Laura F DeFina
Affiliation: The Cooper Institute
- Cardiorespiratory Fitness and Highly Sensitive Cardiac Troponin Levels in a Preventive Medicine CohortLaura F DeFina
Cooper Institute, Dallas, TX
J Am Heart Assoc 5:. 2016..A link of low CRF to subclinical cardiac injury may explain this association. We hypothesized that CRF would be inversely associated with hs-cTnT measured in healthy adults over age 50...
- Physical activity versus cardiorespiratory fitness: two (partly) distinct components of cardiovascular health?Laura F DeFina
The Cooper Institute, Dallas, TX Electronic address
Prog Cardiovasc Dis 57:324-9. 2015..Finally, the benefits, methodology, and utilization are compared and contrasted to better understand the two (partly) distinct components and their impact on CV health...
- Cardiorespiratory fitness and coronary artery calcification in womenLaura Defina
The Cooper Institute, 12330 Preston Road, Dallas, TX 75230, USA Electronic address
Atherosclerosis 233:648-53. 2014..The goal of this study was to assess the relationship between coronary artery calcification as a measure of atherosclerotic burden and fitness in a large population of generally healthy women...
- Fasting glucose, obesity, and metabolic syndrome as predictors of type 2 diabetes: the Cooper Center Longitudinal StudyLaura F DeFina
The Cooper Institute, Dallas, TX 75230, USA
J Investig Med 60:1164-8. 2012..To determine risk for type 2 diabetes in subjects with fasting glucose levels in the ranges of normoglycemia, mild hyperglycemia, and intermediate hyperglycemia and to assess the effect of obesity and metabolic syndrome on this risk...
- The association between midlife cardiorespiratory fitness levels and later-life dementia: a cohort studyLaura F DeFina
The Cooper Institute and University of Texas Southwestern Medical Center, Dallas, Texas, USA
Ann Intern Med 158:162-8. 2013..Primary prevention of Alzheimer disease and other types of dementia (all-cause dementia) is an important public health goal. Evidence to date is insufficient to recommend any lifestyle change to prevent or delay the onset of dementia...
- Effects of omega-3 supplementation in combination with diet and exercise on weight loss and body compositionLaura F DeFina
The Cooper Institute, Dallas, TX 75230, USA
Am J Clin Nutr 93:455-62. 2011..In addition to the metabolic and cardiovascular benefits of omega-3 (n-3) fatty acids, several studies have suggested an added weight loss-enhancing benefit to this supplement...
- Asthma and depression: the Cooper Center Longitudinal StudyTimothy D Trojan
Allergy and Immunology Division, Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas
Ann Allergy Asthma Immunol 112:432-6. 2014..Prior research suggests a possible association between asthma and depression...
- Progression of CAC Score and Risk of Incident CVDNina B Radford
Cooper Clinic, Dallas, Texas
JACC Cardiovasc Imaging 9:1420-1429. 2016..The authors sought to determine the relative contributions of baseline coronary artery calcification (CAC), follow-up CAC, and CAC progression on incident cardiovascular disease (CVD)...
- Association between omega-3 fatty acids and serum prostate-specific antigenLaura F DeFina
a The Cooper Institute, Dallas, Texas, USA
Nutr Cancer 68:58-62. 2016..Given that the study had >80% power to detect an odds ratio <0.9 or >1.1, we conclude that associations between O3FAs and PSA levels are either nonexistent or quite weak in the population that this healthy sample represents. ..
- Association of triglyceride-to-high density lipoprotein cholesterol ratio to cardiorespiratory fitness in menGloria Lena Vega
Departments of Clinical Nutrition and Internal Medicine, Center for Human Nutrition of the University of Texas Southwestern Medical Center, Dallas, TX, USA The Veterans Administration North Texas Health Care System, Dallas, TX, USA Electronic address
J Clin Lipidol 10:1414-1422.e1. 2016..Both triglyceride-to-high density lipoprotein cholesterol (TG/HDL-C) and cardiorespiratory fitness (CRF) impart risk for all-cause morbidity and mortality independently of conventional risk factors...
- Secular change in cardiorespiratory fitness of men: Cooper Center Longitudinal StudyBenjamin L Willis
The Cooper Institute, Dallas, TX 75230, USA
Med Sci Sports Exerc 43:2134-9. 2011..During the last four decades, national guidelines for physical activity and fitness have emerged in an ongoing effort to improve health outcomes through enhanced CRF risk profiles...
- Cardiorespiratory fitness and long-term survival in "low-risk" adultsCarolyn E Barlow
The Cooper Institute, University of Texas Southwestern Medical Center, Dallas, TX C E B, L F D
J Am Heart Assoc 1:e001354. 2012..Prognostic factors of long-term cardiovascular risk are needed for low-risk subjects who make up the largest percentage of the US population...
