Laura F DeFina

Summary

Affiliation: The Cooper Institute
Country: USA

Publications

  1. pmc Cardiorespiratory Fitness and Highly Sensitive Cardiac Troponin Levels in a Preventive Medicine Cohort
    Laura F DeFina
    Cooper Institute, Dallas, TX
    J Am Heart Assoc 5:. 2016
  2. doi request reprint Physical activity versus cardiorespiratory fitness: two (partly) distinct components of cardiovascular health?
    Laura F DeFina
    The Cooper Institute, Dallas, TX Electronic address
    Prog Cardiovasc Dis 57:324-9. 2015
  3. doi request reprint Cardiorespiratory fitness and coronary artery calcification in women
    Laura Defina
    The Cooper Institute, 12330 Preston Road, Dallas, TX 75230, USA Electronic address
    Atherosclerosis 233:648-53. 2014
  4. doi request reprint Fasting glucose, obesity, and metabolic syndrome as predictors of type 2 diabetes: the Cooper Center Longitudinal Study
    Laura F DeFina
    The Cooper Institute, Dallas, TX 75230, USA
    J Investig Med 60:1164-8. 2012
  5. pmc The association between midlife cardiorespiratory fitness levels and later-life dementia: a cohort study
    Laura F DeFina
    The Cooper Institute and University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Ann Intern Med 158:162-8. 2013
  6. doi request reprint Effects of omega-3 supplementation in combination with diet and exercise on weight loss and body composition
    Laura F DeFina
    The Cooper Institute, Dallas, TX 75230, USA
    Am J Clin Nutr 93:455-62. 2011
  7. doi request reprint Asthma and depression: the Cooper Center Longitudinal Study
    Timothy D Trojan
    Allergy and Immunology Division, Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas
    Ann Allergy Asthma Immunol 112:432-6. 2014
  8. doi request reprint Progression of CAC Score and Risk of Incident CVD
    Nina B Radford
    Cooper Clinic, Dallas, Texas
    JACC Cardiovasc Imaging 9:1420-1429. 2016
  9. doi request reprint Association between omega-3 fatty acids and serum prostate-specific antigen
    Laura F DeFina
    a The Cooper Institute, Dallas, Texas, USA
    Nutr Cancer 68:58-62. 2016
  10. doi request reprint Association of triglyceride-to-high density lipoprotein cholesterol ratio to cardiorespiratory fitness in men
    Gloria Lena Vega
    Departments of Clinical Nutrition and Internal Medicine, Center for Human Nutrition of the University of Texas Southwestern Medical Center, Dallas, TX, USA The Veterans Administration North Texas Health Care System, Dallas, TX, USA Electronic address
    J Clin Lipidol 10:1414-1422.e1. 2016

