Haiming Ding

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. pmc Sensitivity to the non-COX inhibiting celecoxib derivative, OSU03012, is p21(WAF1/CIP1) dependent
    Haiming Ding
    Department of Radiology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA
    Int J Cancer 123:2931-8. 2008
  2. doi request reprint Selective induction of apoptosis of human oral cancer cell lines by avocado extracts via a ROS-mediated mechanism
    Haiming Ding
    Department of Radiology, College of Medicine, 460 W 12th Avenue BRT 714, The Ohio State University, Columbus, Ohio 43210, USA
    Nutr Cancer 61:348-56. 2009
  3. doi request reprint OSU03012 activates Erk1/2 and Cdks leading to the accumulation of cells in the S-phase and apoptosis
    Haiming Ding
    Department of Radiology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA
    Int J Cancer 123:2923-30. 2008
  4. ncbi request reprint Chemopreventive characteristics of avocado fruit
    Haiming Ding
    Division of Radiobiology, Department of Radiology, College of Medicine, The Ohio State University, 2001 Polaris Pkwy, Columbus, OH 43240, USA
    Semin Cancer Biol 17:386-94. 2007
  5. ncbi request reprint Celecoxib derivatives induce apoptosis via the disruption of mitochondrial membrane potential and activation of caspase 9
    Haiming Ding
    Department of Radiology, College of Medicine and Public Health, The Ohio State University, Columbus, OH, USA
    Int J Cancer 113:803-10. 2005
  6. ncbi request reprint Inhibition of the growth of premalignant and malignant human oral cell lines by extracts and components of black raspberries
    Chunhua Han
    Department of Radiology, The Ohio State University, Columbus 43210, USA
    Nutr Cancer 51:207-17. 2005
  7. pmc Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21(Cip1) promoter
    Wei Guo Zhu
    Department of Internal Medicine Department of Pathology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio 43210, USA
    Mol Cell Biol 23:4056-65. 2003
  8. pmc Aliphatic acetogenin constituents of avocado fruits inhibit human oral cancer cell proliferation by targeting the EGFR/RAS/RAF/MEK/ERK1/2 pathway
    Steven M D'Ambrosio
    Department of Radiology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA
    Biochem Biophys Res Commun 409:465-9. 2011
  9. ncbi request reprint Piroxicam selectively inhibits the growth of premalignant and malignant human oral cell lines by limiting their progression through the S phase and reducing the levels of cyclins and AP-1
    Haiming Ding
    Department of Radiology, The Ohio State University, Columbus, OH, USA
    Int J Cancer 107:830-6. 2003
  10. doi request reprint Gastrin-releasing peptide receptor (GRPr) promotes EMT, growth, and invasion in canine prostate cancer
    Said M Elshafae
    Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio
    Prostate 76:796-809. 2016

