Ashraful Hoque

Summary

Affiliation: The University of Texas
Country: USA

Publications

  1. pmc Effect of finasteride on serum androstenedione and risk of prostate cancer within the prostate cancer prevention trial: differential effect on high- and low-grade disease
    Ashraful Hoque
    Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX Electronic address
    Urology 85:616-20. 2015
  2. pmc Serum estrogen levels and prostate cancer risk in the prostate cancer prevention trial: a nested case-control study
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA
    Cancer Causes Control 22:1121-31. 2011
  3. doi request reprint Statin induces apoptosis and cell growth arrest in prostate cancer cells
    Ashraful Hoque
    Department of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer Epidemiol Biomarkers Prev 17:88-94. 2008
  4. pmc Prognostic significance of differentially expressed miRNAs in esophageal cancer
    Yuxin Hu
    Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX77030, USA
    Int J Cancer 128:132-43. 2011
  5. pmc Repeat polymorphisms in estrogen metabolism genes and prostate cancer risk: results from the Prostate Cancer Prevention Trial
    Li Tang
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Carcinogenesis 32:1500-6. 2011
  6. ncbi request reprint Tumor-suppressive effect of retinoid receptor-induced gene-1 (RRIG1) in esophageal cancer
    Jie Huang
    Department of Clinical Cancer Prevention, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer Res 67:1589-93. 2007
  7. pmc Antitumor effect of retinoic acid receptor-beta2 associated with suppression of cyclooxygenase-2
    Shumei Song
    Department of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer Prev Res (Phila) 2:274-80. 2009
  8. ncbi request reprint Increased retinoic acid receptor-beta4 correlates in vivo with reduced retinoic acid receptor-beta2 in esophageal squamous cell carcinoma
    Xiao Chun Xu
    Department of Clinical Cancer Prevention, Unit 1360, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer Epidemiol Biomarkers Prev 14:826-9. 2005
  9. pmc Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial
    Bora Gurel
    Authors Affiliations Departments of Pathology and Immunology The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins School of Medicine Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore Division of Cancer Prevention, Department of Health and Human Services, National Cancer Institute, NIH, Bethesda, Maryland University of Colorado School of Medicine, Aurora, Colorado Department of Urology, University of Texas Health Sciences Center San Antonio, San Antonio Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas SWOG Statistical Center Cancer Prevention Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington Moores Cancer Center, University of California San Diego, La Jolla, California and Division of Public Health Sciences and The Alvin J Siteman Cancer Center, Department of Surgery, Washington University School of Medicine, St Louis, Missouri
    Cancer Epidemiol Biomarkers Prev 23:847-56. 2014
  10. ncbi request reprint Loss of the expression of the tumor suppressor gene ARHI is associated with progression of breast cancer
    Lin Wang
    Departments of Experimental Therapeutics L W, R Z L, J Y, Z L, A N, R C B, Y Y, Clinical Cancer Prevention A H, S M L, and Pathology J L, A A S, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030
    Clin Cancer Res 9:3660-6. 2003

