The University of Texas

Summary

Organization: The University of Texas
Country: USA

Top Publications

  1. pmc Activity of deferasirox in Mucorales: influences of species and exogenous iron
    Russell E Lewis
    Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Antimicrob Agents Chemother 55:411-3. 2011
  2. pmc A novel AKT3 mutation in melanoma tumours and cell lines
    M A Davies
    Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Br J Cancer 99:1265-8. 2008
  3. doi ACR Appropriateness Criteria on Hodgkin's lymphoma: favorable prognosis stage I and II
    Prajnan Das
    The Universityof Texas MD Anderson Cancer Center, Department of Radiation Oncology, Houston, TX 77030, USA
    J Am Coll Radiol 5:1054-66. 2008
  4. pmc Plasticity of pre- and postsynaptic GABAB receptor function in the paraventricular nucleus in spontaneously hypertensive rats
    De Pei Li
    Dept of Critical Care, Unit 110, The Univ of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Am J Physiol Heart Circ Physiol 295:H807-15. 2008
  5. doi Aging cebidae
    Lawrence Williams
    Michale E Keeling Center for Comparative Medicine and Research, UT MD Anderson Cancer Center, Bastrop, TX 78602, USA
    Interdiscip Top Gerontol 36:49-61. 2008
  6. ncbi Joint effects of dietary trace metals and DNA repair capacity in lung cancer risk
    Somdat Mahabir
    Department of Epidemiology, The University of Texas M D Anderson Cancer, 1155 Pressler Boulevard, CPB4 3247, Houston, TX 77030, USA
    Cancer Epidemiol Biomarkers Prev 16:2756-62. 2007
  7. pmc Implicit attitudes to smoking are associated with craving and dependence
    Andrew J Waters
    Department of Behavioral Science, The University of Texas M D Anderson Cancer Center, P O Box 30149, Unit 1330, Houston, TX 77230, USA
    Drug Alcohol Depend 91:178-86. 2007
  8. ncbi Secondary acute myelogenous leukemia in patients with retinoblastoma: is chemotherapy a factor?
    Dan S Gombos
    Section of Ophthalmology, Department of Head and Neck Surgery, MD Anderson Cancer Center, Houston, Texas 77030, USA
    Ophthalmology 114:1378-83. 2007
  9. ncbi Adrenal cortical carcinoma--review of current knowledge and treatment practices
    Alexandria T Phan
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Hematol Oncol Clin North Am 21:489-507; viii-ix. 2007
  10. ncbi Recognizing hyperviscosity syndrome in patients with Waldenstrom macroglobulinemia
    Ellen C Mullen
    University of Texas M D Anderson Cancer Center, Houston, USA
    Clin J Oncol Nurs 11:87-95. 2007

Detail Information

Publications62

  1. pmc Activity of deferasirox in Mucorales: influences of species and exogenous iron
    Russell E Lewis
    Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Antimicrob Agents Chemother 55:411-3. 2011
    ..Exogenous iron further attenuated the deferasirox susceptibility of Mucorales isolates with low MICs. Vital staining revealed damage to subapical compartments in susceptible strains...
  2. pmc A novel AKT3 mutation in melanoma tumours and cell lines
    M A Davies
    Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Br J Cancer 99:1265-8. 2008
    ..We have also identified the first known human cell lines with naturally occurring AKT E17K mutations...
  3. doi ACR Appropriateness Criteria on Hodgkin's lymphoma: favorable prognosis stage I and II
    Prajnan Das
    The Universityof Texas MD Anderson Cancer Center, Department of Radiation Oncology, Houston, TX 77030, USA
    J Am Coll Radiol 5:1054-66. 2008
    ..Representative clinical cases are presented, with treatment recommendations from an expert panel of radiation oncologists and medical oncologists...
