F S Dhabhar
Affiliation: The Ohio State University
- Stress-induced enhancement of skin immune function: A role for gamma interferonF S Dhabhar
Department of Oral Biology, Ohio State University, Columbus, OH 43210, USA
Proc Natl Acad Sci U S A 97:2846-51. 2000..g., resistance to viral, bacterial, parasitic, and fungal infections) or pathological (e.g., autoimmune reactions and contact sensitivity reactions such as that to poison ivy) immune responses...
- Acute stress enhances while chronic stress suppresses skin immunity. The role of stress hormones and leukocyte traffickingF S Dhabhar
College of Dentistry and College of Medicine, Ohio State University, 4179 Postle Hall, 305 W 12th Ave, 192, Columbus, OH 43210 1241, USA
Ann N Y Acad Sci 917:876-93. 2000..g., wounding or infection) that may be imposed by a stressor (e.g., an aggressor). Thus, during acute stress, the brain may send a warning signal to the immune system, just as it does to other fight/flight systems in the body...
- Short-term stress experienced at time of immunization induces a long-lasting increase in immunologic memoryFirdaus S Dhabhar
Department of Oral Biology, College of Dentistry, The Ohio State University, 4179 Postle Hall, 305 West 12th Avenue, Columbus, OH 43210, USA
Am J Physiol Regul Integr Comp Physiol 289:R738-44. 2005....
- Stress as an endogenous adjuvant: augmentation of the immunization phase of cell-mediated immunityKavitha Viswanathan
Department of Biology, College of Dentistry, Ohio State University, 4179 Postle Hall, 305 West 12th Avenue, Columbus, OH 43210, USA
Int Immunol 17:1059-69. 2005..g. infection and wounding by a predator), but may also contribute to stress-induced exacerbation of inflammatory and autoimmune diseases...
- Stressor-specific alterations in corticosterone and immune responses in miceStephanie L Bowers
Departments of Psychology, Neuroscience, and Institute for Behavioral Medicine Research, The Ohio State University, Columbus, OH 43210, USA
Brain Behav Immun 22:105-13. 2008..The variation observed in the measured immune responses may reflect differential glucocorticoid activation, differential metabolic adjustments, or both processes in response to specific stressors...
- Stress-induced modulation of NK activity during influenza viral infection: role of glucocorticoids and opioidsRaymond J Tseng
Department of Oral Biology, Ohio State University College of Dentistry, Columbus, OH, USA
Brain Behav Immun 19:153-64. 2005....
- Immune and stress responses in C57BL/6 and C3H/HeN mouse strains following photoperiod manipulationMichelle L Gatien
Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
Neuro Endocrinol Lett 25:267-72. 2004..The purpose of this study was to determine whether two different strains of mice, that are reproductively unresponsive to photoperiod, adjust immune function in response to photoperiod...
- Effects of photoperiod history on immune responses to intermediate day lengths in Siberian hamsters (Phodopus sungorus)Brian J Prendergast
Departments of Psychology and Neuroscience, The Ohio State University, Columbus, OH 43210, USA
J Neuroimmunol 149:31-9. 2004..The data suggest that photoperiodic mechanisms that enhance and suppress several aspects of immunity in young-adult hamsters are not responsive to prenatally communicated photoperiod history information...
- Stress-induced enhancement of leukocyte trafficking into sites of surgery or immune activationKavitha Viswanathan
Department of Oral Biology, College of Dentistry, Ohio State University, Columbus, OH 43210, USA
Proc Natl Acad Sci U S A 102:5808-13. 2005....
- Chronic stress and susceptibility to skin cancerAlison N Saul
Colleges of Medicine and Public Health, The Ohio State University, Columbus, OH, USA
J Natl Cancer Inst 97:1760-7. 2005..Therefore, we investigated potential mediators of a stress-induced increase in emergence and progression of UV-induced squamous cell carcinoma...
- Photoperiod affects the expression of sex and species differences in leukocyte number and leukocyte trafficking in congeneric hamstersS D Bilbo
Department of Psychological and Brain Sciences, The Johns Hopkins University, Baltimore, MD 21218, USA
Psychoneuroendocrinology 28:1027-43. 2003..Our results suggest that interactions among social factors and the environment play a significant role in modulating sex and seasonal alterations in leukocyte numbers and stress responses...
- Skeleton photoperiods alter delayed-type hypersensitivity responses and reproductive function of Siberian hamsters (Phodopus sungorus)M L Gatien
Department of Psychology, Institute for Behavioral Medicine Research, The Ohio State University, Columbus, OH 43210, USA
J Neuroendocrinol 17:733-9. 2005..DTH responses were equivalent in both long-day groups. These results suggest that the influences of day length on immune function potentially are due to circadian photoperiodic time measurement systems...
- Short day lengths augment stress-induced leukocyte trafficking and stress-induced enhancement of skin immune functionStaci D Bilbo
Department of Psychology, The Johns Hopkins University, Baltimore, MD 21218, USA
Proc Natl Acad Sci U S A 99:4067-72. 2002..These results suggest that photoperiod may provide a useful cue by which stressors in the environment may be anticipated to adjust the repertoire of available immune cells and increase survival likelihood...
- Acute stress evokes selective mobilization of T cells that differ in chemokine receptor expression: a potential pathway linking immunologic reactivity to cardiovascular diseaseJos A Bosch
Periodontology Section, The Ohio State University, College of Dentistry, 305 West 12th Avenue, P O Box 182357, Columbus, OH 43218, USA
Brain Behav Immun 17:251-9. 2003..This mechanism may help explain the link between stress, reactivity, and cardiovascular disease...
