Stan Stanislaw Krajewski

Summary

Affiliation: The Burnham Institute
Country: USA

Publications

  1. pmc Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma
    Frederic Luciano
    Burnham Institute for Medical Research, 10901 Torrey Pines Road, La Jolla, CA 92037, USA
    Blood 109:3849-55. 2007
  2. pmc Full length Bid is sufficient to induce apoptosis of cultured rat hippocampal neurons
    Hans Georg König
    Department of Physiology and RCSI Neuroscience Research Centre, Royal College of Surgeons in Ireland, Dublin 2, Ireland
    BMC Cell Biol 8:7. 2007
  3. doi request reprint "Rainbow" western blotting
    Stan Krajewski
    Burnham Institute for Medical Research, 10901 N Torrey Pines Rd, La Jolla, CA, 92037, USA
    Methods Mol Biol 536:463-72. 2009
  4. doi request reprint Multiple antigen detection (MAD) western blotting
    Stan Krajewski
    Burnham Institute for Medical Research, 10901 N Torrey Pines Rd, La Jolla, CA, 92037, USA
    Methods Mol Biol 536:473-81. 2009
  5. ncbi request reprint Calpain and mitochondria in ischemia/reperfusion injury
    Min Chen
    Scripps Research Institute and The Burnham Institute, La Jolla, California 92037, USA
    J Biol Chem 277:29181-6. 2002
  6. ncbi request reprint Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation
    Maryla Krajewska
    The Burnham Institute, La Jolla, CA 92037, USA
    Exp Neurol 189:261-79. 2004
  7. ncbi request reprint Analysis of apoptosis protein expression in early-stage colorectal cancer suggests opportunities for new prognostic biomarkers
    Maryla Krajewska
    The Burnham Institute, Department of Family Preventive Medicine, University of California San Diego, La Jolla, California, USA
    Clin Cancer Res 11:5451-61. 2005
  8. pmc Bcl-B expression in human epithelial and nonepithelial malignancies
    Maryla Krajewska
    Burnham Institute for Medical Research, La Jolla, California 92037, USA
    Clin Cancer Res 14:3011-21. 2008
  9. pmc Image analysis algorithms for immunohistochemical assessment of cell death events and fibrosis in tissue sections
    Maryla Krajewska
    Burnham Institute for Medical Research, La Jolla, California 92037, USA
    J Histochem Cytochem 57:649-63. 2009

Research Grants

  1. Caspases, Calpains and Neuronal Cell death
    Stan Krajewski; Fiscal Year: 2006

Collaborators

  • J C Reed
  • Xiao Kun Zhang
  • Roberta A Gottlieb
  • Aaron D Schimmer
  • Maryla Krajewska
  • Frederic Luciano
  • Allen H Olson
  • Xianshu Huang
  • Dayong Zhai
  • Alan Lichtenstein
  • Hans Georg König
  • Hoguen Kim
  • Min Chen
  • Barry Iacopetta
  • Layton H Smith
  • Marc L Hyer
  • Juan Rong
  • Steven P Linke
  • Nikolajs Zeps
  • Jane N Winter
  • Dan Mercola
  • Cheryl H Baker
  • Shinichi Kitada
  • Jacek Jassem
  • Ming Tsao
  • Anne Sawyers
  • Michael Cuddy
  • Michael J Duffy
  • Andrzej Badzio
  • Eunah Shin
  • Michael Andreeff
  • Susan Kennedy
  • Ivo Meinhold-Heerlein
  • Daina Variakojis
  • Ewan Brown
  • Arnold C Satterthwait
  • Markus Rehm
  • Paulina Ortiz-Rubio
  • Jean Marie Bruey
  • Jochen H M Prehn
  • Benjamin Faustin
  • Daniel Gudorf
  • Atan Gross
  • Siva Kumar Kolluri
  • Beatrice Bailly-Maitre
  • Manus W Ward
  • Zhe Piao
  • Michelle Tsukamoto
  • Koichi Suzuki
  • Shu Ichi Matsuzawa
  • Ronald G Thomas
  • Nuria Assa-Munt
  • Kate Welsh
  • Haeyoun Kang
  • Chul Kim
  • Manuel Perucho
  • Henning R Stennicke
  • Jowita Mikolajczyk
  • Guy S Salvesen
  • Juergen Mai
  • Mikihiko Naito
  • Thomas Wiesenthal
  • Robert E Rosenthal
  • Gary Fiskum
  • Dong Jun Won