Research Grants

Detail Information

Publications23

  1. pmc Effect of finasteride on serum androstenedione and risk of prostate cancer within the prostate cancer prevention trial: differential effect on high- and low-grade disease
    Ashraful Hoque
    Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX Electronic address
    Urology 85:616-20. 2015
    ..To evaluate the effect of finasteride on serum androst-4-ene-3,17-dione (androstenedione) and its association with prostate cancer risk among subjects who participated in the Prostate Cancer Prevention Trial...
  2. pmc Serum estrogen levels and prostate cancer risk in the prostate cancer prevention trial: a nested case-control study
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA
    Cancer Causes Control 22:1121-31. 2011
    ..Finasteride reduces prostate cancer risk by blocking the conversion of testosterone to dihydrotestosterone. However, whether finasteride affects estrogens levels or change in estrogens affects prostate cancer risk is unknown...
  3. doi request reprint Statin induces apoptosis and cell growth arrest in prostate cancer cells
    Ashraful Hoque
    Department of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer Epidemiol Biomarkers Prev 17:88-94. 2008
    ..Future studies should focus on examining statins and other apoptosis-inducing drugs (e.g., cyclooxygenase-2 inhibitors or curcumin) together to assess their efficacy in prevention of prostate cancer...
  4. pmc Prognostic significance of differentially expressed miRNAs in esophageal cancer
    Yuxin Hu
    Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX77030, USA
    Int J Cancer 128:132-43. 2011
    ..Our data indicate that further evaluation of miR-30e and miR-16-2 as prognostic biomarkers is warranted in patients with esophageal adenocarcinoma. In addition, the role of miR-34a in esophageal cancer also warrants further study...
  5. pmc Repeat polymorphisms in estrogen metabolism genes and prostate cancer risk: results from the Prostate Cancer Prevention Trial
    Li Tang
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Carcinogenesis 32:1500-6. 2011
    ....
  6. ncbi request reprint Tumor-suppressive effect of retinoid receptor-induced gene-1 (RRIG1) in esophageal cancer
    Jie Huang
    Department of Clinical Cancer Prevention, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer Res 67:1589-93. 2007
    ..g., cyclin D1, phosphorylated Rb, and E2F). RRIG1-transfected sublines also inhibited tumor development in nude mice. The results of this study indicate that RRIG1 plays a role in suppressing tumorigenesis...
  7. pmc Antitumor effect of retinoic acid receptor-beta2 associated with suppression of cyclooxygenase-2
    Shumei Song
    Department of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer Prev Res (Phila) 2:274-80. 2009
    ..Thus, further studies will determine whether manipulation of COX-2 expression in different cancers can antagonize RAR-beta2 activity...
  8. ncbi request reprint Increased retinoic acid receptor-beta4 correlates in vivo with reduced retinoic acid receptor-beta2 in esophageal squamous cell carcinoma
    Xiao Chun Xu
    Department of Clinical Cancer Prevention, Unit 1360, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer Epidemiol Biomarkers Prev 14:826-9. 2005
    ..These are the first in vivo expression patterns of RAR-beta2 and RAR-beta4 reported in humans or animals and support the in vitro data on these isoforms and their contrasting biological effects in human carcinogenesis...
  9. pmc Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial
    Bora Gurel
    Authors Affiliations Departments of Pathology and Immunology The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins School of Medicine Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore Division of Cancer Prevention, Department of Health and Human Services, National Cancer Institute, NIH, Bethesda, Maryland University of Colorado School of Medicine, Aurora, Colorado Department of Urology, University of Texas Health Sciences Center San Antonio, San Antonio Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas SWOG Statistical Center Cancer Prevention Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington Moores Cancer Center, University of California San Diego, La Jolla, California and Division of Public Health Sciences and The Alvin J Siteman Cancer Center, Department of Surgery, Washington University School of Medicine, St Louis, Missouri
    Cancer Epidemiol Biomarkers Prev 23:847-56. 2014
    ..Chronic inflammation is hypothesized to influence prostate cancer development, although a definitive link has not been established...
  10. ncbi request reprint Loss of the expression of the tumor suppressor gene ARHI is associated with progression of breast cancer
    Lin Wang
    Departments of Experimental Therapeutics L W, R Z L, J Y, Z L, A N, R C B, Y Y, Clinical Cancer Prevention A H, S M L, and Pathology J L, A A S, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030
