Brian T Fisher

Summary

Affiliation: The Children's Hospital of Philadelphia
Country: USA

Publications

  1. doi request reprint Cefepime and mortality in pediatric acute myelogenous leukemia: a retrospective cohort study
    Brian T Fisher
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, and Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Pediatr Infect Dis J 28:971-5. 2009
  2. pmc Epidemiology and potential preventative measures for viral infections in children with malignancy and those undergoing hematopoietic cell transplantation
    Brian T Fisher
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatr Blood Cancer 59:11-5. 2012
  3. doi request reprint Hospitalizations for coccidioidomycosis at forty-one children's hospitals in the United States
    Brian T Fisher
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Pediatr Infect Dis J 29:243-7. 2010
  4. pmc Risk factors for renal failure in pediatric patients with acute myeloid leukemia: a retrospective cohort study
    Brian T Fisher
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatr Blood Cancer 55:655-61. 2010
  5. pmc Establishing a high-risk neuroblastoma cohort using the Pediatric Health Information System Database
    Ami V Desai
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania Center for Pharmacoepidemiology Research and Training, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
    Pediatr Blood Cancer 61:1129-31. 2014
  6. pmc Induction mortality, ATRA administration, and resource utilization in a nationally representative cohort of children with acute promyelocytic leukemia in the United States from 1999 to 2009
    Brian T Fisher
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania Center for Pediatric Clinical Effectiveness, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    Pediatr Blood Cancer 61:68-73. 2014
  7. pmc Early discharge as a mediator of greater ICU-level care requirements in patients not enrolled on the AAML0531 clinical trial: a Children's Oncology Group report
    Kelly D Getz
    The Children s Hospital of Philadelphia, 3535 Market Street, Philadelphia, Pennsylvania, 19104
    Cancer Med 5:2412-6. 2016
  8. pmc Dexrazoxane exposure and risk of secondary acute myeloid leukemia in pediatric oncology patients
    Alix E Seif
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania Department of Pediatrics, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
    Pediatr Blood Cancer 62:704-9. 2015
  9. pmc Induction mortality and resource utilization in children treated for acute myeloid leukemia at free-standing pediatric hospitals in the United States
    Marko Kavcic
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Cancer 119:1916-23. 2013
  10. pmc Leveraging administrative data to monitor rituximab use in 2875 patients at 42 freestanding children's hospitals across the United States
    Marko Kavcic
    Division of Oncology, Center for Pediatric Clinical Effectiveness, The Children s Hospital of Philadelphia, and Department of Pediatrics, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Pediatr 162:1252-8, 1258.e1. 2013

