Andrea Kelly

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. doi request reprint Trabecular and cortical bone deficits are present in children and adolescents with cystic fibrosis
    Andrea Kelly
    Division of Endocrinology and Diabetes, The Children s Hospital of Philadelphia, 3535 Market St, Philadelphia, PA 19104, USA Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Electronic address
    Bone 90:7-14. 2016
  2. doi request reprint Metabolic bone disease screening practices among U.S. neonatologists
    Andrea Kelly
    The Children s Hospital of Philadelphia, Philadelphia, PA, USA Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA, USA
    Clin Pediatr (Phila) 53:1077-83. 2014
  3. doi request reprint Update on cystic fibrosis-related diabetes
    Andrea Kelly
    Division of Endocrinology and Diabetes, Children s Hospital of Philadelphia, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA 19104, USA
    J Cyst Fibros 12:318-31. 2013
  4. ncbi request reprint Glutaminolysis and insulin secretion: from bedside to bench and back
    Andrea Kelly
    Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Diabetes 51:S421-6. 2002
  5. doi request reprint A cross-sectional study of vitamin D and insulin resistance in children
    Andrea Kelly
    Division of Endocrinology Diabetes, 1130 Northwest Tower, The Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Arch Dis Child 96:447-52. 2011
  6. pmc Catecholamines, adiponectin, and insulin resistance as measured by HOMA in children with obstructive sleep apnea
    Andrea Kelly
    Division Endocrinology Diabetes, The Children s Hospital of Philadelphia, Philadelphia, PA, 19104, USA
    Sleep 33:1185-91. 2010
  7. pmc Deficits in bone mineral content in children and adolescents with cystic fibrosis are related to height deficits
    Andrea Kelly
    Division of Endocrinology Diabetes, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Clin Densitom 11:581-9. 2008
  8. doi request reprint Poor specificity of low growth hormone and cortisol levels during fasting hypoglycemia for the diagnoses of growth hormone deficiency and adrenal insufficiency
    Andrea Kelly
    Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Division of Endocrinology Diabetes, 8416 Main Building, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Pediatrics 122:e522-8. 2008
  9. ncbi request reprint Protein-sensitive hypoglycemia without leucine sensitivity in hyperinsulinism caused by K(ATP) channel mutations
    Shannon H Fourtner
    Division of Endocrinology Diabetes, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    J Pediatr 149:47-52. 2006
  10. doi request reprint Nocturnal saturation and glucose tolerance in children with cystic fibrosis
    Dharmeshkumar Suratwala
    Children s Hospital of Philadelphia, Pulmonary Division, 9NW50, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Thorax 66:574-8. 2011