Collaborators

Detail Information

Publications25

  1. pmc Cardiorespiratory Fitness and Highly Sensitive Cardiac Troponin Levels in a Preventive Medicine Cohort
    Laura F DeFina
    Cooper Institute, Dallas, TX
    J Am Heart Assoc 5:. 2016
    ..A link of low CRF to subclinical cardiac injury may explain this association. We hypothesized that CRF would be inversely associated with hs-cTnT measured in healthy adults over age 50...
  2. doi request reprint Physical activity versus cardiorespiratory fitness: two (partly) distinct components of cardiovascular health?
    Laura F DeFina
    The Cooper Institute, Dallas, TX Electronic address
    Prog Cardiovasc Dis 57:324-9. 2015
    ..Finally, the benefits, methodology, and utilization are compared and contrasted to better understand the two (partly) distinct components and their impact on CV health...
  3. doi request reprint Cardiorespiratory fitness and coronary artery calcification in women
    Laura Defina
    The Cooper Institute, 12330 Preston Road, Dallas, TX 75230, USA Electronic address
    Atherosclerosis 233:648-53. 2014
    ..The goal of this study was to assess the relationship between coronary artery calcification as a measure of atherosclerotic burden and fitness in a large population of generally healthy women...
  4. doi request reprint Fasting glucose, obesity, and metabolic syndrome as predictors of type 2 diabetes: the Cooper Center Longitudinal Study
    Laura F DeFina
    The Cooper Institute, Dallas, TX 75230, USA
    J Investig Med 60:1164-8. 2012
    ..To determine risk for type 2 diabetes in subjects with fasting glucose levels in the ranges of normoglycemia, mild hyperglycemia, and intermediate hyperglycemia and to assess the effect of obesity and metabolic syndrome on this risk...
  5. pmc The association between midlife cardiorespiratory fitness levels and later-life dementia: a cohort study
    Laura F DeFina
    The Cooper Institute and University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Ann Intern Med 158:162-8. 2013
    ..Primary prevention of Alzheimer disease and other types of dementia (all-cause dementia) is an important public health goal. Evidence to date is insufficient to recommend any lifestyle change to prevent or delay the onset of dementia...
  6. doi request reprint Effects of omega-3 supplementation in combination with diet and exercise on weight loss and body composition
    Laura F DeFina
    The Cooper Institute, Dallas, TX 75230, USA
    Am J Clin Nutr 93:455-62. 2011
    ..In addition to the metabolic and cardiovascular benefits of omega-3 (n-3) fatty acids, several studies have suggested an added weight loss-enhancing benefit to this supplement...
  7. doi request reprint Asthma and depression: the Cooper Center Longitudinal Study
    Timothy D Trojan
    Allergy and Immunology Division, Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas
    Ann Allergy Asthma Immunol 112:432-6. 2014
    ..Prior research suggests a possible association between asthma and depression...
  8. doi request reprint Progression of CAC Score and Risk of Incident CVD
    Nina B Radford
    Cooper Clinic, Dallas, Texas
    JACC Cardiovasc Imaging 9:1420-1429. 2016
    ..The authors sought to determine the relative contributions of baseline coronary artery calcification (CAC), follow-up CAC, and CAC progression on incident cardiovascular disease (CVD)...
  9. doi request reprint Association between omega-3 fatty acids and serum prostate-specific antigen
    Laura F DeFina
    a The Cooper Institute, Dallas, Texas, USA
    Nutr Cancer 68:58-62. 2016
    ..Given that the study had >80% power to detect an odds ratio <0.9 or >1.1, we conclude that associations between O3FAs and PSA levels are either nonexistent or quite weak in the population that this healthy sample represents. ..
  10. doi request reprint Association of triglyceride-to-high density lipoprotein cholesterol ratio to cardiorespiratory fitness in men
    Gloria Lena Vega
    Departments of Clinical Nutrition and Internal Medicine, Center for Human Nutrition of the University of Texas Southwestern Medical Center, Dallas, TX, USA The Veterans Administration North Texas Health Care System, Dallas, TX, USA Electronic address
    J Clin Lipidol 10:1414-1422.e1. 2016
    ..Both triglyceride-to-high density lipoprotein cholesterol (TG/HDL-C) and cardiorespiratory fitness (CRF) impart risk for all-cause morbidity and mortality independently of conventional risk factors...
  11. doi request reprint Secular change in cardiorespiratory fitness of men: Cooper Center Longitudinal Study
    Benjamin L Willis
    The Cooper Institute, Dallas, TX 75230, USA
    Med Sci Sports Exerc 43:2134-9. 2011
    ..During the last four decades, national guidelines for physical activity and fitness have emerged in an ongoing effort to improve health outcomes through enhanced CRF risk profiles...
  12. pmc Cardiorespiratory fitness and long-term survival in "low-risk" adults
    Carolyn E Barlow
    The Cooper Institute, University of Texas Southwestern Medical Center, Dallas, TX C E B, L F D
    J Am Heart Assoc 1:e001354. 2012
    ..Prognostic factors of long-term cardiovascular risk are needed for low-risk subjects who make up the largest percentage of the US population...
  13. doi request reprint Triglyceride-to-high-density-lipoprotein-cholesterol ratio is an index of heart disease mortality and of incidence of type 2 diabetes mellitus in men
