Gordon Li

Summary

Affiliation: Stanford University
Country: USA

Publications

  1. doi request reprint The epidermal growth factor variant III peptide vaccine for treatment of malignant gliomas
    Gordon Li
    Department of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive, Edwards Building Room 213, Stanford, CA 94305, USA
    Neurosurg Clin N Am 21:87-93. 2010
  2. pmc Expression of epidermal growth factor variant III (EGFRvIII) in pediatric diffuse intrinsic pontine gliomas
    Gordon Li
    Department of Neurosurgery, Stanford University Medical Center, Stanford, CA 94305, USA
    J Neurooncol 108:395-402. 2012
  3. ncbi request reprint CyberKnife rhizotomy for facetogenic back pain: a pilot study
    Gordon Li
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA
    Neurosurg Focus 23:E2. 2007
  4. ncbi request reprint Irradiation of glomus jugulare tumors: a historical perspective
    Gordon Li
    Department of Neurosurgery, Stanford University Medical Center, Stanford, California 94305, USA
    Neurosurg Focus 23:E13. 2007
  5. doi request reprint Effects of age and comorbidities on complication rates and adverse outcomes after lumbar laminectomy in elderly patients
    Gordon Li
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA
    Spine (Phila Pa 1976) 33:1250-5. 2008
  6. doi request reprint Perioperative management of ventriculoperitoneal shunts during abdominal surgery
    Gordon Li
    Department of Neurosurgery, Stanford University Medical Center, Stanford, CA 94305, USA
    Surg Neurol 70:492-5; discussion 495-7. 2008
  7. doi request reprint Targeting a glioblastoma cancer stem-cell population defined by EGF receptor variant III
    David R Emlet
    Authors Affiliations Brain Tumor Research Laboratories, Program in Cancer Biology, Stanford University Medical Center, Stanford Department of Pathology, Stanford University Medical Center, Stanford Institute of Stem Cell Biology and Regenerative Medicine, Stanford University Medical Center, Stanford Department of Neurosurgery, Stanford University School of Medicine, Stanford Veterans Affairs Palo Alto Health Care System, Palo Alto, California Department of Physiology and Pharmacology, Institute for Biomedical Research, School of Medicine, University of Salamanca, Salamanca, Spain Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, Massachusetts and Department of Gastroenterology, Henan Provincial People s Hospital, Zhengzhou, Henan, People s Republic of China
    Cancer Res 74:1238-49. 2014
  8. pmc Radiosurgery of glomus jugulare tumors: a meta-analysis
    Zachary D Guss
    Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Int J Radiat Oncol Biol Phys 81:e497-502. 2011
  9. doi request reprint Pineal parenchymal tumor of intermediate differentiation: clinicopathological report and analysis of epidermal growth factor receptor variant III expression
    Gordon Li
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305, USA
    Neurosurgery 66:963-8; discussion 968. 2010
  10. doi request reprint Radiosurgery for glomus jugulare: history and recent progress
    Zachary D Guss
    Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Neurosurg Focus 27:E5. 2009