Collaborators

Detail Information

Publications34

  1. doi request reprint Cefepime and mortality in pediatric acute myelogenous leukemia: a retrospective cohort study
    Brian T Fisher
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, and Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Pediatr Infect Dis J 28:971-5. 2009
    ..We evaluated the association of cefepime and other beta-lactam antibiotic exposures with all cause in-hospital mortality in pediatric AML patients...
  2. pmc Epidemiology and potential preventative measures for viral infections in children with malignancy and those undergoing hematopoietic cell transplantation
    Brian T Fisher
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatr Blood Cancer 59:11-5. 2012
    ..Additionally, infection control practices specific to this patient population are discussed. A comprehensive approach utilizing each of these can be effective at reducing the negative impact of viral infections...
  3. doi request reprint Hospitalizations for coccidioidomycosis at forty-one children's hospitals in the United States
    Brian T Fisher
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Pediatr Infect Dis J 29:243-7. 2010
    ..We describe the characteristics of initial and subsequent hospitalizations in children with coccidioidomycosis...
  4. pmc Risk factors for renal failure in pediatric patients with acute myeloid leukemia: a retrospective cohort study
    Brian T Fisher
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatr Blood Cancer 55:655-61. 2010
    ..This study aims to evaluate the rate of ARF in AML patients and to delineate the impact of age, race, various co-morbid conditions and antimicrobial agents on the development of ARF...
  5. pmc Establishing a high-risk neuroblastoma cohort using the Pediatric Health Information System Database
    Ami V Desai
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania Center for Pharmacoepidemiology Research and Training, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
    Pediatr Blood Cancer 61:1129-31. 2014
    ..1%; positive predictive value (PPV) 96.1%]. This cohort provides a data source for future comparative effectiveness and clinical epidemiology studies in high-risk neuroblastoma patients...
  6. pmc Induction mortality, ATRA administration, and resource utilization in a nationally representative cohort of children with acute promyelocytic leukemia in the United States from 1999 to 2009
    Brian T Fisher
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania Center for Pediatric Clinical Effectiveness, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    Pediatr Blood Cancer 61:68-73. 2014
    ....
  7. pmc Early discharge as a mediator of greater ICU-level care requirements in patients not enrolled on the AAML0531 clinical trial: a Children's Oncology Group report
    Kelly D Getz
    The Children s Hospital of Philadelphia, 3535 Market Street, Philadelphia, Pennsylvania, 19104
    Cancer Med 5:2412-6. 2016
    ..94), whereas the indirect effect mediated through early discharge was not (aOR = 1.07, 95% CI: 0.95, 1.19). Factors other than postchemotherapy discharge strategy drive the difference in ICU utilization by trial enrollment status. ..
  8. pmc Dexrazoxane exposure and risk of secondary acute myeloid leukemia in pediatric oncology patients
    Alix E Seif
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania Department of Pediatrics, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
    Pediatr Blood Cancer 62:704-9. 2015
    ..Published data about dexrazoxane-associated secondary AML are limited and conflicting. We sought to estimate the secondary AML risk in children receiving dexrazoxane after anthracycline exposure...
  9. pmc Induction mortality and resource utilization in children treated for acute myeloid leukemia at free-standing pediatric hospitals in the United States
    Marko Kavcic
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Cancer 119:1916-23. 2013
    ..Moreover, these trials likely underreport the clinical toxicities experienced by patients...
  10. pmc Leveraging administrative data to monitor rituximab use in 2875 patients at 42 freestanding children's hospitals across the United States
    Marko Kavcic
    Division of Oncology, Center for Pediatric Clinical Effectiveness, The Children s Hospital of Philadelphia, and Department of Pediatrics, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Pediatr 162:1252-8, 1258.e1. 2013
    ..To describe the pharmacoepidemiology of rituximab use in children and to estimate the frequency of infectious events within a 1-year period after rituximab exposure...
  11. doi request reprint Supportive care utilization and treatment toxicity in children with Down syndrome and acute lymphoid leukaemia at free-standing paediatric hospitals in the United States
    Elizabeth G Salazar
    Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
    Br J Haematol 174:591-9. 2016
    ..These findings highlight the importance of investigating the impact of these care variations and developing specific supportive care guidelines for this population. ..
  12. pmc A comparison of resource utilization following chemotherapy for acute myeloid leukemia in children discharged versus children that remain hospitalized during neutropenia
    Kelly D Getz
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania
    Cancer Med 4:1356-64. 2015