    Gloria Lena Vega
    From the Center for Human Nutrition, University of Texas Southwestern Medical Center, the Veterans Affairs Medical Center at Dallas and The Cooper Institute, Dallas, TX
    J Investig Med 62:345-9. 2014
    ..This study examines the relationships of TG/HDL-C ratio to mortality from all causes, coronary heart disease (CHD), or cardiovascular disease (CVD)...
  14. pmc Association of cardiorespiratory fitness with left ventricular remodeling and diastolic function: the Cooper Center Longitudinal Study
    Stephanie K Brinker
    Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, Texas
    JACC Heart Fail 2:238-46. 2014
    ..This study sought to compare the cross-sectional associations between fitness and echocardiographic measures of cardiac structure and function...
  15. pmc High Cardiorespiratory Fitness Is Associated with Reduced Risk of Low Bone Density in Postmenopausal Women
    Laura F DeFina
    1 The Cooper Institute, Dallas, Texas
    J Womens Health (Larchmt) 25:1073-1080. 2016
    ..The goal of this study was to determine the association between cardiorespiratory fitness (CRF) and bone mineral density (BMD) of the femoral neck (FN) in postmenopausal women using existing Cooper Center Longitudinal Study data...
  16. doi request reprint The association between midlife cardiorespiratory fitness and later life chronic kidney disease: The Cooper Center Longitudinal Study
    Laura F DeFina
    The Cooper Institute, Dallas, TX, United States
    Prev Med 89:178-83. 2016
    ..Chronic kidney disease (CKD) is a major public health problem, particularly in older age and in those with diabetes mellitus (DM), with high comorbidity and treatment costs...
  17. doi request reprint Association of Ideal Cardiovascular Health and Long-term Healthcare Costs
    Benjamin L Willis
    The Cooper Institute, Dallas, Texas Electronic address
    Am J Prev Med 49:678-85. 2015
    ..The association between CV health and healthcare costs has not been reported; therefore, we evaluated the association between CV health profile and later-life healthcare costs...
  18. doi request reprint Effect of fitness on incident diabetes from statin use in primary prevention
    Nina B Radford
    Cooper Clinic, Dallas, TX, USA
    Atherosclerosis 239:43-9. 2015
    ..To assess the effect of cardiorespiratory fitness on the association between the initiation of statin therapy and incident diabetes...
  19. doi request reprint The Relationship Between Cardiorespiratory Fitness and Bone Mineral Density in Men: A Cross-sectional Study
    Heather M Wainstein
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX
    Mayo Clin Proc 91:726-34. 2016
    ..To determine the relationship between estimated cardiorespiratory fitness (CRF) and femoral neck (FN) bone mineral density (BMD) in men...
  20. doi request reprint Depressive symptoms and metabolic syndrome in preventive healthcare: the Cooper Center longitudinal study
    Cara East
    Soltero Cardiovascular Research Center, Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas, USA
    Metab Syndr Relat Disord 8:451-7. 2010
    ..The association among these factors in a generally healthy, active population with access to health care is not well defined...
  21. doi request reprint Psychometric evaluation of the Montreal Cognitive Assessment (MoCA) in three diverse samples
    Ira H Bernstein
    Department of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9129, USA
    Clin Neuropsychol 25:119-26. 2011
    ..Although useful in large non-clinical studies, the MoCA is best suited to detect and quantify cognitive impairment in clinical patients...
  22. doi request reprint Relationship between serum homocysteine levels and depressive symptoms: the Cooper Center Longitudinal Study
    Phillip Gu
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390 8849, USA
    J Clin Psychiatry 73:691-5. 2012
    ..To resolve conflicting findings in studies that suggest a relationship between elevated serum HCY levels and depression, we examined the relationship between HCY levels and depressive symptoms in the largest sample studied to date...
  23. pmc Association Between Sitting Time and Cardiometabolic Risk Factors After Adjustment for Cardiorespiratory Fitness, Cooper Center Longitudinal Study, 2010-2013
    Carolyn E Barlow
    The Cooper Institute, Dallas, Texas
    Prev Chronic Dis 13:E181. 2016
    ..Our study examined the association between sitting time and cardiometabolic risk factors after adjustment for cardiorespiratory fitness (CRF)...
  24. pmc Exercise outcomes in prevalent users of stimulant medications
    Arthur N Westover
    Department of Psychiatry, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA Department of Clinical Sciences, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA Electronic address
    J Psychiatr Res 64:32-9. 2015
    ..To compare users of stimulant medications with matched nonusers on exercise outcomes during a maximal treadmill exercise test...
  25. doi request reprint The relationship between asthma and self-reported anxiety in a predominantly healthy adult population
    Elan Gada
    Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas
    Ann Allergy Asthma Immunol 112:329-32. 2014
    ..However, whether a link between milder asthma and anxiety exists remains unclear...