Kim Smith-Whitley

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. ncbi request reprint Knowledge of stroke risk, signs of stroke, and the need for stroke education among children with sickle cell disease and their caregivers
    Mira L Katz
    Department of Public Health, Temple University, Philadelphia, USA
    Ethn Health 7:115-23. 2002
  2. doi request reprint Indications and complications of transfusions in sickle cell disease
    Kim Smith-Whitley
    Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Pediatr Blood Cancer 59:358-64. 2012
  3. ncbi request reprint Epidemiology of human parvovirus B19 in children with sickle cell disease
    Kim Smith-Whitley
    Division of Hematology, The Children s Hospital of Philadelphia, 34th and Civic Center Blvd, Philadelphia, PA 19104, USA
    Blood 103:422-7. 2004
  4. pmc Non-invasive measurements of carboxyhemoglobin and methemoglobin in children with sickle cell disease
    Jason B Caboot
    Division of Pulmonary Medicine, Department of Pediatrics, University of Pennsylvania School of Medicine, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Pediatr Pulmonol 47:808-15. 2012
  5. pmc Upper airway genioglossal activity in children with sickle cell disease
    Jingtao Huang
    Sleep Center, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Sleep 34:773-8. 2011
  6. ncbi request reprint Transcranial Doppler ultrasonography in siblings with sickle cell disease
    Janet L Kwiatkowski
    Division of Hematology, The Children s Hospital of Philadelphia, Wood Building, 4th Floor, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Br J Haematol 121:932-7. 2003
  7. doi request reprint Epidemiology of bloodstream infections in children with sickle cell disease
    Angela M Ellison
    Division of Emergency Medicine, Department of Pediatrics, The Children s Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    Pediatr Infect Dis J 32:560-3. 2013
  8. doi request reprint High prevalence of red blood cell alloimmunization in sickle cell disease despite transfusion from Rh-matched minority donors
    Stella T Chou
    Division of Hematology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Blood 122:1062-71. 2013
  9. pmc Hemoglobin to Hematocrit Ratio: The Strongest Predictor of Femoral Head Osteonecrosis in Children With Sickle Cell Disease
    Douglas Worrall
    The Children s Hospital of Philadelphia, Philadelphia, PA
    J Pediatr Orthop 36:139-44. 2016
  10. doi request reprint Initial development of a questionnaire evaluating perceived benefits and barriers to pediatric clinical trials participation
    Lamia P Barakat
    The Children s Hospital of Philadelphia, USA
    Contemp Clin Trials 34:218-26. 2013

