Affiliation: State University of New York
- Protein array characterization of bioactive proteins secreted by immortalized human corneal epithelium in response to pseudomonas constituentsRobert Sack
Department of Biological Sciences, SUNY Optometry, New York, New York 10036, USA
Curr Eye Res 34:92-8. 2009..To use protein arrays to delineate the spectrum of angiogenic bioactive protein modulators that might be secreted and up-regulated by the corneal epithelium in response to killed bacterial products...
- Membrane array characterization of 80 chemokines, cytokines, and growth factors in open- and closed-eye tears: angiogenin and other defense system constituentsRobert A Sack
SUNY Optometry, New York, New York, USA
Invest Ophthalmol Vis Sci 46:1228-38. 2005..To adapt membrane-bound antibody array (MA) technology to characterize the distribution of a wide range of bioactive trace proteins in reflex (RTF) and open-eye (OTF) and closed-eye (CTF) tear samples...
- Antibody array characterization of inflammatory mediators in allergic and normal tears in the open and closed eye environmentsRobert Sack
SUNY College of Optometry, 33 West 42nd Street, New York, NY 10036, USA
Exp Eye Res 85:528-38. 2007..Other than a modest increase in IL-8, no change could be observed in the profile of OTF after induction of an acute allergic reaction...
- Profile of lipid and protein autacoids in diabetic vitreous correlates with the progression of diabetic retinopathyMichal Laniado Schwartzman
Department of Pharmacology, New York Medical College, Valhalla, New York, USA
Diabetes 59:1780-8. 2010..This study was aimed at obtaining a profile of lipids and proteins with a paracrine function in normal and diabetic vitreous and exploring whether the profile correlates with retinal pathology...
- Tear turnover and immune and inflammatory processes in the open-eye and closed-eye environments: relationship to extended wear contact lens useRobert A Sack
SUNY College of Optometry, Manhattan, NY 10036, USA
Eye Contact Lens 29:S80-2; discussion S83-4, S192-4. 2003
- Is the cystatin-like domain of TSL functionally active in external ocular infections and during the normal diurnal cycle?Robert A Sack
State University of New York State College of Optometry, 33 West 42nd Street at Bryant Park, Manhattan, NY 10036, USA
Exp Eye Res 78:371-8. 2004..To test whether the cystatin-like functional domain in tear specific lipocalin (TSL) is functionally active in tears during the normal diurnal cycle and during external ocular infections...
- AsialoGM1-mediated IL-8 release by human corneal epithelial cells requires coexpression of TLR5Jojo W Du
Department of Biological Sciences, College of Optometry, State University of New York, 33 West 42nd Street, New York City, NY 10036, USA
Invest Ophthalmol Vis Sci 47:4810-8. 2006....
- Changes in the diurnal pattern of the distribution of gelatinases and associated proteins in normal and pathological tear fluids: evidence that the PMN cell is a major source of MMP activity in tear fluidRobert A Sack
SUNY Optometry, New York, New York, USA
Adv Exp Med Biol 506:539-45. 2002
- Interaction of Pseudomonas aeruginosa with human tear fluid componentsNancy A McNamara
Morton D Sarver Laboratory for Cornea and Contact Lens Research, School of Optometry, University of California, Berkeley, California, USA
Curr Eye Res 30:517-25. 2005..In this study, we assessed the effect of eye closure and the role of sialoglycoprotein (SG) in tears on bacterial binding and invasion...
- Tear glucose dynamics in diabetes mellitusJennifer D Lane
CIBA Vision Corporation, Duluth, GA, USA
Curr Eye Res 31:895-901. 2006..Although it is possible to determine the diabetic status of a subject using tear glucose values alone, in the clinical setting this may not prove to be practical due to technical limitations...
- Surfactant protein D is present in human tear fluid and the cornea and inhibits epithelial cell invasion by Pseudomonas aeruginosaMinjian Ni
School of Optometry, University of California, Berkeley, CA 94720 2020
Infect Immun 73:2147-56. 2005..aeruginosa invasion. Whether SP-D plays other roles in the regulation of other innate or adaptive immune responses at the ocular surface, as it does in the airways, remains to be explored...