KIMBERLY I MATULEF
Affiliation: Stanford University
- Cyclic nucleotide-gated ion channelsKimberly Matulef
Department of Molecular and Cellular Physiology, Stanford University, Stanford, California 94305, USA
Annu Rev Cell Dev Biol 19:23-44. 2003..From these studies, a picture is beginning to emerge for how the binding of cyclic nucleotide is transduced into the opening of the pore and how this allosteric transition is modulated by various physiological effectors...
- Side-dependent inhibition of a prokaryotic ClC by DIDSKimberly Matulef
Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, California 94305, USA
Biophys J 89:1721-30. 2005..The side-dependent nature of DIDS inhibition will be useful for generating "functionally oriented" preparations of ClC-ec1, in which DIDS is used to silence transporters in one orientation but not the other...
- Molecular Mechanisms of CIC TransporterKimberly Matulef; Fiscal Year: 2006..In Specific Aim 3, I will determine the rates of efflux and exchange in oriented vesicles in order to determine the rate limiting step(s) in coupled transport. ..