David A Stempel
- Patterns of asthma control: a 3-year analysis of patient claimsDavid A Stempel
Infomed Northwest and University of Washington, Seattle, USA
J Allergy Clin Immunol 115:935-9. 2005..The goal of asthma therapy is to maintain consistent control...
- Treatment patterns for pediatric asthma prior to and after emergency department eventsDavid A Stempel
Infomed Northwest, Bellevue, Washington, USA
Pediatr Pulmonol 40:310-5. 2005..In conclusion, this study demonstrates the dependence of children with asthma on the use of rescue medications. An ED event results in only an incremental and transient increase in ICS-containing controller treatment...
- Adherence to asthma controller medication regimensD A Stempel
Department of Pediatrics, Infomed Northwest and University of Washington, Bellevue, WA 98004, USA
Respir Med 99:1263-7. 2005....
- Treatment patterns in the months prior to and after asthma-related emergency department visitDavid A Stempel
Infomed Northwest, Seattle, WA, USA
Chest 126:75-80. 2004..This study was designed to describe the treatment patterns in the year prior to the ED event and for 2 months after the event...
- The pharmacologic management of childhood asthmaDavid A Stempel
Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98004, USA
Pediatr Clin North Am 50:609-29. 2003..Expectations should be high. Concerns about the potential for adverse effects should always be addressed proactively and should be balanced with the potential of adverse events from the disease...
- Resource utilization with fluticasone propionate and salmeterol in a single inhaler compared with other controller therapies in children with asthmaDavid A Stempel
Infomed NW and University of Washington, Seattle, WA, USA
Curr Med Res Opin 22:463-70. 2006....
- The economic impact of children dispensed asthma medications without an asthma diagnosisDavid A Stempel
Infomed Northwest Bellevue and University of Washington, Bellevue, Washington 98004, USA
J Pediatr 148:819-23. 2006..To compare the resource utilization and healthcare costs of children with a diagnosis of asthma, children dispensed asthma medications but without a diagnosis of asthma, and control children...
- The use of rhinitis medications in children receiving initial controller therapy for asthmaDavid A Stempel
Infomed Northwest Bellevue, WA 98004, USA
Curr Med Res Opin 22:2279-85. 2006..Due to common features of asthma and allergic rhinitis, a single therapeutic approach to treating both of these conditions has been proposed...
- Comparative efficacy and cost of asthma care in children with asthma treated with fluticasone propionate and montelukastDavid A Stempel
Infomed Northwest, Bellevue, WA, USA
J Pediatr 150:162-7. 2007..To assess the comparative efficacy of fluticasone propionate (FP) and montelukast (MON), using administrative claims for pediatric asthma in a clinical setting...
- The risk of hospitalization in patients with asthma switched from an inhaled corticosteroid to a leukotriene receptor antagonistDavid A Stempel
University of Washington, Seattle, WA 98004, USA
J Allergy Clin Immunol 110:39-41. 2002..Considered in aggregate, the data support the conclusion that leukotriene modifiers should not be substituted for inhaled corticosteroids as a single-controller therapy for asthma...
- Inhaled corticosteroids plus salmeterol or montelukast: effects on resource utilization and costsDavid A Stempel
Virginia Mason Clinic, Seattle, WA 98101, USA
J Allergy Clin Immunol 109:433-9. 2002..Observational research from real-world clinical practice is needed to confirm these results...
- Approaching value in asthma management: the need to integrate clinical and economic research with the basic scienceDavid A Stempel
Virginia Mason Medical Center, 1100 Ninth Avenue, Seattle, WA 98101, USA
J Allergy Clin Immunol 109:S503-10. 2002..Taken together, the results of such analyses form a foundation for providing effective, safe, and cost-efficient care through the practice of evidence-based medicine...
- The cost of treating allergic rhinitisDavid A Stempel
Virginia Mason Clinic, Virginia Mason Medical Center, 1100 Ninth Avenue, Seattle, WA 98004, USA
Curr Allergy Asthma Rep 2:223-30. 2002..INCS have lower average wholesale prices as a class than the NSAH. Since the INCS are the dominant medication in efficacy studies and cost less, cost-effectiveness studies always favor intranasal corticosteroids...
- Single-inhaler combination therapy for asthma: a review of cost effectivenessManabu Akazawa
Department of Health Policy and Administration, School of Public Health, University of North Carolina at Chapel Hill, North Carolina, USA
Pharmacoeconomics 24:971-88. 2006..Further considerations for measuring long-term outcomes and dose-response relationships might be required to provide further evidence on the cost effectiveness of combination therapy with ICS plus LABA...