    Clin Cancer Res 9:3660-6. 2003
    ..This study investigated the relationship of ARHI expression to the progression of breast cancer...
  11. pmc Inverse relationship between 15-lipoxygenase-2 and PPAR-gamma gene expression in normal epithelia compared with tumor epithelia
    Vemparala Subbarayan
    Department of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Neoplasia 7:280-93. 2005
    ..These results suggest that feedback mechanisms may contribute to the loss of 15-LOX-2 pathway components, which coincide with an increase in PPAR-gamma in many epithelial cancers...
  12. pmc Inhibition of farnesoid X receptor controls esophageal cancer cell growth in vitro and in nude mouse xenografts
    Baoxiang Guan
    Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Cancer 119:1321-9. 2013
    ..The authors investigated the role of FXR expression and activity in esophageal cancer initiation and growth...
  13. ncbi request reprint Phase II clinical trial of N-(4-Hydroxyphenyl)retinamide and tamoxifen administration before definitive surgery for breast neoplasia
    S Eva Singletary
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 8:2835-42. 2002
    ..Surrogate end point biomarkers (SEBs) that can be measured in ductal carcinoma in situ or early-stage invasive cancer are needed to improve the efficiency and reduce the cost of chemoprevention trials...
  14. ncbi request reprint Human telomerase reverse transcriptase mRNA is highly expressed in normal breast tissues and down-regulated in ductal carcinoma in situ
    Jinsong Liu
    Department of Pathology, Division of Pathology and Laboratory Medicine, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Oncol 24:879-84. 2004
    ....
  15. ncbi request reprint Loss of aurora A/STK15/BTAK overexpression correlates with transition of in situ to invasive ductal carcinoma of the breast
    Ashraful Hoque
    Department of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer Epidemiol Biomarkers Prev 12:1518-22. 2003
    ..Our data demonstrate that STK15 overexpression correlates with centrosome anomaly and aneuploidy in DCIS, and loss of STK15 overexpression is associated with progression of in situ to ductal invasive breast carcinoma...
  16. pmc Extraction of DNA from serum for high-throughput genotyping: findings from pilot studies within the Prostate Cancer Prevention Trial
    Ashraful Hoque
    University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Urology 71:967-70. 2008
    ..We conducted several pilot studies to identify methods for DNA extraction and high-throughput SNP genotyping of both white blood cell (WBC) and serum DNA that can be done centrally and reliably for large numbers of samples...
  17. ncbi request reprint Meeting Report: Fifth Annual AACR Frontiers in Cancer Prevention Research
    Ashraful Hoque
    Department of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Cancer Res 67:8989-93. 2007
    ....
  18. ncbi request reprint Increased 5-lipoxygenase expression and induction of apoptosis by its inhibitors in esophageal cancer: a potential target for prevention
    Ashraful Hoque
    Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Carcinogenesis 26:785-91. 2005
    ....
  19. ncbi request reprint Designing the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
    Scott M Lippman
    The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Natl Cancer Inst 97:94-102. 2005
    ....
  20. ncbi request reprint Her-2/neu gene amplification in ductal carcinoma in situ of the breast
    Ashraful Hoque
    Departments of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer Epidemiol Biomarkers Prev 11:587-90. 2002
    ..g., p21 and Rb) as markers of the risk of DCIS patients for invasive breast cancer and as molecular targets of chemoprevention in breast intraepithelial neoplasia...
  21. ncbi request reprint Polymorphisms in DNA repair genes and therapeutic outcomes of AML patients from SWOG clinical trials
    Nataliya Kuptsova
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Blood 109:3936-44. 2007
    ..With validation of results in larger samples, these findings could lead to optimizing individual chemotherapy options...
  22. ncbi request reprint Centralized blood processing for the selenium and vitamin E cancer prevention trial: effects of delayed processing on carotenoids, tocopherols, insulin-like growth factor-I, insulin-like growth factor binding protein 3, steroid hormones, and lymphocyte vi
    Alan R Kristal
    Cancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 14:727-30. 2005
    ..Longer processing delays, however, have small but statistically significant effects on many analytes and substantially decrease lymphocyte viability...
  23. ncbi request reprint The evolution of the PCPT from clinical to molecular analyses
    Ashraful Hoque
    Nat Clin Pract Oncol 3:581. 2006

Research Grants1

  1. Estrogen Metabolism and Action in Prostate Cancer Etiology in PCPT
    Ashraful Hoque; Fiscal Year: 2007
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