  4. pmc Plasticity of pre- and postsynaptic GABAB receptor function in the paraventricular nucleus in spontaneously hypertensive rats
    De Pei Li
    Dept of Critical Care, Unit 110, The Univ of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Am J Physiol Heart Circ Physiol 295:H807-15. 2008
    ..Changes in both pre- and postsynaptic GABA(B) receptors in the PVN may contribute to the control of sympathetic outflow in hypertension...
  5. doi Aging cebidae
    Lawrence Williams
    Michale E Keeling Center for Comparative Medicine and Research, UT MD Anderson Cancer Center, Bastrop, TX 78602, USA
    Interdiscip Top Gerontol 36:49-61. 2008
    ..They are also prone to a condition similar to pelvic organ prolapse in aging human females. Taken all together very little is known about the reproductive function in aging New World monkeys...
  6. ncbi Joint effects of dietary trace metals and DNA repair capacity in lung cancer risk
    Somdat Mahabir
    Department of Epidemiology, The University of Texas M D Anderson Cancer, 1155 Pressler Boulevard, CPB4 3247, Houston, TX 77030, USA
    Cancer Epidemiol Biomarkers Prev 16:2756-62. 2007
    ..No significant joint associations were seen for Se or Ca and DRC. Our joint associations between Cu-DRC, Zn-DRC and Fe-DRC and lung cancer risk require confirmation in prospective studies...
  7. pmc Implicit attitudes to smoking are associated with craving and dependence
    Andrew J Waters
    Department of Behavioral Science, The University of Texas M D Anderson Cancer Center, P O Box 30149, Unit 1330, Houston, TX 77230, USA
    Drug Alcohol Depend 91:178-86. 2007
    ..The IAT effect was associated with scores on the Fagerstrom Test for Nicotine Dependence. In sum, automatic affective responses assessed with the smoking IAT are associated with measures of smoking motivation and dependence...
  8. ncbi Secondary acute myelogenous leukemia in patients with retinoblastoma: is chemotherapy a factor?
    Dan S Gombos
    Section of Ophthalmology, Department of Head and Neck Surgery, MD Anderson Cancer Center, Houston, Texas 77030, USA
    Ophthalmology 114:1378-83. 2007
    ..To describe a series of patients with secondary acute myelogenous leukemia (sAML) and retinoblastoma (RB)...
  9. ncbi Adrenal cortical carcinoma--review of current knowledge and treatment practices
    Alexandria T Phan
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Hematol Oncol Clin North Am 21:489-507; viii-ix. 2007
    ..Improved understanding of the molecular pathogenesis of this rare malignancy will lead to advancement in the available therapies that may improve this outcome...
  10. ncbi Recognizing hyperviscosity syndrome in patients with Waldenstrom macroglobulinemia
    Ellen C Mullen
    University of Texas M D Anderson Cancer Center, Houston, USA
    Clin J Oncol Nurs 11:87-95. 2007
    ..Although hyperviscosity syndrome is not one of the most common conditions, when it does occur, oncology nurses play a critical role in patients' assessment and care...
  11. ncbi Hematopoietic progenitor cell transplantation in 2007: new challenges and new opportunities for the center for international blood and marrow transplant research
    Sergio Giralt
    University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Biol Blood Marrow Transplant 13:263-4. 2007
  12. ncbi Lapatinib induces apoptosis in trastuzumab-resistant breast cancer cells: effects on insulin-like growth factor I signaling
    Rita Nahta
    Department of Breast Medical Oncology, Unit 1354, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Mol Cancer Ther 6:667-74. 2007
    ..As increased IGF-I receptor signaling has been implicated in trastuzumab resistance, our data strongly support further study of lapatinib as a potential therapeutic in breast cancers that have progressed on trastuzumab...
  13. ncbi Possible pentostatin-induced symptomatic hyponatremia
    Jeffrey J Bruno
    Division of Pharmacy, University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
    Pharmacotherapy 27:164-9. 2007
    ..Clinicians should be aware of the possible development of life-threatening symptomatic hyponatremia in patients receiving pentostatin...
  14. ncbi Impact of sentinel lymph node biopsy on the evolution of breast reconstruction
    Steven J Kronowitz
    Department of Plastic and Reconstructive Surgery, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Plast Reconstr Surg 118:1089-99. 2006
    ....