    ..Despite similar inpatient mortality to standard discharge patients, early discharge patients may be at greater risk for life-threatening chemotherapy-related complications, including infections...
  13. pmc Comparison of administrative/billing data to expected protocol-mandated chemotherapy exposure in children with acute myeloid leukemia: A report from the Children's Oncology Group
    Tamara P Miller
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania
    Pediatr Blood Cancer 62:1184-9. 2015
    ....
  14. pmc Outcome of pediatric acute myeloid leukemia patients receiving intensive care in the United States
    Shannon L Maude
    1Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, PA 2Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 3Department of Anesthesia and Critical Care Medicine, The Children s Hospital of Philadelphia, Philadelphia, PA 4Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 5Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, PA 6Center for Pediatric Clinical Effectiveness, The Children s Hospital of Philadelphia, Philadelphia, PA 7Bristol Myers Squibb, Hopewell, NJ 8Division of Haematology Oncology and Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada 9Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 10Division of Pediatric Critical Care Medicine, Department of Pediatrics and Public Health Sciences, Penn State Hershey Milton S Hershey Medical Center, Hershey, PA
    Pediatr Crit Care Med 15:112-20. 2014
    ..Our objective was to determine hospital mortality of pediatric acute myeloid leukemia patients requiring intensive care...
  15. pmc Accuracy of Adverse Event Ascertainment in Clinical Trials for Pediatric Acute Myeloid Leukemia
    Tamara P Miller
    Tamara P Miller, Yimei Li, Marko Kavcic, Yuan Shun V Huang, Rochelle Bagatell, Alix E Seif, Brian T Fisher, Peter C Adamson, and Richard Aplenc, The Children s Hospital of Philadelphia Yimei Li, Andrea B Troxel, Rochelle Bagatell, Alix E Seif, Brian T Fisher, Selina Luger, Peter C Adamson, and Richard Aplenc, University of Pennsylvania School of Medicine, Philadelphia, PA Lillian Sung, The Hospital for Sick Children, Toronto, Ontario, Canada Todd A Alonzo and Michael A Pulsipher, University of Southern California Michael A Pulsipher, Children s Hospital of Los Angeles, Los Angeles Todd A Alonzo and Robert Gerbing, Children s Oncology Group, Monrovia, CA Matt Hall, Children s Hospital Association, Overland Park, Kansas Marla H Daves, Children s Healthcare of Atlanta, Atlanta, Germany
    J Clin Oncol 34:1537-43. 2016
    ..This study sought to determine the accuracy of AE reporting for pediatric acute myeloid leukemia clinical trials and to test whether an external electronic data source can improve reporting...
  16. pmc Volume-Outcome Relationships in Pediatric Acute Lymphoblastic Leukemia: Association Between Hospital Pediatric and Pediatric Oncology Volume With Mortality and Intensive Care Resources During Initial Therapy
    Jennifer J Wilkes
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, PA Center for Pediatric Clinical Effectiveness, The Children s Hospital of Philadelphia, Philadelphia, PA Leonard Davis Institute of Health Economics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA Electronic address
    Clin Lymphoma Myeloma Leuk 16:404-410.e1. 2016
    ..We hypothesized an inverse relationship between volume and these outcomes...
  17. pmc Variation in Risk of Hospital-Onset Clostridium difficile Infection Across β-Lactam Antibiotics in Children With New-Onset Acute Lymphoblastic Leukemia
    Brian T Fisher
    Division of Infectious Diseases Center for Pediatric Clinical Effectiveness, The Children s Hospital of Philadelphia, Pennsylvania Department of Pediatrics, and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia
    J Pediatric Infect Dis Soc 3:329-35. 2014
    ..Antibiotic exposure is common among children with leukemia. However, limited data exist regarding the risk of Clostridium difficile infection (CDI) across anti-pseudomonal β-lactam antibiotics commonly used for fever and neutropenia...
  18. pmc Patient and hospital factors associated with induction mortality in acute lymphoblastic leukemia
    Alix E Seif
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania
    Pediatr Blood Cancer 61:846-52. 2014
    ..We sought to ascertain patient- and hospital-level factors associated with induction mortality...
  19. pmc Variation in hospital antibiotic prescribing practices for children with acute lymphoblastic leukemia
    Brian T Fisher
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA fi
    Leuk Lymphoma 54:1633-9. 2013
    ..Antibiotic use for children with newly diagnosed ALL varies widely across children's hospitals and is not explained by demographics or illness severity...
  20. pmc Ocular manifestations of candidemia in children
    Julie L Fierro
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Pediatr Infect Dis J 32:84-6. 2013
    ..This study found that ocular candidiasis is an uncommon but serious sight-threatening complication in pediatric patients with candidemia...
  21. doi request reprint Resource Utilization and Toxicities After Carboplatin/Etoposide/Melphalan and Busulfan/Melphalan for Autologous Stem Cell Rescue in High-Risk Neuroblastoma Using a National Administrative Database
    Ami V Desai
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania
    Pediatr Blood Cancer 63:901-7. 2016
