Stephen T Talcott

Summary

Affiliation: Texas A and M University
Country: USA

Publications

  1. doi request reprint Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers
    Susanne U Mertens-Talcott
    Department of Veterinary Physiology and Pharmacology, Texas A and M University, College Station, Texas 77843, USA
    J Agric Food Chem 56:7796-802. 2008
  2. doi request reprint Cocoplum (Chrysobalanus icaco L.) anthocyanins exert anti-inflammatory activity in human colon cancer and non-malignant colon cells
    Vinicius P Venâncio
    Department of Nutrition and Food Science, Texas A and M University, College Station, Texas 77843 2254, USA and Department of Clinical Analyses, Toxicology and Food Science, University of Sao Paulo, Ribeirao Preto, São Paulo 14040 903, Brazil
    Food Funct 8:307-314. 2017
  3. doi request reprint Pyrogallol, an absorbable microbial gallotannins-metabolite and mango polyphenols (Mangifera Indica L.) suppress breast cancer ductal carcinoma in situ proliferation in vitro
    Matthew J Nemec
    Interdisciplinary Program of Toxicology, Texas A and M University, College Station, TX, USA
    Food Funct 7:3825-33. 2016
  4. doi request reprint Anti-inflammatory activity of polyphenolics from açai (Euterpe oleracea Martius) in intestinal myofibroblasts CCD-18Co cells
    Manoela Maciel Dos Santos Dias
    Department of Nutrition and Food Science, Texas A and M University, College Station, TX, USA
    Food Funct 6:3249-56. 2015
  5. doi request reprint Polyphenolics from açaí ( Euterpe oleracea Mart.) and red muscadine grape (Vitis rotundifolia ) protect human umbilical vascular Endothelial cells (HUVEC) from glucose- and lipopolysaccharide (LPS)-induced inflammation and target microRNA-126
    Giuliana D Noratto
    Department of Nutrition and Food Science, Texas A and M University, College Station, TX 77843, USA
    J Agric Food Chem 59:7999-8012. 2011
  6. doi request reprint Protective effects of standardized pomegranate (Punica granatum L.) polyphenolic extract in ultraviolet-irradiated human skin fibroblasts
    Lisbeth A Pacheco-Palencia
    Department of Nutrition and Food Science, Texas A and M University, College Station, Texas 77843, USA
    J Agric Food Chem 56:8434-41. 2008
  7. doi request reprint Flavonol-rich fractions of yaupon holly leaves (Ilex vomitoria, Aquifoliaceae) induce microRNA-146a and have anti-inflammatory and chemopreventive effects in intestinal myofibroblast CCD-18Co cells
    Giuliana D Noratto
    Department of Nutrition and Food Science, Texas A and M University, College Station, TX 77843, USA
    Fitoterapia 82:557-69. 2011
  8. doi request reprint Chemical composition, antioxidant properties, and thermal stability of a phytochemical enriched oil from Acai (Euterpe oleracea Mart.)