Collaborators

Detail Information

Publications30

  1. doi request reprint Trabecular and cortical bone deficits are present in children and adolescents with cystic fibrosis
    Andrea Kelly
    Division of Endocrinology and Diabetes, The Children s Hospital of Philadelphia, 3535 Market St, Philadelphia, PA 19104, USA Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Electronic address
    Bone 90:7-14. 2016
    ..The occurrence of these differences in CF youth highlights the importance of instituting measures to optimize peak bone mass early in the course of CF. ..
  2. doi request reprint Metabolic bone disease screening practices among U.S. neonatologists
    Andrea Kelly
    The Children s Hospital of Philadelphia, Philadelphia, PA, USA Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA, USA
    Clin Pediatr (Phila) 53:1077-83. 2014
    ..Our survey confirms widespread awareness of MBD but highlights lack of consensus regarding definition, screening, and treatment. Further research is needed to develop and optimize strategies to prevent, recognize, and manage MBD...
  3. doi request reprint Update on cystic fibrosis-related diabetes
    Andrea Kelly
    Division of Endocrinology and Diabetes, Children s Hospital of Philadelphia, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA 19104, USA
    J Cyst Fibros 12:318-31. 2013
    ....
  4. ncbi request reprint Glutaminolysis and insulin secretion: from bedside to bench and back
    Andrea Kelly
    Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Diabetes 51:S421-6. 2002
    ..These findings provide a foundation for defining pathways of basal secretion and AASIS, augmenting our understanding of beta-cell function...
  5. doi request reprint A cross-sectional study of vitamin D and insulin resistance in children
    Andrea Kelly
    Division of Endocrinology Diabetes, 1130 Northwest Tower, The Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Arch Dis Child 96:447-52. 2011
    ..PATIENTS/SETTING/DESIGN: Cross-sectional study of 85 children aged 4-18 years recruited from the local Philadelphia community and Sleep Center...
  6. pmc Catecholamines, adiponectin, and insulin resistance as measured by HOMA in children with obstructive sleep apnea
    Andrea Kelly
    Division Endocrinology Diabetes, The Children s Hospital of Philadelphia, Philadelphia, PA, 19104, USA
    Sleep 33:1185-91. 2010
    ..We hypothesized that OSA is associated with worse insulin resistance and lower adiponectin after adjustment for obesity and puberty and that catecholamines might mediate these changes...
  7. pmc Deficits in bone mineral content in children and adolescents with cystic fibrosis are related to height deficits
    Andrea Kelly
    Division of Endocrinology Diabetes, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Clin Densitom 11:581-9. 2008
    ..BMC deficits are related to altered body size, reduced LBM, and pulmonary function in children with CF. Interventions targeting improved growth, muscle mass, and pulmonary function may benefit bone health in CF...
  8. doi request reprint Poor specificity of low growth hormone and cortisol levels during fasting hypoglycemia for the diagnoses of growth hormone deficiency and adrenal insufficiency
    Andrea Kelly
    Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Division of Endocrinology Diabetes, 8416 Main Building, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Pediatrics 122:e522-8. 2008
    ....
  9. ncbi request reprint Protein-sensitive hypoglycemia without leucine sensitivity in hyperinsulinism caused by K(ATP) channel mutations
    Shannon H Fourtner
    Division of Endocrinology Diabetes, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    J Pediatr 149:47-52. 2006
    ....
  10. doi request reprint Nocturnal saturation and glucose tolerance in children with cystic fibrosis
    Dharmeshkumar Suratwala
    Children s Hospital of Philadelphia, Pulmonary Division, 9NW50, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Thorax 66:574-8. 2011
    ....
  11. pmc Rare EN1 Variants and Pediatric Bone Mass
    Jonathan A Mitchell
    Division of Gastroenterology, Hepatology, and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    J Bone Miner Res 31:1513-7. 2016
    ..The sex differences observed need to be independently replicated. © 2016 American Society for Bone and Mineral Research. ..
  12. pmc Physical Activity Benefits the Skeleton of Children Genetically Predisposed to Lower Bone Density in Adulthood
    Jonathan A Mitchell
    Division of Gastroenterology, Hepatology, and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    J Bone Miner Res 31:1504-12. 2016
    ..Independent replication of our exploratory individual variant findings is warranted. © 2016 American Society for Bone and Mineral Research. ..
  13. pmc Genetic Risk Scores Implicated in Adult Bone Fragility Associate With Pediatric Bone Density
    Jonathan A Mitchell
    Division of Gastroenterology, Hepatology and Nutrition, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    J Bone Miner Res 31:789-95. 2016
    ..In conclusion, adult identified BMD loci associated with BMD and BMC in the pediatric setting, especially in females and in loci involved in fracture risk and WNT signaling...
  14. pmc Polysomnographic values in children undergoing puberty: pediatric vs. adult respiratory rules in adolescents
    Ignacio E Tapia
    Sleep Center, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 USA
    Sleep 31:1737-44. 2008
    ....
  15. pmc Relative Skeletal Maturation and Population Ancestry in Nonobese Children and Adolescents
    Shana E McCormack
    Division of Endocrinology and Diabetes, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    J Bone Miner Res . 2016
    ..Further research into the mechanisms underlying this observation may provide insights into the regulation of skeletal maturation. © 2016 American Society for Bone and Mineral Research...
  16. ncbi request reprint Effects of a GTP-insensitive mutation of glutamate dehydrogenase on insulin secretion in transgenic mice
    Changhong Li
    Division of Endocrinology, The Children s Hospital of Philadelphia and Diabetes Center, Philadelphia, Pennsylvania 19104, USA
    J Biol Chem 281:15064-72. 2006
    ..This study suggests that GDH functions predominantly in the direction of glutamate oxidation rather than glutamate synthesis in mouse islets and that this flux is tightly controlled by glucose...
  17. pmc Height adjustment in assessing dual energy x-ray absorptiometry measurements of bone mass and density in children
    Babette S Zemel
    The Children s Hospital of Philadelphia, 3535 Market Street, Room 1560, Philadelphia, Pennsylvania 19104, USA
