Affiliation: The University of Texas School of Public Health Center For Infectious Diseases
Location: Cuernavaca, Mexico
United States trained physician, specializing in infectious diseases and experienced in international and travel/tropical medicine. Extensive experience conducting international epidemiological, translational and clinical research on infectious diseases in Mexico.
- A novel single-nucleotide polymorphism in the lactoferrin gene is associated with susceptibility to diarrhea in North American travelers to MexicoJamal A Mohamed
Division of Infectious Diseases, The University of Texas Medical School, Houston, TX 77030, USA
Clin Infect Dis 44:945-52. 2007..We investigated the impact that selected single-nucleotide polymorphisms (SNPs) in the human lactoferrin gene have on susceptibility to traveler's diarrhea...
- Patterns of illness in travelers visiting Mexico and Central America: the GeoSentinel experienceJose Flores-Figueroa
Center for Infectious Diseases, School of Public Health, Houston, Texas, USA
Clin Infect Dis 53:523-31. 2011..Mexico and Central America are important travel destinations for North American and European travelers. There is limited information on regional differences in travel related morbidity...
- Advances in the treatment of travelers' diarrheaMercedes Paredes-Paredes
University of Texas School of Public Health, 1200 Hermann Pressler Dr, Houston, TX, USA
Curr Gastroenterol Rep 13:402-7. 2011..The aim of this review is to identify the recent advances in the therapy of TD and to provide recommendations for treatment during international travel...
- Single nucleotide polymorphisms in the promoter of the gene encoding the lipopolysaccharide receptor CD14 are associated with bacterial diarrhea in US and Canadian travelers to MexicoJamal A Mohamed
Department of Internal Medicine, Division of Infectious Diseases University of Texas Medical School at Houston, Houston, TX 77030, USA
Clin Infect Dis 52:1332-41. 2011....
- Seasonality of diarrheagenic Escherichia coli pathotypes in the US students acquiring diarrhea in MexicoMercedes Paredes-Paredes
Medical School, The University of Texas at Houston, Houston, TX 77030, USA
J Travel Med 18:121-5. 2011..In Mexico, rates of diarrhea have been associated with the rainy season and increase in ambient temperature. However, the seasonality of the various diarrheagenic Escherichia coli pathotypes in travelers has not been well described...
- Campylobacter jejuni is not an important pathogen as a cause of diarrhea in US travelers to MexicoNicolas A Villa
Baylor College of Medicine, Houston, TX, USA
J Travel Med 18:56-8. 2011..Serum IgG, IgA, and IgM antibodies to Campylobacter seroconverted in only 2 of 353 participants (0.6%). These data further support that C jejuni infection is an unusual cause of travelers' diarrhea in US visitors to Mexico...
- Characterization of norovirus-associated traveler's diarrheaN Ajami
Department of Molecular Virology and Microbiology and Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
Clin Infect Dis 51:123-30. 2010..Sequences were compared using multiple sequence alignment, and phylogenetic trees were generated to evaluate the evolutionary relatedness of the viral strains associated with cases of traveler's diarrhea...
- Biochemical and genetic diversity of enterotoxigenic Escherichia coli associated with diarrhea in United States students in Cuernavaca and Guadalajara, Mexico, 2004-2007Jeannette Ouyang-Latimer
Baylor College of Medicine, 2University of Texas School of Public Health, 3University of Texas Medical School, and 4St Luke s Episcopal Hospital, Houston, Texas
J Infect Dis 201:1831-8. 2010..Molecular characterization of Escherichia coli with use of the random amplified polymorphic DNA (RAPD) assay allows the determination of clonal origin and geographic clustering...
- Pilot study of whole-blood gamma interferon response to the Vibrio cholerae toxin B subunit and resistance to enterotoxigenic Escherichia coli-associated diarrheaJose Flores
Center for Infectious Diseases, School of Public Health, University of Texas at Houston, Houston, Texas, USA
Clin Vaccine Immunol 17:879-81. 2010..Markers of the cellular immune response to ETEC LT could help in identifying individuals immune to ETEC LT, and these markers deserve additional study...