- Triglyceride-to-high-density-lipoprotein-cholesterol ratio is an index of heart disease mortality and of incidence of type 2 diabetes mellitus in menGloria Lena Vega
From the Center for Human Nutrition, University of Texas Southwestern Medical Center, the Veterans Affairs Medical Center at Dallas and The Cooper Institute, Dallas, TX
J Investig Med 62:345-9. 2014..This study examines the relationships of TG/HDL-C ratio to mortality from all causes, coronary heart disease (CHD), or cardiovascular disease (CVD)...
- Association of cardiorespiratory fitness with left ventricular remodeling and diastolic function: the Cooper Center Longitudinal StudyStephanie K Brinker
Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, Texas
JACC Heart Fail 2:238-46. 2014..This study sought to compare the cross-sectional associations between fitness and echocardiographic measures of cardiac structure and function...
- High Cardiorespiratory Fitness Is Associated with Reduced Risk of Low Bone Density in Postmenopausal WomenLaura F DeFina
1 The Cooper Institute, Dallas, Texas
J Womens Health (Larchmt) 25:1073-1080. 2016..The goal of this study was to determine the association between cardiorespiratory fitness (CRF) and bone mineral density (BMD) of the femoral neck (FN) in postmenopausal women using existing Cooper Center Longitudinal Study data...
- The association between midlife cardiorespiratory fitness and later life chronic kidney disease: The Cooper Center Longitudinal StudyLaura F DeFina
The Cooper Institute, Dallas, TX, United States
Prev Med 89:178-83. 2016..Chronic kidney disease (CKD) is a major public health problem, particularly in older age and in those with diabetes mellitus (DM), with high comorbidity and treatment costs...
- Association of Ideal Cardiovascular Health and Long-term Healthcare CostsBenjamin L Willis
The Cooper Institute, Dallas, Texas Electronic address
Am J Prev Med 49:678-85. 2015..The association between CV health and healthcare costs has not been reported; therefore, we evaluated the association between CV health profile and later-life healthcare costs...
- Effect of fitness on incident diabetes from statin use in primary preventionNina B Radford
Cooper Clinic, Dallas, TX, USA
Atherosclerosis 239:43-9. 2015..To assess the effect of cardiorespiratory fitness on the association between the initiation of statin therapy and incident diabetes...
- The Relationship Between Cardiorespiratory Fitness and Bone Mineral Density in Men: A Cross-sectional StudyHeather M Wainstein
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX
Mayo Clin Proc 91:726-34. 2016..To determine the relationship between estimated cardiorespiratory fitness (CRF) and femoral neck (FN) bone mineral density (BMD) in men...
- Depressive symptoms and metabolic syndrome in preventive healthcare: the Cooper Center longitudinal studyCara East
Soltero Cardiovascular Research Center, Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas, USA
Metab Syndr Relat Disord 8:451-7. 2010..The association among these factors in a generally healthy, active population with access to health care is not well defined...
- Psychometric evaluation of the Montreal Cognitive Assessment (MoCA) in three diverse samplesIra H Bernstein
Department of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9129, USA
Clin Neuropsychol 25:119-26. 2011..Although useful in large non-clinical studies, the MoCA is best suited to detect and quantify cognitive impairment in clinical patients...
- Relationship between serum homocysteine levels and depressive symptoms: the Cooper Center Longitudinal StudyPhillip Gu
Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390 8849, USA
J Clin Psychiatry 73:691-5. 2012..To resolve conflicting findings in studies that suggest a relationship between elevated serum HCY levels and depression, we examined the relationship between HCY levels and depressive symptoms in the largest sample studied to date...
- Association Between Sitting Time and Cardiometabolic Risk Factors After Adjustment for Cardiorespiratory Fitness, Cooper Center Longitudinal Study, 2010-2013Carolyn E Barlow
The Cooper Institute, Dallas, Texas
Prev Chronic Dis 13:E181. 2016..Our study examined the association between sitting time and cardiometabolic risk factors after adjustment for cardiorespiratory fitness (CRF)...
- Exercise outcomes in prevalent users of stimulant medicationsArthur N Westover
Department of Psychiatry, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA Department of Clinical Sciences, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA Electronic address
J Psychiatr Res 64:32-9. 2015..To compare users of stimulant medications with matched nonusers on exercise outcomes during a maximal treadmill exercise test...
- The relationship between asthma and self-reported anxiety in a predominantly healthy adult populationElan Gada
Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas
Ann Allergy Asthma Immunol 112:329-32. 2014..However, whether a link between milder asthma and anxiety exists remains unclear...