    Lisbeth A Pacheco-Palencia
    Department of Nutrition and Food Science, Texas A and M University, College Station, Texas 77843, USA
    J Agric Food Chem 56:4631-6. 2008
  9. pmc Comparison of anti-inflammatory mechanisms of mango (Mangifera Indica L.) and pomegranate (Punica Granatum L.) in a preclinical model of colitis
    Hyemee Kim
    Department of Nutrition and Food Science, Texas A and M University, College Station, TX, USA
    Mol Nutr Food Res 60:1912-23. 2016
  10. doi request reprint Urinary metabolites from mango (Mangifera indica L. cv. Keitt) galloyl derivatives and in vitro hydrolysis of gallotannins in physiological conditions
    Ryan C Barnes
    Department of Nutrition and Food Science, Texas A and M University, College Station, TX, USA
    Mol Nutr Food Res 60:542-50. 2016

Collaborators

  • Susanne U Mertens-Talcott
  • Roderick H Dashwood
  • Giuliana Noratto
  • Carmen Gomes
  • Carmen H Brenes
  • John A Manthey
  • Hyemee Kim
  • Nivedita Banerjee
  • Ryan C Barnes
  • David Del Pozo-Insfran
  • Lisbeth A Pacheco-Palencia
  • Matthew J Nemec
  • Kimberly A Krenek
  • Joon Hee Lee
  • Vinicius P Venâncio
  • Catherine M Pfent
  • William H Bisson
  • Alexandria B Marciante
  • Jorge A Cardona
  • Paula de Aguiar Cipriano
  • Manoela Maciel Dos Santos Dias
  • Susan S Percival
  • Armando Del Follo-Martinez
  • Gabriela Angel-Morales
  • Stephen Safe
  • Matthew J Palumbo
  • Kanjana Mahattanatawee
  • Murat O Balaban
  • Paula A Cipriano
  • Lusânia M G Antunes
  • Ivan Ivanov
  • David H Byrne
  • Bernd Meibohm
  • Erik D Hendrick
  • Kalan R Prudhomme
  • Nancy D Turner
  • Kimberly Krenek
  • Hercia Stampini Duarte Martino
  • Andrea Roque-Andrade
  • Paulo César Stringheta
  • Afonso Mota Ramos
  • Lutfiye Ekici
  • Xiangrong Li
  • Lal Hingorani
  • Francis E Putz
  • Elizabeth A Baldwin
  • Sherry T Chin
  • Angela Lounds-Singleton
  • Anne C Mallak
  • Kevin Goodner
  • Jennifer Pettit-Moore
  • Gary Luzio
  • Jodie V Johnson

Detail Information

Publications37

  1. doi request reprint Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers
    Susanne U Mertens-Talcott
    Department of Veterinary Physiology and Pharmacology, Texas A and M University, College Station, Texas 77843, USA
    J Agric Food Chem 56:7796-802. 2008
    ..Results demonstrate the absorption and antioxidant effects of anthocyanins in acai in plasma in an acute human consumption trial...
  2. doi request reprint Cocoplum (Chrysobalanus icaco L.) anthocyanins exert anti-inflammatory activity in human colon cancer and non-malignant colon cells
    Vinicius P Venâncio
    Department of Nutrition and Food Science, Texas A and M University, College Station, Texas 77843 2254, USA and Department of Clinical Analyses, Toxicology and Food Science, University of Sao Paulo, Ribeirao Preto, São Paulo 14040 903, Brazil
    Food Funct 8:307-314. 2017
    ..0 μg ml-1 GAE. These results suggest that cocoplum anthocyanins possess cancer-cytotoxic and anti-inflammatory activities in both inflamed colon and colon cancer cells...
  3. doi request reprint Pyrogallol, an absorbable microbial gallotannins-metabolite and mango polyphenols (Mangifera Indica L.) suppress breast cancer ductal carcinoma in situ proliferation in vitro
    Matthew J Nemec
    Interdisciplinary Program of Toxicology, Texas A and M University, College Station, TX, USA
    Food Funct 7:3825-33. 2016
    ..Overall, the AKT/mTOR signaling axis appears to be implicated as causal in decreased proliferation induced by diet-relevant concentrations of ML and PG. ..
  4. doi request reprint Anti-inflammatory activity of polyphenolics from açai (Euterpe oleracea Martius) in intestinal myofibroblasts CCD-18Co cells
    Manoela Maciel Dos Santos Dias
    Department of Nutrition and Food Science, Texas A and M University, College Station, TX, USA
    Food Funct 6:3249-56. 2015
    ..Results indicate the potential for açai polyphenolics in the prevention of intestinal inflammation. ..
  5. doi request reprint Polyphenolics from açaí ( Euterpe oleracea Mart.) and red muscadine grape (Vitis rotundifolia ) protect human umbilical vascular Endothelial cells (HUVEC) from glucose- and lipopolysaccharide (LPS)-induced inflammation and target microRNA-126
    Giuliana D Noratto
    Department of Nutrition and Food Science, Texas A and M University, College Station, TX 77843, USA
    J Agric Food Chem 59:7999-8012. 2011
    ..Of the screened microRNAs, only microRNA-126 expression was found to be modulated by Ac and Gp as the underlying mechanism to inhibit gene and protein expression of VCAM-1...