Detail Information

Publications9

  1. pmc Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma
    Frederic Luciano
    Burnham Institute for Medical Research, 10901 Torrey Pines Road, La Jolla, CA 92037, USA
    Blood 109:3849-55. 2007
    ..Because Bcl-B is abundantly expressed in plasma cells and some myelomas, these findings raise the possibility of exploiting the Nur77/Bcl-B mechanism for apoptosis for eradication of autoimmune plasma cells or myeloma...
  2. pmc Full length Bid is sufficient to induce apoptosis of cultured rat hippocampal neurons
    Hans Georg König
    Department of Physiology and RCSI Neuroscience Research Centre, Royal College of Surgeons in Ireland, Dublin 2, Ireland
    BMC Cell Biol 8:7. 2007
    ..We induced a delayed excitotoxic cell death in cultured rat hippocampal neurons by a 5-min exposure to the glutamate receptor agonist N-methyl-D-aspartate (NMDA; 300 microM)...
  3. doi request reprint "Rainbow" western blotting
    Stan Krajewski
    Burnham Institute for Medical Research, 10901 N Torrey Pines Rd, La Jolla, CA, 92037, USA
    Methods Mol Biol 536:463-72. 2009
    ..This technique could be particularly valuable for analysis of comigrating proteins, isoforms, and/or facilitating studies on phosphorylation, acetylation, and oligomerization of proteins tagged by the same epitope...
  4. doi request reprint Multiple antigen detection (MAD) western blotting
    Stan Krajewski
    Burnham Institute for Medical Research, 10901 N Torrey Pines Rd, La Jolla, CA, 92037, USA
    Methods Mol Biol 536:473-81. 2009
    ..This technique could be particularly valuable for analyzing cellular populations that are difficult to isolate in large numbers or clinical specimens where the amount of protein samples is limited or available on a one-time basis...
  5. ncbi request reprint Calpain and mitochondria in ischemia/reperfusion injury
    Min Chen
    Scripps Research Institute and The Burnham Institute, La Jolla, California 92037, USA
    J Biol Chem 277:29181-6. 2002
    ..Ischemia/reperfusion initiates a cell death pathway that is independent of caspases but requires calpain and mitochondrial dysfunction...
  6. ncbi request reprint Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation
    Maryla Krajewska
    The Burnham Institute, La Jolla, CA 92037, USA
    Exp Neurol 189:261-79. 2004
    ....
  7. ncbi request reprint Analysis of apoptosis protein expression in early-stage colorectal cancer suggests opportunities for new prognostic biomarkers
    Maryla Krajewska
    The Burnham Institute, Department of Family Preventive Medicine, University of California San Diego, La Jolla, California, USA
    Clin Cancer Res 11:5451-61. 2005
    ..We tested the hypothesis that differences in expression of apoptosis-regulating proteins account for differences in clinical outcome among patients with early-stage colorectal cancer...
  8. pmc Bcl-B expression in human epithelial and nonepithelial malignancies
    Maryla Krajewska
    Burnham Institute for Medical Research, La Jolla, California 92037, USA
    Clin Cancer Res 14:3011-21. 2008
    ..Bcl-B is an antiapoptotic Bcl-2 family member, which is known to change its phenotype upon binding to Nur77/TR3. The expression pattern of this protein in human malignancies has not been reported...
  9. pmc Image analysis algorithms for immunohistochemical assessment of cell death events and fibrosis in tissue sections
    Maryla Krajewska
    Burnham Institute for Medical Research, La Jolla, California 92037, USA
    J Histochem Cytochem 57:649-63. 2009
    ..Examples are provided of digital image analysis performed in automated or semiautomated fashion for successful quantification of molecular events associated with cell death in tissue sections...

Research Grants1

  1. Caspases, Calpains and Neuronal Cell death
    Stan Krajewski; Fiscal Year: 2006
    ..These animals and cells derived from them will then be used for determining the importance of these proteases for neuronal cell death induced by cerebral ischemia and in certain neurodegenerative diseases. ..