Collaborators

Detail Information

Publications14

  1. pmc Sensitivity to the non-COX inhibiting celecoxib derivative, OSU03012, is p21(WAF1/CIP1) dependent
    Haiming Ding
    Department of Radiology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA
    Int J Cancer 123:2931-8. 2008
    ..These data suggest that p21(WAF1/CIP1) is an important factor in the sensitivity of cells to the growth inhibiting and apoptotic effects of OSU03012...
  2. doi request reprint Selective induction of apoptosis of human oral cancer cell lines by avocado extracts via a ROS-mediated mechanism
    Haiming Ding
    Department of Radiology, College of Medicine, 460 W 12th Avenue BRT 714, The Ohio State University, Columbus, Ohio 43210, USA
    Nutr Cancer 61:348-56. 2009
    ..These data suggest that perturbing the ROS levels in human oral cancer cell lines may be a key factor in selective apoptosis and molecular targeting for chemoprevention by phytochemicals...
  3. doi request reprint OSU03012 activates Erk1/2 and Cdks leading to the accumulation of cells in the S-phase and apoptosis
    Haiming Ding
    Department of Radiology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA
    Int J Cancer 123:2923-30. 2008
    ..OSU0312 may provide unique opportunities for cancer prevention and sensitization of cancer cells to S-phase modalities...
  4. ncbi request reprint Chemopreventive characteristics of avocado fruit
    Haiming Ding
    Division of Radiobiology, Department of Radiology, College of Medicine, The Ohio State University, 2001 Polaris Pkwy, Columbus, OH 43240, USA
    Semin Cancer Biol 17:386-94. 2007
    ..These studies suggest that individual and combinations of phytochemicals from the avocado fruit may offer an advantageous dietary strategy in cancer prevention...
  5. ncbi request reprint Celecoxib derivatives induce apoptosis via the disruption of mitochondrial membrane potential and activation of caspase 9
    Haiming Ding
    Department of Radiology, College of Medicine and Public Health, The Ohio State University, Columbus, OH, USA
    Int J Cancer 113:803-10. 2005
    ..This suggests that the modification of the celecoxib structure can lead to highly effective COX-independent growth inhibitory and apoptotic agents in chemoprevention and therapy...
  6. ncbi request reprint Inhibition of the growth of premalignant and malignant human oral cell lines by extracts and components of black raspberries
    Chunhua Han
    Department of Radiology, The Ohio State University, Columbus 43210, USA
    Nutr Cancer 51:207-17. 2005
    ....
  7. pmc Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21(Cip1) promoter
    Wei Guo Zhu
    Department of Internal Medicine Department of Pathology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio 43210, USA
    Mol Cell Biol 23:4056-65. 2003
    ..Our data suggest, for the first time, that hypermethylation around the consensus Sp1-binding sites may directly reduce Sp1/Sp3 binding, therefore leading to a reduced p21(Cip1) expression in response to depsipeptide treatment...
  8. pmc Aliphatic acetogenin constituents of avocado fruits inhibit human oral cancer cell proliferation by targeting the EGFR/RAS/RAF/MEK/ERK1/2 pathway
    Steven M D'Ambrosio
    Department of Radiology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA
    Biochem Biophys Res Commun 409:465-9. 2011
    ..The present data suggest that the potential anticancer activity of avocado fruits is due to a combination of specific aliphatic acetogenins that target two key components of the EGFR/RAS/RAF/MEK/ERK1/2 cancer pathway...
  9. ncbi request reprint Piroxicam selectively inhibits the growth of premalignant and malignant human oral cell lines by limiting their progression through the S phase and reducing the levels of cyclins and AP-1
    Haiming Ding
    Department of Radiology, The Ohio State University, Columbus, OH, USA
    Int J Cancer 107:830-6. 2003
    ....
  10. doi request reprint Gastrin-releasing peptide receptor (GRPr) promotes EMT, growth, and invasion in canine prostate cancer
    Said M Elshafae
    Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio
    Prostate 76:796-809. 2016
    ..This study examined the effects of a heterologous GRPr agonist, bombesin (BBN), on growth, motility, morphology, gene expression, and tumor phenotype of an osteoblastic canine prostate cancer cell line (Ace-1) in vitro and in vivo...
  11. doi request reprint A human GRPr-transfected Ace-1 canine prostate cancer model in mice
    Haiming Ding
    Department of Radiology, The Wright Center for Innovation in Biomolecular Imaging, The Wexner Medical Center, The Ohio State University, Columbus, Ohio
    Prostate 76:783-95. 2016
    ..A versatile drug screening system was developed to simplify early targeted drug discovery in mice and then translate readily from mice to a dog prostate cancer model that more fully replicates the features of human prostate cancer...
  12. doi request reprint A high-affinity near-infrared fluorescent probe to target bombesin receptors
    Ajay Shrivastava
    Department of Radiology, The Ohio State University, Columbus, OH, 43210, USA
    Mol Imaging Biol 16:661-9. 2014
    ..This study aimed to create new optical surgical navigation NIRF probes for prostate and breast cancers...
  13. pmc Heterobivalent dual-target probe for targeting GRP and Y1 receptors on tumor cells
    Ajay Shrivastava
    Department of Radiology, The Ohio State University, Columbus, OH 43210, USA
    Bioorg Med Chem Lett 23:687-92. 2013
    ..In conclusion, it is possible to construct a single DO3A chelate containing probe that can target both GRPR and Y1 on human tumor cells...
  14. ncbi request reprint P21 response to DNA damage induced by genistein and etoposide in human lung cancer cells
    Haiming Ding
    Arthur James Cancer Hospital and Richard Solove Research Institute, Comprehensive Cancer Center, and Department of Internal Medicine, The Ohio State University, Columbus, OH 43210 1240, USA
    Biochem Biophys Res Commun 305:950-6. 2003
    ..Our results suggest different mechanisms participate in genistein and etoposide induced p21(WAF1/Cip1) expression...