Affiliation: The Children's Hospital of Philadelphia
- Neuroplastic Response After Radiation Therapy for Pediatric Brain Tumors: A Pilot StudyCarol L Armstrong
Neuro Oncology Section, Children s Hospital of Philadelphia, and Department of Pediatrics, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania Electronic address
Int J Radiat Oncol Biol Phys 95:991-8. 2016..This pilot study tested translational findings on phasic changes in children's memory systems that are sensitive and insensitive to toxic XRT effects to identify a possible neuroplastic effect...
- Phase measurement of cognitive impairment specific to radiotherapyCarol L Armstrong
Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 83:e319-24. 2012..The study design investigated semantic vs. perceptual and visual vs. verbal memory to determine the most disease-specific measure of RT-related changes and understanding of the neurotoxicity from RT to the brain...
- Neurocognitive problems in attention deficit disorder. Alternative concepts and evidence for impairment in inhibition of selective attentionC L Armstrong
University of Pennsylvania Medical School, Department of Neurology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Ann N Y Acad Sci 931:196-215. 2001..The data suggest that the cognitive disinhibition of ADHD is found in semantic recognition, but not in visuoperceptual recognition...
- The predictive value of longitudinal neuropsychologic assessment in the early detection of brain tumor recurrenceCarol L Armstrong
Department of Neurology, University of Pennsylvania Medical School, Philadelphia, Pennsylvania, USA
Cancer 97:649-56. 2003..The authors used the specificity of cognitive function principle to compare two models for the early detection of low-grade brain tumor recurrence prior to detection with clinically scheduled neuroimaging...
- Memory performance used to detect radiation effects on cognitive functioningC L Armstrong
Department of Neurology, University of Pennsylvania Medical School, Philadelphia, USA
Appl Neuropsychol 8:129-39. 2001..Knowledge of the specific patterns of change in cognition would guide the differential diagnosis and rehabilitation of survivors of brain tumors whose conditions are complicated by tumors with multiple treatments...
- Late cognitive and radiographic changes related to radiotherapy: initial prospective findingsC L Armstrong
Departments of Neurology, University of Pennsylvania Medical School, Children s Hospital of Philadelphia, PA 19104, USA
Neurology 59:40-8. 2002..This is a prospective, long-term study of XRT effects in adults, in which total dose and dose fraction were constrained and data related to tumor recurrence and neurologic comorbidity (e.g., hypertension) were excluded...
- Processing speed, attention, and working memory after treatment for medulloblastoma: an international, prospective, and longitudinal studyShawna L Palmer
Shawna L Palmer, Arzu Onar Thomas, Shengjie Wu, Dana Wallace, Jane Schreiber, and Amar Gajjar, St Jude Children s Research Hospital, Memphis, TN Carol Armstrong, Children s Hospital of Philadelphia, Philadelphia, PA Melanie J Bonner, Duke University Medical Center, Durham, NC Lynn Chapieski, Texas Children s Hospital, Houston, TX Michelle Swain, Royal Children s Hospital of Brisbane, Queensland Sarah Knight, Royal Children s Hospital of Melbourne, Melbourne, Victoria Robyn Boyle, Sydney Children s Hospital, Sydney, New South Wales, Australia and Donald Mabbott, The Hospital for Sick Children, Toronto, Ontario, Canada
J Clin Oncol 31:3494-500. 2013..The current study prospectively examined processing speed (PS), broad attention (BA), and working memory (WM) ability of patients diagnosed with medulloblastoma over a 5-year period...
- The impact of frontal and non-frontal brain tumor lesions on Wisconsin Card Sorting Test performanceBram Goldstein
Gynecologic Oncology Associates, Hoag Memorial Hospital, 351 Hospital Road, Suite 507, Newport Beach, CA 92663, USA
Brain Cogn 54:110-6. 2004..In addition, the left frontal group committed significantly more perseverative errors than the right frontal group. These results suggest that the WCST is sensitive to the effects of low-grade brain tumors on executive functioning...
- A critical review of the clinical effects of therapeutic irradiation damage to the brain: the roots of controversyCarol L Armstrong
Department of Neurology, University of Pennsylvania Medical School, Philadelphia, Pennsylvania 19104, USA
Neuropsychol Rev 14:65-86. 2004..Furthermore, radiation effects appear severe only in a minority of patients. Risk is related to direct and indirect effects of cancer type, concurrent clinical factors, and premorbid risk factors...
- MRI changes due to early-delayed conformal radiotherapy and postsurgical effects in patients with brain tumorsCarol L Armstrong
Department of Neurology, University of Pennsylvania Medical School, Philadelphia, PA, USA
Int J Radiat Oncol Biol Phys 63:56-63. 2005..tumor activity is difficult in brain tumor patients during the months after XRT when white matter hyperintensities sometimes emerge. We examined brain scans in XRT-treated vs. untreated patients for early-delayed post-XRT effects...
- The impact of low-grade brain tumors on verbal fluency performanceBram Goldstein
Department of Gynecologic Oncology, Hoag Memorial Hospital Presbyterian, Newport Beach, CA 92660, USA
J Clin Exp Neuropsychol 26:750-8. 2004..While we encountered semantic fluency impairments in this brain tumor population, we did not find the extensive deficits associated with the distinct or localized brain regions previously reported in the literature...
- The impact of left and right intracranial tumors on picture and word recognition memoryBram Goldstein
Division of Neurology, Children s Hospital of Philadelphia, Philadelphia, PA, USA
Brain Cogn 54:1-6. 2004..Dual coding and enhanced visual imagery may have contributed to the patient groups' similar performance on the remainder of the measures...
- Proceedings of the conference on the effects of radiotherapy on the brain and on behavior through the life span, San Juan, Puerto Rico, December 6-8, 2002Christie Seiler
The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Med Pediatr Oncol 41:460-6. 2003
- Attention in adult intracranial tumors patientsBram Goldstein
Division of Neurology, Children s Hospital of Philadelphia, PA, USA
J Clin Exp Neuropsychol 25:66-78. 2003..The fact that the DT group performed similarly to the other patient groups on the remaining attention measures suggests that these tumors are associated with especially poor attentional performance...
- RADIOTHERAPY EFFECTS ON BRAIN FUNCTIONING IN ADULTSCAROL ARMSTRONG; Fiscal Year: 2001..They will gather pilot data on the sensitivity of MTI to radiation effects in 37 cases during the early and late delayed periods. Standard brain regions, tumor sites and specific regions will be examined. ..