Cheryl Lyn Walker

Summary

Affiliation: Texas A and M Health Science Center
Country: USA

Publications

  1. ncbi Loss of p27 Associated with Risk for Endometrial Carcinoma Arising in the Setting of Obesity
    A S McCampbell
    Institute of Biosciences and Technology, Texas A and M Health Science Center, Center for Translational Cancer Research, 2121 W Holcombe Blvd, Houston, Texas 77030, USA
    Curr Mol Med 16:252-65. 2016
  2. pmc Molecular pathways: environmental estrogens activate nongenomic signaling to developmentally reprogram the epigenome
    Rebecca Lee Yean Wong
    Center for Translational Cancer Research, Institute of Biosciences and Technology, The Texas A and M University System Health Science Center, Houston, Texas 77030, USA
    Clin Cancer Res 19:3732-7. 2013
  3. pmc Environmental estrogens differentially engage the histone methyltransferase EZH2 to increase risk of uterine tumorigenesis
    K Leigh Greathouse
    Science Park Research Division, Department of Carcinogenesis, The University of Texas MD Anderson Cancer Center, Smithville, Texas, USA
    Mol Cancer Res 10:546-57. 2012
  4. pmc Developmental reprogramming of cancer susceptibility
    Cheryl Lyn Walker
    Institute of Biosciences and Technology, Texas A and M Health Science Center, 2121 W Holcombe Boulevard, Houston, TX 77030, USA
    Nat Rev Cancer 12:479-86. 2012
  5. pmc ATM functions at the peroxisome to induce pexophagy in response to ROS
    Jiangwei Zhang
    Center for Translational Cancer Research, Institute for Biosciences and Technology, Texas A and M University Health Science Center, Houston, Texas 77030, USA
    Nat Cell Biol 17:1259-69. 2015
  6. pmc A new role for ATM in selective autophagy of peroxisomes (pexophagy)
    Durga Nand Tripathi
    a Center for Translation Cancer Research, Institute of BioScience and Technology, Texas A and M University Health Science Center, Houston, TX, USA
    Autophagy 12:711-2. 2016
  7. pmc A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS
    Jiangwei Zhang
    1 Center for Translational Cancer Research, Institute for Biosciences and Technology, Texas A and M Health Science Center, Houston, Texas 77030, USA 2
    Nat Cell Biol 15:1186-96. 2013
  8. pmc Methylated α-tubulin antibodies recognize a new microtubule modification on mitotic microtubules
    In Young Park
    a Center for Precision Environmental Health, Departments of Cellular and Molecular Biology and Medicine, Baylor College of Medicine, Houston, TX, USA
    MAbs 8:1590-1597. 2016
  9. pmc Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1
    Durga N Tripathi
    Institute for Biosciences and Technology, Texas A and M Health Science Center, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 110:E2950-7. 2013
  10. doi The peroxisome as a cell signaling organelle
    Durga Nand Tripathi
    Center for Translational Cancer Research, Institute of BioScience and Technology, Texas A and M University Health Science Center, Houston, TX 77030, United States
    Curr Opin Cell Biol 39:109-12. 2016

Collaborators

  • S D Hursting
  • Kayleigh M Dodd
  • Elaine A Dunlop
  • Tej K Pandita
  • Mustafa Sahin
  • Tanya T Paull
  • Gerald N Wogan
  • J Carl Barrett
  • S Kim
  • L Zhou
  • Shuk Mei Ho
  • Durga Nand Tripathi
  • Ruhee Dere
  • Jiangwei Zhang
  • In Young Park
  • Reid T Powell
  • W Kimryn Rathmell
  • A S McCampbell
  • Ji Jing
  • Angela Alexander
  • Michael B Kastan
  • Jacqueline Tait-Mulder
  • Jinhee Kim
  • Andrew R Tee
  • Durga N Tripathi
  • Rebecca Lee Yean Wong
  • K Leigh Greathouse
  • Jennifer D Cook
  • Kristen J Verhey
  • Q Zhang
  • Thai H Ho
  • Eric Jonasch
  • K H Lu
  • R Dere
  • C Wei
  • R R Broaddus
  • Mark T Bedford
  • Ian J Davis
  • B Djordjevic
  • Catherine C Fahey
  • P T Soliman
  • M L Mittelstadt
  • Pratim Chowdhury
  • Yun Chen Chiang
  • T Lynne Blasius
  • Esteban A Terzo
  • Kathryn E Hacker
  • Darius Jonasch
  • Vijaya K Charaka
  • Raj K Pandita
  • TASNEEM BAWA-KHALFE
  • Ashley Lyn Perkins
  • Ji Hoon Lee
  • Erica Kwiatkowski
  • Alessia Di Nardo
  • Juliette M Han
  • Shengli Cai
  • Phyllis L Faust
  • Laura J Trudel
  • Rebecca D Folkerth
  • Rebecca S Slack
  • Rajdeep Chowdhury
  • Jeffrey I Everitt
  • Kevin Lin
  • Megan L Mittelstadt
  • Tia Berry
  • TIFFANY BREDFELDT
  • Kurunthachalam Kannan
  • Claudio J Conti
  • Sheng Li Cai
  • Barbara J Davis