- Genetics of susceptibility to infection with enteric pathogensJose Flores
Division of Infectious Diseases, The University of Texas at Houston Medical School, Houston, Texas 77030, USA
Curr Opin Infect Dis 22:471-6. 2009..This review examines recent developments in human genetic susceptibility to enteropathogens that cause infectious diarrhea...
- A single-nucleotide polymorphism in the gene encoding osteoprotegerin, an anti-inflammatory protein produced in response to infection with diarrheagenic Escherichia coli, is associated with an increased risk of nonsecretory bacterial diarrhea in North AmeJamal A Mohamed
Division of Infectious Diseases, The University of Texas Medical School, Center for Infectious Diseases, Baylor College of Medicine, Houston, TX, USA
J Infect Dis 199:477-85. 2009....
- Enteroaggregative Escherichia coli infectionJose Flores
Division of Infectious Diseases, The University of Texas Medical School at Houston, Texas, USA
Curr Opin Gastroenterol 25:8-11. 2009..To review studies that improve the current knowledge on the epidemiology, virulence factors, detection, and chronic complications of enteroaggregative Escherichia coli (EAEC) infection...
- Epidemiology of cryptosporidiosis in North American travelers to MexicoParvathy Nair
The University of Texas Health Science Center at Houston Medical School and School of Public Health, Houston, Texas, USA
Am J Trop Med Hyg 79:210-4. 2008..Speciation by 18SrRNA sequencing showed that 13 cases were caused by C. parvum and only 1 case was caused by C. hominis. ELISA showed a sensitivity of 50% and specificity of 100% compared with PCR...
- Influence of host interleukin-10 polymorphisms on development of traveler's diarrhea due to heat-labile enterotoxin-producing Escherichia coli in travelers from the United States who are visiting MexicoJose Flores
Division of Infectious Diseases, The University of Texas Medical School, 6431 Fannin Street, Houston, TX 77030, USA
Clin Vaccine Immunol 15:1194-8. 2008..002). Travelers genetically predisposed to produce high levels of IL-10 were more likely to experience symptomatic ETEC TD...
- Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trialSarah A Frech
IOMAI Corporation, Gaithersburg, MD, USA
Lancet 371:2019-25. 2008..We investigated the rate of diarrhoea attacks, safety, and feasibility of a vaccine containing heat-labile enterotoxin (LT) from ETEC delivered to the skin by patch in travellers to Mexico and Guatemala...
- Enterotoxigenic Escherichia coli heat-labile toxin seroconversion in US travelers to MexicoJose Flores
Division of Infectious Diseases, University of Texas Medical School at Houston, Houston, TX 77030, USA
J Travel Med 15:156-61. 2008..However, the role of LT-producing ETEC (LT-ETEC) as a cause of diarrhea is controversial. We conducted a cohort study in US students traveling to Mexico to assess the ETEC-LT seroconversion rate after natural exposure...
- PCR-based assay using occult blood detection cards for detection of diarrheagenic Escherichia coli in specimens from U.S. travelers to Mexico with acute diarrheaKevin A Grimes
Division of Infectious Diseases, The University of Texas Medical School, Houston, Texas, USA
J Clin Microbiol 46:2227-30. 2008..DNA extracted from fecal cards that was used for the detection of occult blood is of use in identifying diarrheagenic E. coli...
- Seroprevalence of the enteroaggregative Escherichia coli virulence factor dispersin among USA travellers to Cuernavaca, Mexico: a pilot studyDavid B Huang
Department of Medicine, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA
J Med Microbiol 57:476-9. 2008..Further studies are needed to characterize in more detail the host clinical and immunological responses to the dispersin protein...
- A randomized, double-blind, pilot study of rifaximin 550 mg versus placebo in the prevention of travelers' diarrhea in Mexico during the dry seasonJose Flores
Center for Infectious Diseases, School of Public Health, The University of Texas Health Science Center at Houston, TX, USA
J Travel Med 18:333-6. 2011..Rifaximin has been shown to be effective in treating and preventing travelers' diarrhea (TD) during the summer season...