    J Clin Endocrinol Metab 95:1265-73. 2010
    ..No consensus exists on how to adjust BMC or BMD (BMC/BMD) measurements for short or tall stature...
  18. pmc Genetics of Bone Mass in Childhood and Adolescence: Effects of Sex and Maturation Interactions
    Jonathan A Mitchell
    Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    J Bone Miner Res 30:1676-83. 2015
    ..However, the direction and magnitude of associations for a large number of SNPs only became evident when accounting for sex and maturation...
  19. pmc Age-based reference ranges for annual height velocity in US children
    Andrea Kelly
    Department of Pediatrics A K, B S Z, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104 Eunice Kennedy Shriver National Institute of Child Health and Human Development K K W, Bethesda, Maryland 20892 Department of Pediatrics H K, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 Department of Pediatrics S E O, Columbia University Medical Center, New York, New York 10032 Department of Medicine J L, Creighton University, Omaha, Nebraska 68102 and Departments of Orthopaedic Surgery and Radiology V G, Children s Hospital Los Angeles, Los Angeles, California 90027
    J Clin Endocrinol Metab 99:2104-12. 2014
    ..We present empirically acquired, age-specific reference ranges for HV from a contemporary sample of US youth...
  20. ncbi request reprint Central nervous system hyperexcitability associated with glutamate dehydrogenase gain of function mutations
    David M Raizen
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, USA
    J Pediatr 146:388-94. 2005
    ..To describe seizure phenotypes associated with the hyperinsulinism/hyperammonemia syndrome (HI/HA), which is caused by gain of function mutations in the enzyme glutamate dehydrogenase (GDH)...
  21. pmc Hypertrophic cardiomyopathy in neonates with congenital hyperinsulinism
    Tingting Huang
    Division of Endocrinology and Diabetes, Department of Pediatrics, The Children s Hospital of Philadelphia, The University of Pennsylvania School of Medicine, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
    Arch Dis Child Fetal Neonatal Ed 98:F351-4. 2013
    ..HCM has been reported in a few neonates with hyperinsulinism, but its extent and risk factors for its development have not been evaluated...
  22. pmc Puberty and upper airway dynamics during sleep
    Preetam Bandla
    Sleep Center, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, PA 19104, USA
    Sleep 31:534-41. 2008
    ..We hypothesized that the upper airway response to subatmospheric pressure loading decreased with increasing pubertal Tanner stage in males but remained stable during puberty in females...
  23. pmc Case files of the Medical Toxicology Fellowship Training Program at the Children's Hospital of Philadelphia: a pediatric exploratory sulfonylurea ingestion
    Diane P Calello
    Division of Emergency Medicine, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    J Med Toxicol 2:19-24. 2006
  24. ncbi request reprint Genotype-phenotype correlations in children with congenital hyperinsulinism due to recessive mutations of the adenosine triphosphate-sensitive potassium channel genes
    Maria J Henwood
    Division of Endocrinology Diabetes, The Children s Hospital of Philadelphia, Pennsylvania 19104, USA
    J Clin Endocrinol Metab 90:789-94. 2005
    ..These results indicate that some K(ATP) mutations can yield partially functioning channels, including cases of hyperinsulinism that are fully responsive to diazoxide therapy...
  25. pmc Elevation of 1-hour plasma glucose during oral glucose tolerance testing is associated with worse pulmonary function in cystic fibrosis
    Jill Brodsky
    Division of Pediatric Endocrinology and Diabetes, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Diabetes Care 34:292-5. 2011
    ..We hypothesized PG elevations during OGTT resolving by 2 h, not meeting CFRD criteria, influence pulmonary function in CF. Thus we investigated the frequency of elevated 1-h OGTT PG (PG1) and its relationship with pulmonary function...
  26. ncbi request reprint Size of testes, ovaries, uterus and breast buds by ultrasound in healthy full-term neonates ages 0-3 days
    Summer L Kaplan
    Department of Radiology, The Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA, 19104, USA
    Pediatr Radiol 46:1837-1847. 2016
    ..Clinical and research evaluation of hormonal and genitourinary disorders would benefit from reference size standards...
  27. doi request reprint Biomarkers of Insulin for the Diagnosis of Hyperinsulinemic Hypoglycemia in Infants and Children
    Christine Ferrara
    Division of Endocrinology and Diabetes, Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, PA
    J Pediatr 168:212-9. 2016
    ..To evaluate thresholds of various biomarkers for defining excess insulin activity to recognize congenital hyperinsulinism...
  28. pmc Sex differences in the associations of visceral adiposity, homeostatic model assessment of insulin resistance, and body mass index with lipoprotein subclass analysis in obese adolescents
    Jacquelyn A Hatch-Stein
    Division of Endocrinology and Diabetes, The Children s Hospital of Philadelphia, Philadelphia, PA, USA Electronic address
    J Clin Lipidol 10:757-66. 2016
    ..The relationship of lipoprotein particle subclasses to visceral adipose tissue area (VAT-area) in obese children has not been examined previously...
  29. doi request reprint Elevation of one hour plasma glucose during oral glucose tolerance testing
    Saba Sheikh
    Division of Pulmonary Medicine and Cystic Fibrosis Center, The Children s Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
    Pediatr Pulmonol 50:963-9. 2015
    ..Thus, we examined associations of PG1 with percent-predicted forced expiratory volume in 1 sec (FEV1 % predicted), CF exacerbations, and CF related diabetes (CFRD) development...
  30. pmc Body mass index (BMI) trajectories in infancy differ by population ancestry and may presage disparities in early childhood obesity
    Sani M Roy
    Division of Endocrinology and Diabetes S M R, A K, S F A G, S E M, Division of Human Genetics A C, H H, S F A G, Center for Applied Genomics F M, R C, H H, S F A G, Division of Gastroenterology, Hepatology, and Nutrition B S Z, The Children s Hospital of Philadelphia, and Departments of Biostatistics and Epidemiology R X, J A M and Pediatrics A K, H H, S F A G, B S Z, S E M, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104
    J Clin Endocrinol Metab 100:1551-60. 2015
    ..After age 2 years, high body mass index (BMI) is related to adverse cardiometabolic outcomes. Before age 2 years, the utility of BMI as a metric of excess adiposity is unknown...