Collaborators

Detail Information

Publications38

  1. doi request reprint The epidermal growth factor variant III peptide vaccine for treatment of malignant gliomas
    Gordon Li
    Department of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive, Edwards Building Room 213, Stanford, CA 94305, USA
    Neurosurg Clin N Am 21:87-93. 2010
    ..In this article, the authors discuss the preclinical data that led to the human trials and the exciting preliminary data from the clinical trials...
  2. pmc Expression of epidermal growth factor variant III (EGFRvIII) in pediatric diffuse intrinsic pontine gliomas
    Gordon Li
    Department of Neurosurgery, Stanford University Medical Center, Stanford, CA 94305, USA
    J Neurooncol 108:395-402. 2012
    ..We were therefore able to detect EGFRvIII expression in 6 of 11 DIPG cases. These data suggest that EGFRvIII warrants investigation as a target for these deadly pediatric tumors...
  3. ncbi request reprint CyberKnife rhizotomy for facetogenic back pain: a pilot study
    Gordon Li
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA
    Neurosurg Focus 23:E2. 2007
    ..The authors used CyberKnife radiosurgery to denervate affected facet joints with the goal of obtaining a less invasive yet more thorough and durable antinociceptive rhizotomy...
  4. ncbi request reprint Irradiation of glomus jugulare tumors: a historical perspective
    Gordon Li
    Department of Neurosurgery, Stanford University Medical Center, Stanford, California 94305, USA
    Neurosurg Focus 23:E13. 2007
    ..In this article the authors discuss the history of radiation therapy for glomus jugulare tumors, focusing on recent radiosurgical results...
  5. doi request reprint Effects of age and comorbidities on complication rates and adverse outcomes after lumbar laminectomy in elderly patients
    Gordon Li
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA
    Spine (Phila Pa 1976) 33:1250-5. 2008
    ..This is a retrospective cohort study using the National Inpatient Sample database...
  6. doi request reprint Perioperative management of ventriculoperitoneal shunts during abdominal surgery
    Gordon Li
    Department of Neurosurgery, Stanford University Medical Center, Stanford, CA 94305, USA
    Surg Neurol 70:492-5; discussion 495-7. 2008
    ..There is currently no established set of guidelines for this scenario. The objective of this study was to determine the risks and standard of practice for patients with VPSs undergoing abdominal surgery...
  7. doi request reprint Targeting a glioblastoma cancer stem-cell population defined by EGF receptor variant III
    David R Emlet
    Authors Affiliations Brain Tumor Research Laboratories, Program in Cancer Biology, Stanford University Medical Center, Stanford Department of Pathology, Stanford University Medical Center, Stanford Institute of Stem Cell Biology and Regenerative Medicine, Stanford University Medical Center, Stanford Department of Neurosurgery, Stanford University School of Medicine, Stanford Veterans Affairs Palo Alto Health Care System, Palo Alto, California Department of Physiology and Pharmacology, Institute for Biomedical Research, School of Medicine, University of Salamanca, Salamanca, Spain Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, Massachusetts and Department of Gastroenterology, Henan Provincial People s Hospital, Zhengzhou, Henan, People s Republic of China
    Cancer Res 74:1238-49. 2014
    ..This work demonstrates that a mutated oncogene can have CSC-specific expression and be used to specifically target this population...
  8. pmc Radiosurgery of glomus jugulare tumors: a meta-analysis
    Zachary D Guss
    Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Int J Radiat Oncol Biol Phys 81:e497-502. 2011
    ..In the present study, we report on a systematic review and meta-analysis of the available published data on the radiosurgical management of glomus jugulare tumors...
  9. doi request reprint Pineal parenchymal tumor of intermediate differentiation: clinicopathological report and analysis of epidermal growth factor receptor variant III expression
    Gordon Li
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305, USA
    Neurosurgery 66:963-8; discussion 968. 2010
    ..Therapies targeting EGFRvIII are currently being investigated in clinical and preclinical trials...
  10. doi request reprint Radiosurgery for glomus jugulare: history and recent progress
    Zachary D Guss
    Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Neurosurg Focus 27:E5. 2009
    ..These preliminary reports demonstrate that the use of radiosurgery as a primary treatment for glomus jugulare should be extended to encompass more of the patients who are currently assigned to microsurgical treatment...
  11. doi request reprint Targeting EGF receptor variant III: tumor-specific peptide vaccination for malignant gliomas
    Catherine A Del Vecchio
    Stanford University, 1201 Welch Road, MSLS P105, Stanford, CA 94305, USA
    Expert Rev Vaccines 11:133-44. 2012
    ..Rindopepimut therefore represents a very promising therapy for patients with GBM...
  12. ncbi request reprint CyberKnife radiosurgical rhizotomy for the treatment of atypical trigeminal nerve pain
    Chirag G Patil
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305 5327, USA