  6. doi request reprint Protective effects of standardized pomegranate (Punica granatum L.) polyphenolic extract in ultraviolet-irradiated human skin fibroblasts
    Lisbeth A Pacheco-Palencia
    Department of Nutrition and Food Science, Texas A and M University, College Station, Texas 77843, USA
    J Agric Food Chem 56:8434-41. 2008
    ..9 to 8.6 muM Trolox equivalents/mL). Results from this study demonstrate the protective effects of PE against UVA- and UVB-induced cell damage and the potential use of pomegranate polyphenolics in topical applications...
  7. doi request reprint Flavonol-rich fractions of yaupon holly leaves (Ilex vomitoria, Aquifoliaceae) induce microRNA-146a and have anti-inflammatory and chemopreventive effects in intestinal myofibroblast CCD-18Co cells
    Giuliana D Noratto
    Department of Nutrition and Food Science, Texas A and M University, College Station, TX 77843, USA
    Fitoterapia 82:557-69. 2011
    ..In addition, up-regulation of microRNA-146a (miR-146a) known as a negative regulator of pro-inflammatory NF-κB activation was the underlying molecular mechanism that protected CCD-18Co from inflammation...
  8. doi request reprint Chemical composition, antioxidant properties, and thermal stability of a phytochemical enriched oil from Acai (Euterpe oleracea Mart.)
    Lisbeth A Pacheco-Palencia
    Department of Nutrition and Food Science, Texas A and M University, College Station, Texas 77843, USA
    J Agric Food Chem 56:4631-6. 2008
    ..Because of its high phenolic content, the phytochemical-enriched acai oil from acai fruit offers a promising alternative to traditional tropical oils for food, supplements, and cosmetic applications...
  9. pmc Comparison of anti-inflammatory mechanisms of mango (Mangifera Indica L.) and pomegranate (Punica Granatum L.) in a preclinical model of colitis
    Hyemee Kim
    Department of Nutrition and Food Science, Texas A and M University, College Station, TX, USA
    Mol Nutr Food Res 60:1912-23. 2016
    ..This study compared tannin-rich preparations from mango (rich in gallotannins) and pomegranate (rich in ellagitannins) in the dextran sodium sulfate-induced colitis model...
  10. doi request reprint Urinary metabolites from mango (Mangifera indica L. cv. Keitt) galloyl derivatives and in vitro hydrolysis of gallotannins in physiological conditions
    Ryan C Barnes
    Department of Nutrition and Food Science, Texas A and M University, College Station, TX, USA
    Mol Nutr Food Res 60:542-50. 2016
    ..The absorption, metabolism, and excretion of mango galloyl derivatives (GD) has not yet been investigated in humans, and studies investigating repeated dosages of polyphenols are limited...
  11. doi request reprint Polyphenolics from mango (Mangifera indica L.) suppress breast cancer ductal carcinoma in situ proliferation through activation of AMPK pathway and suppression of mTOR in athymic nude mice
    Matthew J Nemec
    Interdisciplinary Program of Toxicology, Texas A and M University, College Station, TX
    J Nutr Biochem 41:12-19. 2016
    ..These results suggest that mango polyphenols and their major microbial metabolite, pyrogallol, inhibit proliferation of breast cancer cells through ROS-dependent up-regulation of AMPK and down-regulation of the AKT/mTOR pathway...
  12. doi request reprint Pomegranate polyphenolics suppressed azoxymethane-induced colorectal aberrant crypt foci and inflammation: possible role of miR-126/VCAM-1 and miR-126/PI3K/AKT/mTOR
    Nivedita Banerjee
    Interdisciplinary Program of Toxicology, Texas A and M University, College Station, TX 77843, USA
    Carcinogenesis 34:2814-22. 2013
    ..In summary, therapeutic potentials of pomegranate in colon tumorigenesis were due in part to targeting miR-126-regulated pathways, which contributes in the underlying anti-inflammatory mechanisms. ..