- Asthma-related exacerbations, therapy switching, and therapy discontinuation: a comparison of 3 commonly used controller regimensRichard D O'Connor
Sharp Rees Stealy Medical Group, San Diego, California, USA
Ann Allergy Asthma Immunol 95:535-40. 2005..Asthma control is the goal of therapeutic interventions. In observational studies, the use of short-acting beta-agonists (SABAs) is a surrogate for symptoms and emergency department or hospital events for exacerbations...
- The status of asthma control and asthma prescribing practices in the United States: results of a large prospective asthma control survey of primary care practicesB Gwen Carlton
J Asthma 42:529-35. 2005..As a result of the assessment of the patients' level of asthma control during the office visit, physicians changed their patterns of prescribing controller therapy in patients with uncontrolled asthma...
- Effects of fluticasone propionate/salmeterol combination on asthma-related health care resource utilization and costs and adherence in children and adults with asthmaThomas E Delea
Policy Analysis Inc, Brookline, Massachusetts 02445, USA
Clin Ther 30:560-71. 2008....
- The myth of mild asthmaDavid A Stempel
Ann Allergy Asthma Immunol 89:340-3. 2002
- Study design is a major determinant of whether equivalence or superiority is demonstratedStuart W Stoloff
J Allergy Clin Immunol 111:1413; author reply 1413-4. 2003
- Improved refill persistence with fluticasone propionate and salmeterol in a single inhaler compared with other controller therapiesStuart W Stoloff
University of Nevada School of Medicine, Reno, Nev, USA
J Allergy Clin Immunol 113:245-51. 2004..Improved adherence to inhaled corticosteroids (ICSs) has also been associated with decreased asthma-associated morbidity and mortality...
- Exhaled nitric oxideDavid A Stempel
Ann Allergy Asthma Immunol 92:381; author reply 381-2. 2004
- The utility of the Health Plan Employer Data and Information Set (HEDIS) asthma measure to predict asthma-related outcomesWilliam E Berger
American College of Allergy, Asthma, and Immunology, Mission Viejo, California, USA
Ann Allergy Asthma Immunol 93:538-45. 2004..The Health Plan Employer Data and Information Set (HEDIS) measures are used extensively to measure quality of care...
- September epidemic of asthma exacerbations in children: a manifestation of persistent or episodic disease?David A Stempel
J Allergy Clin Immunol 115:230-2. 2005
- Rates and characteristics of intensive care unit admissions and intubations among asthma-related hospitalizationsTrudy B Pendergraft
GlaxoSmithKline, Research Triangle Park, North Carolina 27709, USA
Ann Allergy Asthma Immunol 93:29-35. 2004..A life-threatening attack of asthma that leads to intensive care unit (ICU) admission, intubation, or both identifies patients at high risk of subsequent morbidity and mortality and represents a major cost burden...
- ForewordHomer A Boushey
Department of Allergy and Immunology, Asthma Clinical Research Center, University of California San Francisco, 515 Parnassus Avenue, Room M192, San Francisco, CA 94143, USA
J Allergy Clin Immunol 109:S479-81. 2002
- Asthma: addressing consistency in results from basic science, clinical trials, and observational experienceJoseph Spahn
National Jewish Medical and Research Center, University of Colorado, School of Medicine, Denver, CO, USA
J Allergy Clin Immunol 109:S490-502. 2002..These analyses have confirmed that initial treatment with inhaled corticosteroids and combined treatment with inhaled corticosteroids and long-acting bronchodilators are the most effective stepwise approaches to the treatment of asthma...
- Assessing the impact of asthma guideline implementationDavid A Stempel
Chest 130:5-6. 2006
- Assessing the economic burden of asthmaDavid A Stempel
J Allergy Clin Immunol 111:1203-4. 2003
- Seasonal variation in asthma-related hospital and intensive care unit admissionsTrudy B Pendergraft
GlaxoSmithKline, RTP, North Carolina 27709, USA
J Asthma 42:265-71. 2005..These findings suggest a need for year-round vigilance and improved compliance with asthma therapy, especially during the summer when asthma attacks are perceived to be infrequent...
- Assessment of asthma control in a general population of asthmaticsMichael Lenoir
Associate Clinical Professor, Pediatrics University of California, San Francisco, Oakland, CA, USA
Curr Med Res Opin 22:17-22. 2006..Asthma control is typically assessed by review of symptoms and measurement of airflow obstruction by clinic spirometry or outpatient peak flow. Recently the role of questionnaires to assess asthma control has been discussed...
- Defining the responder in asthma therapyDavid A Stempel
J Allergy Clin Immunol 115:466-9. 2005