    Neurosurg Focus 23:E9. 2007
    ..This study represents the first report of the treatment of atypical TN with frameless CyberKnife stereotactic radiosurgery (SRS)...
  13. doi request reprint Cyberknife for brain metastases of malignant melanoma and renal cell carcinoma
    Wendy Hara
    Department of Radiation Oncology, Stanford University, Stanford Cancer Center, 875 Blake Wilbur Drive, Stanford, CA 94305 5847, USA
    Neurosurgery 64:A26-32. 2009
    ..To evaluate the efficacy of CyberKnife (Accuray, Inc., Sunnyvale, CA) stereotactic radiosurgery (SRS) for patients with brain metastases of malignant melanoma and renal cell carcinoma...
  14. doi request reprint Repeat Courses of Stereotactic Radiosurgery (SRS), Deferring Whole-Brain Irradiation, for New Brain Metastases After Initial SRS
    David B Shultz
    Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California
    Int J Radiat Oncol Biol Phys 92:993-9. 2015
    ..To report the outcomes of repeat stereotactic radiosurgery (SRS), deferring whole-brain radiation therapy (WBRT), for distant intracranial recurrences and identify factors associated with prolonged overall survival (OS)...
  15. pmc Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma
    Michelle Monje
    Department of Neurology, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University Medical Center, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 108:4453-8. 2011
    ..Together, these findings provide a foundation for understanding the cellular and molecular origins of DIPG, and suggest that the Hh pathway represents a potential therapeutic target in this devastating pediatric tumor...
  16. doi request reprint The predictive value of serum myeloperoxidase for vasospasm in patients with aneurysmal subarachnoid hemorrhage
    Michael Lim
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Neurosurg Rev 35:413-9; discussion 419. 2012
    ..3%). Elevated serum MPO correlates with clinically evident vasospasm following aneurysmal SAH. The potential utility of MPO as a marker of vasospasm is discussed...
  17. pmc Development of an EGFRvIII specific recombinant antibody
    Puja Gupta
    Brain Tumor Research Laboratories, Department of Neurosurgery, and Program in Cancer Biology, Stanford University Medical Center, Stanford, CA 94305, USA
    BMC Biotechnol 10:72. 2010
    ..Furthermore, a monoclonal antibody to EGFRvIII is not readily available to the scientific community...
  18. doi request reprint Combining immunotherapy with radiation for the treatment of glioblastoma
    Kevin K H Chow
    Department of Neurosurgery, Stanford University Medical Center, Stanford, CA, 94304, USA
    J Neurooncol 123:459-64. 2015
    ..Here we review this evidence and discuss considerations for combined therapy. ..
  19. pmc Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse
    Ye Zhang
    Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA Electronic address
    Neuron 89:37-53. 2016
    ..These data represent some of the first cell-type-specific molecular profiles of the healthy and diseased human brain. ..
  20. doi request reprint Pathology: commonly monitored glioblastoma markers: EFGR, EGFRvIII, PTEN, and MGMT
    Joaquin Q Camara-Quintana
    Department of Neurosurgery, Stanford University, 1201 Welch Road, MSLS P309, Stanford, CA 94305, USA
    Neurosurg Clin N Am 23:237-46, viii. 2012
    ....
  21. pmc Casein Kinase 2: a novel player in glioblastoma therapy and cancer stem cells
    Maya Agarwal
    Department of Neurosurgery, Stanford University Medical Center, Stanford, CA 94305, USA
    J Mol Genet Med 8:. 2013
    ..The development of CK2 targeted inhibitors, starting with CX-4945, may lead to a new class of more effective cancer therapies...
  22. pmc Immune Evasion Strategies of Glioblastoma
    Seyed Mostafa Razavi
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA
    Front Surg 3:11. 2016
    ..Further understanding of these strategies and the biology of this tumor will pave the way for developing novel immunotherapeutic approaches for treatment of GBM. ..
  23. pmc Intracranial fat migration: A newly described complication of autologous fat repair of a cerebrospinal fluid leak following supracerebellar infratentorial approach
    Cassie A Ludwig
    Stanford University School of Medicine, Department of Neurosurgery, Edwards, R229 Stanford, CA 94305 5327, USA Electronic address
    Int J Surg Case Rep 7:1-5. 2015
    ..Intracranial fat migration following autologous fat graft and placement of a lumbar drain for cerebrospinal fluid leak after pineal cyst resection surgery has not been previously reported...
  24. pmc γ-Glutamyl transferase 7 is a novel regulator of glioblastoma growth
    Timothy T Bui
    Department of Neurosurgery, Stanford University School of Medicine, Institute for Stem Cell Biology and Regenerative Medicine, 1201 Welch Rd P309, Stanford, CA, 94305 5487, USA
    BMC Cancer 15:225. 2015
    ..Since other members of the GGT family were found to be altered in a variety of cancers, we hypothesized that GGT7 could regulate GBM growth and formation...
  25. pmc The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors
    Stephen B Willingham
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University Medical Center, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 109:6662-7. 2012