    ..Resources required to support patients treated with ASCR conditioning regimens [carboplatin/etoposide/melphalan (CEM) and busulfan/melphalan (BuMel)] have not been directly compared...
  22. pmc Association of weekend admission with hospital length of stay, time to chemotherapy, and risk for respiratory failure in pediatric patients with newly diagnosed leukemia at freestanding US children's hospitals
    Elizabeth K Goodman
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania
    JAMA Pediatr 168:925-31. 2014
    ..In adult patients with leukemia, weekend admission is associated with increased inpatient mortality. It is unknown whether weekend diagnostic admissions in pediatric patients with leukemia demonstrate similar adverse outcomes...
  23. pmc Dexrazoxane use in pediatric patients with acute lymphoblastic or myeloid leukemia from 1999 and 2009: analysis of a national cohort of patients in the Pediatric Health Information Systems database
    Dana M Walker
    Division of Oncology, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Pediatr Blood Cancer 60:616-20. 2013
    ....
  24. doi request reprint Epidemiology of cryptococcal infection in hospitalized children
    Neha S Joshi
    Department of General Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Pediatr Infect Dis J 29:e91-5. 2010
    ..Despite the fact that many studies were conducted in adults, limited data exist for pediatric patients...
  25. pmc Treatment of Osteonecrosis in Children and Adolescents With Acute Lymphoblastic Leukemia
    Mallorie B Heneghan
    Department of General Pediatrics, The Children s Hospital of Philadelphia, Philadelphia, PA Electronic address
    Clin Lymphoma Myeloma Leuk 16:223-229.e2. 2016
    ..Cure rates for acute lymphoblastic leukemia (ALL) have improved, but as therapy has intensified, the burden of osteonecrosis (ON) has increased. Limited data exist regarding surgical interventions for pediatric ALL patients with ON...
  26. pmc Bortezomib Inpatient Prescribing Practices in Free-Standing Children's Hospitals in the United States
    Amanda M DiNofia
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 11:e0151362. 2016
    ..Bortezomib use in pediatrics is increasing for a variety of diseases. Variation in use exists across institutions. Further studies are needed to characterize bortezomib's efficacy in pediatric diseases. ..
  27. pmc Comparison of in-patient costs for children treated on the AAML0531 clinical trial: A report from the Children's Oncology Group
    Kelly D Getz
    The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania
    Pediatr Blood Cancer 62:1775-81. 2015
    ....
  28. pmc Predictors of antiemetic alteration in pediatric acute myeloid leukemia
    Jason L Freedman
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania
    Pediatr Blood Cancer 61:1798-805. 2014
    ..We aimed to describe such factors in children receiving treatment for acute myeloid leukemia (AML)...
  29. doi request reprint Parent willingness to remind health care workers to perform hand hygiene
    Genevieve L Buser
    Division of Infectious Diseases, Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Am J Infect Control 41:492-6. 2013
    ..Health care worker (HCW) hand hygiene (HH) is the core strategy to prevent health care-associated infections (HAI). Suboptimal HCW HH rates continue despite hospital efforts to increase compliance...
  30. pmc Comparative effectiveness of echinocandins versus fluconazole therapy for the treatment of adult candidaemia due to Candida parapsilosis: a retrospective observational cohort study of the Mycoses Study Group (MSG-12)
    Kathleen Chiotos
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    J Antimicrob Chemother 71:3536-3539. 2016
    ..We aimed to compare 30 day mortality in adults with C. parapsilosis candidaemia treated with echinocandins versus fluconazole...
  31. pmc Assembly of a cohort of children treated for acute myeloid leukemia at free-standing children's hospitals in the United States using an administrative database
    Marko Kavcic
    Division of Oncology, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Pediatr Blood Cancer 60:508-11. 2013
    ..7%). This cohort provides a reliable source for future comparative effectiveness and clinical epidemiology studies in pediatric AML...
  32. doi request reprint Comparative effectiveness of fungicidal vs. fungistatic therapies for the treatment of paediatric candidaemia
    Neika Vendetti
    Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Mycoses 59:173-8. 2016
    ..These data suggest that both agents can be considered definitive therapy for paediatric candidaemia. The results should be interpreted with caution given the small sample size. Larger cohort studies are needed. ..
  33. ncbi request reprint Antibiotic use in pediatric patients admitted to a referral hospital in Botswana
    Brian T Fisher
    Division of Infectious Diseases and Departments of Pediatrics and Anesthesia and Critical Care, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Am J Trop Med Hyg 81:129-31. 2009
    ..The results showed that the duration of prescribed therapy can be excessive. Recommendations for potential interventions to reduce antibiotic overuse in this setting are necessary...
  34. ncbi request reprint Treatment of invasive candidiasis in immunocompromised pediatric patients
    Brian T Fisher
    Department of Pediatrics, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Paediatr Drugs 10:281-98. 2008
    ....