Michael Z Lin

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. pmc TimeSTAMP tagging of newly synthesized proteins
    Michael Z Lin
    Department of Pediatrics and Programs in Gene Therapy and Molecular Imaging, Stanford University, Stanford, California, USA
    Curr Protoc Protein Sci . 2010
  2. doi request reprint Beyond the rainbow: new fluorescent proteins brighten the infrared scene
    Michael Z Lin
    Departments of Pediatrics and Bioengineering, Stanford University, Stanford, California, USA
    Nat Methods 8:726-8. 2011
  3. pmc Improving FRET dynamic range with bright green and red fluorescent proteins
    Amy J Lam
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nat Methods 9:1005-12. 2012
  4. doi request reprint Cell-Type-Specific Optical Recording of Membrane Voltage Dynamics in Freely Moving Mice
    Jesse D Marshall
    James H Clark Center for Biomedical Engineering and Sciences, Stanford University, Stanford, CA 94305, USA CNC Program, Stanford University, Stanford, CA 94305, USA Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA
    Cell 167:1650-1662.e15. 2016
  5. doi request reprint Fluorescent indicators for simultaneous reporting of all four cell cycle phases
    Bryce T Bajar
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nat Methods 13:993-996. 2016
  6. pmc Tunable and reversible drug control of protein production via a self-excising degron
    Hokyung K Chung
    Department of Biology, Stanford University, Stanford, California, USA
    Nat Chem Biol 11:713-20. 2015
  7. doi request reprint Subcellular Imaging of Voltage and Calcium Signals Reveals Neural Processing In Vivo
    Helen H Yang
    Department of Neurobiology, Stanford University, Stanford, CA 94305, USA
    Cell 166:245-57. 2016
  8. doi request reprint Genetically encoded indicators of neuronal activity
    Michael Z Lin
    Department of Neurobiology, Stanford University, Stanford, California, USA
    Nat Neurosci 19:1142-53. 2016
  9. pmc Improving brightness and photostability of green and red fluorescent proteins for live cell imaging and FRET reporting
    Bryce T Bajar
    Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA
    Sci Rep 6:20889. 2016
  10. pmc Designs and sensing mechanisms of genetically encoded fluorescent voltage indicators
    François St-Pierre
    Department of Pediatrics, Stanford University, Stanford, CA, USA Department of Bioengineering, Stanford University, Stanford, CA, USA
    Curr Opin Chem Biol 27:31-8. 2015

Collaborators

  • Michael W Davidson
  • Xiaokun Shu
  • François St-Pierre
  • Bryce T Bajar
  • Jesse D Marshall
  • Amy J Lam
  • Mark J Schnitzer
  • Yiyang Gong
  • Xin X Zhou
  • Roger Y Tsien
  • Jun Chu
  • Helen H Yang
  • Conor L Jacobs
  • Hokyung K Chung
  • Jin Yang
  • Margaret T Butko
  • Xiaozhe Ding
  • Yanping Zhang
  • Namdoo Kim
  • Ryan K Badiee
  • Barney F Cruz
  • Thomas R Clandinin
  • Benjamin B Kim
  • Elizabeth S Howe
  • Xulu Sun
  • Mingyu Chung
  • Tobias Meyer
  • Jin Zhong Li
  • Kanokwan Kulalert
  • Young Hee Oh
  • Emily S Wang
  • Bongjae B Kim
  • Arielle L Yablonovitch
  • Jacqueline J Tao
  • Xiao Dong Su
  • Richard K Plemper
  • Yunwen Huo
  • Stefanie A Krumm
  • Mariya Chavarha
  • Ying Yang
  • Yang Geng
  • Noo Li Jeon
  • Jörg Wiedenmann
  • Mark H Ellisman
  • Mason R Mackey
  • Michelle A Baird
  • Hyung Joon Kim
  • Paula J Cranfill
  • Michael R McKeown