    ..CD47 is therefore a validated target for cancer therapies...
  26. doi request reprint Passive antibody-mediated immunotherapy for the treatment of malignant gliomas
    Siddhartha Mitra
    Department of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive, Edwards Building Room 200, Stanford, CA 94305, USA
    Neurosurg Clin N Am 21:67-76. 2010
    ..In this article, the authors discuss the preclinical and clinical studies that have used passive antibody-mediated immunotherapy, otherwise known as serotherapy, for the treatment of malignant gliomas...
  27. doi request reprint Frameless, electromagnetic image-guided ventriculostomy for ventriculoperitoneal shunt and Ommaya reservoir placement
    Linda W Xu
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA Electronic address
    Clin Neurol Neurosurg 147:46-52. 2016
    ..Here we report our experience using frameless, electromagnetic (EM) image-guidance as a fast and low risk method of ensuring accurate ventriculostomy catheter placement...
  28. pmc The future of glioblastoma therapy: synergism of standard of care and immunotherapy
    Mira A Patel
    Department of Neurosurgery, The Johns Hopkins University School of Medicine, 600 N Wolfe St, Phipps Building Rm 123, Baltimore, MD 21287, USA
    Cancers (Basel) 6:1953-85. 2014
    ..Here, we review current GBM therapy and the evidence for combination of immune checkpoint inhibitors, DC and peptide vaccines with the current standard of care. ..
  29. doi request reprint Craniotomy for Resection of Meningioma: An Age-Stratified Analysis of the MarketScan Longitudinal Database
    Ian D Connolly
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA
    World Neurosurg 84:1864-70. 2015
    ..We sought to describe complications after resection for meningioma with the use of longitudinal administrative data, which our group has shown recently to be superior to nonlongitudinal administrative data...
  30. doi request reprint Dose-Response Modeling of the Visual Pathway Tolerance to Single-Fraction and Hypofractionated Stereotactic Radiosurgery
    Susan M Hiniker
    Department of Radiation Oncology, Stanford University, Stanford, CA
    Semin Radiat Oncol 26:97-104. 2016
    ..Further investigation would refine the estimated normal tissue complication probability for SRS near the optic apparatus. ..
  31. doi request reprint Glioblastoma Multiforme Recurrence: An Exploratory Study of (18)F FPPRGD2 PET/CT
    Andrei Iagaru
    From the Division of Nuclear Medicine and Molecular Imaging A I, C M, E M, Department of Radiology, Neuroradiology Section G Z, N F, Division of Neurosurgery G H, G L, and Division of Neuro Oncology S N, L R, Stanford University Medical Center, 300 Pasteur Dr, Room H 2200, Stanford, CA 94305 and Departments of Radiology, Bioengineering, Materials Science, and Engineering, Stanford University School of Medicine, Stanford, Calif S S G
    Radiology 277:497-506. 2015
    ....
  32. doi request reprint Glioblastoma antigen discovery--foundations for immunotherapy
    Tej D Azad
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA
    J Neurooncol 123:347-58. 2015
    ..Here we discuss tumor-associated antigens that have been targeted for GBM therapy, strategies for discovery of novel antigens, and the theory of epitope spreading as it applies to GBM immunotherapy. ..
  33. doi request reprint Endovascular therapies for malignant gliomas: Challenges and the future
    YouRong Sophie Su
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA
    J Clin Neurosci 26:26-32. 2016
    ....
  34. doi request reprint Atypical and rare variants of central neurocytomas
    Omar Choudhri
    Department of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive MC5327, Stanford, CA 94305, USA
    Neurosurg Clin N Am 26:91-8. 2015
    ..Other less aggressive variants of central neurocytomas, including liponeurocytomas, ganglioneurocytomas, and pigmented neurocytomas, are also discussed. ..
  35. pmc Current vaccine trials in glioblastoma: a review
    Linda W Xu
    Department of Neurosurgery, Stanford University Medical Center, Stanford, CA 94304, USA
    J Immunol Res 2014:796856. 2014
    ..If the results of these randomized trials show a survival benefit, immunotherapy will become a standard part of the treatment of this devastating disease. ..
  36. doi request reprint EGF receptor variant III as a target antigen for tumor immunotherapy
    Gordon Li
    Department of Neurosurgery, Stanford University School of Medicine, 300 Pasteur Drive, Edwards Building Room 213, Stanford, CA 94305, USA
    Expert Rev Vaccines 7:977-85. 2008
    ....
  37. ncbi request reprint Intracranial hypotension from intrathecal baclofen pump insertion. A case report and review of the literature
    Shivanand P Lad
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA
    Stereotact Funct Neurosurg 86:75-9. 2008
    ..In this report, we present a case of intracranial hypotension secondary to baclofen pump placement. We review the major clinical findings, neuroimaging abnormalities, key diagnostic features as well as treatment options...
  38. ncbi request reprint Cerebral perfusion imaging in vasospasm
    Shivanand P Lad
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA
    Neurosurg Focus 21:E7. 2006
    ....