  13. pmc Mango polyphenolics reduce inflammation in intestinal colitis-involvement of the miR-126/PI3K/AKT/mTOR axis in vitro and in vivo
    Hyemee Kim
    Department of Nutrition and Food Science, Texas A and M University, College Station, Texas
    Mol Carcinog 56:197-207. 2017
    ..2016 Wiley Periodicals, Inc...
  14. doi request reprint Resveratrol and quercetin in combination have anticancer activity in colon cancer cells and repress oncogenic microRNA-27a
    Armando Del Follo-Martinez
    Department of Nutrition and Food Science, Texas A and M University, College Station, Texas 77843, USA
    Nutr Cancer 65:494-504. 2013
    ..This was confirmed by transfection of cells with the specific mimic for miR-27a, which partially reversed the effects of RQ. These findings are consistent with previous studies on botanical anticancer agents in colon cancer cells...
  15. doi request reprint Anticarcinogenic effects of polyphenolics from mango (Mangifera indica) varieties
    Giuliana D Noratto
    Department of Nutrition and Food Science, Texas A and M University, College Station, Texas 77843, USA
    J Agric Food Chem 58:4104-12. 2010
    ..Overall, polyphenolics from several mango varieties exerted anticancer effects, where compounds from Haden and Ataulfo mango varieties possessed superior chemopreventive activity...
  16. doi request reprint Plum polyphenols inhibit colorectal aberrant crypt foci formation in rats: potential role of the miR-143/protein kinase B/mammalian target of rapamycin axis
    Nivedita Banerjee
    Interdisciplinary Program of Toxicology, Texas A and M University, College Station, TX 77843, USA
    Nutr Res 36:1105-1113. 2016
    ..These results suggest that plum polyphenols may exhibit a chemopreventive potential against colon carcinogenesis by impacting the AKT/mTOR pathway and miR-143...
  17. doi request reprint Absorption and biological activity of phytochemical-rich extracts from açai (Euterpe oleracea Mart.) pulp and oil in vitro
    Lisbeth A Pacheco-Palencia
    Department of Nutrition and Food Science and Department of Veterinary Physiology and Pharmacology, Texas A and M University, College Station, Texas 77843, USA
    J Agric Food Chem 56:3593-600. 2008
    ..Results from this study provide further evidence for the bioactive properties of acai polyphenolics and offer new insight on their composition and cellular absorption...
  18. doi request reprint Mango polyphenolics suppressed tumor growth in breast cancer xenografts in mice: role of the PI3K/AKT pathway and associated microRNAs
    Nivedita Banerjee
    Interdisciplinary Program of Toxicology, Texas A and M University, College Station, TX, 77843, USA Department of Nutrition and Food Science, Texas A and M University, College Station, TX, 77843, USA
    Nutr Res 35:744-51. 2015
    ..In summary, mango polyphenolics have a chemotherapeutic potential against breast cancer that at least in part is mediated through the PI3K/AKT pathway and miR-126. ..
  19. doi request reprint Phytochemical composition and effects of commercial enzymes on the hydrolysis of gallic acid glycosides in mango (Mangifera indica L. cv. 'Keitt') pulp
    Kimberly A Krenek
    Department of Nutrition and Food Science, Texas A and M University, College Station, Texas 77843 2254, United States
    J Agric Food Chem 62:9515-21. 2014
    ..Fruit quality, in vivo absorption rate, and bioactivity of mango phytochemicals rely on their chemical characterization, and characterizing changes in composition is critical for a complete understanding of in vivo mechanisms. ..
  20. doi request reprint Phospholipids and terpenes modulate Caco-2 transport of açaí anthocyanins
    Jorge A Cardona
    Department of Nutrition and Food Science, Texas A and M University, College Station, TX 77843 2254, United States Department of Food Science and Technology, Pan American School of Agriculture, Zamorano University, PO Box 93, Tegucigalpa, Honduras
    Food Chem 175:267-72. 2015
    ..Results demonstrated the potential of PL and TP to increase intestinal transport of ANC, and present advancement towards the formulation of functional foods that support improved ANC absorption...