Research Grants

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Knowledge of stroke risk, signs of stroke, and the need for stroke education among children with sickle cell disease and their caregivers
    Mira L Katz
    Department of Public Health, Temple University, Philadelphia, USA
    Ethn Health 7:115-23. 2002
    ..This study assessed stroke knowledge and the need for stroke education among children with sickle cell disease (SCD) and their caregivers...
  2. doi request reprint Indications and complications of transfusions in sickle cell disease
    Kim Smith-Whitley
    Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Pediatr Blood Cancer 59:358-64. 2012
    ..In this report we review current indications for transfusions, transfusion complications, modifications of transfusion practices to mitigate risk, and potential considerations to improve transfusion outcomes...
  3. ncbi request reprint Epidemiology of human parvovirus B19 in children with sickle cell disease
    Kim Smith-Whitley
    Division of Hematology, The Children s Hospital of Philadelphia, 34th and Civic Center Blvd, Philadelphia, PA 19104, USA
    Blood 103:422-7. 2004
    ....
  4. pmc Non-invasive measurements of carboxyhemoglobin and methemoglobin in children with sickle cell disease
    Jason B Caboot
    Division of Pulmonary Medicine, Department of Pediatrics, University of Pennsylvania School of Medicine, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Pediatr Pulmonol 47:808-15. 2012
    ..Although the non-invasive technique slightly overestimated the invasive COHb measurements and slightly underestimated the invasive MetHb measurements, there was close agreement between the two methods...
  5. pmc Upper airway genioglossal activity in children with sickle cell disease
    Jingtao Huang
    Sleep Center, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Sleep 34:773-8. 2011
    ..However, not all subjects with SCD develop OSAS. We hypothesized that SCD patients with OSAS have a blunted neuromuscular response to subatmospheric pressure loads during sleep, making them more likely to develop upper airway collapse...
  6. ncbi request reprint Transcranial Doppler ultrasonography in siblings with sickle cell disease
    Janet L Kwiatkowski
    Division of Hematology, The Children s Hospital of Philadelphia, Wood Building, 4th Floor, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Br J Haematol 121:932-7. 2003
    ..Our results are consistent with a familial predisposition to cerebral vasculopathy in SCD...
  7. doi request reprint Epidemiology of bloodstream infections in children with sickle cell disease
    Angela M Ellison
    Division of Emergency Medicine, Department of Pediatrics, The Children s Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    Pediatr Infect Dis J 32:560-3. 2013
    ..Central venous access device associated infections are a new burden to efforts aimed at preventing bloodstream infections in this population. ..
  8. doi request reprint High prevalence of red blood cell alloimmunization in sickle cell disease despite transfusion from Rh-matched minority donors
    Stella T Chou
    Division of Hematology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Blood 122:1062-71. 2013
    ..Whether RH genotyping of patients and minority donors will reduce Rh alloimmunization in SCD needs to be examined. ..
  9. pmc Hemoglobin to Hematocrit Ratio: The Strongest Predictor of Femoral Head Osteonecrosis in Children With Sickle Cell Disease
    Douglas Worrall
    The Children s Hospital of Philadelphia, Philadelphia, PA
    J Pediatr Orthop 36:139-44. 2016
    ..Identifying risk factors linked to ON in SCD can facilitate earlier precollapse diagnosis and surgical treatment aimed at preservation of the native hip joint...
  10. doi request reprint Initial development of a questionnaire evaluating perceived benefits and barriers to pediatric clinical trials participation
    Lamia P Barakat
    The Children s Hospital of Philadelphia, USA
    Contemp Clin Trials 34:218-26. 2013
    ....
  11. pmc Transcranial Doppler ultrasonography and prophylactic transfusion program is effective in preventing overt stroke in children with sickle cell disease
    Henrietta Enninful-Eghan
    Division of Hematology, Children s Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Pediatr 157:479-84. 2010
    ..To assess the impact of our transcranial Doppler ultrasonography (TCD) program on the incidence of first stroke and the rate of transfusion for stroke prevention in children with sickle cell disease...
  12. doi request reprint Pneumococcal bacteremia in a vaccinated pediatric sickle cell disease population
    Angela M Ellison
    Division of Emergency Medicine, The Children s Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    Pediatr Infect Dis J 31:534-6. 2012
    ..Despite established prophylactic strategies, pneumococcal bacteremia continues to occur in patients with sickle cell disease...
  13. pmc Mistrust of Pediatric Sickle Cell Disease Clinical Trials Research
    Evelyn M Stevens
    The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania Electronic address
    Am J Prev Med 51:S78-86. 2016
    ....
  14. ncbi request reprint Is treatment adherence associated with better quality of life in children with sickle cell disease?
    Lamia P Barakat
    Department of Psychology, Drexel University, Philadelphia, PA 19104, USA
    Qual Life Res 14:407-14. 2005
    ..Further research to investigate the role of sickle cell disease complications, as well as psychosocial factors, in determining both treatment adherence and QOL is suggested...
  15. ncbi request reprint Positive blood cultures in sickle cell disease: time to positivity and clinical outcome
    Cynthia F Norris
    Division of Hematology, Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, USA
