Eric J Rulifson
Affiliation: Stanford University
- Ablation of insulin-producing neurons in flies: growth and diabetic phenotypesEric J Rulifson
Department of Developmental Biology, Beckman Center B300, Stanford University, Stanford, CA 94305 5329, USA
Science 296:1118-20. 2002..Interestingly, the phenotype of flies lacking IPCs includes certain features of diabetes mellitus...
- Conserved mechanisms of glucose sensing and regulation by Drosophila corpora cardiaca cellsSeung K Kim
Department of Developmental Biology, Stanford University School of Medicine, Beckman Center B300, Stanford, California 94305 5329, USA
Nature 431:316-20. 2004..Thus, Drosophila CC cells are crucial regulators of glucose homeostasis and they use glucose-sensing and response mechanisms similar to islet cells...
- The origin of islet-like cells in Drosophila identifies parallels to the vertebrate endocrine axisShu Wang
Wistar Institute, Room 358, 3601 Spruce Street, Philadelphia, PA 19104, USA
Proc Natl Acad Sci U S A 104:19873-8. 2007..This ontogenic-molecular concordance suggests that a rudimentary brain endocrine axis was present in the common ancestor of humans and flies, where it orchestrated the islet-like endocrine functions of insulin and glucagon biology...