Detail Information

Publications13

  1. pmc TimeSTAMP tagging of newly synthesized proteins
    Michael Z Lin
    Department of Pediatrics and Programs in Gene Therapy and Molecular Imaging, Stanford University, Stanford, California, USA
    Curr Protoc Protein Sci . 2010
    ..Addition of a specific protease inhibitor then allows preservation of the tag on subsequently synthesized proteins. Finally, the tag is detected by immunological methods...
  2. doi request reprint Beyond the rainbow: new fluorescent proteins brighten the infrared scene
    Michael Z Lin
    Departments of Pediatrics and Bioengineering, Stanford University, Stanford, California, USA
    Nat Methods 8:726-8. 2011
    ..Two fluorescent proteins that emit in the far-red and infrared range for imaging applications in cells and in vivo are described...
  3. pmc Improving FRET dynamic range with bright green and red fluorescent proteins
    Amy J Lam
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nat Methods 9:1005-12. 2012
    ..These improvements enhance detection of transient biochemical events such as neuronal action-potential firing and RhoA activation in growth cones...
  4. doi request reprint Cell-Type-Specific Optical Recording of Membrane Voltage Dynamics in Freely Moving Mice
    Jesse D Marshall
    James H Clark Center for Biomedical Engineering and Sciences, Stanford University, Stanford, CA 94305, USA CNC Program, Stanford University, Stanford, CA 94305, USA Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA
    Cell 167:1650-1662.e15. 2016
    ..Overall, TEMPO allows the deconstruction of normal and pathologic neurophysiological states into trans-membrane voltage activity patterns of specific cell types...
  5. doi request reprint Fluorescent indicators for simultaneous reporting of all four cell cycle phases
    Bryce T Bajar
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nat Methods 13:993-996. 2016
    ..We combined these new reporters with the previously described Fucci system to create Fucci4, a set of four orthogonal fluorescent indicators that together resolve all cell cycle phases...
  6. pmc Tunable and reversible drug control of protein production via a self-excising degron
    Hokyung K Chung
    Department of Biology, Stanford University, Stanford, California, USA
    Nat Chem Biol 11:713-20. 2015
    ..Furthermore, as SMASh involves only a single genetic modification and does not rely on modulating protein-protein interactions, it should be easy to generalize to multiple biological contexts...
  7. doi request reprint Subcellular Imaging of Voltage and Calcium Signals Reveals Neural Processing In Vivo
    Helen H Yang
    Department of Neurobiology, Stanford University, Stanford, CA 94305, USA
    Cell 166:245-57. 2016
    ..By imaging voltage and calcium signals to map information flow with subcellular resolution, we illuminate where and how critical computations arise. ..
  8. doi request reprint Genetically encoded indicators of neuronal activity
    Michael Z Lin
    Department of Neurobiology, Stanford University, Stanford, California, USA
    Nat Neurosci 19:1142-53. 2016
    ..Our focus is on how indicator characteristics relate to their use in living animals and on likely areas of future progress. ..
  9. pmc Improving brightness and photostability of green and red fluorescent proteins for live cell imaging and FRET reporting
    Bryce T Bajar
    Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA
    Sci Rep 6:20889. 2016
    ..Finally, using mClover3 and mRuby3, we engineered an improved version of the CaMKIIα reporter Camuiα with a larger response amplitude. ..
  10. pmc Designs and sensing mechanisms of genetically encoded fluorescent voltage indicators
    François St-Pierre
    Department of Pediatrics, Stanford University, Stanford, CA, USA Department of Bioengineering, Stanford University, Stanford, CA, USA
    Curr Opin Chem Biol 27:31-8. 2015
    ..To guide neuroscientists in choosing an appropriate sensor for their applications, we also describe operating trade-offs of each class of voltage indicators. ..
  11. pmc High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensor
    François St-Pierre
    1 Department of Bioengineering, Stanford University, Stanford, California, USA 2 Department of Pediatrics, Stanford University, Stanford, California, USA
    Nat Neurosci 17:884-9. 2014
    ..With a favorable combination of brightness, dynamic range and speed, ASAP1 enables continuous monitoring of membrane potential in neurons at kilohertz frame rates using standard epifluorescence microscopy...
  12. pmc Photoswitchable fluorescent proteins: ten years of colorful chemistry and exciting applications
    Xin X Zhou
    Department of Bioengineering, Stanford University, Mailcode 5164, Stanford, CA 94305, United States
    Curr Opin Chem Biol 17:682-90. 2013
    ..Applications of RSFPs include new types of live-cell superresolution imaging, tracking of protein movements and interactions, information storage, and optical control of protein activity. ..
  13. pmc Fluorescent and photo-oxidizing TimeSTAMP tags track protein fates in light and electron microscopy
    Margaret T Butko
    Department of Pharmacology and Howard Hughes Medical Institute, University of California San Diego, La Jolla, California, USA
    Nat Neurosci 15:1742-51. 2012
    ..These results demonstrate the versatility of the TimeSTAMP approach for visualizing newly synthesized proteins in neurons...