Shiaoching Gong

Summary

Affiliation: The Rockefeller University
Country: USA

Publications

  1. pmc Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis
    Shiaoching Gong
    The Rockefeller University, New York, New York, USA
    Nat Protoc 5:1678-96. 2010
  2. pmc Application of a translational profiling approach for the comparative analysis of CNS cell types
    Joseph P Doyle
    Laboratory of Molecular Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA
    Cell 135:749-62. 2008
  3. pmc Mouse transgenesis in a single locus with independent regulation for multiple fluorophores
    Joseph D Dougherty
    Laboratory of Molecular Biology, The Rockefeller University, New York, New York, United States of America
    PLoS ONE 7:e40511. 2012
  4. pmc A translational profiling approach for the molecular characterization of CNS cell types
    Myriam Heiman
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065, USA
    Cell 135:738-48. 2008
  5. pmc Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication
    Shiaoching Gong
    Laboratory of Molecular Biology, The Rockefeller University, New York, New York 10021, USA
    Genome Res 12:1992-8. 2002
  6. ncbi request reprint Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs
    Shiaoching Gong
    Gene Expression Nervous System Atlas Project, Howard Hughes Medical Institute, The Rockefeller University, New York, New York 10021, USA
    J Neurosci 27:9817-23. 2007
  7. pmc Production of green fluorescent protein transgenic embryonic stem cells using the GENSAT bacterial artificial chromosome library
    Mark J Tomishima
    Developmental Biology Program, Sloan Kettering Institute, New York, New York 10021, USA
    Stem Cells 25:39-45. 2007
  8. ncbi request reprint A gene expression atlas of the central nervous system based on bacterial artificial chromosomes
    Shiaoching Gong
    GENSAT Project, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, Box 260, New York 10021, USA
    Nature 425:917-25. 2003
  9. pmc Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs
    Helen S Bateup
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Ave, New York, New York 10065, USA
    Nat Neurosci 11:932-9. 2008
  10. doi request reprint Modification of bacterial artificial chromosomes (BACs) and preparation of intact BAC DNA for generation of transgenic mice
    Shiaoching Gong
    Rockefeller University, New York, New York, USA
    Curr Protoc Neurosci . 2005

Collaborators

Detail Information

Publications10

  1. pmc Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis
    Shiaoching Gong
    The Rockefeller University, New York, New York, USA
    Nat Protoc 5:1678-96. 2010
    ..CNS anatomical expression maps of the mice are available to the public at http://www.gensat.org/...
  2. pmc Application of a translational profiling approach for the comparative analysis of CNS cell types
    Joseph P Doyle
    Laboratory of Molecular Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA
    Cell 135:749-62. 2008
    ..This resource will enable a wide spectrum of molecular and mechanistic studies of both well-known and previously uncharacterized neural cell populations...
  3. pmc Mouse transgenesis in a single locus with independent regulation for multiple fluorophores
    Joseph D Dougherty
    Laboratory of Molecular Biology, The Rockefeller University, New York, New York, United States of America
    PLoS ONE 7:e40511. 2012
    ..This generic solution should permit more sophisticated experimental manipulations to assess functional interactions amongst populations of cell types in vivo in a more rapid and efficient manner...
  4. pmc A translational profiling approach for the molecular characterization of CNS cell types
    Myriam Heiman
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10065, USA
    Cell 135:738-48. 2008
    ....
  5. pmc Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication
    Shiaoching Gong
    Laboratory of Molecular Biology, The Rockefeller University, New York, New York 10021, USA
    Genome Res 12:1992-8. 2002
    ..This new system has been used to modify a dozen BACs. It is well suited for efficient production of modified BACs for use in a variety of in vivo studies...
  6. ncbi request reprint Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs
    Shiaoching Gong
    Gene Expression Nervous System Atlas Project, Howard Hughes Medical Institute, The Rockefeller University, New York, New York 10021, USA
    J Neurosci 27:9817-23. 2007
  7. pmc Production of green fluorescent protein transgenic embryonic stem cells using the GENSAT bacterial artificial chromosome library
    Mark J Tomishima
    Developmental Biology Program, Sloan Kettering Institute, New York, New York 10021, USA
    Stem Cells 25:39-45. 2007
    ..Our protocols provide a simple and efficient strategy to utilize the whole GENSAT BAC library to create hundreds of novel fluorescent cell lines for use in ES cell biology...
  8. ncbi request reprint A gene expression atlas of the central nervous system based on bacterial artificial chromosomes
    Shiaoching Gong
    GENSAT Project, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, Box 260, New York 10021, USA
    Nature 425:917-25. 2003
    ..The atlas, library of BAC vectors and BAC transgenic mice generated in this screen provide a rich resource that allows a broad array of investigations not previously available to the neuroscience community...
  9. pmc Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs
    Helen S Bateup
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Ave, New York, New York 10065, USA
    Nat Neurosci 11:932-9. 2008
    ..Furthermore, we found that a variety of drugs that target the striatum have cell type-specific effects that previous methods were not able to discern...
  10. doi request reprint Modification of bacterial artificial chromosomes (BACs) and preparation of intact BAC DNA for generation of transgenic mice
    Shiaoching Gong
    Rockefeller University, New York, New York, USA
    Curr Protoc Neurosci . 2005
    ..Since BAC DNA is prone to degradation, which may introduce positional effects in transgenic mice, two methods are given for purification of intact BAC DNA for subsequent microinjection...