  15. doi Microvascular surgery in the previously operated and irradiated neck
    Matthew M Hanasono
    Department of Plastic Surgery, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Microsurgery 29:1-7. 2009
    ....
  16. doi A systems approach to analysis of molecular complexity in breast cancer
    Bryan T Hennessy
    Department of Systems Biology and the Kleberg Center for Molecular Markers, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 15:417-9. 2009
    ..They identify distinct copy number anomaly patterns in different breast cancer subtypes that implicate a number of genes as potential therapeutic targets and as potential markers of therapy responsiveness...
  17. doi Potential influences on mathematical difficulties in children and adolescents with neurofibromatosis, type 1
    Bartlett D Moore
    Section of Behavioral Pediatrics, Department of Pediatrics and Neuro Oncology, Division of Pediatrics, Children s Cancer Hospital, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Dev Disabil Res Rev 15:45-51. 2009
    ..Thus NF-1 exemplifies the wide ranging sources of potential influences on mathematical learning and MLD...
  18. doi Clinical findings with the first generation of thrombopoietic agents
    Saroj Vadhan-Raj
    Section of Cytokines and Supportive Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Semin Hematol 47:249-57. 2010
    ..The clinical experience with the first generation of thrombopoietic agents has provided insight into the biology and future directions for a second generation of thrombopoietic agents in various disorders of thrombocytopenia...
  19. doi The importance of nuclear import in protection of the vitamin D receptor from polyubiquitination and proteasome-mediated degradation
    Sara Peleg
    Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Cell Biochem 110:926-34. 2010
    ....
  20. pmc Rapid clonal shifts in response to kinase inhibitor therapy in chronic myelogenous leukemia are identified by quantitation mutation assays
    C Cameron Yin
    Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Cancer Sci 101:2005-10. 2010
    ..Rapid reselection of TKI-resistant clones occurs following therapy switch in CML...
  21. pmc A randomized controlled trial of acupuncture for osteoarthritis of the knee: effects of patient-provider communication
    Maria E Suarez-Almazor
    University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Arthritis Care Res (Hoboken) 62:1229-36. 2010
    ..We conducted a 3-month randomized clinical trial in patients with knee osteoarthritis to compare the efficacy of TCA with sham acupuncture and to examine the effects of acupuncturists' communication styles...
  22. doi Challenges associated with spinal opioid therapy for pain in patients with advanced cancer: a report of three cases
    Sriram Yennurajalingam
    Department of Palliative Care and Rehabilitation Medicine, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Pain Symptom Manage 39:930-5. 2010
    ....
  23. doi Among women who experience a recurrence after postmastectomy radiation therapy irradiation is not associated with more aggressive local recurrence or reduced survival
    Wendy A Woodward
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Breast Cancer Res Treat 123:597-605. 2010
    ..These data do not support the hypothesis that irradiation promotes biologically aggressive local recurrences...
  24. pmc A pilot study evaluating predictors of postoperative outcomes after major abdominal surgery: Physiological capacity compared with the ASA physical status classification system
    C E Hightower
    Department of Anesthesiology and Perioperative Medicine, The University of Texas M D Anderson Cancer Center, Houston, USA
    Br J Anaesth 104:465-71. 2010
    ....
  25. doi Influenza vaccination among individuals with cancer and their family members
    Ya Chen Tina Shih
    Department of Biostatistics, M D Anderson Cancer Center, University of Texas, Houston, 77230 1402, USA
    Am J Prev Med 38:61-9. 2010
    ..Influenza vaccination for family members of patients with cancer lowers patients' risk of influenza and related complications...
  26. doi Investigational immunotherapeutics for B-cell malignancies
    Alfonso Quintas-Cardama
    Department of Leukemia, The University of Texas M D Anderson Cancer Center, Unit 428, 1515 Holcombe Blvd, Houston, TX, 77030
    J Clin Oncol 28:884-92. 2010
    ..This review describes some of the most promising investigational immunotherapeutics for the treatment of B-cell malignancies...
