Jun Seita

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc Gene Expression Commons: an open platform for absolute gene expression profiling
    Jun Seita
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS ONE 7:e40321. 2012
  2. pmc Hematopoietic stem cell: self-renewal versus differentiation
    Jun Seita
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Wiley Interdiscip Rev Syst Biol Med 2:640-53. 2010
  3. pmc MiDReG: a method of mining developmentally regulated genes using Boolean implications
    Debashis Sahoo
    Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 107:5732-7. 2010
  4. ncbi request reprint Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging
    Derrick J Rossi
    Department of Pathology, Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
    Cell Cycle 6:2371-6. 2007
  5. pmc Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development
    Matthew A Inlay
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
    Genes Dev 23:2376-81. 2009
  6. pmc Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche
    James Y Chen
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
    Nature 530:223-7. 2016
  7. pmc Identification of the earliest natural killer cell-committed progenitor in murine bone marrow
    John W Fathman
    Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Blood 118:5439-47. 2011
  8. pmc Identification of multipotent progenitors that emerge prior to hematopoietic stem cells in embryonic development
    Matthew A Inlay
    Institute for Stem Cell Biology and Regenerative Medicine ISCBRM, Stanford University, Stanford, CA 94305, USA
    Stem Cell Reports 2:457-72. 2014
  9. pmc Do pluripotent stem cells exist in adult mice as very small embryonic stem cells?
    Masanori Miyanishi
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Stem Cell Reports 1:198-208. 2013
  10. pmc Upregulation of CD11A on hematopoietic stem cells denotes the loss of long-term reconstitution potential
    John W Fathman
    Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA Electronic address
    Stem Cell Reports 3:707-15. 2014

Detail Information

Publications17

  1. pmc Gene Expression Commons: an open platform for absolute gene expression profiling
    Jun Seita
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS ONE 7:e40321. 2012
    ....
  2. pmc Hematopoietic stem cell: self-renewal versus differentiation
    Jun Seita
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Wiley Interdiscip Rev Syst Biol Med 2:640-53. 2010
    ....
  3. pmc MiDReG: a method of mining developmentally regulated genes using Boolean implications
    Debashis Sahoo
    Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 107:5732-7. 2010
    ..These data demonstrate the power of MiDReG in predicting functionally important intermediate genes in a given developmental pathway that is defined by a mutually exclusive gene expression pattern...
  4. ncbi request reprint Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging
    Derrick J Rossi
    Department of Pathology, Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
    Cell Cycle 6:2371-6. 2007
    ..Moreover, the cytoprotection afforded by stem cell quiescence in stress-free, steady-state conditions suggests a mechanism through which potentially dangerous lesions can accumulate in the stem cell pool with age...
  5. pmc Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development
    Matthew A Inlay
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
    Genes Dev 23:2376-81. 2009
    ....
  6. pmc Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche
    James Y Chen
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
    Nature 530:223-7. 2016
    ..Finally, by in situ imaging of mouse bone marrow, we show that >94% of LT-HSCs (Hoxb5(+)) are directly attached to VE-cadherin(+) cells, implicating the perivascular space as a near-homogenous location of LT-HSCs...
  7. pmc Identification of the earliest natural killer cell-committed progenitor in murine bone marrow
    John W Fathman
    Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Blood 118:5439-47. 2011
    ..Taken together, our data provide a high-resolution in vivo analysis of the earliest steps of NK cell commitment and maturation...
  8. pmc Identification of multipotent progenitors that emerge prior to hematopoietic stem cells in embryonic development
    Matthew A Inlay
    Institute for Stem Cell Biology and Regenerative Medicine ISCBRM, Stanford University, Stanford, CA 94305, USA
    Stem Cell Reports 2:457-72. 2014
    ..These experiments indicate that multipotent cells appear in concert within both the YS and AGM and strongly implicate YS-derived progenitors as contributors to definitive hematopoiesis. ..
  9. pmc Do pluripotent stem cells exist in adult mice as very small embryonic stem cells?
    Masanori Miyanishi
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Stem Cell Reports 1:198-208. 2013
    ..These results provide a failure to confirm the existence of pluripotent VSELs. ..
  10. pmc Upregulation of CD11A on hematopoietic stem cells denotes the loss of long-term reconstitution potential
    John W Fathman
    Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA Electronic address
    Stem Cell Reports 3:707-15. 2014
    ..We propose that CD11A(+)Lin-KIT(+)SCA-1(+)CD150(+)CD34- cells are multipotent progenitors and CD11A-Lin-KIT(+)SCA-1(+)CD150(+)CD34- cells are true HSCs...
  11. pmc Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells
    Charles K F Chan
    Department of Surgery, H3680, Stanford University School of Medicine, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 110:12643-8. 2013
    ....
  12. pmc Prospective isolation of human erythroid lineage-committed progenitors
    Yasuo Mori
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305 Ludwig Center for Cancer Stem Cell Biology and Medicine at Stanford University, Stanford, CA 94305
    Proc Natl Acad Sci U S A 112:9638-43. 2015
    ..These previously unclassified populations may facilitate further understanding of the molecular mechanisms governing human erythroid development and serve as potential therapeutic targets in disorders of the erythroid lineage. ..
  13. pmc Identification and specification of the mouse skeletal stem cell
    Charles K F Chan
    Department of Surgery, Stanford University, 450 Serra Mall, Palo Alto, CA 94305, USA Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, 450 Serra Mall, Palo Alto, CA 94305, USA Electronic address
    Cell 160:285-98. 2015
    ....
  14. pmc Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells
    Micha Drukker
    Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California, USA
    Nat Biotechnol 30:531-42. 2012
    ..These markers and progenitors provide tools for purifying human tissue-regenerating progenitors and for studying the commitment of pluripotent stem cells to lineage progenitors...
  15. pmc Discriminating cellular heterogeneity using microwell-based RNA cytometry
    Ivan K Dimov
    1 Biomolecular Nanotechnology Center, Berkeley Sensor and Actuator Center, Department of Bioengineering, University of California, Berkeley, California 94720, USA 2 Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
    Nat Commun 5:3451. 2014
    ..We also show that changes in expression of genes such as Birc6 during ageing can be attributed to the shift of relative portions of cells in the high-expressing subgroup versus low-expressing subgroup. ..
  16. pmc Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response
    Diane Tseng
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University Medical Center, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 110:11103-8. 2013
    ..This response protected animals from tumor challenge. We conclude that anti-CD47 antibody treatment not only enables macrophage phagocytosis of cancer but also can initiate an antitumor cytotoxic T-cell immune response. ..
  17. ncbi request reprint Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
    Derrick J Rossi
    Department of Pathology, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
    Nature 447:725-9. 2007
    ..These data are consistent with DNA damage accrual being a physiological mechanism of stem cell ageing that may contribute to the diminished capacity of aged tissues to return to homeostasis after exposure to acute stress or injury...