Ruel E McKnight

Summary

Affiliation: State University of New York
Country: USA

Publications

  1. ncbi request reprint Binding of a homologous series of anthraquinones to DNA
    Ruel E McKnight
    Department of Chemistry, Georgia State University, Atlanta, GA 30303, USA
    Bioorg Med Chem Lett 14:401-4. 2004
  2. ncbi request reprint Synthesis of analogues of a flexible thiopyrylium photosensitizer for purging blood-borne pathogens and binding mode and affinity studies of their complexes with DNA
    Ruel E McKnight
    Department of Chemistry, State University of New York at Geneseo, 1 College Circle, Geneseo, NY 14454, USA
    Bioorg Med Chem 15:4406-18. 2007
  3. doi request reprint Temperature dependence of Congo red binding to amyloid β12-28
    Ruel E McKnight
    Department of Chemistry, State University of New York, College at Geneseo, Geneseo, NY, 14454, USA
    Eur Biophys J 42:495-501. 2013
  4. ncbi request reprint Binding mode and affinity studies of DNA-binding agents using topoisomerase I DNA unwinding assay
    Ruel E McKnight
    Department of Chemistry, State University of New York at Geneseo, 1 College Circle, Geneseo, NY 14454, USA
    Bioorg Med Chem Lett 17:1013-7. 2007
  5. doi request reprint Substituent control of DNA binding modes in a series of chalcogenoxanthylium photosensitizers as determined by isothermal titration calorimetry and topoisomerase I DNA unwinding assay
    Ruel E McKnight
    Department of Chemistry, State University of New York at Geneseo, 1 College Circle, Geneseo, NY 14454, USA
    Bioorg Med Chem 16:10221-7. 2008
  6. doi request reprint Substituent effect on the preferred DNA binding mode and affinity of a homologous series of naphthalene diimides
    Ruel E McKnight
    Department of Chemistry, State University of New York at Geneseo, 1 College Circle, Geneseo, NY 14454, USA
    Bioorg Med Chem Lett 21:4288-91. 2011

Detail Information

Publications6

  1. ncbi request reprint Binding of a homologous series of anthraquinones to DNA
    Ruel E McKnight
    Department of Chemistry, Georgia State University, Atlanta, GA 30303, USA
    Bioorg Med Chem Lett 14:401-4. 2004
    ..These compounds bind to an AT-rich hairpin with slightly higher affinity than to a GC-rich hairpin. The binding constants decrease as the length of the side chain increases...
  2. ncbi request reprint Synthesis of analogues of a flexible thiopyrylium photosensitizer for purging blood-borne pathogens and binding mode and affinity studies of their complexes with DNA
    Ruel E McKnight
    Department of Chemistry, State University of New York at Geneseo, 1 College Circle, Geneseo, NY 14454, USA
    Bioorg Med Chem 15:4406-18. 2007
    ..The dyes were found to show mixed binding modes...
  3. doi request reprint Temperature dependence of Congo red binding to amyloid β12-28
    Ruel E McKnight
    Department of Chemistry, State University of New York, College at Geneseo, Geneseo, NY, 14454, USA
    Eur Biophys J 42:495-501. 2013
    ..Only CR disaggregation was observed at 35 °C. These results may provide further insights into the ability of CR to inhibit Aβ toxicity in neurodegenerative diseases...
  4. ncbi request reprint Binding mode and affinity studies of DNA-binding agents using topoisomerase I DNA unwinding assay
    Ruel E McKnight
    Department of Chemistry, State University of New York at Geneseo, 1 College Circle, Geneseo, NY 14454, USA
    Bioorg Med Chem Lett 17:1013-7. 2007
    ..The assay was also used to investigate the mode of binding adopted by several known DNA-binding agents, including SYBR Green and PicoGreen. Some of the compounds exhibited unexpected binding modes...
  5. doi request reprint Substituent control of DNA binding modes in a series of chalcogenoxanthylium photosensitizers as determined by isothermal titration calorimetry and topoisomerase I DNA unwinding assay
    Ruel E McKnight
    Department of Chemistry, State University of New York at Geneseo, 1 College Circle, Geneseo, NY 14454, USA
    Bioorg Med Chem 16:10221-7. 2008
    ..The chalcogen atom appeared to have little influence on binding mode...
  6. doi request reprint Substituent effect on the preferred DNA binding mode and affinity of a homologous series of naphthalene diimides
    Ruel E McKnight
    Department of Chemistry, State University of New York at Geneseo, 1 College Circle, Geneseo, NY 14454, USA
    Bioorg Med Chem Lett 21:4288-91. 2011
    ....