Detail Information

Publications13

  1. ncbi Loss of p27 Associated with Risk for Endometrial Carcinoma Arising in the Setting of Obesity
    A S McCampbell
    Institute of Biosciences and Technology, Texas A and M Health Science Center, Center for Translational Cancer Research, 2121 W Holcombe Blvd, Houston, Texas 77030, USA
    Curr Mol Med 16:252-65. 2016
    ..These data suggest that p27 levels and localization may be useful as a biomarker, and possible determinant, of risk for EC arising in the setting of obesity. ..
  2. pmc Molecular pathways: environmental estrogens activate nongenomic signaling to developmentally reprogram the epigenome
    Rebecca Lee Yean Wong
    Center for Translational Cancer Research, Institute of Biosciences and Technology, The Texas A and M University System Health Science Center, Houston, Texas 77030, USA
    Clin Cancer Res 19:3732-7. 2013
    ....
  3. pmc Environmental estrogens differentially engage the histone methyltransferase EZH2 to increase risk of uterine tumorigenesis
    K Leigh Greathouse
    Science Park Research Division, Department of Carcinogenesis, The University of Texas MD Anderson Cancer Center, Smithville, Texas, USA
    Mol Cancer Res 10:546-57. 2012
    ....
  4. pmc Developmental reprogramming of cancer susceptibility
    Cheryl Lyn Walker
    Institute of Biosciences and Technology, Texas A and M Health Science Center, 2121 W Holcombe Boulevard, Houston, TX 77030, USA
    Nat Rev Cancer 12:479-86. 2012
    ..We hypothesize that this epigenetic reprogramming functions as a new type of gene-environment interaction by which environmental exposures target the epigenome to increase cancer susceptibility...
  5. pmc ATM functions at the peroxisome to induce pexophagy in response to ROS
    Jiangwei Zhang
    Center for Translational Cancer Research, Institute for Biosciences and Technology, Texas A and M University Health Science Center, Houston, Texas 77030, USA
    Nat Cell Biol 17:1259-69. 2015
    ..These data reveal an important new role for ATM in metabolism as a sensor of ROS that regulates pexophagy...
  6. pmc A new role for ATM in selective autophagy of peroxisomes (pexophagy)
    Durga Nand Tripathi
    a Center for Translation Cancer Research, Institute of BioScience and Technology, Texas A and M University Health Science Center, Houston, TX, USA
    Autophagy 12:711-2. 2016
    ....
  7. pmc A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS
    Jiangwei Zhang
    1 Center for Translational Cancer Research, Institute for Biosciences and Technology, Texas A and M Health Science Center, Houston, Texas 77030, USA 2
    Nat Cell Biol 15:1186-96. 2013
    ..These data identify a role for the TSC in responding to ROS at the peroxisome, and identify the peroxisome as a signalling organelle involved in regulation of mTORC1. ..
  8. pmc Methylated α-tubulin antibodies recognize a new microtubule modification on mitotic microtubules
    In Young Park
    a Center for Precision Environmental Health, Departments of Cellular and Molecular Biology and Medicine, Baylor College of Medicine, Houston, TX, USA
    MAbs 8:1590-1597. 2016
    ..As the first reagents that specifically recognize methylated α-tubulin, these antibodies are a valuable tool for studying this new modification of the cytoskeleton, and the function of methylated microtubules...
  9. pmc Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1
    Durga N Tripathi
    Institute for Biosciences and Technology, Texas A and M Health Science Center, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 110:E2950-7. 2013
    ..As cancer cells are particularly sensitive to nitrosative stress, these data open another path for therapies capitalizing on the ability of reactive nitrogen species to induce autophagy-mediated cell death. ..
  10. doi The peroxisome as a cell signaling organelle
    Durga Nand Tripathi
    Center for Translational Cancer Research, Institute of BioScience and Technology, Texas A and M University Health Science Center, Houston, TX 77030, United States
    Curr Opin Cell Biol 39:109-12. 2016
    ....
  11. pmc Dual Chromatin and Cytoskeletal Remodeling by SETD2
    In Young Park
    Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A and M Health Science Center, Houston, TX 77030, USA
    Cell 166:950-62. 2016
    ....
  12. pmc Interaction between genetic susceptibility and early-life environmental exposure determines tumor-suppressor-gene penetrance
    Jennifer D Cook
    Graduate School of Biomedical Sciences, University of Texas, 6655 Travis Street, Suite 300, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 102:8644-9. 2005
    ....
  13. pmc β-catenin links von Hippel-Lindau to aurora kinase A and loss of primary cilia in renal cell carcinoma
    Ruhee Dere
    Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A and M Health Science Center, Houston, Texas and
    J Am Soc Nephrol 26:553-64. 2015
    ..These data define a role for β-catenin in regulating AURKA and formation of primary cilia in the setting of VHL deficiency, opening new avenues for treatment with β-catenin inhibitors to rescue ciliogenesis in ccRCC. ..