- Stress-induced augmentation of immune function--the role of stress hormones, leukocyte trafficking, and cytokinesFirdaus S Dhabhar
College of Dentistry, The Ohio State University Health Sciences Center, Columbus, OH 43210, USA
Brain Behav Immun 16:785-98. 2002....
- Modulation of natural killer cell activity by restraint stress during an influenza A/PR8 infection in miceJohn Hunzeker
Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, OH 43218, USA
Brain Behav Immun 18:526-35. 2004..The consequence of this effect was diminished NK cell function and enhanced viral replication...
- Stress, leukocyte trafficking, and the augmentation of skin immune functionFirdaus S Dhabhar
College of Dentistry College of Medicine, The Ohio State University, Columbus, Ohio 43210, USA
Ann N Y Acad Sci 992:205-17. 2003....
- Expression of glucocorticoid resistance following social stress requires a second signalRonit Avitsur
Section of Oral Biology, The Ohio State University, Columbus 43218 2357, USA
J Leukoc Biol 74:507-13. 2003..Together, these findings suggest that the expression of GC resistance in response to SDR requires a second signal that can be provided by ligation of TLR4...
- Social stress alters splenocyte phenotype and functionRonit Avitsur
Section of Oral Biology, The Ohio State University Health Sciences Center, Columbus, OH, USA
J Neuroimmunol 132:66-71. 2002..Together, these findings indicate that social stress altered phenotype and function of splenic immune cells. These findings may have implications for the healing of bite wounds that are often associated with social stress in rodents...
- Social disruption-induced glucocorticoid resistance: kinetics and site specificityRonit Avitsur
Section of Oral Biology, The Ohio State University Health Sciences Center, Columbus, OH 43218, USA
J Neuroimmunol 124:54-61. 2002..In contrast, SDR did not alter cytokine secretion from peritoneal mononuclear cells treated with corticosterone. These findings suggest that SDR-induced GC resistance may be restricted to specific sites such as the spleen...
- Social experience alters the response to social stress in miceRonit Avitsur
Section of Oral Biology, College of Dentistry, The Ohio State University, 305 West 12th Avenue, PO Box 182357, Columbus, OH 43218 2357, USA
Brain Behav Immun 17:426-37. 2003..Together, these findings indicate that environmental factors, such as previous social experiences, may alter the susceptibility to the effects of future social stress in inbred mice...
- Enhanced cellular immune response in women with PTSD related to childhood abuseMargaret Altemus
Department of Psychiatry, Weill Medical College, Cornell University, 1300 York Avenue, Box 244, New York, NY 10021, USA
Am J Psychiatry 160:1705-7. 2003....
- Pineal-dependent and -independent effects of photoperiod on immune function in Siberian hamsters (Phodopus sungorus)Jarvi C Wen
Department of Psychology and Institute for Mind and Biology, University of Chicago, Chicago, IL 60637, USA
Horm Behav 51:31-9. 2007..The pineal gland is required for photoperiodic regulation of circulating leukocytes and neural-immune interactions that mediate select aspects of sickness behaviors...
- Immune function in PTSDMargaret Altemus
Department of Psychiatry, Weill Medical College, Cornell University, Box 244, 1300 York Ave, New York, NY 10021, USA
Ann N Y Acad Sci 1071:167-83. 2006..These findings contrast with suppression of DTH and skin barrier function recovery in healthy volunteers in response to acute psychological stress...
- The adrenal gland is a source of stress-induced circulating IL-18Shuei Sugama
Department of Physiology, Nippon Medical School, 1 1 5 Sendagi Bunkyo ku, Tokyo 113 8602, Japan
J Neuroimmunol 172:59-65. 2006..The stress-induced increase in circulating IL-18 was abolished by adrenalectomy. These findings demonstrate that the adrenal gland is required to achieve elevation of circulating IL-18 during stress...
- Regulation of macrophage migration inhibitory factor expression by glucocorticoids in vivoGunter Fingerle-Rowson
Picower Institute for Medical Research, Manhasset, New York, USA
Am J Pathol 162:47-56. 2003..These findings suggest a role for MIF in both the homeostatic and physiological action of glucocorticoids in vivo...
- Gonadal hormone-dependent and -independent regulation of immune function by photoperiod in Siberian hamstersBrian J Prendergast
Department of Psychology, University of Chicago, Chicago, IL 60637, USA
Am J Physiol Regul Integr Comp Physiol 294:R384-92. 2008..Thus, photoperiod affects the immune system and neural-immune interactions underlying sickness behaviors via gonadal hormone-dependent and -independent mechanisms...
- The influence of bio-behavioural factors on tumour biology: pathways and mechanismsMichael H Antoni
Department of Psychology, Sylvestor Cancer Center, University of Miami, P O Box 248185, Coral Gables, Florida 33124, USA
Nat Rev Cancer 6:240-8. 2006....
- How psychological stress via hormones and nerve fibers may exacerbate rheumatoid arthritisRainer H Straub
Laboratory of Neuroendocrinoimmunology, Division of Rheumatology, Dept of Internal Medicine I, University Hospital Regensburg, 93042 Regensburg, Germany
Arthritis Rheum 52:16-26. 2005
- Metabonomic studies on the physiological effects of acute and chronic psychological stress in Sprague-Dawley ratsClaire R Teague
Department of Biomolecular Medicine, SORA Division, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, United Kingdom
J Proteome Res 6:2080-93. 2007..This study indicates the potential of using NMR-based metabonomic strategies for the characterization of endogenous metabolic perturbations induced by psychological stressors and lifestyle choices...
- Accelerated telomere shortening in response to life stressElissa S Epel
Department of Psychiatry, University of California, 3333 California Street, Suite 465, San Francisco, CA 94143, USA
Proc Natl Acad Sci U S A 101:17312-5. 2004..These findings have implications for understanding how, at the cellular level, stress may promote earlier onset of age-related diseases...