D Lorton

Summary

Affiliation: Sun Health Research Institute
Country: USA

Publications

  1. ncbi request reprint Bidirectional communication between the brain and the immune system: implications for physiological sleep and disorders with disrupted sleep
    Dianne Lorton
    Hoover Arthritis Research Center, Sun Health Research Institute, Sun City, AZ 85372, USA
    Neuroimmunomodulation 13:357-74. 2006
  2. ncbi request reprint Potential use of drugs that target neural-immune pathways in the treatment of rheumatoid arthritis and other autoimmune diseases
    D Lorton
    Hoover Arthritis Research Center, Sun Health Research Institute, Sun City, AZ 85351, USA
    Curr Drug Targets Inflamm Allergy 2:1-30. 2003
  3. ncbi request reprint Chemotactic-like receptors and Abeta peptide induced responses in Alzheimer's disease
    D Lorton
    Hoover Arthritis Research Center, Sun Health Research Institute, 10515 West Santa Fe Drive, Sun City, AZ 85351, USA
    Neurobiol Aging 21:463-73. 2000
  4. ncbi request reprint Proinflammatory cytokines and sickness behavior in rheumatic diseases
    D Lorton
    Arthritis Center, Sun Health Research Institute, P O Box 1278, Sun City, AZ 85372, USA
    Curr Pharm Des 14:1242-60. 2008
  5. ncbi request reprint Local application of capsaicin into the draining lymph nodes attenuates expression of adjuvant-induced arthritis
    D Lorton
    Hoover Arthritis Center, Sun Health Research Institute, Sun City, Arizona 85372, USA
    Neuroimmunomodulation 7:115-25. 2000
  6. ncbi request reprint The importance of timing of adrenergic drug delivery in relation to the induction and onset of adjuvant-induced arthritis
    Cheri L Lubahn
    Hoover Arthritis Research Center, Sun Health Research Institute, 10515 W Sante Fe Drive, Sun City, AZ 85351, USA
    Brain Behav Immun 18:563-71. 2004
  7. ncbi request reprint Aging and sympathetic modulation of immune function in Fischer 344 rats: effects of chemical sympathectomy on primary antibody response
    Denise L Bellinger
    Department of Pathology and Human Anatomy, Loma Linda University School of Medicine, 11021 Campus Street, AH 325, Loma Linda, CA 92350, United States
    J Neuroimmunol 165:21-32. 2005
  8. ncbi request reprint Age-related changes in noradrenergic sympathetic innervation of the rat spleen is strain dependent
    Denise Bellinger
    Center for Neuroimmunology, Loma Linda University School of Medicine, 11021 Campus Street, Loma Linda, CA 92352, USA
    Brain Behav Immun 16:247-61. 2002
  9. ncbi request reprint Changes in the density and distribution of sympathetic nerves in spleens from Lewis rats with adjuvant-induced arthritis suggest that an injury and sprouting response occurs
    Dianne Lorton
    Hoover Arthritis Research Center, Sun Health Research Institute, Sun City, Arizona 85351, USA
    J Comp Neurol 489:260-73. 2005
  10. pmc Sympathetic modulation of immunity: relevance to disease
    Denise L Bellinger
    Department of Pathology and Human Anatomy, Loma Linda University School of Medicine, 11021 Campus Street, Alumni Hall 325, Loma Linda, CA 92352, USA
    Cell Immunol 252:27-56. 2008