  27. pmc Different changes in protein and phosphoprotein levels result from serum starvation of high-grade glioma and adenocarcinoma cell lines
    Victor A Levin
    Departments of Neuro Oncology, Bioinformatics and Computational Biology, and Blood and Marrow Transplantation, Section of Molecular Hematology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA
    J Proteome Res 9:179-91. 2010
    ..Contrawise, gliomas become resistant to apoptosis after 24 h of serum starvation and upregulate transcription activators and polyamines more so than adenocarciomas...
  28. doi Information technology facilitates cost-effectiveness analysis in developing countries: an observational study of breast cancer chemotherapy in Taiwan
    Ya Chen Tina Shih
    Section of Health Services Research, Department of Biostatistics, Division of Quantitative Sciences, The University of Texas M D Anderson Cancer Center, Houston, TX 77230 1402, USA
    Pharmacoeconomics 27:947-61. 2009
    ..e. 3 years) of CEF compared with CMF. It is possible that a future analysis will reach a different conclusion when more years of follow-up data become available...
  29. pmc Colorectal cancer prevention for low-income, sociodemographically-diverse adults in public housing: baseline findings of a randomized controlled trial
    Lorna H McNeill
    Department of Health Disparities Research, University of Texas MD Anderson Cancer Center, Houston, USA
    BMC Public Health 9:353. 2009
    ....
  30. doi Nerve-sparing prostatectomy and urinary function: a prospective analysis using validated quality-of-life measures
    E Jason Abel
    Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA
    Urology 73:1336-40. 2009
    ..To prospectively study whether urinary function and bother are directly related to neurovascular bundle preservation at radical prostatectomy using validated quality-of-life questionnaires...
  31. pmc Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia
    Guillermo Garcia-Manero
    Department of Leukemia, Box 428, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Blood 108:3271-9. 2006
    ..In summary, this combination of epigenetic therapy in leukemia was safe and active, and was associated with transient reversal of aberrant epigenetic marks...
  32. ncbi A Phase I study of escalating doses of the tyrosine kinase inhibitor semaxanib (SU5416) in combination with irinotecan in patients with advanced colorectal carcinoma
    Paulo M Hoff
    Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Jpn J Clin Oncol 36:100-3. 2006
    ..The small molecule tyrosine kinase inhibitor semaxanib (SU5416) is one of the several agents targeting the VEGF signaling pathway, and its development centered mostly in the treatment of colorectal cancer...
  33. ncbi Risk factors associated with atrial fibrillation after noncardiac thoracic surgery: analysis of 2588 patients
    Ara A Vaporciyan
    Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 445, Houston, TX 77030, USA
    J Thorac Cardiovasc Surg 127:779-86. 2004
    ..The purpose of this study was to identify risk factors associated with the onset of atrial fibrillation after thoracic surgery to allow more targeted interventions in patients with the highest risk...
  34. ncbi Management of infections in the neutropenic patient
    Kenneth V I Rolston
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Annu Rev Med 55:519-26. 2004
    ..Early diagnosis and treatment of many fungal and viral infections remains suboptimal. Infection control and prevention are important strategies, especially with the emergence of multidrug-resistant organisms...
  35. ncbi Sequential exposure of Aspergillus fumigatus to itraconazole and caspofungin: evidence of enhanced in vitro activity
    Dimitrios P Kontoyiannis
    Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas, M D Anderson Cancer Center, Houston, TX, USA
    Diagn Microbiol Infect Dis 47:415-9. 2003
    ..fumigatus to itraconazole resulted in dose-dependent enhanced effects of caspofungin and vice versa. Our finding suggests a preferential role for azole-caspofungin sequential combinations and merits further in vivo investigation...
  36. ncbi Use of deep intravenous sedation with propofol and the laryngeal mask airway during transesophageal echocardiography
    David Ferson
    Department of Anesthesiology and Cardiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    J Cardiothorac Vasc Anesth 17:443-6. 2003
    ....
