological profiles before and after ART initiation...
  25. pmc Pediatric Cerebral Palsy in Botswana: Etiology, Outcomes, and Comorbidities
    David R Bearden
    Division of Neurology, Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania Botswana UPenn Partnership, University of Pennsylvania, Philadelphia Department of Pediatrics, University of Botswana, Gaborone, Botswana Electronic address
    Pediatr Neurol 59:23-9. 2016
    ..Although cerebral palsy has been studied extensively in high-resource settings, there are few published studies on cerebral palsy etiology, outcomes and comorbidities in low-resource settings...
  26. doi request reprint Ocular surface squamous neoplasia among HIV-infected patients in Botswana
    Katherine T Steele
    Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Botswana University of Pennsylvania Partnership, Gaborone, Botswana
    S Afr Med J 105:379-83. 2015
    ..Ocular surface squamous neoplasia (OSSN) is a group of ocular tumours that has been rising in incidence among HIV-infected individuals in sub-Saharan Africa. Surgical excision is the mainstay of treatment for OSSN in this region...
  27. pmc Early antiretroviral therapy is protective against epilepsy in children with human immunodeficiency virus infection in botswana
    David Bearden
    Division of Neurology, The Children s Hospital of Philadelphia, Philadelphia, PA Botswana UPenn Partnership, Philadelphia, PA Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA Division of Infectious Disease, Children s Hospital of Philadelphia, Philadelphia, PA Division of Neurology, Hospital of the University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA Texas Children s Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, PA Department of Pediatrics, University of Botswana, Gaborone, Botswana Botswana Baylor Children s Clinical Centre of Excellence, Gaborone, Botswana and Division of Infectious Disease, Hospital of the University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA
    J Acquir Immune Defic Syndr 69:193-9. 2015
    ..Early treatment with combination antiretroviral therapy (cART) may reduce this risk by decreasing rates of central nervous system infections and HIV encephalopathy...
  28. pmc Vitamin D₃supplementation in Batswana children and adults with HIV: a pilot double blind randomized controlled trial
    Andrew P Steenhoff
    Botswana UPenn Partnership, Gaborone, Botswana Division of Infectious Diseases, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America Department of Pediatrics and Adolescent Health, School of Medicine, University of Botswana, Gaborone, Botswana
    PLoS ONE 10:e0117123. 2015
    ..Since vitamin D insufficiency is common worldwide in people with HIV, we explored safety and efficacy of high dose cholecalciferol (D₃) in Botswana, and evaluated potential modifiers of serum 25 hydroxy vitamin D change (Δ25D)...
  29. pmc Baseline predictors of efavirenz-containing antiretroviral regimen adverse experiences
    Paul D Sonenthal
    Botswana University of Pennsylvania Partnership, Gaborone, Botswana Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA Center for Pharmacoepidemiology Research and Training, University of Pennsylvania, Philadelphia, PA, USA
    Pharmacoepidemiol Drug Saf 23:773-7. 2014
    ..We aimed to identify modifiable, routinely available patient characteristics associated with adverse experiences potentially attributable to efavirenz-based regimens in patients in Botswana...
  30. pmc Early mortality and AIDS progression despite high initial antiretroviral therapy adherence and virologic suppression in Botswana
    Katherine T Steele
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 6:e20010. 2011
    ..We sought to determine the relationship between very early ART adherence and early adverse outcomes in HIV-infected adults in Botswana...
  31. doi request reprint Ancillary testing in children with rotavirus gastroenteritis
    Peter A Rowinsky
    Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA
    J Hosp Med 4:E36-40. 2009
    ..The primary objective was to describe the incidence of SBI in children with RGE. The secondary objective was to elucidate risk factors for prolonged length of stay (LOS) in the cohort...
  32. pmc Impact of Rotavirus Vaccination on Hospitalizations and Deaths From Childhood Gastroenteritis in Botswana
    Leslie A Enane
    Division of Infectious Diseases, Department of Pediatrics, Children s Hospital of Philadelphia, Pennsylvania Botswana UPenn Partnership, Gaborone, Botswana
    Clin Infect Dis 62:S168-74. 2016
    ..A monovalent human rotavirus vaccine (RV1) was introduced in Botswana in July 2012. We assessed the impact of RV1 vaccination on childhood gastroenteritis-related hospitalizations and deaths in 2013 and 2014...
  33. pmc Association of respiratory viruses with outcomes of severe childhood pneumonia in Botswana
    Matthew S Kelly
    Botswana UPenn Partnership, Gaborone, Botswana Global Health Center, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America Division of Pediatric Infectious Diseases, Duke University Medical Center, Durham, North Carolina, United States of America
    PLoS ONE 10:e0126593. 2015
    ..The highest incidence of childhood acute lower respiratory tract infection (ALRI) is in low- and middle-income countries. Few studies examined whether detection of respiratory viruses predicts ALRI outcomes in these settings...
  34. doi request reprint Impact of contextualized pediatric resuscitation training on pediatric healthcare providers in Botswana
    Shelton W Wright
    Children s Hospital of Philadelphia, 3400 Civic Center Blvd, Philadelphia, PA 19104, United States
    Resuscitation 88:57-62. 2015
    ..Worldwide, 6.6 million children die each year, partly due to a failure to recognize and treat acutely ill children. Programs that improve provider recognition and treatment initiation may improve child survival...
  35. pmc Training hospital providers in basic CPR skills in Botswana: acquisition, retention and impact of novel training techniques
    Peter A Meaney
    Department of Anesthesia and Critical Care, Children s Hospital of Philadelphia, Philadelphia, PA, United States
    Resuscitation 83:1484-90. 2012
    ..We hypothesized that both existing and novel CPR training programs significantly impact skills of hospital-based healthcare providers (HCP) in Botswana...