  21. doi request reprint Pre-heating and polyphenol oxidase inhibition impact on extraction of purple sweet potato anthocyanins
    Paula de Aguiar Cipriano
    Department of Nutrition and Food Science, Texas A and M University, College Station, TX 77843 2254, United States
    Food Chem 180:227-34. 2015
    ..Minimizing the impact of PPO with heat was critical to the extraction and recovery of PSP anthocyanins, suitable for food use...
  22. doi request reprint Red wine polyphenolics reduce the expression of inflammation markers in human colon-derived CCD-18Co myofibroblast cells: potential role of microRNA-126
    Gabriela Angel-Morales
    Department of Nutrition and Food Science, Texas A and M University, College Station, TX 77843, USA
    Food Funct 3:745-52. 2012
    ..04-, and 1.05-fold, for mRNA levels of NF-kB, ICAM-1, VCAM-1, and PECAM-1 respectively. This indicates the potential role of miR-126 in the anti-inflammatory properties of polyphenolics from red wine in CCD-18Co myofibroblasts cells...
  23. ncbi request reprint Fruit maturity and juice extraction influences ellagic acid derivatives and other antioxidant polyphenolics in muscadine grapes
    Joon Hee Lee
    Department of Food Science and Human Nutrition, Institute of Food and Agricultural Sciences, University of Florida, P O Box 110370, Gainesville, Florida 32611 0370, USA
    J Agric Food Chem 52:361-6. 2004
    ..Antioxidant capacity was appreciably influenced by cultivar, maturity, and location in the fruit with good correlations to soluble phenolics found in both methanolic and ethyl acetate extracts (r = 0.83 and 0.92, respectively)...
  24. ncbi request reprint Phytochemical composition and pigment stability of Açai (Euterpe oleracea Mart.)
    David Del Pozo-Insfran
    Department of Food Science and Human Nutrition, University of Florida, P O Box 110370, Gainesville, Florida 32611 0370, USA
    J Agric Food Chem 52:1539-45. 2004
    ..In the presence of ascorbic acid, acylated anthocyanin sources generally had increased color stability. Açai was recognized for its functional properties for use in food and nutraceutical products...
  25. ncbi request reprint Total antioxidant activity and fiber content of select Florida-grown tropical fruits
    Kanjana Mahattanatawee
    Citrus and Subtropical Products Laboratory, South Atlantic Area, Agricultural Research Service, United States Department of Agriculture, 600 Avenue S, Northwest, Winter Haven, Florida 33881, USA
    J Agric Food Chem 54:7355-63. 2006
    ..Preliminary descriptions are given of the phenols in red/white pitaya (dragonfruit), lychee, and mamey sapote, these fruit being thus far uncharacterized in the literature...
  26. ncbi request reprint Enhancing the retention of phytochemicals and organoleptic attributes in muscadine grape juice through a combined approach between dense phase CO2 processing and copigmentation
    David Del Pozo-Insfran
    Department of Food Science and Human Nutrition, University of Florida, P O Box 110370, Gainesville, Florida 32611 0370, USA
    J Agric Food Chem 54:6705-12. 2006
    ..DP-CO2 and copigmentation were effective strategies to reduce phytochemical and color deterioration that occurred in muscadine juice during storage without affecting their organoleptic attributes...
  27. ncbi request reprint Phytochemical stability and color retention of copigmented and processed muscadine grape juice
    Stephen T Talcott
    Department of Food Science and Human Nutrition, University of Florida, P O Box 110370, Gainesville, FL 32611 0370, USA
    J Agric Food Chem 51:957-63. 2003
    ....
  28. ncbi request reprint Induction of cell death in Caco-2 human colon carcinoma cells by ellagic acid rich fractions from muscadine grapes (Vitis rotundifolia)
    Susanne U Mertens-Talcott
    Department of Pharmaceutics, University of Florida, P O Box 110494, Gainesville, Florida 32610 0494, USA
    J Agric Food Chem 54:5336-43. 2006
    ..This study demonstrated the anticancer properties of ellagic acid rich extracts from red muscadine juice...