Detail Information

Publications10

  1. ncbi request reprint Bidirectional communication between the brain and the immune system: implications for physiological sleep and disorders with disrupted sleep
    Dianne Lorton
    Hoover Arthritis Research Center, Sun Health Research Institute, Sun City, AZ 85372, USA
    Neuroimmunomodulation 13:357-74. 2006
    ..This article reviews our current understanding of neuroimmune interactions in normal sleep and sleep deprivation, and the influence of these interactions on selected disorders characterized by pathological sleep...
  2. ncbi request reprint Potential use of drugs that target neural-immune pathways in the treatment of rheumatoid arthritis and other autoimmune diseases
    D Lorton
    Hoover Arthritis Research Center, Sun Health Research Institute, Sun City, AZ 85351, USA
    Curr Drug Targets Inflamm Allergy 2:1-30. 2003
    ..Furthermore, therapeutic agents targeting the neural pathways that normally regulate immune system homeostasis may prove beneficial for treating RA and other autoimmune diseases...
  3. ncbi request reprint Chemotactic-like receptors and Abeta peptide induced responses in Alzheimer's disease
    D Lorton
    Hoover Arthritis Research Center, Sun Health Research Institute, 10515 West Santa Fe Drive, Sun City, AZ 85351, USA
    Neurobiol Aging 21:463-73. 2000
    ..Given the multiple pathophysiologic roles IL-1beta may play in AD, agents that block Abeta interactions with formyl chemotactic receptors on microglia might be important antiinflammatory therapeutic targets...
  4. ncbi request reprint Proinflammatory cytokines and sickness behavior in rheumatic diseases
    D Lorton
    Arthritis Center, Sun Health Research Institute, P O Box 1278, Sun City, AZ 85372, USA
    Curr Pharm Des 14:1242-60. 2008
    ..Thus the relationship between disease pathology and psychological well being is complex...
  5. ncbi request reprint Local application of capsaicin into the draining lymph nodes attenuates expression of adjuvant-induced arthritis
    D Lorton
    Hoover Arthritis Center, Sun Health Research Institute, Sun City, Arizona 85372, USA
    Neuroimmunomodulation 7:115-25. 2000
    ..These findings support a role for small, nonmyelinated, sensory nerves that modulate immune responses in DLN in the development and progression of AA in Lewis rats...
  6. ncbi request reprint The importance of timing of adrenergic drug delivery in relation to the induction and onset of adjuvant-induced arthritis
    Cheri L Lubahn
    Hoover Arthritis Research Center, Sun Health Research Institute, 10515 W Sante Fe Drive, Sun City, AZ 85351, USA
    Brain Behav Immun 18:563-71. 2004
    ..Given current drug therapies are not effective in preventing bone destruction, these data support using adrenergic drugs as bone sparing treatments in RA...
  7. ncbi request reprint Aging and sympathetic modulation of immune function in Fischer 344 rats: effects of chemical sympathectomy on primary antibody response
    Denise L Bellinger
    Department of Pathology and Human Anatomy, Loma Linda University School of Medicine, 11021 Campus Street, AH 325, Loma Linda, CA 92350, United States
    J Neuroimmunol 165:21-32. 2005
    ..Thus, the SNS can inhibit antibody produced in response to a protein antigen in both young and old F344 rats...
  8. ncbi request reprint Age-related changes in noradrenergic sympathetic innervation of the rat spleen is strain dependent
    Denise Bellinger
    Center for Neuroimmunology, Loma Linda University School of Medicine, 11021 Campus Street, Loma Linda, CA 92352, USA
    Brain Behav Immun 16:247-61. 2002
    ..The functional significance of altered sympathetic innervation of the spleen with advancing age is discussed...
  9. ncbi request reprint Changes in the density and distribution of sympathetic nerves in spleens from Lewis rats with adjuvant-induced arthritis suggest that an injury and sprouting response occurs
    Dianne Lorton
    Hoover Arthritis Research Center, Sun Health Research Institute, Sun City, Arizona 85351, USA
    J Comp Neurol 489:260-73. 2005
    ..The redistribution of NA nerves into the red pulp may be critical in modulating immune functions that contribute to the chronic inflammatory stages of arthritis...
  10. pmc Sympathetic modulation of immunity: relevance to disease
    Denise L Bellinger
    Department of Pathology and Human Anatomy, Loma Linda University School of Medicine, 11021 Campus Street, Alumni Hall 325, Loma Linda, CA 92352, USA
    Cell Immunol 252:27-56. 2008
    ..However, a better understanding of neural-immune interactions is needed to develop strategies for treatment of immune-mediated diseases that are designed to return homeostasis and restore normal functioning neural-immune networks...