  37. ncbi Nuclear transcription factor-kappaB in Hodgkin's disease
    Anas Younes
    Department of Lymphoma Myeloma, The University of Texas, M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 429 Houston, TX 77030, USA
    Leuk Lymphoma 44:929-35. 2003
    ..Numerous studies have shown that Hodgkin's disease cells exhibit constitutive active NF-kappaB. The present review examines the mechanism how NF-kappaB is activated and its relevance to Hodgkin's disease...
  38. ncbi Extracellular calcium and calcium sensing receptor function in human colon carcinomas: promotion of E-cadherin expression and suppression of beta-catenin/TCF activation
    Subhas Chakrabarty
    Department of Molecular Pathology, University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer Res 63:67-71. 2003
    ..In addition, the promotion of E-cadherin and suppression of beta-catenin/T cell factor may be an important mechanism underlying the chemopreventive action of Ca(2+) in colon cancer...
  39. ncbi Bcr: a negative regulator of the Bcr-Abl oncoprotein in leukemia
    Ralph B Arlinghaus
    Department of Molecular Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas, TX 77030, USA
    Oncogene 21:8560-7. 2002
    ..Serine 354 of Bcr plays a major role in this inhibition. In the case of Bcr(64-413), serine 354 is required for the formation of the unique Bcr structure that binds to the Abl SH2 domain...
  40. ncbi Phase II study of accelerated fractionation radiation therapy with carboplatin followed by PCV chemotherapy for the treatment of anaplastic gliomas
    V A Levin
    Department of Neuro Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Int J Radiat Oncol Biol Phys 53:58-66. 2002
    ..To conduct a Phase II one-arm study to evaluate the long-term efficacy and safety of accelerated fractionated radiotherapy combined with i.v. carboplatin for patients with previously untreated anaplastic gliomas...
  41. ncbi Multicentric mammary carcinoma: evidence of monoclonal proliferation
    Lavinia P Middleton
    Department of Pathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Cancer 94:1910-6. 2002
    ..We also compared the clinical outcomes of the patients in the current study with stage-matched and treatment-matched groups of patients with unicentric mammary carcinoma...
  42. ncbi Assessment of key elements to determine causation and risk factors in dentistry
    Rhonda F Jacob
    Department of Head and Neck Surgery, MD Anderson Cancer Center, Houston, Texas 77030, USA
    Dent Clin North Am 46:117-26. 2002
    ..Moving through the continuum from causation hypothesis to therapeutic intervention is the science of dentistry. It is the science of dentistry that will change the scope of the profession in this millennium...
  43. ncbi Use of the intubating LMA-Fastrach in 254 patients with difficult-to-manage airways
    D Z Ferson
    Department of Anesthesiology, The University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    Anesthesiology 95:1175-81. 2001
    ..In this study, the authors report their clinical experience with the intubating LMA (LMA-Fastrach; LMA North America, Inc., San Diego, CA) in 254 patients with different types of DA...
  44. ncbi Therapeutic options for acute myelogenous leukemia
    E H Estey
    Department of Leukemia, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4095, USA
    Cancer 92:1059-73. 2001
    ..General therapeutic options for patients with acute myelogenous leukemia (AML) are reviewed and specific new therapies are described...
  45. ncbi Tamoxifen's clinical applications: old and new
    A U Buzdar
    Department of Breast Medical Oncology, M D Anderson Cancer Center, Houston, TX 77037, USA
    Arch Fam Med 9:906-12. 2000
    ..Arch Fam Med. 2000;9:906-912..
  46. ncbi Chronic myeloid leukemia in a patient with acquired immune deficiency syndrome: complete cytogenetic response with imatinib mesylate: report of a case and review of the literature
    Apostolia Maria Tsimberidou
    Department of Leukemia, UT MD Anderson Cancer Center, 1515 Holcombe Boulevard, Box 428, Houston, TX 77030, USA
    Leuk Res 28:657-60. 2004
    ..It appears that there is no in vivo interaction between imatinib and highly active anti-retroviral therapy (HAART) and these drugs can be concurrently administered with safety to patients with CML and AIDS...