  29. ncbi request reprint Ellagic acid potentiates the effect of quercetin on p21waf1/cip1, p53, and MAP-kinases without affecting intracellular generation of reactive oxygen species in vitro
    Susanne U Mertens-Talcott
    Department of Food Science and Human Nutrition, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL 32611 0370, USA
    J Nutr 135:609-14. 2005
    ....
  30. ncbi request reprint Phytochemical composition and antioxidant stability of fortified yellow passion fruit (Passiflora edulis)
    Stephen T Talcott
    Department of Food Science and Human Nutrition, University of Florida, P O Box 110370, Gainesville, FL 32611 0370, USA
    J Agric Food Chem 51:935-41. 2003
    ..Physicochemical attributes and overall quality of PFJ were retained following pasteurization but were significantly impacted by degradative reactions during accelerated storage...
  31. ncbi request reprint Ellagic acid and flavonoid antioxidant content of muscadine wine and juice
    Stephen T Talcott
    Department of Food Science and Human Nutrition, University of Florida, Gainesville, Florida 32611 0370, USA
    J Agric Food Chem 50:3186-92. 2002
    ....
  32. ncbi request reprint Stability of copigmented anthocyanins and ascorbic acid in a grape juice model system
    Carmen H Brenes
    Department of Food Technology, ITESM Campus Monterrey, E Garza Sada 2501 Sur, C P 64849, Monterrey, N L, Mexico
    J Agric Food Chem 53:49-56. 2005
    ..This study indicated that the addition of anthocyanin cofactors could be used to reduce the pigment and vitamin degradation while masking detrimental color changes in anthocyanin containing products...
  33. ncbi request reprint Nitrogen fertilizer and gender effects on the secondary metabolism of yaupon, a caffeine-containing North American holly
    Matthew J Palumbo
    Department of Botany, University of Florida, Gainesville, FL 32611, USA
    Oecologia 151:1-9. 2007
    ....
  34. ncbi request reprint Microbial stability, phytochemical retention, and organoleptic attributes of dense phase CO2 processed muscadine grape juice
    David Del Pozo-Insfran
    Department of Food Science and Human Nutrition, University of Florida, P O Box 110370, Gainesville, Florida 32611 0370, USA
    J Agric Food Chem 54:5468-73. 2006
    ..DP-CO2 protected phytochemicals in muscadine juice during processing and storage without compromising microbial stability or sensory attributes over 5 weeks of storage...
  35. ncbi request reprint Neoplastic transformation of BALB/3T3 cells and cell cycle of HL-60 cells are inhibited by mango (Mangifera indica L.) juice and mango juice extracts
    Susan S Percival
    Food Science and Human Nutrition Department, University of Florida, Gainesville, FL 32611, USA
    J Nutr 136:1300-4. 2006
    ..These techniques provide valuable screening tools for health benefits derived from mango phytochemicals...
  36. ncbi request reprint Açai (Euterpe oleracea Mart.) polyphenolics in their glycoside and aglycone forms induce apoptosis of HL-60 leukemia cells
    David Del Pozo-Insfran
    Department of Food Science and Human Nutrition, University of Florida, P O Box 110370, Gainesville, Florida 32611 0370, USA
    J Agric Food Chem 54:1222-9. 2006
    ..This study demonstrated that açai offers a rich source of bioactive polyphenolics and confirmed the importance of investigating whole food systems when evaluating the potential health benefits of individual phytochemical compounds...
  37. ncbi request reprint Identification of ellagic acid conjugates and other polyphenolics in muscadine grapes by HPLC-ESI-MS
    Joon Hee Lee
    Department of Food Science and Human Nutrition, Institute of Food and Agricultural Sciences, University of Florida, P O Box 110370, Gainesville, Florida 32611, USA
    J Agric Food Chem 53:6003-10. 2005
    ..90) and total ellagic acid (r = 0.99) contents. Results of this study revealed previously unidentified ellagic acid derivatives in muscadine grapes...