    J Pediatr Hematol Oncol 25:390-5. 2003
    ....
  16. doi request reprint Psychiatric diagnosis in adolescents with sickle cell disease: a preliminary report
    Tami D Benton
    Department of Psychiatry, University of Pennsylvania School of Medicine The Children s Hospital of Philadelphia, The Behavioral Health Center, Suite 400, 3440 Market Street, Philadelphia, PA 19104, USA
    Curr Psychiatry Rep 13:111-5. 2011
    ..Awareness of risks for psychiatric disorders in SCD could lead to increased identification and interventions that may improve medical and psychiatric outcomes...
  17. ncbi request reprint Parent factors and adolescent sickle cell disease: associations with patterns of health service use
    Deirdre E Logan
    Department of PsychologyThe Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Pediatr Psychol 27:475-84. 2002
    ....
  18. doi request reprint Association of hospital and provider types on sickle cell disease outcomes
    Sophia Jan
    MSHP, CHOP PolicyLab, 3535 Market St, 15th Floor, Philadelphia, PA 19104
    Pediatrics 132:854-61. 2013
    ..We determined the effect of hospital type and provider specialty on outcomes of hospitalized A/YA with SCD and acute chest syndrome (ACS)...
  19. doi request reprint Magnetic resonance imaging in children with sickle cell disease--detecting alterations in the apparent diffusion coefficient in hips with avascular necrosis
    John D MacKenzie
    Department of Pediatric Radiology, Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Pediatr Radiol 42:706-13. 2012
    ..Avascular necrosis (AVN) is a common morbidity in children with sickle cell disease (SCD) that leads to pain and joint immobility. However, the diagnosis is often uncertain or delayed...
  20. pmc Definitions of the phenotypic manifestations of sickle cell disease
    Samir K Ballas
    Department of Medicine, Cardeza Foundation for Hematologic Research, Jefferson Medical College, Thomas Jefferson University, 1015 Walnut Street, Philadelphia, PA 19107, USA
    Am J Hematol 85:6-13. 2010
    ....
  21. pmc Periodic limb movements and disrupted sleep in children with sickle cell disease
    Valerie E Rogers
    University of Pennsylvania, Philadelphia, PA, USA
    Sleep 34:899-908. 2011
    ..To describe the rate, distribution and correlates of periodic limb movements in sleep (PLMS) in children with sickle cell disease (SCD)...
  22. pmc Silent infarcts in young children with sickle cell disease
    Janet L Kwiatkowski
    Division of Hematology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Br J Haematol 146:300-5. 2009
    ..The prevalence of silent infarcts in young children with SCD-SS is similar to that of older children and anaemia and severe vasculopathy may be risk factors...
  23. ncbi request reprint Anxiety and depression in children and adolescents with sickle cell disease
    Tami D Benton
    Department of Child and Adolescent Psychiatry, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Curr Psychiatry Rep 9:114-21. 2007
    ..This article reviews the evidence describing our knowledge of anxiety and depression in children and adolescents with SCD, its clinical impact, and effectiveness of interventions...
  24. pmc Headache in children with sickle cell disease: prevalence and associated factors
    Alison E Niebanck
    Duke University School of Medicine, USA
    J Pediatr 151:67-72, 72.e1. 2007
    ..To compare the prevalence of frequent headache in children with sickle cell disease (SCD) to that of black control subjects and to assess factors associated with headache in SCD...
  25. ncbi request reprint Streptococcus pneumoniae sepsis and meningitis during the penicillin prophylaxis era in children with sickle cell disease
    Jeffrey Hord
    Children s Hospital Medical Center of Akron, Aron, Ohio 44308, USA
    J Pediatr Hematol Oncol 24:470-2. 2002
    ..The administration of 7-valent Prevnar (Wyeth Lederle Vaccines, Philadelphia, PA, U.S.A.) to children younger than 24 months old with SCD should be beneficial, based on the serotype data...
  26. ncbi request reprint Risk of recurrent stroke in children with sickle cell disease receiving blood transfusion therapy for at least five years after initial stroke
    Douglas J Scothorn
    University of Texas Southwestern Medical Center, Dallas, TX, USA
    J Pediatr 140:348-54. 2002
    ....
  27. ncbi request reprint Predictors of fetal hemoglobin response in children with sickle cell anemia receiving hydroxyurea therapy
    Russell E Ware
    Duke University Medical Center, Durham, NC 27710, USA
    Blood 99:10-4. 2002
    ..The HbF response to hydroxyurea is variable and complex, however, and even children with low baseline %HbF values can develop substantial increases in %HbF at MTD...
  28. ncbi request reprint Morbidity and mortality in chronically transfused subjects with thalassemia and sickle cell disease: A report from the multi-center study of iron overload
    Ellen B Fung
    Department of Hematology, Children s Hospital and Research Center, Oakland, California, USA
    Am J Hematol 82:255-65. 2007
    ..Long term follow-up of this unique cohort of subjects will be helpful in further defining the relationship of chronic, heavy iron overload to morbidity and mortality...
  29. ncbi request reprint Effect of hydroxyurea on growth in children with sickle cell anemia: results of the HUG-KIDS Study
    Winfred C Wang
    Hematology Division, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
    J Pediatr 140:225-9. 2002
    ..We report the growth characteristics of patients in the Phase I-II pediatric hydroxyurea trial (HUG-KIDS) before and during treatment at the maximum tolerated dose for one year...

Research Grants1

  1. PULMONARY COMPLICATIONS IN PEDIATRIC SICKLE CELL DISEASE
    Kim Smith Whitley; Fiscal Year: 2002
    ....