  47. ncbi Current developments in hormonal therapy of breast cancer
    Aman U Buzdar
    Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030 4009, USA
    Clin Breast Cancer 5:S4-5. 2004
  48. ncbi Characteristics of the anterolateral thigh flap in a Western population and its application in head and neck reconstruction
    Peirong Yu
    Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, FC 8 2000, 1400 Holcombe Boulevard, Houston 77030, USA
    Head Neck 26:759-69. 2004
    ..The purposes of this study are to classify the vascular anatomy and to assess the suitability of this flap for head and neck reconstruction in a Western population...
  49. ncbi Use of the i-STAT portable clinical analyzer in mice
    Peggy Tinkey
    Department of Veterinary Medicine and Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Lab Anim (NY) 35:45-50. 2006
    ..As shown with other species, the i-STAT results did not always agree with standard laboratory instruments; however, the i-STAT does show reliability for certain chemistry assays...
  50. ncbi Disease-free and overall survival after pathologic complete disease remission of cytologically proven inflammatory breast carcinoma axillary lymph node metastases after primary systemic chemotherapy
    Bryan T Hennessy
    Department of Breast Medical Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 106:1000-6. 2006
    ..The purpose of the current study was to determine long-term outcome in patients achieving a pCR of cytologically proven inflammatory breast carcinoma ALN metastases after primary chemotherapy...
  51. ncbi CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment
    Jan A Burger
    Department of Leukemia, Unit 428, The University of Texas M D Anderson Cancer Center, PO Box 301402, Houston, TX 77230 1402, USA
    Blood 107:1761-7. 2006
    ..As such, CXCR4 antagonists, although initially developed for treatment of AIDS, actually may become effective agents for the treatment of neoplastic disease...
  52. ncbi Factors predictive of distant metastases in patients with breast cancer who have a pathologic complete response after neoadjuvant chemotherapy
    Ana M Gonzalez-Angulo
    Department of Breast Medical Oncology, Unit 424, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    J Clin Oncol 23:7098-104. 2005
    ..To identify clinicopathological factors predictive of distant metastasis in patients who had a pathologic complete response (pCR) after neoadjuvant chemotherapy (NC)...
  53. ncbi Cognitive impairment, fatigue, and cytokine levels in patients with acute myelogenous leukemia or myelodysplastic syndrome
    Christina A Meyers
    Department of Neurooncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 104:788-93. 2005
    ..The objective of the current study was to assess the correlations between cognitive function, fatigue, quality of life, and circulating cytokine levels in patients with acute myelogenous leukemia (AML) and myelodysplastic syndrome (MDS)...
  54. ncbi Adjuvant chemotherapy in completely resected non-small-cell lung cancer
    Katherine M W Pisters
    UT M D Anderson Cancer Center, Unit 432, PO Box 301402, Houston, TX 77230 1402, USA
    J Clin Oncol 23:3270-8. 2005
    ..In view of the most recent data, postoperative platin-based chemotherapy can now be considered the standard of care for completely resected NSCLC patients with good performance status...
  55. ncbi Depressive symptoms have an independent, gradient risk for coronary heart disease incidence in a random, population-based sample
    Paul J Rowan
    The Houston Veterans Affairs Medical Center, Veterans Affairs South Central Mental Illness Research, Education, and Clinical Centers, Houston, TX, USA
    Ann Epidemiol 15:316-20. 2005
    ..Few population-based, prospective studies have tested a gradient risk for depressive symptoms on CHD incidence...
  56. ncbi Dosimetric uncertainties of three-dimensional dose reconstruction from two-dimensional data in a multi-institutional study
    Rebecca Weinberg
    Department of Radiation Oncology, The Vanderbilt Clinic, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    J Appl Clin Med Phys 5:15-28. 2004
    ..However, dosimetric accuracy will depend on image quality of the treatment planning CT data and consistency in the delineation of tumor volumes...
  57. ncbi Intensity-modulated radiotherapy: is xerostomia still prevalent?
    Mark S Chambers
    Department of Head and Neck Surgery, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030 4009, USA
    Curr Oncol Rep 7:131-6. 2005
    ....
  58. ncbi The role of mitoxantrone in the treatment of indolent lymphomas
    Fredrick Hagemeister
    The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
    Oncologist 10:150-9. 2005
    ..Because cure remains elusive in patients with indolent lymphoma, maximum prolongation of PFS with minimal toxicity and maximum preservation of quality of life should remain central goals of treatment...
  59. ncbi TAS-108: a novel steroidal antiestrogen
    Aman U Buzdar
    University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 11:906s-8s. 2005
    ..In the phase I study, there was evidence of biological antitumor activity, with stable disease noted in several patients. A phase II study is ongoing, and phase III studies are being planned with the drug...
  60. ncbi Estimating the growth rates of primary lung tumours from samples with missing measurements
    Olga Gorlova
    Department of Epidemiology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Stat Med 24:1117-34. 2005
    ..The relative error of the best estimates, as assessed by simulation, rarely exceeds 20 per cent. We found that the results of application of our estimation procedures to chest X-ray screening data agree well with the expectations...
  61. ncbi Adult glioma incidence trends in the United States, 1977-2000
    Kenneth R Hess
    Department of Biostatistics and Applied Mathematics, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 101:2293-9. 2004
    ..A more complete understanding of adult glioma incidence trends might provide indications of risk factors for gliomas and contribute to the search for improved therapies...
  62. ncbi Effect of smoking on complications in patients undergoing free TRAM flap breast reconstruction
    D W Chang
    Department of Plastic and Reconstructive Surgery, University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Plast Reconstr Surg 105:2374-80. 2000
    ..Smoking-related complications were significantly reduced when the reconstruction was delayed or when the patient stopped smoking at least 4 weeks before surgery...

Research Grants62

  1. Prediction of Pathologic Complete Response by Gene Expression Profiling in Esopha
    Jaffer A Ajani; Fiscal Year: 2010
    ..Our goal is to pave the way for a strategy in the future that will allow administration of effective therapy, improve safety, and preserve the esophagus in some patients. ..
  2. Preoperative chemotherapy for breast cancer
    Lajos Pusztai; Fiscal Year: 2007
    ..We expect that our work will lead to the development of microarray-based clinical tests to personalize chemotherapy selection for an individual with newly diagnosed breast cancer. ..
  3. Clofarabine: Cytarabine Activation for Leukemia Response
    Stefan Faderl; Fiscal Year: 2004
    ..abstract_text> ..
  4. CUTANEOUS ONCOLOGY
    Madeleine Duvic; Fiscal Year: 2004
    ..Young physicians and students who receive advanced training in the proper detection, prevention, and treatment of skin cancers will be a resource and may improve outcomes for patients of the future. ..
  5. STATISTICAL METHODS FOR COMPLEX CANCER TRIALS
    Peter Thall; Fiscal Year: 2006
    ..In order to promulgate the methods to the statistical and medical communities, user-friendly computer software for implementation will be made freely available. ..
  6. STATISTICAL METHODS FOR COMPLEX CANCER TRIALS
    Peter F Thall; Fiscal Year: 2010
    ....
  7. Morphine versus Methadone as First Line Strong Opioid for Cancer Pain
    Eduardo Bruera; Fiscal Year: 2007
    ..Relevance to Public Health: In this study, we will test if methadone is better than morphine in cancer pain control, quality of life, and is more cost-effective. ..
  8. Methylphenidate for Fatigue in Advanced Cancer Patients
    Eduardo Bruera; Fiscal Year: 2007
    ....
  9. Parenteral Hydration in Advanced Cancer Patients: A Randomized Controlled Trial
    Eduardo Bruera; Fiscal Year: 2009
    ..In this study, we will test if giving fluid through the vein will improve the symptoms, delay confusion and prolong life in patients who are no longer to drink at the end of life. ..
  10. STATISTICAL METHODS FOR COMPLEX CANCER TRIALS
    Peter Thall; Fiscal Year: 2002
    ..The aim is to provide a basis for safety monitoring in phase III trials that is part of the formal test, rather than an additional ad hoc procedure. ..
  11. Methylphenidate for Fatigue in Advanced Cancer Patients
    Eduardo Bruera; Fiscal Year: 2009
    ....
  12. Morphine versus Methadone as First Line Strong Opioid for Cancer Pain
    Eduardo Bruera; Fiscal Year: 2009
    ..Relevance to Public Health: In this study, we will test if methadone is better than morphine in cancer pain control, quality of life, and is more cost-effective. ..
  13. Parenteral Hydration in Advanced Cancer Patients: A Randomized Controlled Trial
    Eduardo Bruera; Fiscal Year: 2009
    ..In this study, we will test if giving fluid through the vein will improve the symptoms, delay confusion and prolong life in patients who are no longer to drink at the end of life. ..
  14. Molecular Epidemiology of Pancreatic Cancer
    Donghui Li; Fiscal Year: 2007
    ..Such information will be valuable for the primary prevention of this deadly disease. ..
  15. LIPOSOMAL BCL-2 ANTISENSE THERAPY FOR SOLID TUMORS
    Francisco Esteva; Fiscal Year: 2003
    ..Gabriel Lopez-Berestein (Department of Bioimmunotherapy). M. D. Anderson Cancer Center has the patients and resources necessary for Dr. Esteva to successfully complete this research project. ..
  16. Genetic Susceptibility Modifiers in Renal Cell Carcinoma
    Xifeng Wu; Fiscal Year: 2007
    ..Such individuals may then be targeted for intervention programs such as chemoprevention or dietary modification. ..
  17. GENETIC INFLUENCE ON MUTAGEN SENSITIVITY--A TWIN STUDY
    Xifeng Wu; Fiscal Year: 2004
    ..Additionally, these potential biomarkers may ultimately be used to identify individuals who should be targeted for more intense screening programs or behavior modification interventions. ..
  18. Genetic Instability & Risk for Esophageal Carcinoma
    Xifeng Wu; Fiscal Year: 2010
    ..The ability to rapidly screen individuals for risk, using minimally invasive procedures (blood samples), has immense clinical implication, such as intensive screening and chemopreventive interventions. ..
  19. Farnesyltransferase Inhibitor Therapy for Myelodysplasia
    Razelle Kurzrock; Fiscal Year: 2002
    ....
  20. Exploratory Trial of Curcumin in Pancreatic Cancer
    Razelle Kurzrock; Fiscal Year: 2005
    ..These studies should provide the foundation for the development of curcumin as an anticancer agent and may lead to a novel approach to the management of pancreatic cancer. ..
  21. Cell Cycle Controlling Genes in Adult Acute Lymphoma
    Guillermo Garcia Manero; Fiscal Year: 2005
    ..abstract_text> ..
  22. Lung Cancer Chemoradiation: Predictors of Survival
    Xifeng Wu; Fiscal Year: 2007
    ..This multivariate prognostic study could have long-term prognostic potential by allowing greater individualization of therapy, based on the genetic makeup of the patient, thereby both increasing efficacy and reducing morbidity. ..
  23. Markers of Genetic Susceptibility to Bladder Cancer
    Xifeng Wu; Fiscal Year: 2007
    ..The ability to rapidly screen individuals for risk, using minimally invasive procedures (blood samples), has immense clinical implication, such as intensive screening and chemopreventive interventions. ..
  24. Phase I study of 5-aza-2?-deoxycitidine in acute lymphocytic leukemia
    Guillermo Garcia Manero; Fiscal Year: 2007
    ..In this proposal, we plan to develop a new form of low-dose chemotherapy, decitabine, for these patients. Early results indicate that this is active and safe. ..